BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0175.0006.p (530 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_767221.1| bifunctional phosphoribosylaminoimidazolecarbox... 940 0.0 ref|NP_945384.1| bifunctional phosphoribosylaminoimidazolecarbox... 907 0.0 ref|YP_001989067.1| bifunctional phosphoribosylaminoimidazolecar... 907 0.0 ref|YP_316778.1| bifunctional phosphoribosylaminoimidazolecarbox... 903 0.0 ref|YP_575556.1| bifunctional phosphoribosylaminoimidazolecarbox... 899 0.0 >ref|NP_767221.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bradyrhizobium japonicum USDA 110] sp|Q89WU7.1|PUR9_BRAJA RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase dbj|BAC45846.1| bifunctional purine biosynthesis protein [Bradyrhizobium japonicum USDA 110] Length = 530 Score = 940 bits (2429), Expect = 0.0, Method: Compositional matrix adjust. Identities = 472/530 (89%), Positives = 497/530 (93%) Query: 1 MTEQLRRVTRALLSVSDKTGLIDFAKALADQGVELVSTGGTAKAIAAAGLKVRDVSELTG 60 MT+ RRVTRALLSVSDKTGLI+FAKALA VELVSTGGTAKAIAAAGLKV+DVSELTG Sbjct: 1 MTDHPRRVTRALLSVSDKTGLIEFAKALAAHDVELVSTGGTAKAIAAAGLKVKDVSELTG 60 Query: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNKEHAAAMASHGIAPIDLLVVNLYPFEATVDKGAG 120 FPEMMDGRVKTLHPKVHGGLLAIRDNK+HA AM +HGIAPIDLLVVNLYPFEATVDKGAG Sbjct: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNKDHADAMKAHGIAPIDLLVVNLYPFEATVDKGAG 120 Query: 121 FEECIENIDIGGPAMIRAAAKNHDDVAVVVEANDYSAVLDELAAHKGATSLQLRRRLAAK 180 FE+CIENIDIGGPAMIRAAAKNHDDVAVVVEA DY AVLDELAA+KGAT+L+LRRRLAAK Sbjct: 121 FEDCIENIDIGGPAMIRAAAKNHDDVAVVVEAEDYKAVLDELAANKGATTLKLRRRLAAK 180 Query: 181 AYARTAAYDAAISNWFAVQLDTKAPDFRAFGGKLIQSLRYGENPHQTAAFYATPEKRPGV 240 AYARTAAYDAAISNWF QL+ APDFRAFGGKLIQSLRYGENPHQTAAFYATP+KRPGV Sbjct: 181 AYARTAAYDAAISNWFNRQLEIDAPDFRAFGGKLIQSLRYGENPHQTAAFYATPDKRPGV 240 Query: 241 ATARQLQGKELSYNNINDTDAAYECVGEFDPQRTAACVIVKHANPCGVAEGPDLATAYAR 300 +TARQLQGKELSYNNINDTDAAYEC+GEFD +RTAACVIVKHANPCGVAEG DL +AY + Sbjct: 241 STARQLQGKELSYNNINDTDAAYECIGEFDAKRTAACVIVKHANPCGVAEGSDLVSAYRK 300 Query: 301 ALACDSTSAYGGIIAVNRTLDADAARAIIGIFTEVIIAPDATEEAISIIAGRRNLRLLLA 360 ALACDSTSA+GGIIA+NR LDAD AR I IFTEVIIAPDA+EEAI+II R+NLRLLLA Sbjct: 301 ALACDSTSAFGGIIAMNRALDADTAREITKIFTEVIIAPDASEEAIAIIGARKNLRLLLA 360 Query: 361 GGLPNARATGLTAKTVAGGLLVQSRDNAVVEDMNLKVATKRAPTDAELRDLKFAFRVAKH 420 G LP+ RA GLTAKTVAGGLLVQSRDNAVV+DM KV TKRAPTDAE+RDLKFAFRVAKH Sbjct: 361 