BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0115.0146.p (455 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003696271.1| aldehyde dehydrogenase [Starkeya novella DSM... 632 e-179 ref|YP_001110476.1| aldehyde dehydrogenase [Burkholderia vietnam... 621 e-175 ref|YP_004305287.1| aldehyde dehydrogenase 1A1-like protein [Pol... 592 e-167 ref|ZP_01549186.1| dehydrogenase, (succinatesemialdehyde dehydro... 588 e-166 ref|YP_004610457.1| aldehyde dehydrogenase [Mesorhizobium opport... 587 e-165 >ref|YP_003696271.1| aldehyde dehydrogenase [Starkeya novella DSM 506] gb|ADH91652.1| Aldehyde Dehydrogenase [Starkeya novella DSM 506] Length = 461 Score = 632 bits (1629), Expect = e-179, Method: Compositional matrix adjust. Identities = 319/459 (69%), Positives = 363/459 (79%), Gaps = 7/459 (1%) Query: 1 VNDIVCISPVDGSEVARRPVATGAEVAAALAQARKAQQEWSRVPLAERKAMMLAFLHEMR 60 ++DIVCISP+DGSE+ RRP AT A +A AL AR AQ+EW +VP+AER A +L FL M Sbjct: 1 MSDIVCISPIDGSELVRRPAATEAALAQALEAARAAQREWLKVPIAERSAYVLRFLDAML 60 Query: 61 AQNDEVVPELAMQMGRPVRYGGELRSLEERVRALVELSDEALAPIVPA-ERPGFRRMIKR 119 A N E+VPELA QMGRPVRYGGE R EERVR +V+++++ALAP+VP ERPGF R I+R Sbjct: 61 AMNQEIVPELAQQMGRPVRYGGEFRGFEERVRYVVDMAEDALAPVVPHDERPGFTRYIRR 120 Query: 120 VPAGIVLVIAPWNYPYLTAANTIVPALLAGNAVILKHAAQTLLVGERFQAALDRVGLPKG 179 P GIVLV+APWNYPYLTA NTI PAL+AGNAV+LKHAAQT+LVGERFQ A+DR GLPKG Sbjct: 121 DPLGIVLVVAPWNYPYLTAVNTIAPALIAGNAVLLKHAAQTILVGERFQMAMDRAGLPKG 180 Query: 180 LFRTLTLDHGVTRELISSRSVDHVNFX------RAVERAAAGTFISLGLELGGKDPAYVR 233 LF L L H T +LI S +VD VNF RA+ERAAAGTF LGLELGGKDPAYVR Sbjct: 181 LFANLVLTHDQTSKLIGSDAVDFVNFTGSVEGGRAIERAAAGTFTPLGLELGGKDPAYVR 240 Query: 234 PDADFDFAVEQLVDGAFYNSGQCCCGIERIYVHERIYGSFVDAFADLTARYRLGNPLSRD 293 DADFDF VE LVDGAFYNSGQCCCGIERIYV E +Y FVD+F LT +Y LGNPL Sbjct: 241 ADADFDFTVENLVDGAFYNSGQCCCGIERIYVQESLYDRFVDSFVALTGKYVLGNPLDDA 300 Query: 294 TTLGPMAATRFADAVRAHIGEAVAKGARPLIDPARFPADKIGTAYLMPQVLVGVDHSMRV 353 TTLGPMA RFA+ +R EAVAKGA+ +DPA FPA++ GT YL PQVL GVDHSM V Sbjct: 301 TTLGPMAQGRFAELIRRQTAEAVAKGAKAHLDPAAFPANREGTPYLAPQVLTGVDHSMSV 