BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0156.0076.p (500 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001242751.1| diguanylate cyclase [Bradyrhizobium sp. BTAi... 389 e-106 ref|YP_001894059.1| diguanylate cyclase [Burkholderia phytofirma... 387 e-105 ref|YP_004633952.1| diguanylate cyclase [Oligotropha carboxidovo... 384 e-104 ref|YP_372356.1| diguanylate cyclase [Burkholderia sp. 383] >gi|... 384 e-104 ref|YP_002287933.1| diguanylate cyclase [Oligotropha carboxidovo... 384 e-104 >ref|YP_001242751.1| diguanylate cyclase [Bradyrhizobium sp. BTAi1] gb|ABQ38845.1| diguanylate cyclase [Bradyrhizobium sp. BTAi1] Length = 502 Score = 389 bits (999), Expect = e-106, Method: Compositional matrix adjust. Identities = 207/488 (42%), Positives = 301/488 (61%), Gaps = 3/488 (0%) Query: 2 NGLLPKPKAVPTKRLLALGIGLVLCFSAICASILWEMASKDYRHAKEGATNLVASIASEI 61 G +P + + L++ I ++ FSAICAS++ ++ + A++ N+ ASIA++I Sbjct: 7 TGRAKQPWRLSARTLISCSISTIIGFSAICASVMVDLRRGEEVRARQALENMAASIAADI 66 Query: 62 DRNIDLYDLSLQAVADGVKLPELGKISPELRQVVLFDRAATAKDLGSILVLNAAGDVTLD 121 RN++LYDLSL+AVA + LPE+ ++S LRQ++LFDRA+TA++ G+I V +A G + +D Sbjct: 67 SRNVELYDLSLRAVAGNLLLPEIHEVSKPLRQLILFDRASTARNFGTIQVFDAQGRLIID 126 Query: 122 SRTLTPRTANFADRDFFRAHQTRADSGLFISAPWITSDGEYLISLSRRINNDDGSFAGVV 181 S TL PR + +D DFF+ H+ R D+GL++ P G I LSRRI+ DG FAGVV Sbjct: 127 SATLDPRPEDRSDADFFQVHRDRPDAGLYVGRP-AQHHGPSSIVLSRRISTPDGRFAGVV 185 Query: 182 AGSMRLSYFHNLFRKLNFGFGDSMALFNSDGVILMRAPFDISKIGQSIKDSLVFKQFPAR 241 AGS+RLSYF +LF L G GDS+ +F DG +++ APFD IG+++ + + Sbjct: 186 AGSLRLSYFRDLFGSLTLGPGDSITVFRRDGTLIVSAPFDPDAIGRNLARAPAVTRALTE 245 Query: 242 QSGSYITKSIVDHVSRLYVFQAVGHNRLLIAEGLALDGIYADWWQQLWLIGSVVAALCGF 301 +G + +D + RL V++ G L++ + +YA W + IG+++ AL F Sbjct: 246 PTGWSSSYGALDDLPRLLVWRN-GTEPLVVVASKTWESVYAYWRHEAMQIGAMMLALIVF 304 Query: 302 SIVLMFYLVAALKRRAAAEDRLAHLASTDALTGLANRRRLDDTLDVEWRRGMRAKAPVSL 361 + ++ R E RL LA+TD LTGL NRR+ D+T++VEWRR +R AP+ L Sbjct: 305 VLAATQVAAREIQLRTKVETRLEQLATTDPLTGLKNRRKFDETIEVEWRRALRHHAPLGL 364 Query: 362 LMIDVDHFKIYNDTYGHQAGDAVLTTVGRCIASSAKRATDLGARYGGEEFSVLLPGIGKT 