BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0230.p (335 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_487828.1| D-isomer specific 2-hydroxyacid dehydrogenase, ... 519 e-145 ref|YP_371723.1| D-isomer specific 2-hydroxyacid dehydrogenase [... 510 e-142 ref|YP_571198.1| D-isomer specific 2-hydroxyacid dehydrogenase [... 508 e-142 gb|EFV85689.1| D-isomer specific 2-hydroxyacid dehydrogenase [Ac... 496 e-138 gb|EGP47738.1| D-isomer specific 2-hydroxyacid dehydrogenase [Ac... 486 e-135 >ref|YP_487828.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [Rhodopseudomonas palustris HaA2] gb|ABD08917.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [Rhodopseudomonas palustris HaA2] Length = 331 Score = 519 bits (1337), Expect = e-145, Method: Compositional matrix adjust. Identities = 247/319 (77%), Positives = 276/319 (86%) Query: 1 MKISILDDYFDTLRTLDCYRKLDGYDVKIWNDHVQDVDALAERLRDTDALVLIRERTQIR 60 MK++ILDDYFDTLRTL+C+ +L G+DV ++NDHVQD DALA RLRDT+ALVLIRERTQIR Sbjct: 1 MKVAILDDYFDTLRTLNCFGRLQGHDVTVFNDHVQDTDALASRLRDTEALVLIRERTQIR 60 Query: 61 TPLLERLPKLKLISQRSVYPHIDIDTCTRLGIIVSSSQHADTPSYATAEFTWGMILAAMR 120 LLE+LP+LKLISQR VYPHID+D CTRLGI+VSS+ A PSYA AE TWG++L AMR Sbjct: 61 AALLEKLPRLKLISQRGVYPHIDVDACTRLGIVVSSNMSAGAPSYAAAELTWGLVLGAMR 120 Query: 121 AIPQQMAALKAGKWQIGVGHTLRGKTLGIYGYGRIGAVVAGYGKAFGMNVLVWAREPAMA 180 IPQQMAALKAG WQIGVGHTLR KTLGIYGYGRIG VVAGYG+AFGM VLVWAREP +A Sbjct: 121 QIPQQMAALKAGVWQIGVGHTLRDKTLGIYGYGRIGRVVAGYGRAFGMTVLVWAREPNLA 180 Query: 181 KARADGYETSASKADFFARCDVLSLHMRLVDATRGIVKAEDLARMKQTALIVNTSRAPLI 240 +ARADGY+ + SK D FA DVLSLHMRL+DATRGIV DLARMK TAL+VNTSRA LI Sbjct: 181 EARADGYQIAGSKEDLFAHSDVLSLHMRLIDATRGIVTRADLARMKPTALLVNTSRAGLI 240 Query: 241 EPGALVNALRAGRPGMAAIDVYEKEPLRDPADPLLNMDNVVCTPHLGYVSRDEYEIQFTD 300 E GALV ALRAGRPGMAAIDV++ EPLRDP DPLL MDNVV TPH+GYVSRDEYE+QF D Sbjct: 241 EQGALVAALRAGRPGMAAIDVFDTEPLRDPQDPLLAMDNVVATPHIGYVSRDEYELQFGD 300 Query: 301 IFDQILAYTAGTPTNVVNP 319 IF+QI+AY AG P NVVNP Sbjct: 301 IFEQIVAYAAGEPINVVNP 319 >ref|YP_371723.1| D-isomer specific 2-hydroxyacid dehydrogenase [Burkholderia sp. 383] gb|ABB11079.1| D-isomer specific 2-hydroxyacid dehydrogenase [Burkholderia sp. 383] Length = 400 Score = 510 bits (1313), Expect = e-142, Method: Compositional matrix adjust. Identities = 245/323 (75%), Positives = 275/323 (85%) Query: 1 MKISILDDYFDTLRTLDCYRKLDGYDVKIWNDHVQDVDALAERLRDTDALVLIRERTQIR 60 M I+ILDDYFDTLRTL C+RKLDG+ V IWNDHVQDVDALAERLRDTD LVLIRERTQIR Sbjct: 1 MNITILDDYFDTLRTLPCFRKLDGHTVTIWNDHVQDVDALAERLRDTDVLVLIRERTQIR 60 Query: 61 TPLLERLPKLKLISQRSVYPHIDIDTCTRLGIIVSSSQHADTPSYATAEFTWGMILAAMR 