GSLPDPRAPGLTAKTVAGGLLVQSRDNAVVDDMTFKVVTKRAPTDAEMRDLKFAFRVAKH 420 Query: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKALDAAAELKLAEPLTKGSVVASDAFF 480 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKA DAA ELKLAEPLTKGSVVASDAFF Sbjct: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKAQDAAVELKLAEPLTKGSVVASDAFF 480 Query: 481 PFADGMLACIEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH 530 PFADGMLACIEAGATAV+QPGGSMRDDEVIKAADEHGIAMVFTG RHFRH Sbjct: 481 PFADGMLACIEAGATAVVQPGGSMRDDEVIKAADEHGIAMVFTGTRHFRH 530 >ref|NP_945384.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodopseudomonas palustris CGA009] emb|CAE25472.1| bifunctional purine biosynthesis protein [Rhodopseudomonas palustris CGA009] Length = 530 Score = 907 bits (2345), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/530 (86%), Positives = 487/530 (91%) Query: 1 MTEQLRRVTRALLSVSDKTGLIDFAKALADQGVELVSTGGTAKAIAAAGLKVRDVSELTG 60 MT+ RRVTRALLSVSDKTGLIDFA+ALA GVELVSTGGTAKAIAAAGL V+DVSELTG Sbjct: 1 MTQNSRRVTRALLSVSDKTGLIDFARALAGHGVELVSTGGTAKAIAAAGLPVKDVSELTG 60 Query: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNKEHAAAMASHGIAPIDLLVVNLYPFEATVDKGAG 120 FPEMMDGRVKTLHPKVHGGLLAIRDN EH AMA+HGI IDLLVVNLYPFEATVDKGA Sbjct: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNDEHTQAMAAHGIPQIDLLVVNLYPFEATVDKGAS 120 Query: 121 FEECIENIDIGGPAMIRAAAKNHDDVAVVVEANDYSAVLDELAAHKGATSLQLRRRLAAK 180 +E+CIENIDIGGPAMIRAAAKNHDDVAVVVEA+DY AVLDEL A+ GAT+L LR+RLAAK Sbjct: 121 YEDCIENIDIGGPAMIRAAAKNHDDVAVVVEASDYQAVLDELTANNGATTLPLRKRLAAK 180 Query: 181 AYARTAAYDAAISNWFAVQLDTKAPDFRAFGGKLIQSLRYGENPHQTAAFYATPEKRPGV 240 AYARTAAYDAAISNWFA+QL T APDFRA GG+LIQSLRYGENPHQTAAFYATPEKRPGV Sbjct: 181 AYARTAAYDAAISNWFALQLKTDAPDFRAIGGRLIQSLRYGENPHQTAAFYATPEKRPGV 240 Query: 241 ATARQLQGKELSYNNINDTDAAYECVGEFDPQRTAACVIVKHANPCGVAEGPDLATAYAR 300 ATARQ+QGKELSYNNINDTDAAYECVGEFD RTAACVIVKHANPCGVAEG L AY + Sbjct: 241 ATARQVQGKELSYNNINDTDAAYECVGEFDAARTAACVIVKHANPCGVAEGSSLLDAYKK 300 Query: 301 ALACDSTSAYGGIIAVNRTLDADAARAIIGIFTEVIIAPDATEEAISIIAGRRNLRLLLA 360 ALACDS SA+GGI+A+NRTLDA+AARAI IFTEVIIAPDAT+EAI+I+A ++NLRLLLA Sbjct: 301 ALACDSVSAFGGIVALNRTLDAEAARAITEIFTEVIIAPDATDEAIAIVAAKKNLRLLLA 360 Query: 361 GGLPNARATGLTAKTVAGGLLVQSRDNAVVEDMNLKVATKRAPTDAELRDLKFAFRVAKH 420 G LP+ RA GLT KTVAGGLLVQSRDNAVV+DM LKV TKR PT+AELRDLKFAFRV KH Sbjct: 361 GALPDPRANGLTYKTVAGGLLVQSRDNAVVDDMALKVVTKRQPTEAELRDLKFAFRVGKH 420 Query: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKALDAAAELKLAEPLTKGSVVASDAFF 