421 LMID DHFK YND +GHQAGD VL + CI+ S +RA D ARYGGEEF+VLLPG Sbjct: 365 LMIDADHFKSYNDNHGHQAGDQVLVGIAVCISDSVRRAGDCAARYGGEEFAVLLPGTSDA 424 Query: 422 GALEIAERIRAKLAAARESEPELPTVSIGLSCLVPDHERTSRDLLKAADLALYQAKREGR 481 AL +AE IR K+A E +VSIG++ + P + L+ AAD ALY AK GR Sbjct: 425 DALHVAETIRTKVAIW-AGEAGNTSVSIGVASITPSRDTDWTALMNAADRALYMAKAAGR 483 Query: 482 DRVIVSPI 489 +R + + + Sbjct: 484 NRCVAATV 491 >ref|YP_001894059.1| diguanylate cyclase [Burkholderia phytofirmans PsJN] gb|ACD14835.1| diguanylate cyclase [Burkholderia phytofirmans PsJN] Length = 516 Score = 387 bits (993), Expect = e-105, Method: Compositional matrix adjust. Identities = 214/486 (44%), Positives = 300/486 (61%), Gaps = 9/486 (1%) Query: 9 KAVPTKR---LLALGIGLVLCFSAICASILWEMASKDYRHAKEGATNLVASIASEIDRNI 65 KA+ T+R ++A+ I L AI +L +M R A++ N+ + ++ RN+ Sbjct: 5 KAMVTRRPNIVIAISIVLASAILAIAVWVLAQMRDDALRRAQDSVFNVSLLVERDVSRNL 64 Query: 66 DLYDLSLQAVADGVKLPELGKISPELRQVVLFDRAATAKDLGSILVLNAAGDVTLDSRTL 125 ++YDLSL+AV DG+K P + ++ P +RQ+VLFD +A+AKD+GSILV + AG++ DS+ Sbjct: 65 EIYDLSLRAVIDGLKQPGVLELDPAIRQMVLFDGSASAKDMGSILVTDEAGNIKFDSQAT 124 Query: 126 TPRTANFADRDFFRAHQTRADSGLFISAPWI--TSDGEYLISLSRRINNDDGSFAGVVAG 183 PR N +DRD+F+ + + GL+IS P++ S E I++SRRI DGSF GVV G Sbjct: 125 PPRRVNLSDRDYFKVQRDSTNVGLYISHPFVPKVSGKEISIAMSRRITRPDGSFGGVVVG 184 Query: 184 SMRLSYFHNLFRKLNFGFGDSMALFNSDGVILMRAPFDISKIGQSIKDSLVFKQFPARQS 243 +MRL+YF LF +N G G SMAL SDG +LMR PFD IG ++ + + +F + S Sbjct: 185 TMRLTYFRRLFAGMNLGAGGSMALMLSDGTMLMRRPFDPKIIGINLTGTANYSRFTQQPS 244 Query: 244 GSYITKSIVDHVSRLYVFQAVGHNRLLIAEGLALDGIYADWWQQLWLIGSVVAALCGFSI 303 G + + +D V R Y F+ + L++ L+ IY +W + W+IGS++AAL I Sbjct: 245 GDFFGTAAIDGVERWYAFRHIDMYPLILDVALSTRDIYVEWRHRAWIIGSLIAALDVTII 304 Query: 304 VLMFYLVAALKRRAAAEDRLAHLASTDALTGLANRRRLDDTLDVEWRRGMRAKAPVSLLM 363 L L+ R AAE+ L LA TD LTGL NRR ++ + EWRR R P+S+L+ Sbjct: 305 ALAVLFSYQLRYRRAAEEELRVLARTDGLTGLNNRRTFEEHAEDEWRRAQRNAWPLSMLL 364 Query: 364 IDVDHFKIYNDTYGHQAGDAVLTTVGRCIASSAKRATDLGARYGGEEFSVLLPGIGKTGA 423 IDVD FK +ND YGH AGD LT V RCI+ S +R D ARYGGEEF+VLLP +TGA Sbjct: 365 IDVDSFKGFNDLYGHSAGDDALTAVARCISQSVRRPGDTAARYGGEEFAVLLPDTDETGA 424 Query: 424 LEIAERIRAKLAAAR----ESEPELPTVSIGLSCLVPDHERTSRDLLKAADLALYQAKRE 479 IAE+IRA + A + S + TVSIG++ + TSR LL AAD ALY+AK Sbjct: 425 AFIAEKIRAAVQALQLRHVASSQHVLTVSIGIATTRGEAFATSRALLNAADDALYEAKDA 484 Query: 480 GRDRVI 485 GR+RV+ Sbjct: 485 GRNRVL 490 >ref|YP_004633952.1| diguanylate cyclase [Oligotropha carboxidovorans OM5] gb|AEI04081.1| diguanylate cyclase [Oligotropha carboxidovorans OM4] gb|AEI07711.1| diguanylate cyclase [Oligotropha carboxidovorans OM5] Length = 489 Score = 384 bits (987), Expect = e-104, Method: Compositional matrix adjust. Identities = 208/473 (43%), Positives = 298/473 (63%), Gaps = 11/473 (2%) Query: 23 LVLC------FSAICASILWEMASKDYRHAKEGATNLVASIASEIDRNIDLYDLSLQAVA 76 +VLC F IC S+L E A+ + NL A+I S+I R+I++YDLSL+ Sbjct: 14 VVLCALTTSAFLLICGSVLLETRRAAGELARSASANLAATIDSDIVRSIEVYDLSLRNAV 73 Query: 77 DGVKLPELGKISPELRQVVLFDRAATAKDLGSILVLNAAGDVTLDSRTLTPRTANFADRD 136 + + + +IS + ++LFD AATA+ G I + + G + LDS TL P + AD++ Sbjct: 74 NNMLTLDTERISLPILHLILFDHAATAQHYGRIRIFDETGKLKLDSSTLHPAQESCADKE 133 Query: 137 FFRAHQTRADSGLFISAPWITSDGEYLISLSRRINNDDGSFAGVVAGSMRLSYFHNLFRK 196 FF+ H+ +D+GL++S P + + L+ LSRRI DG F GVV GS+R SYF +LF Sbjct: 134 FFKIHRASSDAGLYVSDPEVGTGAPALV-LSRRITGHDGRFLGVVVGSIRYSYFRDLFSH 192 Query: 197 LNFGFGDSMALFNSDGVILMRAPFDISKIGQSIKDSLVFKQFPARQSGSYITKSIVDHVS 256 L FG GD+ +F +DG ++MR P + IG+ + +S +Q A +SGS +S +D++ Sbjct: 193 LKFGEGDTATVFRNDGRVMMRQPSNSDTIGKDLSNSAGVRQILATRSGSATLRSTLDNIE 252 Query: 257 RLYVFQAVGHNRLLIAEGLALDGIYADWWQQLWLIGSVVAALCGFSIVLMFYLVAALKRR 316 RLYV+Q L++ G +L+ IY WW+Q+++IG ++ L F I F L + RR Sbjct: 253 RLYVWQN-SDRALVVVVGKSLESIYGPWWRQVFIIGGLMLMLSAFVIGAAFLLAREMARR 311 Query: 317 AAAEDRLAHLASTDALTGLANRRRLDDTLDVEWRRGMRAKAPVSLLMIDVDHFKIYNDTY 376 A AE RLA LA+TDALTG+ NRRR D+ + EWRRG + K P+SLLMID DHFK +ND + Sbjct: 312 ADAEQRLAQLATTDALTGIDNRRRFDERMLDEWRRGWQ-KLPLSLLMIDADHFKTFNDLF 370 Query: 377 GHQAGDAVLTTVGRCIASSAKRATDLGARYGGEEFSVLLPGIGKTGALEIAERIRAKLAA 436 GHQ GD VL + + IA S++R D ARYGGEEF++LLP A+ IAE