BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0176.0008.p (532 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_770432.1| alpha-isopropylmalate/homocitrate synthase fami... 987 0.0 ref|YP_001206643.1| putative alpha-isopropylmalate/homocitrate s... 965 0.0 ref|ZP_08629374.1| (R)-citramalate synthase [Bradyrhizobiaceae b... 965 0.0 ref|YP_001239500.1| putative alpha-isopropylmalate/homocitrate s... 955 0.0 ref|YP_531962.1| putative alpha-isopropylmalate/homocitrate synt... 922 0.0 >ref|NP_770432.1| alpha-isopropylmalate/homocitrate synthase family transferase [Bradyrhizobium japonicum USDA 110] dbj|BAC49057.1| 2-isopropylmalate synthase [Bradyrhizobium japonicum USDA 110] Length = 537 Score = 987 bits (2552), Expect = 0.0, Method: Compositional matrix adjust. Identities = 473/530 (89%), Positives = 502/530 (94%) Query: 3 RERLYLFDTTLRDGAQTNGVDFTLQDKQVISGMLDALGIDYVEGGYPGANPTDSEFFSRK 62 +ERLYLFDTTLRDGAQTNGVDFTL DKQ+I+ MLD LGIDYVEGGYPGANPTD+EFF K Sbjct: 8 KERLYLFDTTLRDGAQTNGVDFTLTDKQIIAAMLDELGIDYVEGGYPGANPTDTEFFGSK 67 Query: 63 PDFEHARFTAFGMTRRPGRSASNDPGLAGILEAKADAICFVAKSSAYQVRVALETTNEEN 122 P HARFTAFGMTRR GRS SNDPG+AG+LEAKADAICFVAKSSAYQVRVALETT EEN Sbjct: 68 PKLNHARFTAFGMTRRAGRSVSNDPGVAGLLEAKADAICFVAKSSAYQVRVALETTKEEN 127 Query: 123 LASIRDSVAAAKALGREVMVDCEHFFDGYKENRDYALACAKAAYQSGARWVVLCDTNGGT 182 LASIRDSVAAAKA GREVM+DCEHFFDGYKE+ +ALACAKAAY++GARWVVLCDTNGGT Sbjct: 128 LASIRDSVAAAKAAGREVMLDCEHFFDGYKEDSSFALACAKAAYEAGARWVVLCDTNGGT 187 Query: 183 MPHEIETIVGDVVKHVPGAYLGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERCGN 242 MP+E+E IV +V +H+PGA++GIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERCGN Sbjct: 188 MPNEVEAIVTEVTRHIPGAHVGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERCGN 247 Query: 243 ANLCSLIPTLKLKQEFSDKFEIGVTTEKLATLMKVSRTLDDMLNRAPNRHAAYVGESAFV 302 ANLCSLIPTLKLKQEF+D FEIGVT EKLATL+KVSRTLDDMLNR PNRHAAYVGESAFV Sbjct: 248 ANLCSLIPTLKLKQEFADAFEIGVTPEKLATLVKVSRTLDDMLNRVPNRHAAYVGESAFV 307 Query: 303 TKTGIHASAVMKDPQTYEHVLPELVGNHRKVLVSDQAGRSNVMAELDRAGIAYDKSDPRL 362 TKTGIHASAV+KDPQTYEHVLPELVGNHRKVLVSDQAGRSNV+AELDRAGIAY+KSDP+L Sbjct: 308 TKTGIHASAVLKDPQTYEHVLPELVGNHRKVLVSDQAGRSNVIAELDRAGIAYEKSDPKL 367 Query: 363 TRLVEELKEREAAGFAYESANASFDLLARRTLGKVPEYFKVEQFDVNVEQRYNANGQRVT 422 TRLVEELKEREAAG+AYESANASFDLLARRTLGKVP YF+VEQFDVNVEQRYNA G+RVT Sbjct: 368 