360 Query: 354 MMEESFGPVVGLMKVSSDQEAIGLMNDSPYGLTASVWTEDAAAAERIGDGIATGTMFMNR 413 M EESFGPVVG+MKV D EA+ LMNDS YGLTAS+WT D AAERIG + TGT+FMNR Sbjct: 361 MREESFGPVVGIMKVKDDDEALKLMNDSVYGLTASIWTADLEAAERIGGEVETGTVFMNR 420 Query: 414 CDYVDPALAWTGVKDTGRGAGMSRLGFAALTRPKSFHLR 452 CDY+DP LAWTGVK+TGRGA +SR+GF LTRPKSFHLR Sbjct: 421 CDYLDPGLAWTGVKETGRGASLSRIGFEMLTRPKSFHLR 459 >ref|YP_001110476.1| aldehyde dehydrogenase [Burkholderia vietnamiensis G4] gb|ABO59673.1| aldehyde dehydrogenase [Burkholderia vietnamiensis G4] Length = 462 Score = 621 bits (1601), Expect = e-175, Method: Compositional matrix adjust. Identities = 296/459 (64%), Positives = 356/459 (77%), Gaps = 7/459 (1%) Query: 1 VNDIVCISPVDGSEVARRPVATGAEVAAALAQARKAQQEWSRVPLAERKAMMLAFLHEMR 60 ++D VC+SPVDG E+ARRP + V L QAR AQ+EW++VP+AER A ++ F+ MR Sbjct: 1 MSDFVCVSPVDGRELARRPYMSDQAVKGVLQQARAAQREWAQVPIAERAAYVMRFVEAMR 60 Query: 61 AQNDEVVPELAMQMGRPVRYGGELRSLEERVRALVELSDEALAPIVP-AERPGFRRMIKR 119 A + ++VPELA+QMGRPVRYGGE RS EERVR +V +++ +LAP E+ G +R IKR Sbjct: 61 AMDSDIVPELALQMGRPVRYGGEFRSFEERVRYMVNIAESSLAPTTAFDEQAGIQRFIKR 120 Query: 120 VPAGIVLVIAPWNYPYLTAANTIVPALLAGNAVILKHAAQTLLVGERFQAALDRVGLPKG 179 P GIVL IAPWNYPYLTAAN+I+PAL+AGNAVILKHAAQTLLVGERF AA + GLP G Sbjct: 121 EPLGIVLTIAPWNYPYLTAANSIIPALMAGNAVILKHAAQTLLVGERFAAAFAKAGLPSG 180 Query: 180 LFRTLTLDHGVTRELISSRSVDHVNFX------RAVERAAAGTFISLGLELGGKDPAYVR 233 LF + + H L + V+HV+F RAVERAAAG+F ++GLELGGKDP YVR Sbjct: 181 LFANVAISHEQVSRLTGAGEVNHVSFTGSVAGGRAVERAAAGSFTTIGLELGGKDPGYVR 240 Query: 234 PDADFDFAVEQLVDGAFYNSGQCCCGIERIYVHERIYGSFVDAFADLTARYRLGNPLSRD 293 PDAD AVE LVDGAF+NSGQCCC IERIYVHE+++ FV+ + + Y LGNPL Sbjct: 241 PDADVRKAVETLVDGAFFNSGQCCCAIERIYVHEKLFDEFVEQAVSIASGYVLGNPLEAG 300 Query: 294 TTLGPMAATRFADAVRAHIGEAVAKGARPLIDPARFPADKIGTAYLMPQVLVGVDHSMRV 353 TTLGPMAA RFAD VR+ I EAVA GA+PL+D F AD+ GTAYL PQ+ V V+HSMR+ Sbjct: 301 TTLGPMAAVRFADGVRSQIQEAVAAGAKPLLDSRSFSADREGTAYLAPQIFVNVNHSMRM 360 Query: 354 MMEESFGPVVGLMKVSSDQEAIGLMNDSPYGLTASVWTEDAAAAERIGDGIATGTMFMNR 413 M+EE+FGP+VG+MKV SD+EA+ LMNDSPYGLTAS+WT DA AA R+GD