480 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKA DAA +KLA P+TKGSVVASDAFF Sbjct: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKAQDAAEAMKLAAPMTKGSVVASDAFF 480 Query: 481 PFADGMLACIEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH 530 PFADGMLACIEAGATAVIQPGGS+RDDEVIKAAD+ GIAMVFTG RHFRH Sbjct: 481 PFADGMLACIEAGATAVIQPGGSVRDDEVIKAADDAGIAMVFTGTRHFRH 530 >ref|YP_001989067.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodopseudomonas palustris TIE-1] gb|ACE98591.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodopseudomonas palustris TIE-1] Length = 530 Score = 907 bits (2344), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/530 (86%), Positives = 487/530 (91%) Query: 1 MTEQLRRVTRALLSVSDKTGLIDFAKALADQGVELVSTGGTAKAIAAAGLKVRDVSELTG 60 MT+ RRVTRALLSVSDKTGLIDFA+ALA GVELVSTGGTAKAIAAAGL V+DVSELTG Sbjct: 1 MTQNPRRVTRALLSVSDKTGLIDFARALAGHGVELVSTGGTAKAIAAAGLPVKDVSELTG 60 Query: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNKEHAAAMASHGIAPIDLLVVNLYPFEATVDKGAG 120 FPEMMDGRVKTLHPKVHGGLLAIRDN EH AMA+HGI IDLLVVNLYPFEATVDKGA Sbjct: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNDEHTQAMAAHGIPQIDLLVVNLYPFEATVDKGAS 120 Query: 121 FEECIENIDIGGPAMIRAAAKNHDDVAVVVEANDYSAVLDELAAHKGATSLQLRRRLAAK 180 +E+CIENIDIGGPAMIRAAAKNHDDVAVVVEA+DY AVLDEL A+ GAT+L LR+RLAAK Sbjct: 121 YEDCIENIDIGGPAMIRAAAKNHDDVAVVVEASDYQAVLDELTANNGATTLPLRKRLAAK 180 Query: 181 AYARTAAYDAAISNWFAVQLDTKAPDFRAFGGKLIQSLRYGENPHQTAAFYATPEKRPGV 240 AYARTAAYDAAISNWFA+QL T APDFRA GG+LIQSLRYGENPHQTAAFYATPEKRPGV Sbjct: 181 AYARTAAYDAAISNWFALQLKTDAPDFRAIGGRLIQSLRYGENPHQTAAFYATPEKRPGV 240 Query: 241 ATARQLQGKELSYNNINDTDAAYECVGEFDPQRTAACVIVKHANPCGVAEGPDLATAYAR 300 ATARQ+QGKELSYNNINDTDAAYECVGEFD RTAACVIVKHANPCGVAEG L AY + Sbjct: 241 ATARQVQGKELSYNNINDTDAAYECVGEFDAARTAACVIVKHANPCGVAEGSSLLDAYKK 300 Query: 301 ALACDSTSAYGGIIAVNRTLDADAARAIIGIFTEVIIAPDATEEAISIIAGRRNLRLLLA 360 ALACDS SA+GGI+A+NRTLDA+AARAI IFTEVIIAPDAT+EAI+I+A ++NLRLLLA Sbjct: 301 ALACDSVSAFGGIVALNRTLDAEAARAITEIFTEVIIAPDATDEAIAIVAAKKNLRLLLA 360 Query: 361 GGLPNARATGLTAKTVAGGLLVQSRDNAVVEDMNLKVATKRAPTDAELRDLKFAFRVAKH 420 G LP+ RA GLT KTVAGGLLVQSRDNAVV+DM LKV TKR PT+AELRDLKFAFRV KH Sbjct: 361 GALPDPRANGLTYKTVAGGLLVQSRDNAVVDDMALKVVTKRQPTEAELRDLKFAFRVGKH 420 Query: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKALDAAAELKLAEPLTKGSVVASDAFF 480 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKA DAA +KLA P+TKGSVVASDAFF Sbjct: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKAQDAAEAMKLAAPMTKGSVVASDAFF 480 Query: 481 PFADGMLACIEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH 530 PFADGMLACIEAGATAVIQPGGS+RDDEVIKAAD+ GIAMVFTG RHFRH Sbjct: 481 PFADGMLACIEAGATAVIQPGGSVRDDEVIKAADDAGIAMVFTGTRHFRH 530 >ref|YP_316778.