TRLVEELKEREAAGYAYESANASFDLLARRTLGKVPHYFEVEQFDVNVEQRYNALGERVT 427 Query: 423 VALAVVKVDVDGERLISAAEGNGPVNALDVALRKDLGKYQKYIDGLKLIDYRVRILNGGT 482 VALAVVKVDV GE LISAAEGNGPVNALDVALRKDLGKYQKYI+GLKLIDYRVRILNGGT Sbjct: 428 VALAVVKVDVAGEHLISAAEGNGPVNALDVALRKDLGKYQKYIEGLKLIDYRVRILNGGT 487 Query: 483 EAVTRVLIESEDETGESWTTVGVSPNIIDASFQALMDSVFYKLVKSGAQA 532 AVTRVLIESEDE G+SWTTVGVSPNIIDASFQALMDSV YKLVKSGA A Sbjct: 488 GAVTRVLIESEDENGDSWTTVGVSPNIIDASFQALMDSVIYKLVKSGAPA 537 >ref|YP_001206643.1| putative alpha-isopropylmalate/homocitrate synthase family transferase [Bradyrhizobium sp. ORS 278] emb|CAL78426.1| putative isopropylmalate synthase (LeuA-like) [Bradyrhizobium sp. ORS 278] Length = 532 Score = 965 bits (2495), Expect = 0.0, Method: Compositional matrix adjust. Identities = 465/530 (87%), Positives = 495/530 (93%) Query: 1 VSRERLYLFDTTLRDGAQTNGVDFTLQDKQVISGMLDALGIDYVEGGYPGANPTDSEFFS 60 +SRERLYLFDTTLRDGAQTNGVDFTL DKQVI+ +LD LGIDYVEGGYPGANP D+EFF+ Sbjct: 1 MSRERLYLFDTTLRDGAQTNGVDFTLTDKQVIARLLDDLGIDYVEGGYPGANPLDTEFFA 60 Query: 61 RKPDFEHARFTAFGMTRRPGRSASNDPGLAGILEAKADAICFVAKSSAYQVRVALETTNE 120 KP HARFTAFGMTRR GRS SNDPG+A +LEAKADAICFVAKSSAYQVRVALETTNE Sbjct: 61 DKPKLGHARFTAFGMTRRAGRSVSNDPGVAALLEAKADAICFVAKSSAYQVRVALETTNE 120 Query: 121 ENLASIRDSVAAAKALGREVMVDCEHFFDGYKENRDYALACAKAAYQSGARWVVLCDTNG 180 ENLASIRDSV AAKA GREVM+DCEHFFDGYKEN +ALACA+ AY++GARWVVLCDTNG Sbjct: 121 ENLASIRDSVTAAKAAGREVMLDCEHFFDGYKENAAFALACARTAYEAGARWVVLCDTNG 180 Query: 181 GTMPHEIETIVGDVVKHVPGAYLGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERC 240 GTMPHEIE +VG+VVKHVPG +LGIHAHNDTEQAVANSLAAVRAG RQIQGTLNGLGERC Sbjct: 181 GTMPHEIEAVVGEVVKHVPGDHLGIHAHNDTEQAVANSLAAVRAGVRQIQGTLNGLGERC 240 Query: 241 GNANLCSLIPTLKLKQEFSDKFEIGVTTEKLATLMKVSRTLDDMLNRAPNRHAAYVGESA 300 GNANLCSLIPTLKLK EFS++FEIGV+ ++LA LMKVSRTLDDMLNRAPNRHA YVGESA Sbjct: 241 GNANLCSLIPTLKLKAEFSERFEIGVSDQQLAGLMKVSRTLDDMLNRAPNRHAPYVGESA 300 Query: 301 FVTKTGIHASAVMKDPQTYEHVLPELVGNHRKVLVSDQAGRSNVMAELDRAGIAYDKSDP 360 FVTKTGIHASAV+KDP TYEHVLPE VGNHRKVLVSDQAGRSNV+A L+R GI + KSDP Sbjct: 301 FVTKTGIHASAVLKDPHTYEHVLPESVGNHRKVLVSDQAGRSNVIAALERGGIPFSKSDP 360 Query: 361 RLTRLVEELKEREAAGFAYESANASFDLLARRTLGKVPEYFKVEQFDVNVEQRYNANGQR 420 +LTRLVEELKEREA G+AYESANASF+LLARRTLG VPEYF+VEQFDVNVEQRYNA G+R Sbjct: 361 KLTRLVEELKEREALGYAYESANASFELLARRTLGSVPEYFRVEQFDVNVEQRYNALGER 420 Query: 421 