120 PL+ RLPKL+LISQRSVYPHIDID CT G+IVSS+QH+ TPSYA AE TWG++LAAMR Sbjct: 61 APLIARLPKLRLISQRSVYPHIDIDACTAHGVIVSSNQHSGTPSYAAAELTWGLVLAAMR 120 Query: 121 AIPQQMAALKAGKWQIGVGHTLRGKTLGIYGYGRIGAVVAGYGKAFGMNVLVWAREPAMA 180 IPQQM AL+AG WQIGVG TLRG+TLGIYGYGRIGA VA YG AFGMNVLVWARE ++ Sbjct: 121 QIPQQMRALQAGDWQIGVGRTLRGRTLGIYGYGRIGAEVARYGAAFGMNVLVWAREASLQ 180 Query: 181 KARADGYETSASKADFFARCDVLSLHMRLVDATRGIVKAEDLARMKQTALIVNTSRAPLI 240 +AR DG+ T+ K FF CDVLSLHMRLV ATRGIV AEDL RMK AL+VNTSRA L+ Sbjct: 181 RARDDGWRTAPDKHTFFDTCDVLSLHMRLVPATRGIVTAEDLGRMKPGALLVNTSRAGLV 240 Query: 241 EPGALVNALRAGRPGMAAIDVYEKEPLRDPADPLLNMDNVVCTPHLGYVSRDEYEIQFTD 300 PGAL AL+AGRPGMAA+DVYE EPLRDP PLL++ NVVCTPH+GYV+ DEYE QF+D Sbjct: 241 APGALEAALQAGRPGMAAVDVYETEPLRDPRHPLLSLPNVVCTPHIGYVTEDEYETQFSD 300 Query: 301 IFDQILAYTAGTPTNVVNPDVLA 323 +FDQI++Y AG P +VVNPDVLA Sbjct: 301 VFDQIVSYAAGQPIHVVNPDVLA 323 >ref|YP_571198.1| D-isomer specific 2-hydroxyacid dehydrogenase [Rhodopseudomonas palustris BisB5] gb|ABE41297.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [Rhodopseudomonas palustris BisB5] Length = 327 Score = 508 bits (1309), Expect = e-142, Method: Compositional matrix adjust. Identities = 250/324 (77%), Positives = 286/324 (88%) Query: 1 MKISILDDYFDTLRTLDCYRKLDGYDVKIWNDHVQDVDALAERLRDTDALVLIRERTQIR 60 MKI+ILDDYFDTLRTL C+ KL G+DV ++NDH+QD DALAERL++T+ALVLIRERTQIR Sbjct: 1 MKIAILDDYFDTLRTLPCFAKLAGHDVSVFNDHLQDTDALAERLKETEALVLIRERTQIR 60 Query: 61 TPLLERLPKLKLISQRSVYPHIDIDTCTRLGIIVSSSQHADTPSYATAEFTWGMILAAMR 120 LLE+LPKLKLISQRSVYPHIDID CTRLGI+VSS+ HA TPSYA AE TWG++LAAMR Sbjct: 61 AALLEKLPKLKLISQRSVYPHIDIDACTRLGIVVSSNMHAGTPSYAAAELTWGLVLAAMR 120 Query: 121 AIPQQMAALKAGKWQIGVGHTLRGKTLGIYGYGRIGAVVAGYGKAFGMNVLVWAREPAMA 180 IPQQ ALKAG WQIGVGHTLR KTLGI+GYGRIG+VVAGYG+AFGM VLVWAREP++A Sbjct: 121 QIPQQATALKAGIWQIGVGHTLRDKTLGIFGYGRIGSVVAGYGRAFGMTVLVWAREPSLA 180 Query: 181 KARADGYETSASKADFFARCDVLSLHMRLVDATRGIVKAEDLARMKQTALIVNTSRAPLI 240 +ARADG++ + SK +FFA+ DVLSLH+RLVDATR IV DLARMK AL+VNTSRA LI Sbjct: 181 QARADGHQIAGSKEEFFAQSDVLSLHIRLVDATRAIVTRSDLARMKPGALLVNTSRAGLI 240 Query: 241 EPGALVNALRAGRPGMAAIDVYEKEPLRDPADPLLNMDNVVCTPHLGYVSRDEYEIQFTD 300 EPGALV ALRAGRPGMAAIDV++ EPLRDP+DPLL MDNVV TPH+GYVSRDEYE+QF++ Sbjct: 241 EPGALVEALRAGRPGMAAIDVFDAEPLRDPSDPLLKMDNVVATPHIGYVSRDEYELQFSE 300 Query: 301 IFDQILAYTAGTPTNVVNPDVLAH 324 IFDQI+AY AG P NVVNP V +H Sbjct: 301 IFDQIVAYAAGEPINVVNPAVTSH 324 >gb|EFV85689.1| D-isomer specific 2-hydroxyacid dehydrogenase [Achromobacter xylosoxidans C54] Length = 323 Score = 496 bits (1277), Expect = e-138, Method: Compositional matrix adjust. Identities = 