BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0056.0024.p (404 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_774629.1| S-adenosylmethionine synthetase [Bradyrhizobium... 703 0.0 ref|YP_004151683.1| Methionine adenosyltransferase [Thermovibrio... 408 e-112 ref|YP_002128718.1| S-adenosylmethionine synthetase [Phenylobact... 404 e-110 ref|YP_004281503.1| methionine adenosyltransferase [Desulfurobac... 402 e-110 ref|ZP_05099693.1| S-adenosylmethionine synthetase [Roseobacter ... 371 e-100 >ref|NP_774629.1| S-adenosylmethionine synthetase [Bradyrhizobium japonicum USDA 110] dbj|BAC53254.1| S-adenosylmethionine synthetase [Bradyrhizobium japonicum USDA 110] Length = 397 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/397 (88%), Positives = 372/397 (93%) Query: 8 MLALVVSRLDITEEVEVAERKGAGHPDTICDALAETLSRNLCREYVSRFGRVLHHNVDKA 67 M LV+S+LD ++VEV ERKGAGHPDTICDALAETLSRNLCREY+ RFG VLH+NVDKA Sbjct: 1 MFDLVLSQLDNRDDVEVVERKGAGHPDTICDALAETLSRNLCREYLRRFGHVLHYNVDKA 60 Query: 68 LLCGGRAMPAFGGGKVTNPIRIFLAGRAATNVGNERIPVEDITIEGSRAWLKANLHALDA 127 LLCGGRAMP F GGKVT+PIRI LAGRA TNVGNE IPVEDI IEGSRAWLKANLHALDA Sbjct: 61 LLCGGRAMPTFNGGKVTDPIRILLAGRAVTNVGNEAIPVEDIAIEGSRAWLKANLHALDA 120 Query: 128 DRHVRVEALVRQGSQDLQSLFSRGSTQRNPLANDTSFGVGHAPLSALERLVLAIEQGLHG 187 DRHVR+EALV QGSQDLQSLFSRGS ++ PLANDTSFGVGHAPLSALERLVLAIEQG+HG Sbjct: 121 DRHVRIEALVHQGSQDLQSLFSRGSARQIPLANDTSFGVGHAPLSALERLVLAIEQGIHG 180 Query: 188 RDRAHDRLAWGEDIKIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEYARERAT 247 RDRA D AWGEDIKIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEY RERA+ Sbjct: 181 RDRARDHPAWGEDIKIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEYVRERAS 240 Query: 248 EHGFGDCEVAINAADDAASDSVYLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAA 307 EHGF DCEVA+NAADDAASDS+YLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAA Sbjct: 241 EHGFRDCEVAVNAADDAASDSIYLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAA 300 Query: 308 AGKNPVSHVGKIYNVLAKRVAETLVEAIPQVSAAQCLVVSRIGAPVSIPDLIHLRLATKD 367 AGKNPVSHVGKIYN+LAKRVAETLV AIP+VSAAQCL+VSRIGAPVS+PDL+HLRLATKD Sbjct: 301 AGKNPVSHVGKIYNILAKRVAETLVSAIPEVSAAQCLIVSRIGAPVSMPDLVHLRLATKD 360 Query: 368 GVPPEELRERGAEIVSDHLGRIPELVGELVAGEIQLY 404 GVPPEELRERGAEIVSDHLGRIPELVGELVAG +Y Sbjct: 361 