BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0058.0007.p (293 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08628881.1| 3-hydroxyisobutyrate dehydrogenase [Bradyrhiz... 346 2e-93 ref|YP_004125020.1| 3-hydroxyisobutyrate dehydrogenase [Alicycli... 332 4e-89 ref|YP_996857.1| 6-phosphogluconate dehydrogenase [Verminephroba... 328 9e-88 ref|YP_002287992.1| 6-phosphogluconate dehydrogenase, NAD-bindin... 327 1e-87 ref|YP_001202345.1| putative oxidoreductase 3-hydroxyisobutyrate... 322 5e-86 >ref|ZP_08628881.1| 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobiaceae bacterium SG-6C] gb|EGP08240.1| 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobiaceae bacterium SG-6C] Length = 294 Score = 346 bits (888), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 173/285 (60%), Positives = 218/285 (76%), Gaps = 1/285 (0%) Query: 7 LGFIGLGVMGEPICRNLVKKSGKRVVVFDLSAEPLQRLRADGAEVAASVADVIKQSDVLF 66 +GFIGLGVMGEP+CRNL +K G+ V FD + +PLQRL A G + AAS+A++ +Q D +F Sbjct: 5 IGFIGLGVMGEPMCRNLARKCGRAVFGFDRADDPLQRLAAAGVKRAASLAELARQCDTIF 64 Query: 67 LCLPSARHVRAVFEG-DGILKNTRSGQIVVDLGTSSVSQTRDFAAQLQAKGAAWVDAPIA 125 + LPS +HV+AV +G D +LK+ + I+VDLGTS V +R+ A AKGA + DAPIA Sbjct: 65 MALPSGKHVQAVCDGEDSLLKHAEARHIIVDLGTSPVEMSRELAKHFAAKGARYADAPIA 124 Query: 126 RTRQAAQDGTLSVMVGAVPALYAAIEPLIRCFATDVTNCGDVGAGQVTKILNNMVLFETV 185 RTRQAA++GTLSVMVGA A ++ ++PLI FATD+T+CGDVGAGQV KILNNMVL +TV Sbjct: 125 RTRQAAEEGTLSVMVGADAATFSELQPLIATFATDITHCGDVGAGQVVKILNNMVLMQTV 184 Query: 186 NALAEAVAVAKHNGVDPKLLLETLSKGSADSFALRNHGMKAIVPGVFPERAFSTEYALKD 245 AL EA+ AK G+D KLL ETL+KGSADSFALRNHGMKA++P +FPERAFS EYA KD Sbjct: 185 VALGEALETAKRAGLDAKLLFETLAKGSADSFALRNHGMKAMLPDMFPERAFSAEYARKD 244 Query: 246 LSYALELAADAGIKIRGAELIGTVLQEAIDKGSKDNYFPVIAKHI 290 +SYAL+LA IK+ GAEL VL E I+ G D Y+PV+A+ I Sbjct: 245 ISYALDLARSVDIKLPGAELADKVLGETIEAGYGDLYWPVLARVI 289 >ref|YP_004125020.1| 3-hydroxyisobutyrate dehydrogenase [Alicycliphilus denitrificans BC] ref|YP_004386244.1| 3-hydroxyisobutyrate dehydrogenase [Alicycliphilus denitrificans K601] gb|ADU98132.1| 3-hydroxyisobutyrate dehydrogenase [Alicycliphilus denitrificans BC] gb|AEB82728.1| 3-hydroxyisobutyrate dehydrogenase [Alicycliphilus denitrificans K601] Length = 297 Score = 332 bits (852), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 169/290 (58%), Positives = 211/290 (72%), Gaps = 1/290 (0%) Query: 2 TDNKPLGFIGLGVMGEPICRNLVKKSGKRVVVFDLSAEPLQRLRADGAEVAASVADVIKQ 61 T ++ +GFIGLGVMGEPICRNL K+G RV+ DL A PLQRL A G + A S A V++ Sbjct: 4 TTSQVIGFIGLGVMGEPICRNLAVKTGARVIAHDLDAAPLQRLAAHGVQAAPSAAAVMQA 63 Query: 62 