BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0082.0050.p (253 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001923774.1| beta-lactamase domain-containing protein [Me... 297 1e-78 ref|YP_001772649.1| beta-lactamase domain-containing protein [Me... 296 1e-78 ref|ZP_00051396.2| COG1237: Metal-dependent hydrolases of the be... 293 1e-77 ref|YP_002965229.1| metallo-hydrolase/oxidoreductase precursor, ... 292 4e-77 ref|YP_001641376.1| beta-lactamase domain-containing protein [Me... 290 1e-76 >ref|YP_001923774.1| beta-lactamase domain-containing protein [Methylobacterium populi BJ001] gb|ACB79239.1| beta-lactamase domain protein [Methylobacterium populi BJ001] Length = 372 Score = 297 bits (760), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 147/234 (62%), Positives = 183/234 (78%), Gaps = 5/234 (2%) Query: 1 MTHDLARRDFLKGSAAIAGAAAAGAFSCVEIASAAPIEVPTVDKLSIRVLVDSSFDLFFK 60 MT L RR FLK SAA+A +AA FSC+E+A AAP+ VPTVD LS+RVL+DS+ D F K Sbjct: 1 MTEALDRRGFLKLSAALAAGSAA-GFSCIEVARAAPVAVPTVDTLSLRVLIDSAHDQFLK 59 Query: 61 PKQAGGVTIASPP---RSADYQKSLHNEWGLSLWLESEAKGAQRTLMLDYGYTPEVLLNN 117 P GV + PP R ADY+K LHN+WGLSL+ ES+A RT++LD+GY+PE LLNN Sbjct: 60 PATVQGV-LHQPPGNGRGADYRKVLHNQWGLSLFAESKAGEEARTILLDFGYSPEALLNN 118 Query: 118 MALVGVDPAKLDALIVSHGHYDHFGGLNGFLDKFRDKLPADVKLYAGGEDNFCHRVSATP 177 + ++ VDP K+DALIVSHGH+DH+GGL GFLDK+RD L ++KLYAGGEDNFCHR+S + Sbjct: 119 IEILKVDPTKIDALIVSHGHHDHYGGLTGFLDKYRDALSPELKLYAGGEDNFCHRLSPSG 178 Query: 178 TKGQFSDFGTLDRRQLAAQRVTTVLCETPTVIAGHAFTTGKITRRSIERVLPQT 231 +GQF+DFG LDRR+L A+R+ TVLCE PTV+AGHAFTTG+I R S ER+LP T Sbjct: 179 VQGQFTDFGQLDRRELTARRIATVLCEAPTVVAGHAFTTGQIKRTSAERILPNT 232 >ref|YP_001772649.1| beta-lactamase domain-containing protein [Methylobacterium sp. 4-46] gb|ACA20215.1| beta-lactamase domain protein [Methylobacterium sp. 4-46] Length = 372 Score = 296 bits (759), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 149/234 (63%), Positives = 187/234 (79%), Gaps = 5/234 (2%) Query: 1 MTHDLARRDFLKGSAAIAGAAAAGAFSCVEIASAAPIEVPTVDKLSIRVLVDSSFDLFFK 60 M LARRDFLK SAA+ +AAA F+C+EIA+AAPIE+PTVD L++RVLVDS+ D F K Sbjct: 1 MMRSLARRDFLKASAALGASAAA-GFACLEIATAAPIEIPTVDALTLRVLVDSAHDQFLK 59 Query: 61 PKQAGGVTIASPP---RSADYQKSLHNEWGLSLWLESEAKGAQRTLMLDYGYTPEVLLNN 117 P GV + PP R +DY+K LHN+WGLSL+ ES+ + +T++LD+GYTPE LLNN Sbjct: 60 PSTVQGV-VHQPPGGGRGSDYRKVLHNQWGLSLFAESQRRDETKTILLDFGYTPEALLNN 118 Query: 118 MALVGVDPAKLDALIVSHGHYDHFGGLNGFLDKFRDKLPADVKLYAGGEDNFCHRVSATP 177 + ++ +DP+K DALIVSHGH+DH+GGL GFLD++R L DVKL+AGGEDNFCHR+ + Sbjct: 119 IEILKLDPSKADALIVSHGHHDHYGGLIGFLDRYRASLSPDVKLFAGGEDNFCHRLVPSG 178 Query: 178 TKGQFSDFGTLDRRQLAAQRVTTVLCETPTVIAGHAFTTGKITRRSIERVLPQT 231 T GQF+DFG LDRR+LAA+ +TTVLCE PTVIAGHAFTTG+I RRS+ERVLP T Sbjct: 179 TAGQFTDFGLLDRRELAARHITTVLCEAPTVIAGHAFTTGQIKRRSLERVLPNT 232 >ref|ZP_00051396.2| COG1237: Metal-dependent hydrolases of the beta-lactamase superfamily II [Magnetospirillum magnetotacticum MS-1] Length = 372 Score = 293 bits (751), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 142/228 (62%), Positives = 177/228 (77%), Gaps = 5/228 (2%) Query: 7 RRDFLKGSAAIAGAAAAGAFSCVEIASAAPIEVPTVDKLSIRVLVDSSFDLFFKPKQAGG 