BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0072.0077.p (436 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001208846.1| GDP-mannose 6-dehydrogenase [Bradyrhizobium ... 627 e-177 ref|YP_002501013.1| nucleotide sugar dehydrogenase [Methylobacte... 449 e-124 ref|YP_003166125.1| nucleotide sugar dehydrogenase [Candidatus A... 428 e-118 ref|YP_001269741.1| GDP-mannose 6-dehydrogenase [Pseudomonas put... 427 e-117 ref|NP_743448.1| GDP-mannose 6-dehydrogenase [Pseudomonas putida... 426 e-117 >ref|YP_001208846.1| GDP-mannose 6-dehydrogenase [Bradyrhizobium sp. ORS 278] emb|CAL80631.1| GDP-mannose 6-dehydrogenase (GMD) [Bradyrhizobium sp. ORS 278] Length = 436 Score = 627 bits (1617), Expect = e-177, Method: Compositional matrix adjust. Identities = 310/436 (71%), Positives = 365/436 (83%) Query: 1 MNVSIFGLGYVGTVCAACFTELGHQIIGVDKNVAKVDLIREGRSPVVEPGISDKVARAVA 60 MN+SIFGLGYVGTVCAAC ELGH IIGVDK AKV+LI+ G+SPV+EPGIS+KVA AVA Sbjct: 1 MNISIFGLGYVGTVCAACLAELGHHIIGVDKAGAKVELIQAGQSPVIEPGISEKVAAAVA 60 Query: 61 TGQLTATTDATEAIVNSDISMVCVGTPSSGNGNLDLTAIRQVAIEIGRGLRAKNAPHTVT 120 G+LTA+TDAT AI +DISM+CVGTPS+ +G+LDLTAIRQVA EIG GLR K H V Sbjct: 61 AGRLTASTDATAAIAATDISMICVGTPSAASGDLDLTAIRQVAAEIGHGLREKPTSHLVV 120 Query: 121 IRSTVLPGTTRGTVGPLIEEASGNRIGRDFDLAFNPEFLREGSAIADFNAPSKTVVGAFN 180 IRSTVLPGT++ V PLIEEASG + G DF+++FNPEFLREG AIADFN+PSKTVVGA Sbjct: 121 IRSTVLPGTSQRIVVPLIEEASGKKAGTDFEISFNPEFLREGCAIADFNSPSKTVVGADR 180 Query: 181 QETADRVMALYKDLPGAKITPPVETAELVKYVDNSWHALKVSFANEIGTIAKTLGIDGRD 240 ETA R+++LY+ LPGAKI +ETAEL KY+DN+WHALKV+FANE+G IAKTL ID R+ Sbjct: 181 SETAARILSLYEQLPGAKIAASIETAELAKYIDNTWHALKVAFANEVGVIAKTLDIDSRE 240 Query: 241 VMNIFMQDTRLNISPAYLRPGFAFGGSCLPKDVKALKHLAHSRGLSTPVLESILPSNDMI 300 V++IF+QDTRLNIS AYLRPGFAFGGSCLPKD+KALKHLA GLS PV+E++LPSNDM+ Sbjct: 241 VIDIFLQDTRLNISAAYLRPGFAFGGSCLPKDIKALKHLAGRHGLSVPVIENVLPSNDMV 300 Query: 301 MSRGADWILSHEGRRIAFLGISFKAGTDDVRDSPFVRLVKSLRGERRDIRIYDPNVQLSQ 360 MSRG DWIL+ GR++AFLGISFKAGTDDVR+SPFV LV L R++R+YDPNV+LSQ Sbjct: 301 MSRGVDWILAQPGRKVAFLGISFKAGTDDVRESPFVLLVNGLLSRDREVRVYDPNVRLSQ 360 Query: 361 LIGANREFLMRNPELVGLLNDDVTATIEWADIIVLTTADPRFVAALTATRPDQVVLELSE 420 LIGANR+FLMRN ++ +L DDV TI+WADIIVLTT DPRF+ AL +TR DQ VLEL+E Sbjct: 361 LIGANRDFLMRNRQIADILVDDVAETIDWADIIVLTTNDPRFIDALRSTRADQTVLELTE 420 Query: 421 IGLPEQVRAKVSGFHW 436 LP V+A V GFHW Sbjct: 421 ARLPADVQATVKGFHW 436 >ref|YP_002501013.1| nucleotide sugar dehydrogenase [Methylobacterium nodulans ORS 2060] gb|ACL60710.1| nucleotide sugar dehydrogenase [Methylobacterium