BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0104.0087.p (303 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_768024.1| oxidoreductase [Bradyrhizobium japonicum USDA 1... 482 e-134 ref|YP_880193.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacteri... 408 e-112 ref|ZP_05215337.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacte... 408 e-112 ref|ZP_05223609.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacte... 407 e-112 ref|NP_959678.1| hypothetical protein MAP0744c [Mycobacterium av... 407 e-112 >ref|NP_768024.1| oxidoreductase [Bradyrhizobium japonicum USDA 110] dbj|BAC46649.1| bll1384 [Bradyrhizobium japonicum USDA 110] Length = 356 Score = 482 bits (1241), Expect = e-134, Method: Compositional matrix adjust. Identities = 241/288 (83%), Positives = 264/288 (91%) Query: 1 MEIGFIGLGKMGLPMARRLIEAGHKLTVFDTSKDALDRLVALGAVAATSPKDIADRVETV 60 M+IGFIGLG MG PMARRLIEAG++L VFDT K+ +D+LVA GA ATSPKD+AD+VETV Sbjct: 55 MDIGFIGLGNMGFPMARRLIEAGNRLVVFDTRKEVVDKLVARGATPATSPKDVADQVETV 114 Query: 61 MASLPSLQASLEVATGAGGVIEGTRVKRFIDLSTVGSQMAVKIHDLLAKKNIVQIDSPVS 120 MASLPSLQASLEVATG GVIEG+RVKRFIDLSTVGS MA KIH LLAK++IVQID PVS Sbjct: 115 MASLPSLQASLEVATGTNGVIEGSRVKRFIDLSTVGSTMASKIHGLLAKRDIVQIDCPVS 174 Query: 121 GGVSGAEKGTLAVMVSGPRADFELVKSALDVIGKVFFIGTKPGSGQTMKLANNFLSATAM 180 GGV GAEKGTLAVMVSGP+A+FEL+K ALDVIGKVFFIG KPG+ QTMKLANNFLSATA+ Sbjct: 175 GGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQTMKLANNFLSATAI 234 Query: 181 VATSEAVVMGVKSGLDPAVMIDVINAGSGLNTASRDKFPRSVLPRSFDFGFATGLMVKDV 240 VATSEAVVMGVK+GLDPAVMIDVINAGSG+NTASRDKFPRSVLPR+FDFGFATGLMVKDV Sbjct: 235 VATSEAVVMGVKAGLDPAVMIDVINAGSGMNTASRDKFPRSVLPRTFDFGFATGLMVKDV 294 Query: 241 RLAVEEMRSLGLSMEVAEAVGRLWEVIIRDEGPDSDFTAAIKPIEKAA 288 RLA+EEM+ LGLSMEVA+AVGRLWE +I EG DSDFTAAIKPIEK A Sbjct: 295 RLALEEMKQLGLSMEVADAVGRLWETVISAEGADSDFTAAIKPIEKKA 342 >ref|YP_880193.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacterium avium 104] gb|ABK67410.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacterium avium 104] Length = 297 Score = 408 bits (1049), Expect = e-112, Method: Compositional matrix adjust. Identities = 192/293 (65%), Positives = 244/293 (83%) Query: 1 MEIGFIGLGKMGLPMARRLIEAGHKLTVFDTSKDALDRLVALGAVAATSPKDIADRVETV 60 M IGFIGLG MG PMA RLI H + FD+ ++AL+RLVA GA A+SPK++AD ETV Sbjct: 1 MTIGFIGLGNMGFPMASRLIREQHDVVAFDSRREALERLVAAGARPASSPKEVADGAETV 