GVPPEELRERGAEIVSDHLGRIPELVGELVAGATHVY 397 >ref|YP_004151683.1| Methionine adenosyltransferase [Thermovibrio ammonificans HB-1] gb|ADU97042.1| Methionine adenosyltransferase [Thermovibrio ammonificans HB-1] Length = 398 Score = 408 bits (1049), Expect = e-112, Method: Compositional matrix adjust. Identities = 193/385 (50%), Positives = 268/385 (69%), Gaps = 2/385 (0%) Query: 20 EEVEVAERKGAGHPDTICDALAETLSRNLCREYVSRFGRVLHHNVDKALLCGGRAMPAFG 79 +E+E+ ERKG GHPDTICDALAE LS LC+ Y +FG VLHHNVDK LL GG A+P FG Sbjct: 16 QEIEIVERKGLGHPDTICDALAEKLSAELCKFYYEKFGFVLHHNVDKNLLVGGSALPRFG 75 Query: 80 GGKVTNPIRIFLAGRAATNVGNERIPVEDITIEGSRAWLKANLHALDADRHVRVEALVRQ 139 GG+VT PI IFL+GRA +IPV++I +E ++ WL+ N+HA+D DRHVR+ +R Sbjct: 76 GGEVTEPIEIFLSGRAIKEYKGVKIPVDEIAVESAKEWLRENIHAIDPDRHVRIHTYIRP 135 Query: 140 GSQDLQSLFSRGSTQRNPLANDTSFGVGHAPLSALERLVLAIEQGLHGRDRAHDRLAWGE 199 GS DL ++ R + PL+NDTSFGVG+AP LE +V +E+ L+ ++ GE Sbjct: 136 GSVDLVDIYMRQLKEGVPLSNDTSFGVGYAPFDDLESVVFNVEKKLNSKEIKEKHPEIGE 195 Query: 200 DIKIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEYARERATEHGFGDCEVAIN 259 D+K+M VR GE +K+TIACA + RF+ D++ Y Q++ + + A E A + + EV +N Sbjct: 196 DVKVMGVRVGEKMKITIACAFVDRFVKDVEDYAQKRENVRKIALEVAKQFTNREVEVEVN 255 Query: 260 AADDAASDSVYLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAAAGKNPVSHVGKI 319 DD S +VY+TVTGTSAEAGDDG+VGRGNRVNGLITP+RPMSLEAAAGKNP++HVGK+ Sbjct: 256 TGDDLESGNVYITVTGTSAEAGDDGEVGRGNRVNGLITPYRPMSLEAAAGKNPITHVGKL 315 Query: 320 YNVLAKRVAETLVEAIPQVSAAQCLVVSRIGAPVSIPDLIHLRLATKDGVPPEELRERGA 379 YN+ A +A+ +V I + A +VS+IG PV+ P + +++ +++ P + + + Sbjct: 316 YNITANEIAKGVVSEIEGIEEAYVYMVSQIGKPVNQPLAVDVKVRSQE--PAQAFQGKVE 373 Query: 380 EIVSDHLGRIPELVGELVAGEIQLY 404 EIV +HL ++ E+ LV GEI +Y Sbjct: 374 EIVKEHLAQMKEIWKRLVNGEITVY 398 >ref|YP_002128718.1| S-adenosylmethionine synthetase [Phenylobacterium zucineum HLK1] gb|ACG80143.1| S-adenosylmethionine synthetase [Phenylobacterium zucineum HLK1] Length = 378 Score = 404 bits (1039), Expect = e-110, Method: Compositional matrix adjust. Identities = 214/383 (55%), Positives = 275/383 (71%), Gaps = 5/383 (1%) Query: 22 VEVAERKGAGHPDTICDALAETLSRNLCREYVSRFGRVLHHNVDKALLCGGRAMPAFGGG 81 +EV ERKG GHPD+ICDALAE LSR+LCR Y + FG +LHHNVDKALLC GRA PAFGG Sbjct: 1 MEVVERKGCGHPDSICDALAENLSRDLCRRYQAAFGLILHHNVDKALLCAGRASPAFGGD 60 