nodulans ORS 2060] Length = 437 Score = 449 bits (1155), Expect = e-124, Method: Compositional matrix adjust. Identities = 214/437 (48%), Positives = 295/437 (67%), Gaps = 1/437 (0%) Query: 1 MNVSIFGLGYVGTVCAACFTELGHQIIGVDKNVAKVDLIREGRSPVVEPGISDKVARAVA 60 MNVS+FGLGYVGTVC+AC +GH ++GVD N KVDL+ G+ P+VE +++ VA AVA Sbjct: 1 MNVSVFGLGYVGTVCSACLAHMGHHVVGVDLNRTKVDLLARGQPPIVERDVAEYVADAVA 60 Query: 61 TGQLTATTDATEAIVNSDISMVCVGTPSSGNGNLDLTAIRQVAIEIGRGLRAKNAPHTVT 120 G L AT D EA +++D+S++CVGTPS NG+LD +A+ VA +IG + KN+ H++ Sbjct: 61 AGNLRATMDVEEAALDTDLSLICVGTPSRANGSLDTSAVETVARQIGHAIAGKNSYHSIV 120 Query: 121 IRSTVLPGTTRGTVGPLIEEASGNRIGRDFDLAFNPEFLREGSAIADFNAPSKTVVGAFN 180 +RSTVLPGT R V P++E+ G ++G F LA NPEF+REG+A+ADF P KTV+G + Sbjct: 121 VRSTVLPGTVRSRVLPILEQEIGGQVGEAFGLASNPEFMREGTAVADFYDPPKTVIGEVD 180 Query: 181 QETADRVMALYKDLPGAKITPPVETAELVKYVDNSWHALKVSFANEIGTIAKTLGIDGRD 240 ETADR+++LY LPG +E AE+ KY DN WHALKV+F NEIG I K GID Sbjct: 181 AETADRLVSLYDGLPGPTFRTSLEIAEMAKYADNVWHALKVTFGNEIGAICKRAGIDSHQ 240 Query: 241 VMNIFMQDTRLNISPAYLRPGFAFGGSCLPKDVKALKHLAHSRGLSTPVLESILPSNDMI 300 +M +F D +LNIS AYL+PGFAFGGSCLPKD +AL H A + L PV+ SI SN Sbjct: 241 LMEMFCADEKLNISKAYLKPGFAFGGSCLPKDTRALAHHAVAHDLDLPVIASIGRSNRQQ 300 Query: 301 MSRGADWILSHEGRRIAFLGISFKAGTDDVRDSPFVRLVKSLRGERRDIRIYDPNVQLSQ 360 + RG +WIL+ +RIAFLG SFKAGTDD+R+SP++ +++ L G+ +RI+D NV+L++ Sbjct: 301 IERGTEWILATGAKRIAFLGFSFKAGTDDLRESPYLEIIERLIGKGCQVRIFDRNVELAK 360 Query: 361 LIGANREFLMRN-PELVGLLNDDVTATIEWADIIVLTTADPRFVAALTATRPDQVVLELS 419 L GANR +L P + L+ + + A+I+V+T P + RP Q VL+ + Sbjct: 361 LTGANRSYLYGVIPHVADLMVTSIEEAVAEAEIVVVTAKSPEYRPIAELARPGQRVLDFA 420 Query: 420 EIGLPEQVRAKVSGFHW 436 + E + ++ GF W Sbjct: 421 RLPEAEALESQYDGFLW 437 >ref|YP_003166125.1| nucleotide sugar dehydrogenase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gb|ACV34196.1| nucleotide sugar dehydrogenase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length = 437 Score = 428 bits (1101), Expect = e-118, Method: Compositional matrix adjust. Identities = 203/438 (46%), Positives = 300/438 (68%), Gaps = 3/438 (0%) Query: 1 MNVSIFGLGYVGTVCAACFTELGHQIIGVDKNVAKVDLIREGRSPVVEPGISDKVARAVA 60 M +SIFG+GYVG V A C GH++IGVD N KVDLI G++P++E I + VA VA Sbjct: 1 MKISIFGMGYVGAVSAGCLANDGHEVIGVDPNQTKVDLINSGQTPIIEKDIGEMVASGVA 60 Query: 61 TGQLTATTDATEAIVNSDISMVCVGTPSSGNGNLDLTAIRQVAIEIGRGLRAKNAPHTVT 120 +L AT++ EA+++SDIS++CVGTPS NGNLDL+ +R+V EIG +R K H V Sbjct: 61 AKRLRATSNVHEAVLDSDISLICVGTPSQLNGNLDLSFVRRVCEEIGSAIREKAGFHVVV 120 Query: 121 