66 RR FLK +A A +A FSCVE+A AAP+ +P VD LS+RVL+DS+ D F KP G Sbjct: 7 RRGFLK-ISAALAAGSAAGFSCVEVARAAPLAIPAVDSLSLRVLIDSAHDQFLKPSTVQG 65 Query: 67 VTIASPP---RSADYQKSLHNEWGLSLWLESEAKGAQRTLMLDYGYTPEVLLNNMALVGV 123 V + PP R ADY+K LHN+WGLSL+ ES+A RT++LD+GY+PE LLNN+ ++ V Sbjct: 66 V-LHQPPGNGRGADYRKVLHNQWGLSLFAESKAGEDARTILLDFGYSPEALLNNIEILKV 124 Query: 124 DPAKLDALIVSHGHYDHFGGLNGFLDKFRDKLPADVKLYAGGEDNFCHRVSATPTKGQFS 183 DP K+DALIVSHGH+DH+GGL GFLD++RD L D+KLYAGGEDNFCHR+S + +GQF+ Sbjct: 125 DPTKVDALIVSHGHHDHYGGLTGFLDRYRDALSPDLKLYAGGEDNFCHRLSPSGVQGQFT 184 Query: 184 DFGTLDRRQLAAQRVTTVLCETPTVIAGHAFTTGKITRRSIERVLPQT 231 DFG LDRR+LAA+R+ TVLCE PTV+AGHAFTTG I R SIER+LP T Sbjct: 185 DFGQLDRRELAARRIATVLCEAPTVVAGHAFTTGPIQRNSIERILPNT 232 >ref|YP_002965229.1| metallo-hydrolase/oxidoreductase precursor, exonuclease precursor (tat pathway signal) [methylobacterium extorquens AM1] gb|ACS41952.1| putative metallo-hydrolase/oxidoreductase precursor, putative exonuclease precursor (tat pathway signal) [Methylobacterium extorquens AM1] Length = 372 Score = 292 bits (747), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 149/234 (63%), Positives = 182/234 (77%), Gaps = 5/234 (2%) Query: 1 MTHDLARRDFLKGSAAIAGAAAAGAFSCVEIASAAPIEVPTVDKLSIRVLVDSSFDLFFK 60 M + RRDFL+GSA A AAA FSC+EIA+AAPI VPTVD+LS+RVL+DS+ D F K Sbjct: 1 MAGTIDRRDFLRGSALFAAGAAA-GFSCIEIANAAPIAVPTVDRLSLRVLIDSAHDQFLK 59 Query: 61 PKQAGGVTIASPP---RSADYQKSLHNEWGLSLWLESEAKGAQRTLMLDYGYTPEVLLNN 117 P GV + PP R ADY+K LHN+WGLSL+ ES RT++LD+GY+PE LLNN Sbjct: 60 PATVQGV-LHQPPGNGRGADYRKVLHNQWGLSLFAESWRAEEARTILLDFGYSPEALLNN 118 Query: 118 MALVGVDPAKLDALIVSHGHYDHFGGLNGFLDKFRDKLPADVKLYAGGEDNFCHRVSATP 177 + ++ VDP K+DALIVSHGH+DH+GGL GFLDK+R L D+KLYAGGEDNFCHR S + Sbjct: 119 IEILKVDPTKIDALIVSHGHHDHYGGLTGFLDKYRSALAPDLKLYAGGEDNFCHRHSPSG 178 Query: 178 TKGQFSDFGTLDRRQLAAQRVTTVLCETPTVIAGHAFTTGKITRRSIERVLPQT 231 GQF+DFG LDRR+L AQ+++TVLCETPTV+AGHAFTTG+I R SIER+LP T Sbjct: 179 VPGQFTDFGQLDRRELTAQKISTVLCETPTVVAGHAFTTGQIKRASIERILPNT 232 >ref|YP_001641376.1| beta-lactamase domain-containing protein [Methylobacterium extorquens PA1] gb|ABY32305.1| beta-lactamase domain protein [Methylobacterium extorquens PA1] Length = 372 Score = 290 bits (743), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 149/234 (63%), Positives = 181/234 (77%), Gaps = 5/234 (2%) Query: 1 MTHDLARRDFLKGSAAIAGAAAAGAFSCVEIASAAPIEVPTVDKLSIRVLVDSSFDLFFK 60 M + RR FL+GSA A AAA FSC+EIA+AAPI VPTVDKLS+RVL+DS+ D F K Sbjct: 1 MAGTIDRRGFLRGSALFAAGAAA-GFSCIEIANAAPIAVPTVDKLSLRVLIDSAHDQFLK 59 Query: 61 PKQAGGVTIASPP---RSADYQKSLHNEWGLSLWLESEAKGAQRTLMLDYGYTPEVLLNN 117 P GV + PP R ADY+K LHN+WGLSL+ ES RT++LD+GY+PE LLNN Sbjct: 60 PATVQGV-LHQPPGNGRGADYRKVLHNQWGLSLFAESWRAEEARTILLDFGYSPEALLNN 118 Query: 118 MALVGVDPAKLDALIVSHGHYDHFGGLNGFLDKFRDKLPADVKLYAGGEDNFCHRVSATP 177 + ++ VDP K+DALIVSHGH+DH+GGL GFLDK+R L D+KLYAGGEDNFCHR S + Sbjct: 119 IEILKVDPTKIDALIVSHGHHDHYGGLTGFLDKYRSALAPDLKLYAGGEDNFCHRHSPSG 178 Query: 178 TKGQFSDFGTLDRRQLAAQRVTTVLCETPTVIAGHAFTTGKITRRSIERVLPQT 231 GQF+DFG LDRR+L AQ+++TVLCETPTV+AGHAFTTG+I R SIER+LP T Sbjct: 179 VPGQFTDFGQLDRRELTAQKISTVLCETPTVVAGHAFTTGQIKRASIERILPNT 232