BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0074.0004.p (485 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_773247.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia... 712 0.0 ref|YP_485608.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia... 683 0.0 ref|YP_001207551.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-... 680 0.0 ref|YP_570524.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia... 674 0.0 ref|YP_317660.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia... 670 0.0 >ref|NP_773247.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Bradyrhizobium japonicum USDA 110] sp|Q89FU2.1|MURE_BRAJA RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=UDP-MurNAc-tripeptide synthetase; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase dbj|BAC51872.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase [Bradyrhizobium japonicum USDA 110] Length = 485 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/483 (78%), Positives = 428/483 (88%), Gaps = 2/483 (0%) Query: 1 MRLRDLFDADATIDPSADTIVVGGLAVDSRAVKPGDLFFALAGSRTDGARFVDAAIAAGA 60 M+LRDL DA I+P+ + V G+A+DSR V+PGDLFFALAGS+TDGARF+DAA+AAGA Sbjct: 1 MKLRDLIGNDAAIEPAVAALEVTGVALDSRVVRPGDLFFALAGSKTDGARFIDAAVAAGA 60 Query: 61 VAVASDHLPQGHARAPFVITPNPRRALARAAAKFFPRQPATIAAVTGTSGKTSVAAFTRQ 120 VA+ DH P G + PF+ NPRRALA AAA+FFP QPATIAAVTGTSGKTSVAAFTRQ Sbjct: 61 VAIVGDHAPDG-CKVPFIAVANPRRALALAAARFFPAQPATIAAVTGTSGKTSVAAFTRQ 119 Query: 121 IWQRLGHSSASIGTIGLVSDKRTVYGSLTTPDPIALHRQLDEIVSDGVTHLAFEASSHGL 180 IW+RLGH+SASIGTIGLVS KRTVYGSLTTPDPIALHRQ+DEI +GVTHLAFEASSHGL Sbjct: 120 IWERLGHASASIGTIGLVSPKRTVYGSLTTPDPIALHRQMDEIAREGVTHLAFEASSHGL 179 Query: 181 DQYRLDGVRIAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVAPGGAAVISADHDCSG 240 DQYRLDGVR++AGGFTNLSRDHMDYHP VAHYL AKLRLFR+LV PGGAAVISADHDCS Sbjct: 180 DQYRLDGVRVSAGGFTNLSRDHMDYHPTVAHYLAAKLRLFRELVPPGGAAVISADHDCSA 239 Query: 241 EVIDAARSRGLRIIAVGRNAD-AGDGIKLLDAAIEGFAQRLLIEHRGRKHAIRLPLVGEF 299 E IDAA++RGLR++AVGRN D AG+GI+L + ++GF+Q+L +EHRG+++ + LPL GEF Sbjct: 240 EAIDAAKARGLRVMAVGRNGDGAGEGIRLTEVGVDGFSQKLTVEHRGKRYVVLLPLAGEF 299 Query: 300 QIENALVAAGLAIGTGSAADDVFGCLEHLEGAKGRLEFVGEHNGAPIFVDYAHKPDALAK 359 Q+ENALV+AGLAIGTGS A +VF LEHLEGAKGRLE VGE NGAPIFVDYAHKPDALAK