235/323 (72%), Positives = 270/323 (83%) Query: 1 MKISILDDYFDTLRTLDCYRKLDGYDVKIWNDHVQDVDALAERLRDTDALVLIRERTQIR 60 M I+ILDDYFDTLR L C+RKLDG+ V +WNDHVQDVDALAERLRDT+ALVLIRERTQIR Sbjct: 1 MNITILDDYFDTLRGLPCFRKLDGHAVTVWNDHVQDVDALAERLRDTEALVLIRERTQIR 60 Query: 61 TPLLERLPKLKLISQRSVYPHIDIDTCTRLGIIVSSSQHADTPSYATAEFTWGMILAAMR 120 PL+ RLPKL+LISQRSVYPHID+D CT G+I+SS+QHA TPSYA AE TWG++LA MR Sbjct: 61 APLIARLPKLRLISQRSVYPHIDVDACTAHGVILSSNQHAGTPSYAAAELTWGLVLAGMR 120 Query: 121 AIPQQMAALKAGKWQIGVGHTLRGKTLGIYGYGRIGAVVAGYGKAFGMNVLVWAREPAMA 180 IPQQ+ ALK G WQ G+G TLRG+TLGIYGYGRIGA VA YG AFGM VLVWARE + Sbjct: 121 RIPQQVEALKNGVWQTGMGRTLRGRTLGIYGYGRIGAEVARYGAAFGMRVLVWAREASRQ 180 Query: 181 KARADGYETSASKADFFARCDVLSLHMRLVDATRGIVKAEDLARMKQTALIVNTSRAPLI 240 +AR DG++ + K FF CDVLSLHMRLV TRGIV A DLARMK +AL+VNTSRA LI Sbjct: 181 RARDDGWDVAPDKQAFFEACDVLSLHMRLVPDTRGIVTAADLARMKPSALLVNTSRAGLI 240 Query: 241 EPGALVNALRAGRPGMAAIDVYEKEPLRDPADPLLNMDNVVCTPHLGYVSRDEYEIQFTD 300 EPGALV ALRAGRPGMAA+DV+E EPLRDP DPLL + N +CTPH+GYV+ DEYE QF+D Sbjct: 241 EPGALVQALRAGRPGMAAVDVFETEPLRDPKDPLLQLPNAICTPHIGYVTEDEYETQFSD 300 Query: 301 IFDQILAYTAGTPTNVVNPDVLA 323 +FDQI++Y AG P +V+NP VLA Sbjct: 301 VFDQIVSYAAGKPIHVINPAVLA 323 >gb|EGP47738.1| D-isomer specific 2-hydroxyacid dehydrogenase [Achromobacter xylosoxidans AXX-A] Length = 323 Score = 486 bits (1251), Expect = e-135, Method: Compositional matrix adjust. Identities = 230/323 (71%), Positives = 265/323 (82%) Query: 1 MKISILDDYFDTLRTLDCYRKLDGYDVKIWNDHVQDVDALAERLRDTDALVLIRERTQIR 60 M I+ILDDYFDTLR L C+RKLDG+ V +WNDHVQDVDALAERLRDT+ALVLIRERTQIR Sbjct: 1 MNITILDDYFDTLRGLPCFRKLDGHAVTVWNDHVQDVDALAERLRDTEALVLIRERTQIR 60 Query: 61 TPLLERLPKLKLISQRSVYPHIDIDTCTRLGIIVSSSQHADTPSYATAEFTWGMILAAMR 120 PL+ RLPKL+LISQRSVYPHID+D CT G+I+SS+QHA TPSYA AE TWG++LA MR Sbjct: 61 APLIARLPKLRLISQRSVYPHIDVDACTEHGVILSSNQHAGTPSYAAAELTWGLVLAGMR 120 Query: 121 AIPQQMAALKAGKWQIGVGHTLRGKTLGIYGYGRIGAVVAGYGKAFGMNVLVWAREPAMA 180 IPQ + LK G WQ G+G TLRG+TLGIYGYGRIGA VA YG AFGM VLVWARE + Sbjct: 121 RIPQAVQLLKQGTWQTGMGRTLRGRTLGIYGYGRIGAEVARYGAAFGMKVLVWAREASRQ 180 Query: 181 KARADGYETSASKADFFARCDVLSLHMRLVDATRGIVKAEDLARMKQTALIVNTSRAPLI 240 +AR DG++ + K FF CDVLSLHMRLV TRGIV A DLARMK +AL+VNTSRA LI Sbjct: 181 RARDDGWDVAPDKQAFFETCDVLSLHMRLVPDTRGIVTAADLARMKPSALLVNTSRAGLI 240 Query: 241 EPGALVNALRAGRPGMAAIDVYEKEPLRDPADPLLNMDNVVCTPHLGYVSRDEYEIQFTD 300 EPGALV ALRAGRPG AA+DV+E EP+ DP PLL + N +CTPH+GYV+ DEYE QF+D Sbjct: 241 EPGALVQALRAGRPGAAAVDVFESEPMTDPQHPLLQLPNALCTPHIGYVTEDEYETQFSD 300 Query: 301 IFDQILAYTAGTPTNVVNPDVLA 323 +FDQI+AY AG P +V+NP VLA Sbjct: 301 VFDQIVAYAAGKPIHVINPAVLA 323