60 Query: 61 MASLPSLQASLEVATGAGGVIEGTRVKRFIDLSTVGSQMAVKIHDLLAKKNIVQIDSPVS 120 +ASLP+ ASLEVATG GVIEG RVKR++DLSTVGS+ A++IHDLLA++NIV IDSPVS Sbjct: 61 LASLPTPGASLEVATGTAGVIEGARVKRYVDLSTVGSRTAMRIHDLLARRNIVAIDSPVS 120 Query: 121 GGVSGAEKGTLAVMVSGPRADFELVKSALDVIGKVFFIGTKPGSGQTMKLANNFLSATAM 180 GGV GAE+GTLA+MVSGPR +F+++++ L+ +G+ F++G KPG+ QTMKLANN L+A + Sbjct: 121 GGVGGAEQGTLALMVSGPRGEFDVIRTTLEALGRPFYVGDKPGAAQTMKLANNILAANVL 180 Query: 181 VATSEAVVMGVKSGLDPAVMIDVINAGSGLNTASRDKFPRSVLPRSFDFGFATGLMVKDV 240 AT+E VVMGVK+GLDPAVMI+V+NAGSG +ASRDKFPR++LPRSFD+GFATGLMVKDV Sbjct: 181 AATAEVVVMGVKAGLDPAVMIEVLNAGSGATSASRDKFPRAILPRSFDYGFATGLMVKDV 240 Query: 241 RLAVEEMRSLGLSMEVAEAVGRLWEVIIRDEGPDSDFTAAIKPIEKAAGVIVG 293 RL ++E ++LG+ EVAE + RLWE R+EGP++DFT IKP+E+AAGV VG Sbjct: 241 RLYLDEAKALGVPAEVAETIARLWETAAREEGPEADFTTVIKPLERAAGVTVG 293 >ref|ZP_05215337.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] Length = 297 Score = 408 bits (1049), Expect = e-112, Method: Compositional matrix adjust. Identities = 192/293 (65%), Positives = 244/293 (83%) Query: 1 MEIGFIGLGKMGLPMARRLIEAGHKLTVFDTSKDALDRLVALGAVAATSPKDIADRVETV 60 M IGFIGLG MG PMA RLI H + FD+ ++AL+RLVA GA A+SPK++AD ETV Sbjct: 1 MTIGFIGLGNMGFPMASRLIREQHDVVAFDSRREALERLVAAGARPASSPKEVADGAETV 60 Query: 61 MASLPSLQASLEVATGAGGVIEGTRVKRFIDLSTVGSQMAVKIHDLLAKKNIVQIDSPVS 120 +ASLP+ ASLEVATG GVIEG RVKR++DLSTVGS+ A++IHDLLA++NIV IDSPVS Sbjct: 61 LASLPTPGASLEVATGTAGVIEGARVKRYVDLSTVGSRTAMRIHDLLARRNIVAIDSPVS 120 Query: 121 GGVSGAEKGTLAVMVSGPRADFELVKSALDVIGKVFFIGTKPGSGQTMKLANNFLSATAM 180 GGV GAE+GTLA+MVSGPR +F+++++ L+ +G+ F++G KPG+ QTMKLANN L+A + Sbjct: 121 GGVGGAEQGTLALMVSGPRGEFDVIRTTLEALGRPFYVGDKPGAAQTMKLANNMLAANVL 180 Query: 181 VATSEAVVMGVKSGLDPAVMIDVINAGSGLNTASRDKFPRSVLPRSFDFGFATGLMVKDV 240 AT+E VVMGVK+GLDPAVMI+V+NAGSG +ASRDKFPR++LPRSFD+GFATGLMVKDV Sbjct: 181 AATAEVVVMGVKAGLDPAVMIEVLNAGSGATSASRDKFPRAILPRSFDYGFATGLMVKDV 240 Query: 241 RLAVEEMRSLGLSMEVAEAVGRLWEVIIRDEGPDSDFTAAIKPIEKAAGVIVG 293 RL ++E ++LG+ EVAE + RLWE R+EGP++DFT IKP+E+AAGV VG Sbjct: 241 RLYLDEAKALGVPAEVAETIARLWETAAREEGPEADFTTVIKPLERAAGVTVG 293 >ref|ZP_05223609.