SDVLFLCLPSARHVRAVFEGDG-ILKNTRSGQIVVDLGTSSVSQTRDFAAQLQAKGAAWV 120 +DV+FL LPS V + DG +L + R+GQ +VDL TS V TR A + A GA +V Sbjct: 64 ADVVFLSLPSGEVVAQLCRQDGGLLASARAGQTIVDLSTSPVDTTRALAGEFAALGARFV 123 Query: 121 DAPIARTRQAAQDGTLSVMVGAVPALYAAIEPLIRCFATDVTNCGDVGAGQVTKILNNMV 180 DAP+ARTR AA+ GTL+VMVGA P ++ A++PLI FA+D+ CG VG GQV KILNNMV Sbjct: 124 DAPVARTRAAAEAGTLAVMVGAAPEVFEAVKPLIATFASDIALCGPVGCGQVLKILNNMV 183 Query: 181 LFETVNALAEAVAVAKHNGVDPKLLLETLSKGSADSFALRNHGMKAIVPGVFPERAFSTE 240 LFETV A++EA A+ + GVDP +L +TLSKGSADSFALRNHGMKA++PG FPERAFS Sbjct: 184 LFETVVAVSEAKAIGEKAGVDPNVLFDTLSKGSADSFALRNHGMKAVLPGEFPERAFSVL 243 Query: 241 YALKDLSYALELAADAGIKIRGAELIGTVLQEAIDKGSKDNYFPVIAKHI 290 YA KDL YAL+LA DAG+ RGA ++ Q+AID G + Y PVI++ I Sbjct: 244 YARKDLKYALQLARDAGVDARGAAVVDAWFQQAIDSGLGEKYHPVISRLI 293 >ref|YP_996857.1| 6-phosphogluconate dehydrogenase [Verminephrobacter eiseniae EF01-2] gb|ABM57839.1| 6-phosphogluconate dehydrogenase, NAD-binding [Verminephrobacter eiseniae EF01-2] Length = 297 Score = 328 bits (840), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 167/287 (58%), Positives = 206/287 (71%), Gaps = 1/287 (0%) Query: 7 LGFIGLGVMGEPICRNLVKKSGKRVVVFDLSAEPLQRLRADGAEVAASVADVIKQSDVLF 66 +GFIGLGVMGEPICRNL +KSG +V+ FDL A PLQRL ADG + S + V+ QSD +F Sbjct: 9 IGFIGLGVMGEPICRNLARKSGAQVLAFDLDAAPLQRLAADGVQGQGSASAVMAQSDTVF 68 Query: 67 LCLPSARHV-RAVFEGDGILKNTRSGQIVVDLGTSSVSQTRDFAAQLQAKGAAWVDAPIA 125 L LPS V + + DG+L + R G IVVDLGTSSV TR AA+ A+ A + DAP+A Sbjct: 69 LSLPSGAIVAQLCRQQDGLLASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVA 128 Query: 126 RTRQAAQDGTLSVMVGAVPALYAAIEPLIRCFATDVTNCGDVGAGQVTKILNNMVLFETV 185 RTR AAQ GTL+VMVGA P L+ IEPLI FA+D+ CG VG GQV KILNNM+LFETV Sbjct: 129 RTRAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMILFETV 188 Query: 186 NALAEAVAVAKHNGVDPKLLLETLSKGSADSFALRNHGMKAIVPGVFPERAFSTEYALKD 245 A++EA A+ + GVD +L +TL+ GSADSFALRNHGMKA++PG FPERAFS YA KD Sbjct: 189 VAISEAKAIGEKAGVDASVLFDTLANGSADSFALRNHGMKAVLPGEFPERAFSVHYARKD 248 Query: 246 LSYALELAADAGIKIRGAELIGTVLQEAIDKGSKDNYFPVIAKHIDR 292 L YAL+LA D G+ R A ++ +AI+ G + Y PVI++ I R Sbjct: 249 LQYALQLADDTGVDARSARVVDRWFAQAIEAGLGEKYHPVISRLIAR 295 >ref|YP_002287992.1| 6-phosphogluconate dehydrogenase, NAD-binding [Oligotropha carboxidovorans OM5] ref|YP_004633898.1| 2-hydroxy-3-oxopropionate reductase GarR [Oligotropha carboxidovorans OM5] gb|ACI92127.1| 6-phosphogluconate dehydrogenase, NAD-binding [Oligotropha carboxidovorans OM5] gb|AEI04033.1| 2-hydroxy-3-oxopropionate reductase GarR [Oligotropha carboxidovorans OM4] gb|AEI07657.1| 2-hydroxy-3-oxopropionate