Query: 82 KVTNPIRIFLAGRAATNVGNERIPVEDITIEGSRAWLKANLHALDADRHVRVEALVRQGS 141 ++ PI I+LAGRAA N ++++ +EG+R WL+ +LHALDA+RHVR+ ++R GS Sbjct: 61 RIAEPIDIYLAGRAAALQKNGGAELKELAVEGARRWLREHLHALDAERHVRIHPVLRPGS 120 Query: 142 QDLQSLFSRGSTQRNPLANDTSFGVGHAPLSALERLVLAIEQGLHGRDRAHDRLAWGEDI 201 +LQ LF GS P ANDTS GVG+APLS LE+LVL +E+ L R AWGED+ Sbjct: 121 AELQGLFE-GSAAAIPRANDTSIGVGYAPLSPLEQLVLDLERALQDAGRP----AWGEDV 175 Query: 202 KIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEYARERATEHGFGDCEVAINAA 261 KIMAVR+G+ V LTI+CA+IG L ++D+YL +KAA+A+ A A E GF C VA+NAA Sbjct: 176 KIMAVRTGQDVTLTISCALIGGELRNLDAYLAEKAAIADLAAASAAERGFRACRVAVNAA 235 Query: 262 DDAASDSVYLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAAAGKNPVSHVGKIYN 321 D + +YLTVTGTSAE+GDDGQVGRGNRV+GLITP RPMSLEAAAGKNPV+HVGKIYN Sbjct: 236 DQPEAGLLYLTVTGTSAESGDDGQVGRGNRVSGLITPGRPMSLEAAAGKNPVTHVGKIYN 295 Query: 322 VLAKRVAETLVEAIPQVSAAQCLVVSRIGAPVSIPDLIHLRLATKDGVPPEELRERGAEI 381 V A+ +A ++V + V A+CL+VS+IGAP++ P + LR G ++R I Sbjct: 296 VAAQEIARSVVAELAPVRRAECLLVSQIGAPITEPAVAELRCELGRGEALRDVRGSIEAI 355 Query: 382 VSDHLGRIPELVGELVAGEIQLY 404 V+ L +P + + V G + L+ Sbjct: 356 VARELAALPGRLEDFVHGRVALF 378 >ref|YP_004281503.1| methionine adenosyltransferase [Desulfurobacterium thermolithotrophum DSM 11699] gb|ADY73444.1| Methionine adenosyltransferase [Desulfurobacterium thermolithotrophum DSM 11699] Length = 398 Score = 402 bits (1033), Expect = e-110, Method: Compositional matrix adjust. Identities = 187/384 (48%), Positives = 265/384 (69%), Gaps = 2/384 (0%) Query: 21 EVEVAERKGAGHPDTICDALAETLSRNLCREYVSRFGRVLHHNVDKALLCGGRAMPAFGG 80 E+E+ ERKG GHPDTICDALAE LS LC+ Y +FG VLHHNVDK LL GG A+P F G Sbjct: 17 EIEIVERKGLGHPDTICDALAEKLSAELCKFYYEKFGFVLHHNVDKNLLVGGSAIPKFMG 76 Query: 81 GKVTNPIRIFLAGRAATNVGNERIPVEDITIEGSRAWLKANLHALDADRHVRVEALVRQG 140 G+VT PI IFL+GRA +IPVE++ +E ++ WL+ N+HA+D ++ VR+ +R G Sbjct: 77 GEVTEPIEIFLSGRAIKEYKGVKIPVEELAVESAKKWLRENIHAIDPEKDVRIYTYIRPG 136 Query: 141 SQDLQSLFSRGSTQRNPLANDTSFGVGHAPLSALERLVLAIEQGLHGRDRAHDRLAWGED 200 S DL ++ R + PL+NDTSFGVG+AP +E +V IE+ L+ ++ GED Sbjct: 137 SVDLVDIYMRQLKEGVPLSNDTSFGVGYAPFDEVENVVYHIEKKLNSKELKKIHPELGED 196 Query: 201 IKIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEYARERATEHGFGDCEVAINA 260 IK+M VR GE +K+TIACA + R++ D++ Y++++ + + A + AT+ + ++ +N Sbjct: 197 IKVMGVRIGETIKVTIACAFVDRYIKDINDYVEKRENVRKIAYDVATKFTNREVQIYVNT 256 Query: 261 ADDAASDSVYLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAAAGKNPVSHVGKIY 320 DD + +VY+TVTGTSAEAGDDG+VGRGNRVNGLITP+RPMSLEAAAGKNP++HVGK+Y Sbjct: 257 GDDIENQNVYITVTGTSAEAGDDGEVGRGNRVNGLITPYRPMSLEAAAGKNPITHVGKLY 316 Query: 321 NVLAKRVAETLVEAIPQVSAAQCLVVSRIGAPVSIPDLIHLRLATKDGVPPEELRERGAE 380 N+ A +A+ ++E IP++ A C +VS+IG PV+ P + +++ T + PE + R Sbjct: 317 NITANEIAKAVIENIPEIEEAYCYMVSQIGKPVNEPLAVDVKIRTSEK--PESFQSRIDT 374 Query: 381 IVSDHLGRIPELVGELVAGEIQLY 404 IV D L + +LV EI +Y Sbjct: 375 IVKDCLSEMKNTWKKLVEEEITVY 398 >ref|ZP_05099693.1| S-adenosylmethionine synthetase [Roseobacter sp. GAI101] gb|EEB83995.1| S-adenosylmethionine synthetase [Roseobacter sp. GAI101] Length = 405 Score = 371 bits (952), Expect = e-100, Method: Compositional matrix adjust. Identities = 191/394 (48%), Positives = 254/394 (64%), Gaps = 4/394 (1%) Query: 12 VVSRLDITE----EVEVAERKGAGHPDTICDALAETLSRNLCREYVSRFGRVLHHNVDKA 67 VS LD E +VE+ ERKG GHPD+ICDA+AE S +LCR Y+ RFG VLHHNVDKA Sbjct: 4 TVSTLDTPEMETLDVEIVERKGLGHPDSICDAIAEHFSLSLCRFYLDRFGLVLHHNVDKA 63 Query: 68 LLCGGRAMPAFGGGKVTNPIRIFLAGRAATNVGNERIPVEDITIEGSRAWLKANLHALDA 127 LL GG A PAFGGG+V P F+AGRA ++PVE + + + AWL+ ++HALD Sbjct: 64 LLWGGSARPAFGGGQVNQPFEFFVAGRATAAFKGIKVPVEALFHDAATAWLRQHMHALDP 123 Query: 128 DRHVRVEALVRQGSQDLQSLFSRGSTQRNPLANDTSFGVGHAPLSALERLVLAIEQGLHG 187 + L R GS DL LF R ++ LANDTS G+G+APLS LE +VL +E+ L+ Sbjct: 124 TTNAVFHTLTRSGSPDLVELFLRQRSEGVALANDTSLGIGYAPLSELETVVLRVEEHLNS 183 Query: 188 RDRAHDRLAWGEDIKIMAVRSGEGVKLTIACAMIGRFLNDMDSYLQQKAALAEYARERAT 247 GEDIKIM VR + LTI+CA + RF+ M Y KA +AE A++ + Sbjct: 184 PPVKAAHPEIGEDIKIMGVRKAGTMYLTISCAFVDRFVAGMHDYCAAKARVAEIAKKIGS 243 Query: 248 EHGFGDCEVAINAADDAASDSVYLTVTGTSAEAGDDGQVGRGNRVNGLITPWRPMSLEAA 307 V +NAADD A+ SV+LTVTGTSAEAGDDG+ GRGNR NGLITP+RPM++E+ Sbjct: 244 RLTDRQMVVTVNAADDIAAGSVFLTVTGTSAEAGDDGEAGRGNRANGLITPYRPMTMESI 303 Query: 308 AGKNPVSHVGKIYNVLAKRVAETLVEAIPQVSAAQCLVVSRIGAPVSIPDLIHLRLATKD 367 AGKNP++HVGK+YN+LA +A LV IP V+ AQC +VS IG P+ P + +++ +D Sbjct: 304 AGKNPITHVGKLYNLLAGLMAHALVREIPDVTEAQCFLVSEIGRPIDEPQTVDIKVRLRD 363 Query: 368 GVPPEELRERGAEIVSDHLGRIPELVGELVAGEI 401 + R EI +D + R+ ++ + ++GEI Sbjct: 364 PCLLPDTRRHAQEIAADQISRLGQIWSQSLSGEI 397