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length = 297 Score = 407 bits (1047), Expect = e-112, Method: Compositional matrix adjust. Identities = 194/293 (66%), Positives = 239/293 (81%) Query: 1 MEIGFIGLGKMGLPMARRLIEAGHKLTVFDTSKDALDRLVALGAVAATSPKDIADRVETV 60 MEIGFIGLG MG PMA RLI+ H + FDT AL R+VALGA A+SP ++ADR +TV Sbjct: 1 MEIGFIGLGNMGFPMACRLIQEKHDVVAFDTRSTALARVVALGARPASSPHEVADRADTV 60 Query: 61 MASLPSLQASLEVATGAGGVIEGTRVKRFIDLSTVGSQMAVKIHDLLAKKNIVQIDSPVS 120 +ASLP+ SLEVATG GVIEG R+KR++DLSTVGSQMA++IH LLA++NI +IDSPVS Sbjct: 61 LASLPTPGVSLEVATGPAGVIEGKRIKRYVDLSTVGSQMAMRIHGLLAERNIARIDSPVS 120 Query: 121 GGVSGAEKGTLAVMVSGPRADFELVKSALDVIGKVFFIGTKPGSGQTMKLANNFLSATAM 180 GGV GAEKGTLA+MVSGPR +FE +++ LD +G+ ++G PGS QTMKLANN L+A + Sbjct: 121 GGVGGAEKGTLALMVSGPRGEFEAIRTVLDALGRPVYVGDTPGSAQTMKLANNILAANVL 180 Query: 181 VATSEAVVMGVKSGLDPAVMIDVINAGSGLNTASRDKFPRSVLPRSFDFGFATGLMVKDV 240 AT+E VVMGVK+GLDP VMI+V+NAGSG +ASRDKFPR++LPR+FD+GFATGLMVKDV Sbjct: 181 AATAEVVVMGVKAGLDPGVMIEVLNAGSGATSASRDKFPRAILPRTFDYGFATGLMVKDV 240 Query: 241 RLAVEEMRSLGLSMEVAEAVGRLWEVIIRDEGPDSDFTAAIKPIEKAAGVIVG 293 L ++E ++LG+ EVAEA RLWE + RDEGPDSDFT IKP+E+AAGV VG Sbjct: 241 HLYLDEAKALGVPAEVAEATARLWEAVARDEGPDSDFTTVIKPLERAAGVTVG 293 >ref|NP_959678.1| hypothetical protein MAP0744c [Mycobacterium avium subsp. paratuberculosis K-10] gb|AAS03061.1| hypothetical protein MAP_0744c [Mycobacterium avium subsp. paratuberculosis K-10] Length = 297 Score = 407 bits (1047), Expect = e-112, Method: Compositional matrix adjust. Identities = 192/293 (65%), Positives = 243/293 (82%) Query: 1 MEIGFIGLGKMGLPMARRLIEAGHKLTVFDTSKDALDRLVALGAVAATSPKDIADRVETV 60 M IGFIGLG MG PMA RLI H + FD+ ++AL+RLVA GA A+SPK++AD ETV Sbjct: 1 MTIGFIGLGNMGFPMASRLIREQHDVVAFDSRREALERLVAAGARPASSPKEVADGAETV 60 Query: 61 MASLPSLQASLEVATGAGGVIEGTRVKRFIDLSTVGSQMAVKIHDLLAKKNIVQIDSPVS 120 +ASLP+ ASLEVATG GVIEG RVKR++DLSTVGS+ A++IHDLLA++NIV IDSPVS Sbjct: 61 LASLPTPGASLEVATGTAGVIEGARVKRYVDLSTVGSRTAMRIHDLLARRNIVAIDSPVS 120 Query: 121 GGVSGAEKGTLAVMVSGPRADFELVKSALDVIGKVFFIGTKPGSGQTMKLANNFLSATAM 180 GGV GAE+GTLA+MVSGPR +F+++++ L+ +G+ F++G KPG+ QTMKLANN L+A + Sbjct: 121 GGVGGAEQGTLALMVSGPRGEFDVIRTTLEALGRPFYVGDKPGAAQTMKLANNILAANVL 180 Query: 181 VATSEAVVMGVKSGLDPAVMIDVINAGSGLNTASRDKFPRSVLPRSFDFGFATGLMVKDV 240 AT+E VVMGVK+GLDPAVMI+V+NAGSG +ASRDKFPR++LPRSFD+GFATGLMVKDV Sbjct: 181 AATAEVVVMGVKAGLDPAVMIEVLNAGSGATSASRDKFPRAILPRSFDYGFATGLMVKDV 240 Query: 241 RLAVEEMRSLGLSMEVAEAVGRLWEVIIRDEGPDSDFTAAIKPIEKAAGVIVG 293 RL ++E +LG+ EVAE + RLWE R+EGP++DFT IKP+E+AAGV VG Sbjct: 241 RLYLDEASALGVPAEVAETIARLWETTAREEGPEADFTTVIKPLERAAGVTVG 293