Sbjct: 300 QVENALVSAGLAIGTGSDAANVFASLEHLEGAKGRLERVGERNGAPIFVDYAHKPDALAK 359 Query: 360 ALQALRPYARRKLVVIFGAGGDRDAGKRPIMGAIAAENADQVIVTDDNPRSEKPEAIRAA 419 ALQALRPYA+R+LVV+FGAGGDRDAGKRPIMG IAAENAD VI+TDDNPRSE+PEAIRAA Sbjct: 360 ALQALRPYAKRRLVVVFGAGGDRDAGKRPIMGEIAAENADGVIITDDNPRSEQPEAIRAA 419 Query: 420 IMATAKGAREIGDRAAAIRAGIAGLAPGDALVVAGKGHEVGQIVGNTTLPFSDHEAVASA 479 I+ATAKGAREIGDRAAAIRA I L GDAL++AGKGHE GQIVG+ LPFSDHEAVA+A Sbjct: 420 ILATAKGAREIGDRAAAIRAAIEELEQGDALLIAGKGHETGQIVGSEVLPFSDHEAVAAA 479 Query: 480 LAA 482 LA+ Sbjct: 480 LAS 482 >ref|YP_485608.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodopseudomonas palustris HaA2] gb|ABD06697.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodopseudomonas palustris HaA2] Length = 485 Score = 683 bits (1763), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/474 (78%), Positives = 405/474 (85%) Query: 1 MRLRDLFDADATIDPSADTIVVGGLAVDSRAVKPGDLFFALAGSRTDGARFVDAAIAAGA 60 M+LRDLF D I A + VGGLAVDSRAVKPGD+FFALAG++TDGARFV AAI AGA Sbjct: 1 MKLRDLFSDDTAITVQAAALDVGGLAVDSRAVKPGDVFFALAGAKTDGARFVAAAIEAGA 60 Query: 61 VAVASDHLPQGHARAPFVITPNPRRALARAAAKFFPRQPATIAAVTGTSGKTSVAAFTRQ 120 VAVA DH P G PFV NPRRALA AAA+ FP+QP TIAAVTGTSGKTSVAAFTRQ Sbjct: 61 VAVAGDHPPAGDLAVPFVRLTNPRRALALAAARMFPQQPQTIAAVTGTSGKTSVAAFTRQ 120 Query: 121 IWQRLGHSSASIGTIGLVSDKRTVYGSLTTPDPIALHRQLDEIVSDGVTHLAFEASSHGL 180 IWQRLGH+SASIGTIGLV+ R+VYGSLTTPDPIALHR LD I +GVTHLA EASSHGL Sbjct: 121 IWQRLGHASASIGTIGLVTPTRSVYGSLTTPDPIALHRSLDAIAREGVTHLALEASSHGL 180 Query: 181 DQYRLDGVRIAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVAPGGAAVISADHDCSG 240 DQ+RLDGVR+AAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLV GGAAVISADHDCS Sbjct: 181 DQFRLDGVRVAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVVDGGAAVISADHDCSA 240 Query: 241 EVIDAARSRGLRIIAVGRNADAGDGIKLLDAAIEGFAQRLLIEHRGRKHAIRLPLVGEFQ 300 EVIDAAR+RGLR+I+VGRN DAG GI+L+ AA++GFAQRL ++H GR + + LPLVGEFQ Sbjct: 241 EVIDAARARGLRLISVGRNGDAGAGIRLIAAAVDGFAQRLTLDHAGRNYQVHLPLVGEFQ 300 Query: 301 IENALVAAGLAIGTGSAADDVFGCLEHLEGAKGRLEFVGEHNGAPIFVDYAHKPDALAKA 360 IENALVAAGL IGTG VF L+HLEGA GRLE VGE NGAP+FVDYAHKPDALAK+ Sbjct: 301 IENALVAAGLVIGTGGDPAAVFAALDHLEGAPGRLELVGERNGAPVFVDYAHKPDALAKS 360 Query: 361 