BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0127.0036.p (398 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002131109.1| NADPH:quinone reductase [Phenylobacterium zu... 332 9e-89 ref|YP_743919.1| alcohol dehydrogenase [Granulibacter bethesdens... 288 1e-75 ref|ZP_03626748.1| Alcohol dehydrogenase zinc-binding domain pro... 268 1e-69 ref|YP_720482.1| zinc-binding alcohol dehydrogenase [Trichodesmi... 267 3e-69 ref|YP_004862832.1| NADPH:quinone reductase-like Zn-dependent ox... 267 3e-69 >ref|YP_002131109.1| NADPH:quinone reductase [Phenylobacterium zucineum HLK1] gb|ACG78680.1| NADPH:quinone reductase [Phenylobacterium zucineum HLK1] Length = 339 Score = 332 bits (850), Expect = 9e-89, Method: Compositional matrix adjust. Identities = 164/339 (48%), Positives = 219/339 (64%), Gaps = 1/339 (0%) Query: 61 LRVWTVTEPWGTENLALSEVADPLPNDGEVRIRMRAASLNYRDLLIVSGRHVGGALRNGA 120 +R VT PWG + + + EV +P P G+V +RM+A SLNYRD L++ G + A Sbjct: 1 MRALNVTAPWGPDAIQVVEVPEPTPGPGQVLVRMKACSLNYRDFLMIHGMYGRAAASATD 60 Query: 121 PIIPLGDGCGVIDMVGEGVERFQVGDRVIPLMIPNWRSGPVTPAKMAGALGLHTAGLARE 180 I P DGCG ++ VG GV RF+ GDRV L NW SGP T K++ ALG G E Sbjct: 61 IITPFSDGCGYVEAVGPGVTRFKAGDRVSTLFFQNWVSGPPTLEKLSSALGFPIPGAGAE 120 Query: 181 LAVFDESHLIKAPAYLTDHEAACLACATLTAWSALFEGRGLRPGEVAVIQGTGSVSLALL 240 L VF + L K P +LTDHE A L CA LTAW LF L PG+ V+QGTG VS+ L Sbjct: 121 LQVFSQEGLSKVPDFLTDHEVATLPCAALTAWRGLFHDARLEPGDTVVLQGTGGVSIFGL 180 Query: 241 QFAKAAGLRTIVTSSSDEKLASVRALGAAHGINYRTQTKWADAVRDLTDGAGADFILDMG 300 QFAKAAG RT++TSSSD KL +ALGA H +NY+T W+ VR+ T G GADFI+++G Sbjct: 181 QFAKAAGYRTLITSSSDAKLERAKALGADHLVNYKTTPAWSKPVREATGGRGADFIMEVG 240 Query: 301 AMGSLAESLRALRMEGQIAVVGILDGS-SALEPAQLLASAARIRGITVGSSEMFNAMTRA 359 G++ ES++A+++ G IAV+GI+ G+ PA L+ ++A+++G++VGS +MF +M RA Sbjct: 241 GGGTIQESMKAIKIGGHIAVIGIVAGAGEPFNPAALIGNSAKLQGLSVGSRDMFESMCRA 300 Query: 360 LTLHEIHPVVGKVLAWTEAPTGFEMLGTGNQFGKVVLEF 398 + LH + PVV KV WTEA +G G FGK+VLEF Sbjct: 301 IELHGVRPVVDKVYPWTEAKAAIAAMGGGEHFGKIVLEF 339 >ref|YP_743919.1| alcohol dehydrogenase [Granulibacter bethesdensis CGDNIH1] gb|ABI60996.1| alcohol dehydrogenase [Granulibacter bethesdensis CGDNIH1] Length = 343 Score = 288 bits (737), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 150/331 (45%), Positives = 207/331 (62%), Gaps = 4/331 (1%) Query: 69 PWGTENLALSEVADPLPNDGEVRIRMRAASLNYRDLLIVSGRHVGGALRNGAP-IIPLGD 127 P G ++L +E +P P G+V +R+RAASLNYRDLL+ G++ L P +IPL D Sbjct: 14 PQGFDSLYTTEAPEPKPRRGQVLVRLRAASLNYRDLLVARGQY---PLSPVPPDLIPLSD 70 Query: 128 GCGVIDMVGEGVERFQVGDRVIPLMIPNWRSGPVTPAKMAGALGLHTAGLARELAVFDES 187 G G + GE V RFQ GDRV P +W GP+T A ALG G+ E AVF++ Sbjct: 71 