I TGT+FMNR Sbjct: 361 MVEETFGPIVGIMKVKSDEEAVQLMNDSPYGLTASIWTNDADAARRLGDRIETGTVFMNR 420 Query: 414 CDYVDPALAWTGVKDTGRGAGMSRLGFAALTRPKSFHLR 452 CDYVDP LAWTGVKDTGRG +SRLG+ ALTRPKSFHLR Sbjct: 421 CDYVDPGLAWTGVKDTGRGVSLSRLGYDALTRPKSFHLR 459 >ref|YP_004305287.1| aldehyde dehydrogenase 1A1-like protein [Polymorphum gilvum SL003B-26A1] gb|ADZ71983.1| putative aldehyde dehydrogenase 1A1-like protein [Polymorphum gilvum SL003B-26A1] Length = 462 Score = 592 bits (1526), Expect = e-167, Method: Compositional matrix adjust. Identities = 292/455 (64%), Positives = 339/455 (74%), Gaps = 6/455 (1%) Query: 7 ISPVDGSEVARRPVATGAEVAAALAQARKAQQEWSRVPLAERKAMMLAFLHEMRAQNDEV 66 ISPVDGS A RP A A V A++ A+ AQ++W+ PL R A+ L L + A NDE+ Sbjct: 8 ISPVDGSVYAERPTADAAAVDRAVSAAKAAQRDWAATPLDTRVALCLKALDALLAMNDEI 67 Query: 67 VPELAMQMGRPVRYGGELRSLEERVRALVELSDEALAPIVPAERPGFRRMIKRVPAGIVL 126 VPEL QMGRPVRYGGE LEER R + ++ ALAPI +RPGF+R + P G+V+ Sbjct: 68 VPELTWQMGRPVRYGGEKGGLEERARYMAGIAAGALAPIERTDRPGFKRYLTHEPLGVVM 127 Query: 127 VIAPWNYPYLTAANTIVPALLAGNAVILKHAAQTLLVGERFQAALDRVGLPKGLFRTLTL 186 VIAPWNYPYLTA NTI PAL+AGNAV+LKHAAQTLLVGERF A ++ GLPKG+F+ + L Sbjct: 128 VIAPWNYPYLTAGNTIFPALMAGNAVLLKHAAQTLLVGERFAMAFEKAGLPKGVFQNIVL 187 Query: 187 DHGVTRELISSRSVDHVNFX------RAVERAAAGTFISLGLELGGKDPAYVRPDADFDF 240 H T L+ S +DHVNF +A+E+A AGTF +LGLELGGKDPAYV DA+ D+ Sbjct: 188 SHDGTETLLGSGLIDHVNFTGSVAGGKAIEKALAGTFATLGLELGGKDPAYVMADANLDY 247 Query: 241 AVEQLVDGAFYNSGQCCCGIERIYVHERIYGSFVDAFADLTARYRLGNPLSRDTTLGPMA 300 AV LVDGAFYNSGQCCCGIERIYVHE Y +FVD F +LT +Y LGNPL +TT+GPMA Sbjct: 248 AVANLVDGAFYNSGQCCCGIERIYVHESRYDAFVDGFVNLTRQYTLGNPLDPETTIGPMA 307 Query: 301 ATRFADAVRAHIGEAVAKGARPLIDPARFPADKIGTAYLMPQVLVGVDHSMRVMMEESFG 360 RFA VR EA+ KGA+ ID A FPADK GT YL PQVL V+H M VM EESFG Sbjct: 308 QARFAAWVREQTEEALRKGAKAHIDTAAFPADKAGTPYLAPQVLTNVNHQMSVMREESFG 367 Query: 361 PVVGLMKVSSDQEAIGLMNDSPYGLTASVWTEDAAAAERIGDGIATGTMFMNRCDYVDPA 420 PVVG+MKV D EAI LMNDSPYGLTAS+WTED AAAE IG I TGT+FMNRCDYVDP Sbjct: 368 PVVGIMKVKDDAEAIQLMNDSPYGLTASIWTEDLAAAEHIGHQIDTGTVFMNRCDYVDPG 427 Query: 