LQALRPYARRKLVVIFGAGGDRDAGKRPIMGAIAAENADQVIVTDDNPRSEKPEAIRAAI 420 LQALRPYA+RKLVV+FGAGGDRDAGKRP+MGAIAAE+AD VIVTDDNPR E P IRAAI Sbjct: 361 LQALRPYAKRKLVVVFGAGGDRDAGKRPLMGAIAAESADAVIVTDDNPRREDPATIRAAI 420 Query: 421 MATAKGAREIGDRAAAIRAGIAGLAPGDALVVAGKGHEVGQIVGNTTLPFSDHE 474 +A A GAREIGDRA AIR I L PGDALV+AGKGHE GQIVG+T LPFSDHE Sbjct: 421 LAAAPGAREIGDRAEAIRTAIGELQPGDALVIAGKGHETGQIVGDTVLPFSDHE 474 >ref|YP_001207551.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Bradyrhizobium sp. ORS 278] emb|CAL79334.1| UDP-N-acetylmuramoylalanyl-D-glutamate 2, 6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase) [Bradyrhizobium sp. ORS 278] Length = 486 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/482 (75%), Positives = 408/482 (84%), Gaps = 1/482 (0%) Query: 1 MRLRDLFDADATIDPSADTIVVGGLAVDSRAVKPGDLFFALAGSRTDGARFVDAAIAAGA 60 M+L DL A +DP + V GLA DSRAV+PGDLFFAL+G++TDG RF+ AA+AAGA Sbjct: 1 MKLHDLLGDQAGLDPRVAAVEVSGLAADSRAVRPGDLFFALSGTKTDGTRFIAAAVAAGA 60 Query: 61 VAVASDHLPQGHARAPFVITPNPRRALARAAAKFFPRQPATIAAVTGTSGKTSVAAFTRQ 120 +AVA P G PFV PNPRRALA AA++ FPRQPATIAAVTGTSGKTSVAAFTRQ Sbjct: 61 IAVAGHEAPAGDLPVPFVSLPNPRRALALAASRVFPRQPATIAAVTGTSGKTSVAAFTRQ 120 Query: 121 IWQRLGHSSASIGTIGLVSDKRTVYGSLTTPDPIALHRQLDEIVSDGVTHLAFEASSHGL 180 IWQ LGH++ASIGT+GL+SDKRTVYGSLTTPDPIALHRQ+DEI DGVTHLAFEASSHGL Sbjct: 121 IWQSLGHNAASIGTVGLISDKRTVYGSLTTPDPIALHRQIDEITQDGVTHLAFEASSHGL 180 Query: 181 DQYRLDGVRIAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVAPGGAAVISADHDCSG 240 DQYRLDGVR++AGGFTNLSRDHMDYHPD+ HYLNAKLRLFRDLV PGG AVISADH+CS Sbjct: 181 DQYRLDGVRVSAGGFTNLSRDHMDYHPDLVHYLNAKLRLFRDLVPPGGPAVISADHECSA 240 Query: 241 EVIDAARSRGLRIIAVGRNAD-AGDGIKLLDAAIEGFAQRLLIEHRGRKHAIRLPLVGEF 299 EVI AA +RGLR++ VG + + AG GI+L+ AA++GFAQ+L ++H GR +RLPLVG F Sbjct: 241 EVIAAADARGLRLMTVGTHGNGAGAGIRLVAAAVDGFAQQLELQHCGRITFLRLPLVGAF 300 Query: 300 QIENALVAAGLAIGTGSAADDVFGCLEHLEGAKGRLEFVGEHNGAPIFVDYAHKPDALAK 359 QIENALVAAGLAIGTGS VF LE LEGAKGRLE VGEHNGAPIF+DYAHKPDALAK Sbjct: 301 QIENALVAAGLAIGTGSDPQAVFEALEKLEGAKGRLELVGEHNGAPIFIDYAHKPDALAK 360 Query: 360 ALQALRPYARRKLVVIFGAGGDRDAGKRPIMGAIAAENADQVIVTDDNPRSEKPEAIRAA 419 AL ALRPYA+RKLVV+FGAGGDRD+GKRP+MG IAA AD+VIVTDDNPRSE P AIRAA Sbjct: 361 ALHALRPYAQRKLVVVFGAGGDRDSGKRPLMGEIAAAGADRVIVTDDNPRSENPAAIRAA 420 Query: 420 IMATAKGAREIGDRAAAIRAGIAGLAPGDALVVAGKGHEVGQIVGNTTLPFSDHEAVASA 479 I+A A GAREIGDRA AIR I+ L PGDALV+AGKGHE GQI+G+T L FSDHEAVA A Sbjct: 421 ILAAAPGAREIGDRAEAIRVAISELQPGDALVIAGKGHETGQIIGDTVLHFSDHEAVADA 480 Query: 480 LA 481 LA Sbjct: 481 LA 482 >ref|YP_570524.