VTVALAVVKVDVDGERLISAAEGNGPVNALDVALRKDLGKYQKYIDGLKLIDYRVRILNG 480 VTVALAVVKVDV GERLISAAEGNGPVNALDVALRKDLGKYQ +IDGLKLIDYRVRILNG Sbjct: 421 VTVALAVVKVDVAGERLISAAEGNGPVNALDVALRKDLGKYQGFIDGLKLIDYRVRILNG 480 Query: 481 GTEAVTRVLIESEDETGESWTTVGVSPNIIDASFQALMDSVFYKLVKSGA 530 GTEAVTRVLIESEDETGE WTTVGVSPNIIDASFQALMDSVFYKLVKSGA Sbjct: 481 GTEAVTRVLIESEDETGERWTTVGVSPNIIDASFQALMDSVFYKLVKSGA 530 >ref|ZP_08629374.1| (R)-citramalate synthase [Bradyrhizobiaceae bacterium SG-6C] gb|EGP07867.1| (R)-citramalate synthase [Bradyrhizobiaceae bacterium SG-6C] Length = 532 Score = 965 bits (2494), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/532 (86%), Positives = 499/532 (93%) Query: 1 VSRERLYLFDTTLRDGAQTNGVDFTLQDKQVISGMLDALGIDYVEGGYPGANPTDSEFFS 60 +SRERLYLFDTTLRDGAQTNGVDFTL DKQ+I+ MLD LGIDYVEGGYPGANP+D+EFF+ Sbjct: 1 MSRERLYLFDTTLRDGAQTNGVDFTLHDKQIIANMLDDLGIDYVEGGYPGANPSDTEFFA 60 Query: 61 RKPDFEHARFTAFGMTRRPGRSASNDPGLAGILEAKADAICFVAKSSAYQVRVALETTNE 120 KP F+HA+FTAFGMTRR GRS SNDPG+AG+LEAKADAICFVAKSS YQVRVALETTNE Sbjct: 61 SKPKFDHAKFTAFGMTRRAGRSVSNDPGVAGLLEAKADAICFVAKSSEYQVRVALETTNE 120 Query: 121 ENLASIRDSVAAAKALGREVMVDCEHFFDGYKENRDYALACAKAAYQSGARWVVLCDTNG 180 ENLASIRDSV+AAKA GREVM+DCEHFFDGYKEN +ALACAKAAY SGARWVVLCDTNG Sbjct: 121 ENLASIRDSVSAAKAAGREVMLDCEHFFDGYKENPQFALACAKAAYDSGARWVVLCDTNG 180 Query: 181 GTMPHEIETIVGDVVKHVPGAYLGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERC 240 GTMP+EIE IVG+VVKH+PG ++GIH HNDTEQAVANSLAAVRAGARQIQGTLNGLGERC Sbjct: 181 GTMPNEIEAIVGEVVKHIPGDHVGIHTHNDTEQAVANSLAAVRAGARQIQGTLNGLGERC 240 Query: 241 GNANLCSLIPTLKLKQEFSDKFEIGVTTEKLATLMKVSRTLDDMLNRAPNRHAAYVGESA 300 GNANLCSLIPTLKLK+EF+DKFEIGV+ EKLATL+ SR LDD+LNRAP+RHA YVGESA Sbjct: 241 GNANLCSLIPTLKLKKEFADKFEIGVSDEKLATLVHASRALDDILNRAPDRHAPYVGESA 300 Query: 301 FVTKTGIHASAVMKDPQTYEHVLPELVGNHRKVLVSDQAGRSNVMAELDRAGIAYDKSDP 360 FVTKTGIHASAV+KDPQTYEH+ PE VGNHRKVLVSDQAGRSNV+AEL+RAGI +DK+DP Sbjct: 301 FVTKTGIHASAVLKDPQTYEHIAPEAVGNHRKVLVSDQAGRSNVIAELERAGIPFDKNDP 360 Query: 361 RLTRLVEELKEREAAGFAYESANASFDLLARRTLGKVPEYFKVEQFDVNVEQRYNANGQR 420 +LTRLVEE+KE+EAAG+AYESANASFDLLARRTLGKVP+YFKV QFDVNVEQRYNA QR Sbjct: 361 KLTRLVEEMKEKEAAGYAYESANASFDLLARRTLGKVPDYFKVVQFDVNVEQRYNALAQR 420 Query: 421 VTVALAVVKVDVDGERLISAAEGNGPVNALDVALRKDLGKYQKYIDGLKLIDYRVRILNG 480 VTVA+AVVKVDV GE LISAAEGNGPVNALDVALRKDLGKYQKYI+GLKL+DYRVRILNG Sbjct: 421 