IR ++ Sbjct: 371 GHQEGDQVLVRIAKSIAQSSRRPADCAARYGGEEFALLLPDTELDDAMRIAEEIRTRVER 430 Query: 437 ARESEPELPTVSIGLSCLVPDHERTSRDLLKAADLALYQAKREGRDRVI-VSP 488 +E TVSIG++C+VPD +SR+L++AAD ALYQAK +GR+R + V P Sbjct: 431 L-STEKWATTVSIGVACVVPDMAGSSRNLIEAADKALYQAKEQGRNRCVGVDP 482 >ref|YP_372356.1| diguanylate cyclase [Burkholderia sp. 383] gb|ABB11712.1| diguanylate cyclase [Burkholderia sp. 383] Length = 492 Score = 384 bits (986), Expect = e-104, Method: Compositional matrix adjust. Identities = 207/484 (42%), Positives = 287/484 (59%), Gaps = 6/484 (1%) Query: 7 KPKAVPTKRLLALGIGLVLCFSAICASILWEMASKDYRHAKEGATNLVASIASEIDRNID 66 P++ ++ G + +C L++ A++ + NL +I+RNI+ Sbjct: 2 HPRSAAPYYVVLAGTLIACALMGLCILQLFQSRHDALDRARDTSRNLALVAERDIERNIE 61 Query: 67 LYDLSLQAVADGVKLPELGKISPELRQVVLFDRAATAKDLGSILVLNAAGDVTLDSRTLT 126 LY LSL+AV G++ P++ SP LR+ +LFD A TAK LGS+LVL++AG++ LDS Sbjct: 62 LYGLSLEAVIQGLQRPDVMAASPALRRGILFDHAMTAKFLGSMLVLDSAGNIILDSANDV 121 Query: 127 PRTANFADRDFFRAHQTRADSGLFISAPWITS--DGEYLISLSRRINNDDGSFAGVVAGS 184 PR NF DR +F H+ D+GL+IS P+ + G ++L+RR++N DGSF G+V + Sbjct: 122 PRQGNFGDRKYFTVHRDNPDAGLYISDPYASRLRGGSLSVALTRRVSNPDGSFGGIVMIA 181 Query: 185 MRLSYFHNLFRKLNFGFGDSMALFNSDGVILMRAPFDISKIGQSIKDSLVFKQFPARQSG 244 + L YFH LF L G +++L +DG++ MR P+D+ IG+ I + F+ F G Sbjct: 182 VNLEYFHTLFAGLALGSHGAISLVGTDGIMFMRQPYDVHTIGRDISKAATFRHFLTAPEG 241 Query: 245 SYITKSIVDHVSRLYVFQAVGHNRLLIAEGLALDGIYADWWQQLWLIGSVVAALCGFSIV 304 S++ S +D+V RLY F+ + H L+I A IYA W + IG++VA IV Sbjct: 242 SFLDTSTIDNVRRLYYFKTLPHLPLIIMVAEAEQDIYAAWRHRAITIGALVATFGAAFIV 301 Query: 305 LMFYLVAALKRRAAAEDRLAHLASTDALTGLANRRRLDDTLDVEWRRGMRAKAPVSLLMI 364 L F L L+RR AE L LA TD LTGL NRR + LD+EWRR RA++ SLL + Sbjct: 302 LSFMLGTQLRRRMRAESELVMLARTDGLTGLNNRRSFGEVLDLEWRRARRARSVFSLLFV 361 Query: 365 DVDHFKIYNDTYGHQAGDAVLTTVGRCIASSAKRATDLGARYGGEEFSVLLPGIGKTGAL 424 DVD FK +NDTYGHQAGD LT V RCI + +R D ARYGGEEF V+LP TGA Sbjct: 362 DVDRFKAFNDTYGHQAGDDALTAVARCIGDNIRRPADTAARYGGEEFVVILPDTPATGAT 421 Query: 425 EIAERIRAKL--AAARESEPELP--TVSIGLSCLVPDHERTSRDLLKAADLALYQAKREG 480 EIAERIRA + A +E E T SIG++ P+ E ++KAAD ALY AK G Sbjct: 422 EIAERIRAAIDGLAIEHAESEFGRVTASIGVASWAPEQEGEVESVIKAADEALYHAKETG 481 Query: 481 RDRV 484 R++V Sbjct: 482 RNKV 485 >ref|YP_002287933.1| diguanylate cyclase [Oligotropha carboxidovorans OM5] gb|ACI92068.1| diguanylate cyclase [Oligotropha carboxidovorans OM5] Length = 493 Score = 384 bits (986), Expect = e-104, Method: Compositional matrix adjust. Identities = 208/473 (43%), Positives = 298/473 (63%), Gaps = 11/473 (2%) Query: 23 LVLC------FSAICASILWEMASKDYRHAKEGATNLVASIASEIDRNIDLYDLSLQAVA 76 +VLC F IC S+L E A+ + NL A+I S+I R+I++YDLSL+ Sbjct: 18 VVLCALTTSAFLLICGSVLLETRRAAGELARSASANLAATIDSDIVRSIEVYDLSLRNAV 77 Query: 77 DGVKLPELGKISPELRQVVLFDRAATAKDLGSILVLNAAGDVTLDSRTLTPRTANFADRD 136 + + + +IS + ++LFD AATA+ G I + + G + LDS TL P + AD++ Sbjct: 78 NNMLTLDTERISLPILHLILFDHAATAQHYGRIRIFDETGKLKLDSSTLHPAQESCADKE 137 Query: 137 FFRAHQTRADSGLFISAPWITSDGEYLISLSRRINNDDGSFAGVVAGSMRLSYFHNLFRK 196 FF+ H+ +D+GL++S P + + L+ LSRRI DG F GVV GS+R SYF +LF Sbjct: 138 FFKIHRASSDAGLYVSDPEVGTGAPALV-LSRRITGHDGRFLGVVVGSIRYSYFRDLFSH 196 Query: 197 LNFGFGDSMALFNSDGVILMRAPFDISKIGQSIKDSLVFKQFPARQSGSYITKSIVDHVS 256 L FG GD+ +F +DG ++MR P + IG+ + +S +Q A +SGS +S +D++ Sbjct: 197 LKFGEGDTATVFRNDGRVMMRQPSNSDTIGKDLSNSAGVRQILATRSGSATLRSTLDNIE 256 Query: 257 RLYVFQAVGHNRLLIAEGLALDGIYADWWQQLWLIGSVVAALCGFSIVLMFYLVAALKRR 316 RLYV+Q L++ G +L+ IY WW+Q+++IG ++ L F I F L + RR Sbjct: 257 RLYVWQN-SDRALVVVVGKSLESIYGPWWRQVFIIGGLMLMLSAFVIGAAFLLAREMARR 315 Query: 317 AAAEDRLAHLASTDALTGLANRRRLDDTLDVEWRRGMRAKAPVSLLMIDVDHFKIYNDTY 376 A AE RLA LA+TDALTG+ NRRR D+ + EWRRG + K P+SLLMID DHFK +ND + Sbjct: 316 ADAEQRLAQLATTDALTGIDNRRRFDERMLDEWRRGWQ-KLPLSLLMIDADHFKTFNDLF 374 Query: 377 GHQAGDAVLTTVGRCIASSAKRATDLGARYGGEEFSVLLPGIGKTGALEIAERIRAKLAA 436 GHQ GD VL + + IA S++R D ARYGGEEF++LLP A+ IAE IR ++ Sbjct: 375 GHQEGDQVLVRIAKSIAQSSRRPADCAARYGGEEFALLLPDTELDDAMRIAEEIRTRVER 434 Query: 437 ARESEPELPTVSIGLSCLVPDHERTSRDLLKAADLALYQAKREGRDRVI-VSP 488 +E TVSIG++C+VPD +SR+L++AAD ALYQAK +GR+R + V P Sbjct: 435 L-STEKWATTVSIGVACVVPDMAGSSRNLIEAADKALYQAKEQGRNRCVGVDP 486