BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0117.0073.p (310 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08627166.1| transcriptional regulator, MerR family [Brady... 439 e-121 ref|YP_003770838.1| MerR family transcriptional regulator [Amyco... 168 9e-40 ref|YP_001102675.1| MerR family transcriptional regulator [Sacch... 167 2e-39 ref|NP_823957.1| MerR family transcriptional regulator [Streptom... 165 1e-38 ref|ZP_07296476.1| putative MerR-family transcriptional regulato... 159 6e-37 >ref|ZP_08627166.1| transcriptional regulator, MerR family [Bradyrhizobiaceae bacterium SG-6C] gb|EGP10200.1| transcriptional regulator, MerR family [Bradyrhizobiaceae bacterium SG-6C] Length = 310 Score = 439 bits (1128), Expect = e-121, Method: Compositional matrix adjust. Identities = 222/309 (71%), Positives = 258/309 (83%) Query: 1 MTQRTYSIGEAARLSGISVRKLRFYSDQGLLPPAGRTASGYRVFTDGELVRLDLIRCLRD 60 MTQRTY+IGEAARLSGISVR+LRFYSD+GLLPPAGRT SGYRVFTD ELVRLDLIRCLRD Sbjct: 1 MTQRTYTIGEAARLSGISVRRLRFYSDKGLLPPAGRTESGYRVFTDEELVRLDLIRCLRD 60 Query: 61 AGLGLDAIREVLTKQLSLVEALRLRLETLEAEIAAQRRVASALRAALRSPQLTEADLRRF 120 AG+GLDAIR+VL ++LSL +AL+LRL LEAEIAAQRRVASALRAAL SP LTEADLRRF Sbjct: 61 AGIGLDAIRDVLARELSLTDALKLRLRALEAEIAAQRRVASALRAALASPALTEADLRRF 120 Query: 121 LTMTQLSRTERRNVVERFFEKVSDGVNIDRKWIRQMIETSVPELPDEPTPEQCDAWIELS 180 TMT LSR ERRNV+ERF+ +VS+ V ID +W+RQMIE S PELPD PTPEQCDAWIELS Sbjct: 121 WTMTNLSRLERRNVIERFYTQVSEDVRIDPEWMRQMIEASTPELPDNPTPEQCDAWIELS 180 Query: 181 EMLSDPSLVANIRANAEDVWNHHVLDLAAWQAANEIVLARAREIIARDLGPTSEAGQALA 240 +L+DP VAN+RANA++VWN + DL AWQAA E +A+A+ I + P SE ALA Sbjct: 181 SILADPDFVANMRANAKEVWNQNDFDLTAWQAAGEPFVAKAKAAIEQGHEPDSETAHALA 240 Query: 241 RDWLETSARLLKRKPDLEFRNWIRGKYALHDARAARYWELVAIMRGQSPDASPNREWAWI 300 ++WLETSAR++ R PD +++ W+R +YA HDARA RYWELVAIMRGQ P SPNREW WI Sbjct: 241 QEWLETSARVVGRIPDDDYKEWLRTRYAAHDARAVRYWELVAIMRGQPPQISPNREWNWI 300 Query: 301 TAAMRHHLS 309 AM+HHL+ Sbjct: 301 IDAMKHHLA 309 >ref|YP_003770838.1| MerR family transcriptional regulator [Amycolatopsis mediterranei U32] gb|ADJ50436.1| MerR family transcriptional regulator [Amycolatopsis mediterranei U32] gb|AEK47439.1| MerR family transcriptional regulator [Amycolatopsis mediterranei S699] Length = 311 Score = 168 bits (426), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 117/311 (37%), Positives = 183/311 (58%), Gaps = 10/311 (3%) Query: 2 TQRTYSIGEAARLSGISVRKLRFYSDQGLLPPAGRTASGYRVFTDGELVRLDLIRCLRDA 61 T T++IGE +R +G+ V+ +RFYSD+GLLPP RT +GYR++ + RL+L+R LR+ Sbjct: 3 TTATFTIGELSRRTGLPVKTIRFYSDEGLLPPTDRTDAGYRLYDAAAMARLELVRTLREL 