GAGEVVETGEDVTRFQPGDRVAPCFFQSWHDGPITERDGASALGGAIHGVLTEYAVFEQD 130 Query: 188 HLIKAPAYLTDHEAACLACATLTAWSALFEGRGLRPGEVAVIQGTGSVSLALLQFAKAAG 247 L++ P +L+ EAACL CA +TAW ALF G ++PG+ + QGTG VS+ +QFAKAAG Sbjct: 131 GLVRIPDHLSWEEAACLPCAAVTAWHALFGGTPVQPGQTVLTQGTGGVSIFAIQFAKAAG 190 Query: 248 LRTIVTSSSDEKLASVRALGAAHGINYRTQTKWADAVRDLTDGAGADFILDMGAMGSLAE 307 R I TSSSD+KL+ +ALGA GINYR++ W A LT G G D ++++G G+L + Sbjct: 191 ARVITTSSSDKKLSRAQALGADEGINYRSRPDWHKAATALTGGLGVDHVVEVGGSGTLPQ 250 Query: 308 SLRALRMEGQIAVVGILDGSSALEPAQLLASAARIRGITVGSSEMFNAMTRALTLHEIHP 367 S+RA R+ GQI ++G+L G + + P L+A + +RGI VGS MF AM A++ H I P Sbjct: 251 SIRATRLGGQIHLIGVLTGQNEINPLPLMARSQTLRGIYVGSRAMFEAMNVAISQHRIRP 310 Query: 368 VVGKVLAWTEAPTGFEMLGTGNQFGKVVLEF 398 V+ +V + EA + L + FGKVV+ Sbjct: 311 VIDRVFPFAEAVAAYRHLESATHFGKVVIRL 341 >ref|ZP_03626748.1| Alcohol dehydrogenase zinc-binding domain protein [bacterium Ellin514] gb|EEF62724.1| Alcohol dehydrogenase zinc-binding domain protein [bacterium Ellin514] Length = 335 Score = 268 bits (685), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 141/331 (42%), Positives = 203/331 (61%), Gaps = 3/331 (0%) Query: 68 EPWGTENLALSEVADPLPNDGEVRIRMRAASLNYRDLLIVSGRHVGGALRNGAPIIPLGD 127 + +G E+LA++E P P G+ ++MRA SLN+RDL++V G H L+ P++PL D Sbjct: 7 QKFGLESLAMAERPMPKPAAGQALVKMRAVSLNFRDLMMVKG-HYNPKLK--MPLVPLSD 63 Query: 128 GCGVIDMVGEGVERFQVGDRVIPLMIPNWRSGPVTPAKMAGALGLHTAGLARELAVFDES 187 G G + VG G +R +VGDRV + + W +G V+ ALG G+A E +FDE Sbjct: 64 GVGEVVEVGPGAKRVKVGDRVCGIFMQRWLAGGVSDEVADSALGGAINGVAAEYVLFDED 123 Query: 188 HLIKAPAYLTDHEAACLACATLTAWSALFEGRGLRPGEVAVIQGTGSVSLALLQFAKAAG 247 L++ P +LTD EAA L CA +TAW+A+ ++ G+ ++QGTG VSL LQFAK Sbjct: 124 GLVQVPKHLTDEEAATLPCAAVTAWNAVMVSGRVKAGDTVLLQGTGGVSLFALQFAKLHN 183 Query: 248 LRTIVTSSSDEKLASVRALGAAHGINYRTQTKWADAVRDLTDGAGADFILDMGAMGSLAE 307 R I+TSSSD+KL + LGA INY+T W + R LT G D I+++G G+LA+ Sbjct: 184 ARVIITSSSDDKLERAKKLGADELINYKTTPDWEEKARGLTHKTGVDHIVEVGGAGTLAK 243 Query: 308 SLRALRMEGQIAVVGILDGSSALEPAQLLASAARIRGITVGSSEMFNAMTRALTLHEIHP 367 SLRA+ G IA++G+L G + P +L + R++GI VGS EMF AM RA+ ++ P Sbjct: 244 SLRAVCAGGHIALIGVLTGGGEVNPIPILMKSVRVQGIYVGSREMFEAMNRAIEQSQLRP 303 Query: 368 VVGKVLAWTEAPTGFEMLGTGNQFGKVVLEF 398 VV KV + E P + + TG FGK+V++ Sbjct: 304 VVDKVFRFEELPQALKYMETGAHFGKIVVKI 334 >ref|YP_720482.1| zinc-binding alcohol dehydrogenase [Trichodesmium erythraeum IMS101] gb|ABG50009.1| Alcohol dehydrogenase, zinc-binding [Trichodesmium erythraeum IMS101] Length = 332 Score = 267 bits (682), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 142/328 (43%), Positives = 201/328 (61%), Gaps = 9/328 (2%) Query: 74 