VTVAMAVVKVDVAGETLISAAEGNGPVNALDVALRKDLGKYQKYIEGLKLVDYRVRILNG 480 Query: 481 GTEAVTRVLIESEDETGESWTTVGVSPNIIDASFQALMDSVFYKLVKSGAQA 532 GTEAVTRVLIESEDE GE WTTVGVSPNIIDASFQALMDSV YKLVKS A A Sbjct: 481 GTEAVTRVLIESEDEGGERWTTVGVSPNIIDASFQALMDSVVYKLVKSNAPA 532 >ref|YP_001239500.1| putative alpha-isopropylmalate/homocitrate synthase family transferase [Bradyrhizobium sp. BTAi1] gb|ABQ35594.1| 2-isopropylmalate synthase [Bradyrhizobium sp. BTAi1] Length = 537 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/528 (86%), Positives = 491/528 (92%) Query: 3 RERLYLFDTTLRDGAQTNGVDFTLQDKQVISGMLDALGIDYVEGGYPGANPTDSEFFSRK 62 RERLYLFDTTLRDGAQTNGVDFTL DK+VI+ MLD LGIDYVEGGYPGANP D+EFF+ K Sbjct: 8 RERLYLFDTTLRDGAQTNGVDFTLADKRVIARMLDELGIDYVEGGYPGANPLDTEFFAEK 67 Query: 63 PDFEHARFTAFGMTRRPGRSASNDPGLAGILEAKADAICFVAKSSAYQVRVALETTNEEN 122 P ARFTAFGMTRR GRS SNDPG+A +LEAKADAICFVAKSSAYQVRVALETTNEEN Sbjct: 68 PRLGQARFTAFGMTRRAGRSVSNDPGVAALLEAKADAICFVAKSSAYQVRVALETTNEEN 127 Query: 123 LASIRDSVAAAKALGREVMVDCEHFFDGYKENRDYALACAKAAYQSGARWVVLCDTNGGT 182 LASIRDSV AA+A GREVM+DCEHFFDGYKEN ++ALACA+ AY++GARWVVLCDTNGGT Sbjct: 128 LASIRDSVTAARAAGREVMLDCEHFFDGYKENAEFALACARTAYEAGARWVVLCDTNGGT 187 Query: 183 MPHEIETIVGDVVKHVPGAYLGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERCGN 242 MPHEIETIVG V KHVPG +LGIHAHNDTEQAVANSLAAVRAG RQIQGTLNGLGERCGN Sbjct: 188 MPHEIETIVGVVAKHVPGDHLGIHAHNDTEQAVANSLAAVRAGVRQIQGTLNGLGERCGN 247 Query: 243 ANLCSLIPTLKLKQEFSDKFEIGVTTEKLATLMKVSRTLDDMLNRAPNRHAAYVGESAFV 302 ANLCSLIPTLKLK EFS +FEIGV+ ++L +L+KVSRTLDDMLNRAPNRHA YVGESAFV Sbjct: 248 ANLCSLIPTLKLKGEFSSRFEIGVSDQQLGSLVKVSRTLDDMLNRAPNRHAPYVGESAFV 307 Query: 303 TKTGIHASAVMKDPQTYEHVLPELVGNHRKVLVSDQAGRSNVMAELDRAGIAYDKSDPRL 362 TKTGIHASAV+KDPQTYEHV PE VGNHRKVLVSDQAGRSNV+A L+R GI + K+DP+L Sbjct: 308 TKTGIHASAVLKDPQTYEHVAPESVGNHRKVLVSDQAGRSNVIAALERGGIPFSKNDPKL 367 Query: 363 TRLVEELKEREAAGFAYESANASFDLLARRTLGKVPEYFKVEQFDVNVEQRYNANGQRVT 422 TRLVEELKEREAAG+AYESANASF+LLARRTLG VPE+F+VEQFDVNVEQRYNA G+R+T Sbjct: 368 TRLVEELKEREAAGYAYESANASFELLARRTLGSVPEFFRVEQFDVNVEQRYNAVGERIT 427 Query: 423 VALAVVKVDVDGERLISAAEGNGPVNALDVALRKDLGKYQKYIDGLKLIDYRVRILNGGT 482 VALAVVKVDV GERLISAAEGNGPVNALDVALRKDLGKYQ YIDGLKLIDYRVRILNGGT Sbjct: 428 VALAVVKVDVAGERLISAAEGNGPVNALDVALRKDLGKYQGYIDGLKLIDYRVRILNGGT 487 Query: 483 EAVTRVLIESEDETGESWTTVGVSPNIIDASFQALMDSVFYKLVKSGA 530 EAVTRVLIESEDETGE