IRSTVLPGTTRGTVGPLIEEASGNRIGRDFDLAFNPEFLREGSAIADFNAPSKTVVGAFN 180 RST+LPG+ R V P++E+ SG GRDF + NPEFLREG+A+ D+ P KTV+G + Sbjct: 121 ARSTMLPGSMRSVVIPMLEQYSGKTAGRDFGVCNNPEFLREGTAVYDYYNPPKTVIGETD 180 Query: 181 QETADRVMALYKDLPGAKITPPVETAELVKYVDNSWHALKVSFANEIGTIAKTLGIDGRD 240 + D ++ LY+ + + VETAE+VKY DN+WHA+KV+FANEIG ++K+LGIDG Sbjct: 181 AQAGDVLVKLYEKMGAPLVRTDVETAEMVKYTDNNWHAVKVAFANEIGNLSKSLGIDGHK 240 Query: 241 VMNIFMQDTRLNISPAYLRPGFAFGGSCLPKDVKALKHLAHSRGLSTPVLESILPSNDMI 300 VM IF +DT+LN+SP Y++PGFAFGGSCLPKDV+AL + A + L P+L S++PSN Sbjct: 241 VMEIFCKDTKLNLSPYYMKPGFAFGGSCLPKDVRALTYKARTLDLDLPLLNSLMPSNQRQ 300 Query: 301 MSRGADWILSHEGRRIAFLGISFKAGTDDVRDSPFVRLVKSLRGERRDIRIYDPNVQLSQ 360 + +G + + ++ +R+ LG +FKAGTDD+R+SP V +V+SL G+ ++++YD NV L+ Sbjct: 301 VQKGLEMVTAYGKKRVGILGFAFKAGTDDLRESPLVEVVESLIGKGYEMKLYDRNVNLAA 360 Query: 361 LIGANREFLMRN-PELVGLLNDDVTATIEWADIIVLTTADPRFVAALTATRPDQVVLELS 419 L GANR++++ + P + L+ + + + +A++I++ + F L +P QVV++L Sbjct: 361 LTGANRDYILNHIPHISKLMVESMEDVVSFAEVIIIGNSAQEFRNILEQIKPGQVVVDLV 420 Query: 420 EIGLPEQVRA-KVSGFHW 436 I +P + A + G W Sbjct: 421 RI-VPNKSEAGRYDGICW 437 >ref|YP_001269741.1| GDP-mannose 6-dehydrogenase [Pseudomonas putida F1] gb|ABQ80557.1| GDP-mannose 6-dehydrogenase [Pseudomonas putida F1] gb|ADR61849.1| GDP-mannose 6-dehydrogenase [Pseudomonas putida BIRD-1] Length = 438 Score = 427 bits (1097), Expect = e-117, Method: Compositional matrix adjust. Identities = 211/438 (48%), Positives = 292/438 (66%), Gaps = 2/438 (0%) Query: 1 MNVSIFGLGYVGTVCAACFTELGHQIIGVDKNVAKVDLIREGRSPVVEPGISDKVARAVA 60 M +SIFGLGYVG VCA C T GH++IGVD + K+DLI +G+SP+VEPG+ + + +A Sbjct: 1 MRISIFGLGYVGAVCAGCLTARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGIA 60 Query: 61 TGQLTATTDATEAIVNSDISMVCVGTPSSGNGNLDLTAIRQVAIEIGRGLRAKNAPHTVT 120 G+L TTD EAI SD+SM+CVGTPS NG+L L I V EIG LR HT+ Sbjct: 61 NGRLRGTTDFAEAIRASDVSMICVGTPSKKNGDLGLEYIESVCREIGYVLRDTTRRHTIV 120 Query: 121 IRSTVLPGTTRGTVGPLIEEASGNRIGRDFDLAFNPEFLREGSAIADFNAPSKTVVGAFN 180 +RSTVLPGT + V P++E+ SG + G DF +A NPEFLRE +AI D++ P TV+G + Sbjct: 121 VRSTVLPGTVKNVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDQPPMTVIGELD 180 Query: 181 QETADRVMALYKDLPGAKITPPVETAELVKYVDNSWHALKVSFANEIGTIAKTLGIDGRD 240 + D + ALY++L I P+E AE++KY N WHA KV+FANEIG IAK +G+DGR+ Sbjct: 181 SASGDILQALYEELDAPVIRKPIEVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGRE 240 Query: 241 VMNIFMQDTRLNISPAYLRPGFAFGGSCLPKDVKALKHLAHSRGLSTPVLESILPSNDMI 300 VM++ QD LN+S Y+RPGFAFGGSCLPKDV+AL + A S + P+L+S++ SN+ Sbjct: 241 