BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0187.0016.p (341 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_02189481.1| 2-dehydropantoate 2-reductase [alpha proteoba... 253 3e-65 ref|YP_004334326.1| 2-dehydropantoate 2-reductase [Pseudonocardi... 245 6e-63 ref|YP_001274710.1| 2-dehydropantoate 2-reductase [Roseiflexus s... 244 1e-62 ref|YP_547395.1| 2-dehydropantoate 2-reductase [Polaromonas sp. ... 244 1e-62 ref|YP_551944.1| 2-dehydropantoate 2-reductase [Polaromonas sp. ... 242 5e-62 >ref|ZP_02189481.1| 2-dehydropantoate 2-reductase [alpha proteobacterium BAL199] gb|EDP63647.1| 2-dehydropantoate 2-reductase [alpha proteobacterium BAL199] Length = 306 Score = 253 bits (647), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 134/289 (46%), Positives = 186/289 (64%), Gaps = 1/289 (0%) Query: 51 AALAHAGADVTFIARGAHLAAMRSEGLKVQGGRGETHLVPTQATDDPASV-GPVDIVLFC 109 A LA AG +V F+ARGAHL A+R G +++G RG+ L ATD+ A++ PVD+VLF Sbjct: 17 AHLARAGHEVVFVARGAHLEAIRRNGFRLEGARGDIVLPSVGATDNLATLDSPVDVVLFA 76 Query: 110 VKLWDVESAGQHIRPMVGPDTAVIPLQNGIDAPDRLVSILGRNAVMGGVAQISASIIKPG 169 VKL+D E+AG IRP+VGP T VI LQNG+D PDRL +++G AV+GG A +SA I +PG Sbjct: 77 VKLYDTEAAGVAIRPVVGPRTMVINLQNGVDGPDRLATVIGTEAVLGGAAYVSALIAEPG 136 Query: 170 VINQVGTFMRMIFGELDGRITPRGKALLDLCLKAGFDATLSEQINTELWMKFIGLATNAG 229 V+ +++FGELDG ++ R A D C AGF+A +S I LW KF+ LATNAG Sbjct: 137 VVRYTSEMSKVVFGELDGTVSDRALAFRDSCRSAGFEAEVSSDIRAALWDKFVLLATNAG 196 Query: 230 MTAVTRLPIGKLRDDPDLRPLFVSACEEIIAIAHASGIKLPSDALTKVLDFIGHAPPAMK 289 +T + R P G++ DP++ L +E++A+A A+GI+ +D + + + PP M Sbjct: 197 LTTLLRKPAGEVYTDPEIMALAQELMKEVVAVAAAAGIRTSADIIERSIALSKSFPPGMY 256 Query: 290 ASMALDLERGNRLELPWLNGKVVELGRKLGVPTPTHDMLYAVLKPYAMG 338 ASM DL RG R+E+ L+G V G +LGVP P H ++ LKPY G Sbjct: 257 ASMYHDLARGRRIEVASLSGLVARRGAELGVPVPHHTSIWCALKPYVDG 305 >ref|YP_004334326.1| 2-dehydropantoate 2-reductase [Pseudonocardia dioxanivorans CB1190] gb|AEA26473.1| 2-dehydropantoate 2-reductase [Pseudonocardia dioxanivorans CB1190] Length = 310 Score = 245 bits (626), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 136/301 (45%), Positives = 178/301 (59%) Query: 35 MRIAVVGAGGVGGGFGAALAHAGADVTFIARGAHLAAMRSEGLKVQGGRGETHLVPTQAT 94 MRIAV+G GGVGG FGA LA G DV F+ARG HL A+R GL+V G+ L T Sbjct: 1 MRIAVMGTGGVGGYFGARLAEGGHDVAFVARGRHLQALRENGLRVLSPLGDLTLPDVTVT 60 Query: 95 DDPASVGPVDIVLFCVKLWDVESAGQHIRPMVGPDTAVIPLQNGIDAPDRLVSILGRNAV 