62 Query: 62 GLGLDAIREVLTKQLSLVEALRLRLETLEAEIAAQRRVASALRAAL-RSPQLTEADLRRF 120 GLGL + LT+ ++ E +E L+ +I R + LRA R+ +L E +L Sbjct: 63 GLGLADVSAALTQSTTVGELAVRHVEALDEQIRRLRLRRAVLRAVAKRNSELEEVNLMNR 122 Query: 121 LTMTQLSRTERRNVVERFFEKVSDGVNIDRKWIRQMIETSVPELPDEPTPEQCDAWIELS 180 L +S ER+ +V+ F++++ G+++D+++ R+M PELPD+PTPEQ +AWIE + Sbjct: 123 L--ASMSDEERKRLVDEFWDEMVAGLDVDQEFYRRM-RAGKPELPDDPTPEQLEAWIEFA 179 Query: 181 EMLSDPSLVANIR----ANAEDVWNHHVLDLA-AWQAANEIVLARAREIIARDLGPTSEA 235 E++ DP+ A IR A+ + + A AW+ +ARA+E + PTSE Sbjct: 180 ELVQDPAFRALIRKMSETQAQQIQDGEFQQPAEAWRTHWNEWMARAQEAVDAGETPTSER 239 Query: 236 GQALARDWLETSARLLKRKPDLEFRNWIRGKYALH-DARAARYWELVAIMRGQSPDASPN 294 GQALA D SAR + EFR+ + ++A D RA RYW+L+AI+ G P A+ Sbjct: 240 GQALAADIAAASARPDQDAGSAEFRSELADRFAASGDPRAERYWQLLAIINGWPPVATTQ 299 Query: 295 REWAWITAAMR 305 ++ AA+R Sbjct: 300 PAVGFMIAALR 310 >ref|YP_001102675.1| MerR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] ref|ZP_06564213.1| MerR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] emb|CAL99749.1| MerR-family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] Length = 314 Score = 167 bits (424), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 101/313 (32%), Positives = 179/313 (57%), Gaps = 18/313 (5%) Query: 4 RTYSIGEAARLSGISVRKLRFYSDQGLLPPAGRTASGYRVFTDGELVRLDLIRCLRDAGL 63 R Y+IGE AR +G+ V+ +RFY+D G++PP RT SGYR++ + +L+L+R LR+ G Sbjct: 5 RLYTIGELARRTGLPVKTIRFYADSGVVPPTDRTHSGYRLYDVSAISKLELVRTLRELGA 64 Query: 64 GLDAIREVLTKQLSLVEALRLRLETLEAEIAAQRRVASALRAALRSPQLTEADLRRFLTM 123 GLD +R VL ++ +L + L LE ++ R + LRA ++ + TE ++R + Sbjct: 65 GLDEVRSVLERETTLPKLAEAHLALLEQQMRLLRTRRAVLRAVVKLRRTTE-EVRLMHKL 123 Query: 124 TQLSRTERRNVVERFFEKVSDGVNID---RKWIRQMIETSVPELPDEPTPEQCDAWIELS 180 ++S +ER +++ F++++++G+NI+ +W+R ++ P LP++P+ EQ +AWIEL+ Sbjct: 124 AKMSDSERNRLIDEFWDEMTEGLNINPDFAEWMR----SAKPNLPEDPSTEQVEAWIELA 179 Query: 181 EMLSDPSLVANIRANAEDVWNH----HVLDLAAWQAANEI--VLARAREIIARDLGPTSE 234 E+++DP +R+ +++ + + A + A++ V +AR+ P Sbjct: 180 ELVADPDFRHLVRSASQEHSDRRDAGETMSGPAPEDAHKWWEVTDQARQAAEAGTSPEGP 239 Query: 235 AGQALARDWLETSARLLKRKPDLEFRNWIRGKYALHDARAARYWELVAIMRG--QSPDAS 292 AL +E S + EFRNW+ Y HD R +RYWEL+A + G Q P+ Sbjct: 240 EAAALVARIVELSTEEYGKPDSAEFRNWLADYYQQHDERLSRYWELMATINGWPQHPNTE 299 Query: 293 PNREWAWITAAMR 305 + + W+ AA+R Sbjct: 300 ASSK--WLAAALR 310 >ref|NP_823957.1| MerR family transcriptional regulator [Streptomyces avermitilis MA-4680] dbj|BAC70492.1| putative MerR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length = 308 Score = 165 bits (417), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 105/305 (34%), Positives = 167/305 (54%), Gaps = 15/305 (4%) Query: 6 YSIGEAARLSGISVRKLRFYSDQGLLPPAGRTASGYRVFTDGELVRLDLIRCLRDAGLGL 65 ++IG+ AR +G+SVR +R++SD+G LPP R++ GYR++ G + RL+LIR LR+ GLGL Sbjct: 9 FTIGQLARRTGLSVRTIRYWSDEGALPPVTRSSGGYRLYDAGSVARLELIRTLRELGLGL 68 Query: 66 DAIREVLTKQLSLVEALRLRLETLEAEIAAQRRVASALRAALRSPQLTEADLRRFLTMTQ 125 D +REVL + ++ E + L+A+I A + + L R E ++ + + Sbjct: 69 DDVREVLAGETTVAEVAATHVTALDAQIRALKVTRAVLSTVARRGSTAE-EMTLMNKLAR 127 Query: 126 LSRTERRNVVERFFEKVSDGVNIDRKWIRQMIETSVPELPDEPTPEQCDAWIELSEMLSD 185 LS ERR ++E F +++ G++ IR+ + + +LPDEPTPEQ DAW+EL E+L D Sbjct: 128 LSAAERRRILEEFADEMFRGLDTADPVIRERMRNTAVDLPDEPTPEQVDAWVELVELLQD 187 Query: 186 PSLVANIRA----NAEDVWNHHVLDLAAWQAANEIVLAR-AREIIARDLGPTSEAGQALA 240 P A +RA NA D + + W + LA AR+ R + P + + + Sbjct: 188 PEFRAQMRAAAEFNAADRGHDSPAGASLWFVRRLVQLAADARQ---RGIAPEAPEAEEVL 244 Query: 241 RDWLETSARLLKRKPDLEFRNWIRGKYALHDARAARYWELVAIMRGQSPDASPNREWAWI 300 R+ L + R LE A + R ARY EL+A+++G P + E+ W+ Sbjct: 245 RELLGEADGAADRAAVLERLE------ATSNDRVARYRELLAVVKGGGPLPAHREEFGWV 298 Query: 301 TAAMR 305 AA+R Sbjct: 299 VAALR 303 >ref|ZP_07296476.1| putative MerR-family transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gb|EFL24845.1| putative MerR-family transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length = 314 Score = 159 bits (401), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 108/308 (35%), Positives = 165/308 (53%), Gaps = 17/308 (5%) Query: 6 YSIGEAARLSGISVRKLRFYSDQGLLPPAGRTASGYRVFTDGELVRLDLIRCLRDAGLGL 65 YSIGE +R +G++V+ +RFYSDQG++PP R+ +GYR++ L RL L R LRD GLGL Sbjct: 7 YSIGELSRRTGLTVKTIRFYSDQGIVPPTDRSPAGYRLYGPDALARLGLARTLRDLGLGL 66 Query: 66 DAIREVLTKQLSLVEALRLRLETLEAEIAAQRRVASALRA-ALRSPQLTEADLRRFLTMT 124 +R+VL ++ S+ E L+ +I R + LRA A R P E DL L Sbjct: 67 ATVRKVLDREASIPEVAEAHANALDVQIRTLRLRRAVLRAVAGRGPTPMEMDLMHRL--A 124 Query: 125 QLSRTERRNVVERFFEKVSDGVNIDRKWIRQMIETSVPELPDEPTPEQCDAWIELSEMLS 184 LS+TERR +V F + ++ + +++ ++ +++PE PD+PTP+Q AW+EL+E+ Sbjct: 125 TLSQTERRRLVADFIDDTFRDLDTNPEFV-TLMRSAMPEFPDDPTPDQVGAWVELAELCQ 183 Query: 185 DPSLVANIR----ANAEDVWNHHVLDLAAWQAANEIVLARAREIIARDLGPTSEAGQALA 240 D A +R AED V +L N+ + R E ++ L P S + Sbjct: 184 DADFRAVVRHIAEEQAEDPSPQGVSNL--HDGLNQAMRERMDEAVSVGLLPASVNTGPDS 241 Query: 241 RDWLETSARLLKRKPDLEFRNWIRGKYALH-DARAARYWELVAIMRG--QSPDASPNREW 297 L A +R D + R W+ + + RAARYW+L+A + G SP +P + Sbjct: 242 LGGLYGHA--FERAGDGDLRRWLLARLQMTAHPRAARYWQLLATINGWPTSPTLAP--VY 297 Query: 298 AWITAAMR 305 W T A+R Sbjct: 298 TWFTTALR 305