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodopseudomonas palustris BisB5] gb|ABE40623.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodopseudomonas palustris BisB5] Length = 490 Score = 674 bits (1740), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/486 (77%), Positives = 416/486 (85%), Gaps = 5/486 (1%) Query: 1 MRLRDLFDADATIDPS-----ADTIVVGGLAVDSRAVKPGDLFFALAGSRTDGARFVDAA 55 M+LRDLF DA ID A + VGGLAVDSRAVKPGDLFFALAG++TDGARF+ AA Sbjct: 1 MKLRDLFSDDAPIDAQGSPRGAADLDVGGLAVDSRAVKPGDLFFALAGAKTDGARFIAAA 60 Query: 56 IAAGAVAVASDHLPQGHARAPFVITPNPRRALARAAAKFFPRQPATIAAVTGTSGKTSVA 115 IAAGAVAVA DH P G PFV NPRRALA AAA+F+ RQP TIAAVTGTSGKTSVA Sbjct: 61 IAAGAVAVAGDHAPDGELAVPFVPLGNPRRALALAAARFYSRQPRTIAAVTGTSGKTSVA 120 Query: 116 AFTRQIWQRLGHSSASIGTIGLVSDKRTVYGSLTTPDPIALHRQLDEIVSDGVTHLAFEA 175 AFTR IWQRLGH++ASIGTIGLV+ R+VYGSLTTPDPIALHR LDEI +GVTHLA EA Sbjct: 121 AFTRHIWQRLGHAAASIGTIGLVTPTRSVYGSLTTPDPIALHRSLDEIAGEGVTHLALEA 180 Query: 176 SSHGLDQYRLDGVRIAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVAPGGAAVISAD 235 SSHGLDQ+RLDGVR+AAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLV GGAAVISAD Sbjct: 181 SSHGLDQFRLDGVRVAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVIDGGAAVISAD 240 Query: 236 HDCSGEVIDAARSRGLRIIAVGRNADAGDGIKLLDAAIEGFAQRLLIEHRGRKHAIRLPL 295 HDCS +VIDAAR+RGLR+I VGRN DAG+GI+L++A+I+GFAQ+L IEH GR+ A+ LPL Sbjct: 241 HDCSAQVIDAARARGLRLITVGRNGDAGEGIRLIEASIDGFAQKLTIEHAGRRTAVHLPL 300 Query: 296 VGEFQIENALVAAGLAIGTGSAADDVFGCLEHLEGAKGRLEFVGEHNGAPIFVDYAHKPD 355 VGEFQIENALVAAGL IG G F L+HLEGA GRL+FVGE GAP+FVDYAHKPD Sbjct: 301 VGEFQIENALVAAGLVIGAGGDPAAAFAALDHLEGAPGRLDFVGERRGAPVFVDYAHKPD 360 Query: 356 ALAKALQALRPYARRKLVVIFGAGGDRDAGKRPIMGAIAAENADQVIVTDDNPRSEKPEA 415 ALAKALQALRPYA+RKLVV+FGAGGDRDAGKRP+MGAIAA NAD +IVTDDNPRSE P A Sbjct: 361 ALAKALQALRPYAKRKLVVVFGAGGDRDAGKRPLMGAIAAGNADSIIVTDDNPRSEDPAA 420 Query: 416 IRAAIMATAKGAREIGDRAAAIRAGIAGLAPGDALVVAGKGHEVGQIVGNTTLPFSDHEA 475 IRAAI+A A GAREIGDRA AIR IA LAPGDAL++AGKGHE GQIV +T LPFSDHEA Sbjct: 421 IRAAILAAAPGAREIGDRAEAIRTAIAALAPGDALLIAGKGHETGQIVRDTVLPFSDHEA 480 Query: 476 VASALA 481 A+AL+ Sbjct: 481 AAAALS 486 >ref|YP_317660.