WTTVGVSPNII ASFQALMDSVFYKLVKSGA Sbjct: 488 EAVTRVLIESEDETGERWTTVGVSPNIIAASFQALMDSVFYKLVKSGA 535 >ref|YP_531962.1| putative alpha-isopropylmalate/homocitrate synthase family transferase [Rhodopseudomonas palustris BisB18] gb|ABD87643.1| 2-isopropylmalate synthase [Rhodopseudomonas palustris BisB18] Length = 532 Score = 922 bits (2384), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/532 (83%), Positives = 486/532 (91%) Query: 1 VSRERLYLFDTTLRDGAQTNGVDFTLQDKQVISGMLDALGIDYVEGGYPGANPTDSEFFS 60 +SRERLYLFDTTLRDGAQTNGVDFTL DK++I+ MLD LGIDYVEGGYPGANP+D+EFF+ Sbjct: 1 MSRERLYLFDTTLRDGAQTNGVDFTLHDKRLIAAMLDDLGIDYVEGGYPGANPSDTEFFA 60 Query: 61 RKPDFEHARFTAFGMTRRPGRSASNDPGLAGILEAKADAICFVAKSSAYQVRVALETTNE 120 P + A FTAFGMTRRPGRSASNDPG+A +LEAKADAICFVAKSSAYQVRVAL TTNE Sbjct: 61 TDPALKSATFTAFGMTRRPGRSASNDPGIAALLEAKADAICFVAKSSAYQVRVALGTTNE 120 Query: 121 ENLASIRDSVAAAKALGREVMVDCEHFFDGYKENRDYALACAKAAYQSGARWVVLCDTNG 180 ENLASIRDSV AAKA GREV+VDCEHFFDGYKE+ +AL+CAKAAY +GARWVVLCDTNG Sbjct: 121 ENLASIRDSVGAAKARGREVLVDCEHFFDGYKEDPQFALSCAKAAYDAGARWVVLCDTNG 180 Query: 181 GTMPHEIETIVGDVVKHVPGAYLGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERC 240 GTMPHEIE IVG VVK +PG+++GIHAHNDTEQAVA SLAAVRAGARQIQGTLNGLGERC Sbjct: 181 GTMPHEIEAIVGQVVKQIPGSHVGIHAHNDTEQAVACSLAAVRAGARQIQGTLNGLGERC 240 Query: 241 GNANLCSLIPTLKLKQEFSDKFEIGVTTEKLATLMKVSRTLDDMLNRAPNRHAAYVGESA 300 GNANLCS+IPTLKLK EF++ F+IGV+ +KLATL++VSR LD++LNR N HAAYVG SA Sbjct: 241 GNANLCSMIPTLKLKPEFAEAFDIGVSEDKLATLVQVSRALDNILNRPSNPHAAYVGGSA 300 Query: 301 FVTKTGIHASAVMKDPQTYEHVLPELVGNHRKVLVSDQAGRSNVMAELDRAGIAYDKSDP 360 FVTKTGIHASAVMKDP TYEHV PE VGNHRKVLVSDQAGRSNV+A L R I +DK DP Sbjct: 301 FVTKTGIHASAVMKDPHTYEHVSPETVGNHRKVLVSDQAGRSNVLAALSRTTIPFDKDDP 360 Query: 361 RLTRLVEELKEREAAGFAYESANASFDLLARRTLGKVPEYFKVEQFDVNVEQRYNANGQR 420 +L RLVEELKEREAAG+AYESANASFDLLARRTLGKVPE+F+VEQFDVNVEQRYN++G R Sbjct: 361 KLNRLVEELKEREAAGYAYESANASFDLLARRTLGKVPEFFRVEQFDVNVEQRYNSHGNR 420 Query: 421 VTVALAVVKVDVDGERLISAAEGNGPVNALDVALRKDLGKYQKYIDGLKLIDYRVRILNG 480 VT+A+AVVKV+VDGE LISAA+GNGPVNALDVALRKDLGK+QKYI+ LKLIDYRVRILNG Sbjct: 421 VTMAMAVVKVNVDGEVLISAADGNGPVNALDVALRKDLGKFQKYIENLKLIDYRVRILNG 480 Query: 481 GTEAVTRVLIESEDETGESWTTVGVSPNIIDASFQALMDSVFYKLVKSGAQA 532 GTEAVTRVLIESEDE GE WTT+GVSPNIIDASFQALMDSV YKLVK AQA Sbjct: 481 GTEAVTRVLIESEDEQGERWTTIGVSPNIIDASFQALMDSVVYKLVKCNAQA 532