NLALSEVADPLPNDGEVRIRMRAASLNYRDLLIVSGRHVGGALRNGAPIIPLGDGCGVID 133 NL +E P P GEV ++++A SLNYRD+L+V G + P+IP DG G + Sbjct: 11 NLVCTERPQPEPKFGEVLVKVKAVSLNYRDILMVKGAY---NPHLPLPVIPCSDGVGEVV 67 Query: 134 MVGEGVERFQVGDRVIPLMIPNWRSGPVTPAKMAGALGLHTAGLARELAVFDESHLIKAP 193 VGEGV + + GDRV + + W SG +T ALG G+ E + E ++ P Sbjct: 68 SVGEGVTKVKPGDRVASIFMQKWLSGNLTREAARSALGGEIDGMLAEYVILSEDGVVNIP 127 Query: 194 AYLTDHEAACLACATLTAWSALFEGRGLRPGEVAVIQGTGSVSLALLQFAKAAGLRTIVT 253 +YL+D EAA L CA +TAW AL E GL+PGE ++ GTG VSL LQFA AG R I T Sbjct: 128 SYLSDIEAATLPCAAVTAWHALIEA-GLKPGETVLVMGTGGVSLFALQFAVMAGARVIAT 186 Query: 254 SSSDEKLASVRALGAAHGINYRTQTKWADAVRDLTDGAGADFILDMGAMGSLAESLRALR 313 SSSDEKLA V+ LGA+ INY++ KW V LT+G G D+++++G +L++SL+A++ Sbjct: 187 SSSDEKLARVKQLGASDMINYKSVPKWEKQVLALTEGTGVDYVVEVGGAKTLSQSLKAVK 246 Query: 314 MEGQIAVVGILDGSSA---LEPAQLLASAARIRGITVGSSEMFNAMTRALTLHEIHPVVG 370 + GQI+++GIL G+ A + PA L RI GI VGS +MF AM RA+ L ++HPV Sbjct: 247 IGGQISLIGILAGAQAEFNILPA--LMKEVRIHGIFVGSRQMFEAMNRAIDLSQLHPVCD 304 Query: 371 KVLAWTEAPTGFEMLGTGNQFGKVVLEF 398 ++ + AP + G+ FGK+ ++F Sbjct: 305 RIFPFESAPEALSYMEIGSHFGKITIQF 332 >ref|YP_004862832.1| NADPH:quinone reductase-like Zn-dependent oxidoreductase [Candidatus Chloracidobacterium thermophilum B] gb|AEP12316.1| NADPH:quinone reductase-like Zn-dependent oxidoreductase [Candidatus Chloracidobacterium thermophilum B] Length = 338 Score = 267 bits (682), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 147/338 (43%), Positives = 202/338 (59%), Gaps = 5/338 (1%) Query: 61 LRVWTVTEPWGTENLALSEVADPLPNDGEVRIRMRAASLNYRDLLIVSGRHVGGALRNGA 120 ++ + + +G E+L L+E P GEV IR+RA SLNYRDL+ V+G + + Sbjct: 1 MKCVELADQFGIEHLRLTERPHPELKFGEVLIRVRATSLNYRDLMTVTGVY---NPKQPL 57 Query: 121 PIIPLGDGCGVIDMVGEGVERFQVGDRVIPLMIPNWRSG-PVTPAKMAGALGLHTAGLAR 179 P+IPL DG G + VG+GV R VGDRV + W +G P LG G+ Sbjct: 58 PLIPLSDGVGEVVAVGDGVTRVAVGDRVAGIFAQGWTAGEPAVEKVRTTTLGGPLDGMLT 117 Query: 180 ELAVFDESHLIKAPAYLTDHEAACLACATLTAWSALFEGRGLRPGEVAVIQGTGSVSLAL 239 E + ++K P YL D EAA L CA LTAWSAL L+PG+ ++QGTG VS+ Sbjct: 118 EYRALSQEGVVKVPDYLNDEEAATLPCAALTAWSALIAHGQLKPGDTVLVQGTGGVSIFA 177 Query: 240 LQFAKAAGLRTIVTSSSDEKLASVRALGAAHGINYRTQTKWADAVRDLTDGAGADFILDM 299 LQFAKAAG R I+TS SDEKL +ALGA INYR W AVR++T G G D ++++ Sbjct: 178 LQFAKAAGARVIITSGSDEKLERAKALGADEVINYRQAPDWDKAVREMTAGRGVDHVVEV 237 Query: 300 GAMGSLAESLRALRMEGQIAVVGILDGSSA-LEPAQLLASAARIRGITVGSSEMFNAMTR 358 G G+LA+S+R++R G I+++G+L G + ++ A +L R++GI VGS EMF AM R Sbjct: 238 GGTGTLAKSIRSVRFGGHISLIGVLSGRTGEIDIAPVLMQNIRVQGIIVGSREMFEAMNR 297 Query: 359 ALTLHEIHPVVGKVLAWTEAPTGFEMLGTGNQFGKVVL 396 AL + I PVV K+ A EA F ++ G FGK+ + Sbjct: 298 ALEQNRIRPVVDKIFALDEARQAFGLMAQGGHFGKICI 335