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Nitrobacter winogradskyi Nb-255] gb|ABA03426.1| IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase [Nitrobacter winogradskyi Nb-255] Length = 530 Score = 903 bits (2333), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/530 (85%), Positives = 486/530 (91%) Query: 1 MTEQLRRVTRALLSVSDKTGLIDFAKALADQGVELVSTGGTAKAIAAAGLKVRDVSELTG 60 MT++ RRVTRALLSVSDKTGL +FA+ALAD GVELVSTGGTAK IAAAGLKV DVS+LTG Sbjct: 1 MTDRPRRVTRALLSVSDKTGLTEFARALADLGVELVSTGGTAKEIAAAGLKVSDVSDLTG 60 Query: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNKEHAAAMASHGIAPIDLLVVNLYPFEATVDKGAG 120 FPEMMDGRVKTLHPKVHGGLLAIRDN +HA +M HGIAPIDLLVVNLYPFE+TVDKGA Sbjct: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNADHAKSMKDHGIAPIDLLVVNLYPFESTVDKGAA 120 Query: 121 FEECIENIDIGGPAMIRAAAKNHDDVAVVVEANDYSAVLDELAAHKGATSLQLRRRLAAK 180 EECIENIDIGGPAMIRAAAKNHDDVAVVVE DY AVLDEL A+ GAT+L LR+RLAAK Sbjct: 121 CEECIENIDIGGPAMIRAAAKNHDDVAVVVEPQDYQAVLDELKANAGATTLSLRKRLAAK 180 Query: 181 AYARTAAYDAAISNWFAVQLDTKAPDFRAFGGKLIQSLRYGENPHQTAAFYATPEKRPGV 240 AYARTAAYDAAISNWFAVQL+T APD+RA GG+L Q LRYGENPHQTAAFY TPE+R GV Sbjct: 181 AYARTAAYDAAISNWFAVQLETDAPDYRAVGGRLAQRLRYGENPHQTAAFYRTPERRAGV 240 Query: 241 ATARQLQGKELSYNNINDTDAAYECVGEFDPQRTAACVIVKHANPCGVAEGPDLATAYAR 300 ATARQLQGKELSYNNINDTDAAYECV EFD RTAACVI+KHANPCGVAEG L AY R Sbjct: 241 ATARQLQGKELSYNNINDTDAAYECVAEFDAARTAACVIIKHANPCGVAEGSSLTEAYRR 300 Query: 301 ALACDSTSAYGGIIAVNRTLDADAARAIIGIFTEVIIAPDATEEAISIIAGRRNLRLLLA 360 ALACD TSAYGGIIA NRT+DADAA A+ GIFTEVIIAPDATEEAI++I R+NLRLLLA Sbjct: 301 ALACDQTSAYGGIIAFNRTIDADAANAVAGIFTEVIIAPDATEEAIAVIGKRKNLRLLLA 360 Query: 361 GGLPNARATGLTAKTVAGGLLVQSRDNAVVEDMNLKVATKRAPTDAELRDLKFAFRVAKH 420 GGLP+ RA GLTAKTVAGGLLVQ RDNAV++DM+LKV TKR PT+AE+RDL+FAFRVAKH Sbjct: 361 GGLPDPRARGLTAKTVAGGLLVQGRDNAVIDDMSLKVVTKRPPTEAEMRDLRFAFRVAKH 420 Query: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKALDAAAELKLAEPLTKGSVVASDAFF 480 VKSNTI+YA+DLATVGIGAGQMSRVDSARIAARKA DAA +LKLAEPLTKGSVVASDAFF Sbjct: 421 VKSNTIVYARDLATVGIGAGQMSRVDSARIAARKAEDAARDLKLAEPLTKGSVVASDAFF 480 Query: 481 PFADGMLACIEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH 530 PFADGMLACI+AGATAVIQPGGSMRD+EVIKAADEHGIAMVFTGVRHFRH Sbjct: 481 PFADGMLACIKAGATAVIQPGGSMRDEEVIKAADEHGIAMVFTGVRHFRH 530 >ref|YP_575556.