reductase GarR [Oligotropha carboxidovorans OM5] Length = 293 Score = 327 bits (839), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 164/286 (57%), Positives = 209/286 (73%), Gaps = 1/286 (0%) Query: 5 KPLGFIGLGVMGEPICRNLVKKSGKRVVVFDLSAEPLQRLRADGAEVAASVADVIKQSDV 64 K LGFIGLG MGEP+CR+L +KSG +V+++D EPLQRL A G E ++ + + +D+ Sbjct: 4 KTLGFIGLGTMGEPMCRHLAQKSGFKVIIYDRQTEPLQRLSALGVEACETIDLMAQTADI 63 Query: 65 LFLCLPSARHVRAVFEGDGILKNTRSGQIVVDLGTSSVSQTRDFAAQLQAKGAAWVDAPI 124 +FL LPS V V + IL N R+GQIVVDLGTS V+ T A + QAKGA + DAPI Sbjct: 64 IFLALPSGIQVEDVCN-NHILPNARAGQIVVDLGTSPVTLTHALAERFQAKGARYADAPI 122 Query: 125 ARTRQAAQDGTLSVMVGAVPALYAAIEPLIRCFATDVTNCGDVGAGQVTKILNNMVLFET 184 ARTRQAAQ+G LSVMVG YA ++PL+ CFA+DVT+CG+VGAGQV KILNNMVL ET Sbjct: 123 ARTRQAAQEGRLSVMVGCDAETYATLQPLLSCFASDVTHCGNVGAGQVVKILNNMVLVET 182 Query: 185 VNALAEAVAVAKHNGVDPKLLLETLSKGSADSFALRNHGMKAIVPGVFPERAFSTEYALK 244 V AL+EA+ +A+ GVD ++L +TL KGSADSFALRNHGMK+++P FPERAFST+YA K Sbjct: 183 VVALSEAITIARRAGVDGEMLFKTLMKGSADSFALRNHGMKSVLPENFPERAFSTDYARK 242 Query: 245 DLSYALELAADAGIKIRGAELIGTVLQEAIDKGSKDNYFPVIAKHI 290 D+SYAL L G+ + GA +L A +KG + Y+PVI+K I Sbjct: 243 DISYALALGEQFGVPLPGARTADKILASASEKGLGEYYWPVISKVI 288 >ref|YP_001202345.1| putative oxidoreductase 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobium sp. ORS 278] emb|CAL74095.1| putative oxidoreductase; putative 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobium sp. ORS 278] Length = 292 Score = 322 bits (825), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 171/285 (60%), Positives = 215/285 (75%), Gaps = 1/285 (0%) Query: 7 LGFIGLGVMGEPICRNLVKKSGKRVVVFDLSAEPLQRLRADGAEVAASVADVIKQSDVLF 66 +GFIGLGVMGEPICRNL +KSG V+ FD + PLQRL A G AAS+A++ ++++++F Sbjct: 4 IGFIGLGVMGEPICRNLARKSGATVLGFDRADAPLQRLAAVGVIRAASLAELAREAELIF 63 Query: 67 LCLPSARHVRAVFEGD-GILKNTRSGQIVVDLGTSSVSQTRDFAAQLQAKGAAWVDAPIA 125 + LPS +HV++V +GD G+L++ + +VDLGTS V TR+ A AKGAA+ DAPIA Sbjct: 64 MALPSGKHVQSVCDGDDGLLRHAEARHTIVDLGTSPVQATRELATHFAAKGAAFADAPIA 123 Query: 126 RTRQAAQDGTLSVMVGAVPALYAAIEPLIRCFATDVTNCGDVGAGQVTKILNNMVLFETV 185 RTRQAA+DGTLSVMVGA A + + PLI FATD+T+CG VGAGQV KILNNMVL +TV Sbjct: 124 RTRQAAEDGTLSVMVGADAATFERLRPLIAMFATDITHCGGVGAGQVVKILNNMVLMQTV 183 Query: 186 NALAEAVAVAKHNGVDPKLLLETLSKGSADSFALRNHGMKAIVPGVFPERAFSTEYALKD 245 AL EA+ K G+DPKLL ETL+KGSADSFALRNHGMKA++P +PERAFSTEYA KD Sbjct: 184 VALGEALETGKRAGLDPKLLFETLAKGSADSFALRNHGMKAMLPDTYPERAFSTEYARKD 243 Query: 246 LSYALELAADAGIKIRGAELIGTVLQEAIDKGSKDNYFPVIAKHI 290 + YAL+LA I + GAEL L EAI+ G D Y+PV+A+ I Sbjct: 244 IGYALDLARSVQIDLPGAELADRRLGEAIEAGYGDLYWPVLARVI 288