421 LAWTGVKDTGRGAGMSRLGFAALTRPKSFHLRIEH 455 L WTGVKDTG+GA +S +GFA LTRPKSFHLR+EH Sbjct: 428 LVWTGVKDTGKGAALSEIGFANLTRPKSFHLRVEH 462 >ref|ZP_01549186.1| dehydrogenase, (succinatesemialdehyde dehydrogenase, aldehyde dehydrogenase, aldehyde dehydrogenase) [Stappia aggregata IAM 12614] gb|EAV42428.1| dehydrogenase, (succinatesemialdehyde dehydrogenase, aldehyde dehydrogenase, aldehyde dehydrogenase) [Stappia aggregata IAM 12614] Length = 462 Score = 588 bits (1517), Expect = e-166, Method: Compositional matrix adjust. Identities = 281/458 (61%), Positives = 342/458 (74%), Gaps = 6/458 (1%) Query: 4 IVCISPVDGSEVARRPVATGAEVAAALAQARKAQQEWSRVPLAERKAMMLAFLHEMRAQN 63 I ISP+DGS A RP A V ++ AR AQ W+ +P+AER A L L ++A N Sbjct: 5 IKLISPIDGSVYAERPALDDAAVDRVVSAARTAQPGWAALPVAERVAYCLKALEALKAMN 64 Query: 64 DEVVPELAMQMGRPVRYGGELRSLEERVRALVELSDEALAPIVPAERPGFRRMIKRVPAG 123 DEVVPELA QMGRPVR+GGEL ER +++ EALA + ++PGF+R ++RVP G Sbjct: 65 DEVVPELAWQMGRPVRFGGELGGTIERTEYCAKIAAEALADVERTDKPGFKRYLRRVPLG 124 Query: 124 IVLVIAPWNYPYLTAANTIVPALLAGNAVILKHAAQTLLVGERFQAALDRVGLPKGLFRT 183 +V+VIAPWNYP++TA NTI+PAL+AGN ++LKHAAQTLLVGER A + GLPKG+F+ Sbjct: 125 VVMVIAPWNYPFMTAINTIMPALMAGNVIVLKHAAQTLLVGERLAKAFEIAGLPKGVFQN 184 Query: 184 LTLDHGVTRELISSRSVDHVNFX------RAVERAAAGTFISLGLELGGKDPAYVRPDAD 237 + L H T +L+ S +DHVNF RA+E+A AGTF +LGLELGGKDPAYVR DAD Sbjct: 185 IVLTHRGTEKLLGSGLIDHVNFTGSVGGGRAIEKALAGTFATLGLELGGKDPAYVRADAD 244 Query: 238 FDFAVEQLVDGAFYNSGQCCCGIERIYVHERIYGSFVDAFADLTARYRLGNPLSRDTTLG 297 ++AVE LVDGAFYN+GQCCCGIER+YVHE +Y FV+ F DLT++Y+LGNPL TTLG Sbjct: 245 LNYAVENLVDGAFYNAGQCCCGIERVYVHESLYDRFVEGFVDLTSQYKLGNPLDEATTLG 304 Query: 298 PMAATRFADAVRAHIGEAVAKGARPLIDPARFPADKIGTAYLMPQVLVGVDHSMRVMMEE 357 PMA RFA +R EA+ KGA+ ID ++F ADK GT YL PQVL V+H M VM EE Sbjct: 305 PMAQARFAAWIREQTQEALRKGAKAHIDTSKFEADKEGTPYLAPQVLTNVNHQMSVMREE 364 Query: 358 SFGPVVGLMKVSSDQEAIGLMNDSPYGLTASVWTEDAAAAERIGDGIATGTMFMNRCDYV 417 SFGPVVG+MKV D+EA+ MNDSPYGLTAS+WTEDA AA IGD I TGT+FMNRCDY+ Sbjct: 365 SFGPVVGIMKVKDDEEALQFMNDSPYGLTASIWTEDAQAAGEIGDRIETGTVFMNRCDYL 424 Query: 418 