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Nitrobacter hamburgensis X14] gb|ABE61096.1| IMP cyclohydrolase [Nitrobacter hamburgensis X14] Length = 530 Score = 899 bits (2323), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/530 (86%), Positives = 492/530 (92%) Query: 1 MTEQLRRVTRALLSVSDKTGLIDFAKALADQGVELVSTGGTAKAIAAAGLKVRDVSELTG 60 MT++ RRVTRALLSVSDKTGLI+FA+ALA G++LVSTGGTAKAIAAAGLKV DVSELTG Sbjct: 1 MTDRPRRVTRALLSVSDKTGLIEFARALAGLGIDLVSTGGTAKAIAAAGLKVSDVSELTG 60 Query: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNKEHAAAMASHGIAPIDLLVVNLYPFEATVDKGAG 120 FPEMMDGRVKTLHPKVHGGLLAIRDN +HA AM HGIAPIDLLVVNLYPFEATVDKGA Sbjct: 61 FPEMMDGRVKTLHPKVHGGLLAIRDNGDHAKAMKDHGIAPIDLLVVNLYPFEATVDKGAP 120 Query: 121 FEECIENIDIGGPAMIRAAAKNHDDVAVVVEANDYSAVLDELAAHKGATSLQLRRRLAAK 180 +E+CIENIDIGGPAMIRAAAKNHDDVAVVVEA DY AVLDEL A+ GAT+L LR+RLAAK Sbjct: 121 YEDCIENIDIGGPAMIRAAAKNHDDVAVVVEAQDYQAVLDELKANDGATTLGLRKRLAAK 180 Query: 181 AYARTAAYDAAISNWFAVQLDTKAPDFRAFGGKLIQSLRYGENPHQTAAFYATPEKRPGV 240 AYARTAAYDAAISNWFAVQL T APD+RAFGG+L Q+LRYGENPHQTAAFY TP++R GV Sbjct: 181 AYARTAAYDAAISNWFAVQLATDAPDYRAFGGRLAQTLRYGENPHQTAAFYRTPDRRAGV 240 Query: 241 ATARQLQGKELSYNNINDTDAAYECVGEFDPQRTAACVIVKHANPCGVAEGPDLATAYAR 300 +TARQLQGKELSYNNINDTDAAYECV EFD RTAACVI+KHANPCGVAEG DLA+AY + Sbjct: 241 STARQLQGKELSYNNINDTDAAYECVAEFDATRTAACVIIKHANPCGVAEGADLASAYRK 300 Query: 301 ALACDSTSAYGGIIAVNRTLDADAARAIIGIFTEVIIAPDATEEAISIIAGRRNLRLLLA 360 ALACD TSAYGGIIA NRTLDADAA A+ GIFTEVIIAPDATEEAI+II R+NLRLLLA Sbjct: 301 ALACDQTSAYGGIIAFNRTLDADAANAVAGIFTEVIIAPDATEEAIAIIGKRKNLRLLLA 360 Query: 361 GGLPNARATGLTAKTVAGGLLVQSRDNAVVEDMNLKVATKRAPTDAELRDLKFAFRVAKH 420 GGLP+ RA GLTAKTVAGGLLVQ RDNAVV+DM L VATKRAPTDAE+RDL+FAFR+AKH Sbjct: 361 GGLPDPRARGLTAKTVAGGLLVQGRDNAVVDDMALTVATKRAPTDAEMRDLRFAFRIAKH 420 Query: 421 VKSNTIIYAKDLATVGIGAGQMSRVDSARIAARKALDAAAELKLAEPLTKGSVVASDAFF 480 VKSNTI+YAKDLATVGIGAGQMSRVDSARIAARKA DAA ELKLA+PLT GSVVASDAFF Sbjct: 421 VKSNTIVYAKDLATVGIGAGQMSRVDSARIAARKADDAARELKLAQPLTIGSVVASDAFF 480 Query: 481 PFADGMLACIEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH 530 PFADGMLAC+EAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH Sbjct: 481 PFADGMLACVEAGATAVIQPGGSMRDDEVIKAADEHGIAMVFTGVRHFRH 530