154 DDPA + PVD+VLF VKLWD E A + P+VG TAV+ QNG+ + L +LG V Sbjct: 61 DDPAELDPVDLVLFAVKLWDTEQAAAQVAPLVGERTAVVSFQNGVAKDEILRRVLGDRHV 120 Query: 155 MGGVAQISASIIKPGVINQVGTFMRMIFGELDGRITPRGKALLDLCLKAGFDATLSEQIN 214 MGGV I+ASI +PGVI T R++FGE DG + R AL D C+ +G D +S++I Sbjct: 121 MGGVCYIAASIAEPGVIRHANTLQRLVFGEYDGTASARTAALHDACVDSGIDVEVSDRIE 180 Query: 215 TELWMKFIGLATNAGMTAVTRLPIGKLRDDPDLRPLFVSACEEIIAIAHASGIKLPSDAL 274 +W KF+ L +G T++ R PIG +RD+P R +E++ + A G+ LP D Sbjct: 181 QTIWEKFVFLVGLSGTTSLARTPIGPIRDEPRARAFLRDVMDEVVRVGRAQGVALPEDYA 240 Query: 275 TKVLDFIGHAPPAMKASMALDLERGNRLELPWLNGKVVELGRKLGVPTPTHDMLYAVLKP 334 L F+ P M +SM DLE GNRLEL WL+G VV LGV P + + +L Sbjct: 241 DDRLAFVDTIPATMSSSMHHDLEHGNRLELAWLSGDVVARAADLGVAAPANRAIADILSV 300 Query: 335 Y 335 + Sbjct: 301 H 301 >ref|YP_001274710.1| 2-dehydropantoate 2-reductase [Roseiflexus sp. RS-1] gb|ABQ88760.1| 2-dehydropantoate 2-reductase [Roseiflexus sp. RS-1] Length = 315 Score = 244 bits (624), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 141/300 (47%), Positives = 187/300 (62%) Query: 35 MRIAVVGAGGVGGGFGAALAHAGADVTFIARGAHLAAMRSEGLKVQGGRGETHLVPTQAT 94 MRIAVVG GGVGG FG LA AGADV FIARG +LAA+R +GL+++ G+ H+ P QAT Sbjct: 1 MRIAVVGVGGVGGYFGGRLAQAGADVIFIARGDNLAALREQGLRIESIIGDAHVAPVQAT 60 Query: 95 DDPASVGPVDIVLFCVKLWDVESAGQHIRPMVGPDTAVIPLQNGIDAPDRLVSILGRNAV 154 DDPA GPVD+VL K W ++ A +RP++GP+T V+PL NG++A DRL + LG + Sbjct: 61 DDPAQAGPVDMVLVATKTWQLDEAIDLMRPLIGPETGVVPLLNGVEASDRLAAALGESHA 120 Query: 155 MGGVAQISASIIKPGVINQVGTFMRMIFGELDGRITPRGKALLDLCLKAGFDATLSEQIN 214 + G+ I + + PGV+ G +IFGE D R T R +AL D +AG T+ I+ Sbjct: 121 LNGICYIFVARVAPGVVRHSGIHPLIIFGERDNRRTARVEALRDWLERAGVRVTIPPDID 180 Query: 215 TELWMKFIGLATNAGMTAVTRLPIGKLRDDPDLRPLFVSACEEIIAIAHASGIKLPSDAL 274 E+W KF+ AT +G+ AVTR P+G LR+ P+ RPLF+ EI+A+A A G+ L +A+ Sbjct: 181 AEVWRKFVFGATTSGLGAVTRAPMGLLRELPETRPLFIQGMREIVAVAQACGVALGEEAV 240 Query: 275 TKVLDFIGHAPPAMKASMALDLERGNRLELPWLNGKVVELGRKLGVPTPTHDMLYAVLKP 334 T L + P ASM D+ G EL NG V LG GVPTP H +YA L P Sbjct: 241 TAALAQLDALPYETTASMQRDIMAGRPSELEAQNGAVARLGAAAGVPTPLHAFIYATLLP 300 >ref|YP_547395.1| 2-dehydropantoate 2-reductase [Polaromonas sp. JS666] gb|ABE42497.1| ketopantoate reductase [Polaromonas sp. JS666] Length = 307 Score = 244 bits (623), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 134/304 (44%), Positives = 183/304 (60%) Query: 