DPALAWTGVKDTGRGAGMSRLGFAALTRPKSFHLRIEH 455 DPAL WTGVKDTG+GA +S +GF LTRPKSFH R+EH Sbjct: 425 DPALVWTGVKDTGKGAALSEIGFHNLTRPKSFHFRLEH 462 >ref|YP_004610457.1| aldehyde dehydrogenase [Mesorhizobium opportunistum WSM2075] gb|AEH86363.1| Aldehyde Dehydrogenase [Mesorhizobium opportunistum WSM2075] Length = 462 Score = 587 bits (1512), Expect = e-165, Method: Compositional matrix adjust. Identities = 280/457 (61%), Positives = 346/457 (75%), Gaps = 10/457 (2%) Query: 4 IVCISPVDGSEVARRPVATGAEVAAALAQARKAQQEWSRVPLAERKAMMLAFLHEMRAQN 63 + I+PVDGS A RP+AT V AA+ +A+ AQ++W++VP+ ER MLA L + A Sbjct: 5 VKLITPVDGSIYAERPIATDQAVNAAVERAKAAQEKWAQVPIVERGKYMLAMLEALVAMT 64 Query: 64 DEVVPELAMQMGRPVRYGGELRSLEERVRALVELSDEALAPIVPAERP--GFRRMIKRVP 121 DE+VPE+A QMGRPVRYGGE ++ER +VE+++ AL VPA P GFRR +K+ P Sbjct: 65 DEIVPEIAWQMGRPVRYGGEFGGVKERTNYMVEIAEAALKS-VPASNPKDGFRRYVKKDP 123 Query: 122 AGIVLVIAPWNYPYLTAANTIVPALLAGNAVILKHAAQTLLVGERFQAALDRVGLPKGLF 181 G+V+VIAPWNYPYLTA NTIVPAL+AGN+VILKHAAQTLLVGERFQ A D++GLPKG+F Sbjct: 124 LGVVMVIAPWNYPYLTAVNTIVPALMAGNSVILKHAAQTLLVGERFQQAFDKIGLPKGVF 183 Query: 182 RTLTLDHGVTRELISSRSVDHVNFX------RAVERAAAGTFISLGLELGGKDPAYVRPD 235 + + L+H T +L+ S +DHVNF RA+E+AAAGTF++LGLELGGKDPAYV PD Sbjct: 184 QNVVLNHAQTEKLLGSGKIDHVNFTGSVAGGRAIEKAAAGTFMTLGLELGGKDPAYVLPD 243 Query: 236 ADFDFAVEQLVDGAFYNSGQCCCGIERIYVHERIYGSFVDAFADLTARYRLGNPLSRDTT 295 A D AV LVDGAFYNSGQCCCGIER+YVHE++Y FV+ F T Y +GNPL + TT Sbjct: 244 AKMDHAVANLVDGAFYNSGQCCCGIERVYVHEKVYDEFVEGFIAETKNYVVGNPLDQATT 303 Query: 296 LGPMAATRFADAVRAHIGEAVAKGARPLIDPARFPADKIGTAYLMPQVLVGVDHSMRVMM 355 +GPMA RFAD +R EA+ KGA+ I+ + DK G+ YL P+VL VDH M VM Sbjct: 304 MGPMAQARFADLIREQKAEALRKGAKAHIN-MKVADDKAGSPYLAPEVLTEVDHQMSVMR 362 Query: 356 EESFGPVVGLMKVSSDQEAIGLMNDSPYGLTASVWTEDAAAAERIGDGIATGTMFMNRCD 415 EESFGP+VG+MKV +D+EAI LMNDSPYGLTAS+WT D A IG+ + TGT+FMNRCD Sbjct: 363 EESFGPIVGIMKVRNDEEAIALMNDSPYGLTASIWTRDTEHAVAIGNRVETGTVFMNRCD 422 Query: 416 YVDPALAWTGVKDTGRGAGMSRLGFAALTRPKSFHLR 452 Y+DPAL WTGVKDTG+GAG+S +G+ LTRPKSFHLR Sbjct: 423 YLDPALVWTGVKDTGKGAGLSAIGYDNLTRPKSFHLR 459