VMDVVCQDKVLNLSQYYMRPGFAFGGSCLPKDVRALTYRAASLDVRAPLLDSLMRSNESQ 300 Query: 301 MSRGADWILSHEGRRIAFLGISFKAGTDDVRDSPFVRLVKSLRGERRDIRIYDPNVQLSQ 360 + + I +H+ R++A LG+SFKAGTDD+R+SP V L + L G+ + IYD NVQ ++ Sbjct: 301 VQNAFELIEAHDKRKVALLGLSFKAGTDDLRESPLVELAERLIGKGYQLDIYDENVQYAR 360 Query: 361 LIGANREFL-MRNPELVGLLNDDVTATIEWADIIVLTTADPRFVA-ALTATRPDQVVLEL 418 + GAN++++ + P + LLN ++ I+ ADIIVL D +F A AL A QV+ + Sbjct: 361 VHGANKDYIESKIPHVSSLLNANLQQVIDNADIIVLGNRDEQFRALALQAPAGKQVIDLV 420 Query: 419 SEIGLPEQVRAKVSGFHW 436 + P A+ G W Sbjct: 421 GFMNKPTSTTARTEGICW 438 >ref|NP_743448.1| GDP-mannose 6-dehydrogenase [Pseudomonas putida KT2440] sp|Q88NC4.1|ALGD_PSEPK RecName: Full=GDP-mannose 6-dehydrogenase; Short=GMD gb|AAN66912.1|AE016319_8 GDP-mannose 6-dehydrogenase [Pseudomonas putida KT2440] Length = 438 Score = 426 bits (1096), Expect = e-117, Method: Compositional matrix adjust. Identities = 211/438 (48%), Positives = 292/438 (66%), Gaps = 2/438 (0%) Query: 1 MNVSIFGLGYVGTVCAACFTELGHQIIGVDKNVAKVDLIREGRSPVVEPGISDKVARAVA 60 M +SIFGLGYVG VCA C T GH++IGVD + K+DLI +G+SP+VEPG+ + + +A Sbjct: 1 MRISIFGLGYVGAVCAGCLTARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGIA 60 Query: 61 TGQLTATTDATEAIVNSDISMVCVGTPSSGNGNLDLTAIRQVAIEIGRGLRAKNAPHTVT 120 G+L TTD EAI SD+SM+CVGTPS NG+L L I V EIG LR HT+ Sbjct: 61 NGRLRGTTDFAEAIRASDVSMICVGTPSKKNGDLGLEYIESVCREIGYVLRDTTRRHTIV 120 Query: 121 IRSTVLPGTTRGTVGPLIEEASGNRIGRDFDLAFNPEFLREGSAIADFNAPSKTVVGAFN 180 +RSTVLPGT + V P++E+ SG + G DF +A NPEFLRE +AI D++ P TV+G + Sbjct: 121 VRSTVLPGTVKNVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDQPPMTVIGELD 180 Query: 181 QETADRVMALYKDLPGAKITPPVETAELVKYVDNSWHALKVSFANEIGTIAKTLGIDGRD 240 + D + ALY++L I P+E AE++KY N WHA KV+FANEIG IAK +G+DGR+ Sbjct: 181 SASGDILQALYEELDAPIIRKPIEVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGRE 240 Query: 241 VMNIFMQDTRLNISPAYLRPGFAFGGSCLPKDVKALKHLAHSRGLSTPVLESILPSNDMI 300 VM++ QD LN+S Y+RPGFAFGGSCLPKDV+AL + A S + P+L+S++ SN+ Sbjct: 241 VMDVVCQDKVLNLSQYYMRPGFAFGGSCLPKDVRALTYRAASLDVRAPLLDSLMRSNESQ 300 Query: 301 MSRGADWILSHEGRRIAFLGISFKAGTDDVRDSPFVRLVKSLRGERRDIRIYDPNVQLSQ 360 + + I +H+ R++A LG+SFKAGTDD+R+SP V L + L G+ + IYD NVQ ++ Sbjct: 301 VQNAFELIEAHDKRKVALLGLSFKAGTDDLRESPLVELAERLIGKGYQLDIYDENVQYAR 360 Query: 361 LIGANREFL-MRNPELVGLLNDDVTATIEWADIIVLTTADPRFVA-ALTATRPDQVVLEL 418 + GAN++++ + P + LLN ++ I+ ADIIVL D +F A AL A QV+ + Sbjct: 361 VHGANKDYIESKIPHVSSLLNANLQQVIDNADIIVLGNRDEQFRALALQAPAGKQVIDLV 420 Query: 419 SEIGLPEQVRAKVSGFHW 436 + P A+ G W Sbjct: 421 GFMNKPTSTTARTEGICW 438