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Nitrobacter winogradskyi Nb-255] gb|ABA04308.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Nitrobacter winogradskyi Nb-255] Length = 485 Score = 670 bits (1728), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/483 (73%), Positives = 405/483 (83%), Gaps = 2/483 (0%) Query: 1 MRLRDLFDADATIDPSADTIVVGGLAVDSRAVKPGDLFFALAGSRTDGARFVDAAIAAGA 60 M+LR+LF DAT+D A + V GLA DSRAVKPGDLFFALAGS+TDGARF+DAAIA+GA Sbjct: 1 MKLRELFGDDATMDAPAGELAVTGLAADSRAVKPGDLFFALAGSKTDGARFIDAAIASGA 60 Query: 61 VAVASDHLPQGHARAPFVITPNPRRALARAAAKFFPRQPATIAAVTGTSGKTSVAAFTRQ 120 VAVA DH P R PF+ TPNPRRALA AAAKF+PRQPATIAAVTGTSGKTSVAAFTRQ Sbjct: 61 VAVAGDHAP-ARGRVPFIATPNPRRALALAAAKFYPRQPATIAAVTGTSGKTSVAAFTRQ 119 Query: 121 IWQRLGHSSASIGTIGLVSDKRTVYGSLTTPDPIALHRQLDEIVSDGVTHLAFEASSHGL 180 IWQRLG+ SASIGT+G+V+ R VYGS+TTPDPI LHR+LD++ +GVTHLA EASSHGL Sbjct: 120 IWQRLGYLSASIGTVGVVAPSRAVYGSVTTPDPIELHRELDQLAGEGVTHLALEASSHGL 179 Query: 181 DQYRLDGVRIAAGGFTNLSRDHMDYHPDVAHYLNAKLRLFRDLVAPGGAAVISADHDCSG 240 DQYR+DGVR+ A GFTNLSRDHMDYHP VAHYL KLRLFRDLV G AVI ADHDCS Sbjct: 180 DQYRVDGVRVRAAGFTNLSRDHMDYHPTVAHYLETKLRLFRDLVESDGIAVICADHDCSD 239 Query: 241 EVIDAARSRGLRIIAVGRNAD-AGDGIKLLDAAIEGFAQRLLIEHRGRKHAIRLPLVGEF 299 VI+AA +R + ++ VGR D A GI+L++AAI+GFAQR+ +EH GR+ IRLPLVGEF Sbjct: 240 TVIEAAGARNVPVMRVGRRGDGARMGIRLVEAAIDGFAQRVTLEHAGRERVIRLPLVGEF 299 Query: 300 QIENALVAAGLAIGTGSAADDVFGCLEHLEGAKGRLEFVGEHNGAPIFVDYAHKPDALAK 359 QIENALV+AGL IGTG D F LEHLEGA+GR+E +GE NGA +FVDYAHKPDALAK Sbjct: 300 QIENALVSAGLVIGTGGDVDQAFAALEHLEGARGRIERIGERNGAQVFVDYAHKPDALAK 359 Query: 360 ALQALRPYARRKLVVIFGAGGDRDAGKRPIMGAIAAENADQVIVTDDNPRSEKPEAIRAA 419 ALQALRPYA+RKLVV+FGAGGDRDAGKRP+MGAIAA+NAD VIVTDDNPRSE P AIRAA Sbjct: 360 ALQALRPYAKRKLVVVFGAGGDRDAGKRPLMGAIAADNADVVIVTDDNPRSEDPAAIRAA 419 Query: 420 IMATAKGAREIGDRAAAIRAGIAGLAPGDALVVAGKGHEVGQIVGNTTLPFSDHEAVASA 479 I+A A GAREIGDRA AI IAGL GDAL++AGKGHE GQIVG+ LPFSDHEA ++A Sbjct: 420 ILAAAPGAREIGDRAEAIGTAIAGLQSGDALLIAGKGHETGQIVGDRVLPFSDHEAASAA 479 Query: 480 LAA 482 L + Sbjct: 480 LTS 482