35 MRIAVVGAGGVGGGFGAALAHAGADVTFIARGAHLAAMRSEGLKVQGGRGETHLVPTQAT 94 MRIAV+G GGVGG FGA LA AG DV+F+ARG LAA+R GL+V+ G HL T Sbjct: 1 MRIAVMGTGGVGGYFGARLAKAGHDVSFVARGRQLAAIRDTGLRVESPLGNLHLKKVSVT 60 Query: 95 DDPASVGPVDIVLFCVKLWDVESAGQHIRPMVGPDTAVIPLQNGIDAPDRLVSILGRNAV 154 D PA +GP DIVLF VKLWD A + I+P++G TAV+ QNG+ D L LG V Sbjct: 61 DTPADIGPADIVLFGVKLWDTAEAAEAIKPLIGEHTAVVSFQNGVVKDDILRQTLGEAHV 120 Query: 155 MGGVAQISASIIKPGVINQVGTFMRMIFGELDGRITPRGKALLDLCLKAGFDATLSEQIN 214 +GGV I+A+I +PG+I G +++FGE DG T R D C++AG D +S++I Sbjct: 121 IGGVCYIAATIAEPGLIRHSGAMQKLVFGEYDGTSTARVARFRDACVEAGIDVEISDRIG 180 Query: 215 TELWMKFIGLATNAGMTAVTRLPIGKLRDDPDLRPLFVSACEEIIAIAHASGIKLPSDAL 274 +W KF+ L +G T VTR PIG +R + R +E++ +A A G+++ D Sbjct: 181 QTIWEKFVFLVGLSGTTTVTRTPIGTVRANERARAFLRDVMDEVVRVARADGVQVAEDYA 240 Query: 275 TKVLDFIGHAPPAMKASMALDLERGNRLELPWLNGKVVELGRKLGVPTPTHDMLYAVLKP 334 L F P M +SM D+ERG+RLE+ WL+G VV G +LGV TP + + +L Sbjct: 241 NNRLAFCDQLPATMTSSMHGDIERGSRLEVQWLSGDVVHRGARLGVATPCNRAILDILSV 300 Query: 335 YAMG 338 ++ G Sbjct: 301 HSEG 304 >ref|YP_551944.1| 2-dehydropantoate 2-reductase [Polaromonas sp. JS666] gb|ABE47046.1| 2-dehydropantoate 2-reductase [Polaromonas sp. JS666] Length = 307 Score = 242 bits (618), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 134/304 (44%), Positives = 182/304 (59%) Query: 35 MRIAVVGAGGVGGGFGAALAHAGADVTFIARGAHLAAMRSEGLKVQGGRGETHLVPTQAT 94 MRIAV+G GGVGG FGA LA AG DV+F+ARG LAA+R GL+V+ G HL T Sbjct: 1 MRIAVMGTGGVGGYFGARLAKAGHDVSFVARGRQLAAIRDTGLRVESPLGNLHLKKVSVT 60 Query: 95 DDPASVGPVDIVLFCVKLWDVESAGQHIRPMVGPDTAVIPLQNGIDAPDRLVSILGRNAV 154 D PA +GP DIVLF VKLWD A + I+P++G TAV+ QNG+ D L LG V Sbjct: 61 DTPADIGPADIVLFGVKLWDTADAAEAIKPLIGEHTAVVSFQNGVVKDDILRQTLGEAHV 120 Query: 155 MGGVAQISASIIKPGVINQVGTFMRMIFGELDGRITPRGKALLDLCLKAGFDATLSEQIN 214 +GGV I+A+I +PG+I G +++FGE DG T R D C++AG D +S++I Sbjct: 121 IGGVCYIAATIAEPGLIRHSGAMQKLVFGEYDGTSTARVARFRDACVEAGIDVEISDRIG 180 Query: 215 TELWMKFIGLATNAGMTAVTRLPIGKLRDDPDLRPLFVSACEEIIAIAHASGIKLPSDAL 274 +W KF+ L +G T VTR PIG +R + R +E++ +A A G+++ D Sbjct: 181 QTIWEKFVFLVGLSGTTTVTRTPIGTVRANERARAFLRDVMDEVVRVARADGVQVAEDYA 240 Query: 275 TKVLDFIGHAPPAMKASMALDLERGNRLELPWLNGKVVELGRKLGVPTPTHDMLYAVLKP 334 L F M +SM DLERG+RLE+ WL+G VV G +LGV TP + + +L Sbjct: 241 NNRLAFCDQLAATMTSSMHGDLERGSRLEVQWLSGDVVHRGARLGVATPCNRAILDILSV 300 Query: 335 YAMG 338 ++ G Sbjct: 301 HSEG 304