BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0051.0040.p (458 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001203518.1| aldehyde dehydrogenase [Bradyrhizobium sp. O... 809 0.0 ref|YP_001242517.1| aldehyde dehydrogenase [Bradyrhizobium sp. B... 804 0.0 gb|AAC13641.1| chloroacetaldehyde dehydrogenase [Xanthobacter au... 802 0.0 ref|ZP_08072169.1| Aldehyde Dehydrogenase [Methylocystis sp. ATC... 798 0.0 ref|YP_003694329.1| aldehyde dehydrogenase (NAD(+)) [Starkeya no... 794 0.0 >ref|YP_001203518.1| aldehyde dehydrogenase [Bradyrhizobium sp. ORS 278] emb|CAL75281.1| aldehyde dehydrogenase [Bradyrhizobium sp. ORS 278] Length = 514 Score = 809 bits (2089), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/505 (77%), Positives = 422/505 (83%), Gaps = 47/505 (9%) Query: 1 MNKVDMQSVLKAPFAKRYGNX--------HSGKYFDNVSPVTGLPICEIPRSDAADIE-- 50 M KVD+ + + PFA RY N +GKYFDN+SP+TG P+C+I RSDA+DIE Sbjct: 10 MTKVDVNAAFQPPFAARYDNFIGGAWKAPSAGKYFDNISPITGQPVCQIARSDASDIEAA 69 Query: 51 -------------------------------------AALDAAHXGKPIRETMAADIPLA 73 A + GKPIRET AADIPLA Sbjct: 70 LDAAHAAKDGWARTSVTERALILNRIADRMEANLAKLALAETWDNGKPIRETTAADIPLA 129 Query: 74 IDHFRYFASAIRGQEGSISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAA 133 IDHFRYFA IRGQEGSI+EIDHDT+AYHFHEPLGVVGQIIPWNFPILMA WKLAPALAA Sbjct: 130 IDHFRYFAGVIRGQEGSIAEIDHDTIAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAA 189 Query: 134 GNCVVIKPAEQTPASIMTWLELVGDLLPKGVLNVVNGFGLEAGKPLASSNRIAKIAFTGE 193 GNCVV+KPAEQTPASIM W+E++GDLLP GVLNVVNGFGLEAGKPLASS RIAKIAFTGE Sbjct: 190 GNCVVMKPAEQTPASIMVWMEIIGDLLPAGVLNVVNGFGLEAGKPLASSPRIAKIAFTGE 249 Query: 194 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC 253 T+TGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDF DKAIEGFVMFALNQGEVC Sbjct: 250 TSTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFLDKAIEGFVMFALNQGEVC 309 Query: 254 TCPSRALIHESIYDRFMERALKRVAAITQGSPLDPTTMIGAQASSEQLEKILSYIDIGKK 313 TCPSRALIHESIY+RFMERALKRV AI QGSPLDP TMIGAQASSEQL+KILSYI IG+ Sbjct: 310 TCPSRALIHESIYERFMERALKRVGAIVQGSPLDPATMIGAQASSEQLDKILSYIAIGRN 369 Query: 314 EGAKVLAGGERNNLGGGLSGGYYVKPTVFEGNNKMRVFQEEIFGPVVSVTTFKTDEEALS 373 EGA++L GGERN LGG L+GGYYVKPTVF+G+NKMRVFQEEIFGPVVSVTTFKT++EALS Sbjct: 370 EGAQLLIGGERNLLGGELAGGYYVKPTVFKGHNKMRVFQEEIFGPVVSVTTFKTEDEALS 429 Query: 374 IANDTLYGLGAGVWSRDANRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 433 IANDTLYGLGAGVWSRDAN CYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSG+GRE H Sbjct: 430 IANDTLYGLGAGVWSRDANTCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGVGRETH 489 Query: 434 KMMLDHYQQTKNMLVSYSAKKLGFF 458 K+MLDHYQQTKNMLVSYS KKLGFF Sbjct: 490 KVMLDHYQQTKNMLVSYSPKKLGFF 514 >ref|YP_001242517.1| aldehyde dehydrogenase [Bradyrhizobium sp. BTAi1] gb|ABQ38611.1| aldehyde dehydrogenase [Bradyrhizobium sp. BTAi1] Length = 514 Score = 804 bits (2077), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/505 (77%), Positives = 422/505 (83%), Gaps = 47/505 (9%) Query: 1 MNKVDMQSVLKAPFAKRYGNX--------HSGKYFDNVSPVTGLPICEIPRSDAADIE-- 50 M KVD+ + LK PFA RY N ++GKYFDN+SP+TG P+C+I RSDA+DIE Sbjct: 10 MTKVDVHAALKPPFAARYDNFIGGAWKAPNAGKYFDNISPITGQPVCQIARSDASDIEAA 69 Query: 51 -------------------------------------AALDAAHXGKPIRETMAADIPLA 73 A + GKPIRET AADIPLA Sbjct: 70 LDAAHAAKDGWARTSVTERAQILNKIADRMEANLAKLALAETWDNGKPIRETTAADIPLA 129 Query: 74 IDHFRYFASAIRGQEGSISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAA 133 IDHFRYFA IR QEGSI+EIDHDT+AYHFHEPLGVVGQIIPWNFPILMA WKLAPALAA Sbjct: 130 IDHFRYFAGVIRAQEGSIAEIDHDTIAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAA 189 Query: 134 GNCVVIKPAEQTPASIMTWLELVGDLLPKGVLNVVNGFGLEAGKPLASSNRIAKIAFTGE 193 GNCVV+KPAEQTPASI+ ++L+GDLLP GVLNVVNGFGLEAGKPLASSNRIAKIAFTGE Sbjct: 190 GNCVVLKPAEQTPASILVLMDLIGDLLPAGVLNVVNGFGLEAGKPLASSNRIAKIAFTGE 249 Query: 194 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC 253 T+TGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC Sbjct: 250 TSTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC 309 Query: 254 TCPSRALIHESIYDRFMERALKRVAAITQGSPLDPTTMIGAQASSEQLEKILSYIDIGKK 313 TCPSRALIHESIY+RFMERAL+RV AI QGSPLDP TMIGAQAS+EQL KILSYI+IG+ Sbjct: 310 TCPSRALIHESIYERFMERALQRVGAIVQGSPLDPATMIGAQASAEQLSKILSYIEIGRN 369 Query: 314 EGAKVLAGGERNNLGGGLSGGYYVKPTVFEGNNKMRVFQEEIFGPVVSVTTFKTDEEALS 373 EGA++L GGERN LGG L+GGYYVKPTVF G+NKMRVFQEEIFGPVVSVTTFKT++EAL+ Sbjct: 370 EGAQLLIGGERNVLGGDLAGGYYVKPTVFRGHNKMRVFQEEIFGPVVSVTTFKTEDEALA 429 Query: 374 IANDTLYGLGAGVWSRDANRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 433 IANDTLYGLGAGVWSRDAN CYRFGR IQAGRVWTNCYHAYPAHAAFGGYKQSG+GRE H Sbjct: 430 IANDTLYGLGAGVWSRDANTCYRFGRNIQAGRVWTNCYHAYPAHAAFGGYKQSGVGRETH 489 Query: 434 KMMLDHYQQTKNMLVSYSAKKLGFF 458 K+MLDHYQQTKNMLVSYS KKLGFF Sbjct: 490 KVMLDHYQQTKNMLVSYSPKKLGFF 514 >gb|AAC13641.1| chloroacetaldehyde dehydrogenase [Xanthobacter autotrophicus] Length = 505 Score = 802 bits (2071), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/505 (78%), Positives = 415/505 (82%), Gaps = 47/505 (9%) Query: 1 MNKVDMQSVLKAPFAKRYGNXHSGK--------YFDNVSPVTGLPICEIPRSDAADIEAA 52 MNK ++ ++PF RYGN GK YFDN SPVTG ICEI RSDA DIE A Sbjct: 1 MNKPEIAITKQSPFKARYGNFIGGKFVEPVGGRYFDNTSPVTGGKICEIARSDADDIEKA 60 Query: 53 LDAAHX---------------------------------------GKPIRETMAADIPLA 73 LDAAH GKPIRET AAD+PLA Sbjct: 61 LDAAHAAKDAWGKTSAAVRALILNRIADRMEENLDLLALAETWDNGKPIRETTAADMPLA 120 Query: 74 IDHFRYFASAIRGQEGSISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAA 133 IDHFRYFA A+R QEG ISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMA WKLAPALAA Sbjct: 121 IDHFRYFAGAVRAQEGGISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAA 180 Query: 134 GNCVVIKPAEQTPASIMTWLELVGDLLPKGVLNVVNGFGLEAGKPLASSNRIAKIAFTGE 193 GNCVV+KPAEQTPASI+ EL+ DLLP GVLN+VNGFGLEAGKPLASS+RIAKIAFTGE Sbjct: 181 GNCVVLKPAEQTPASILVLAELIADLLPPGVLNIVNGFGLEAGKPLASSSRIAKIAFTGE 240 Query: 194 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC 253 TTTGRLIMQYASQNLIPVTLELGGKSPNIFF DV AEDDDFFDKA+EGFVMFALNQGEVC Sbjct: 241 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFADVVAEDDDFFDKAVEGFVMFALNQGEVC 300 Query: 254 TCPSRALIHESIYDRFMERALKRVAAITQGSPLDPTTMIGAQASSEQLEKILSYIDIGKK 313 TCPSRALI ESIYDRFME+ALKRVAAI QGSPLDP TMIGAQASSEQLEKILSYIDIGK+ Sbjct: 301 TCPSRALIQESIYDRFMEKALKRVAAIVQGSPLDPATMIGAQASSEQLEKILSYIDIGKQ 360 Query: 314 EGAKVLAGGERNNLGGGLSGGYYVKPTVFEGNNKMRVFQEEIFGPVVSVTTFKTDEEALS 373 EGA+VL GGERN GG L+GGYYVKPTVF+G+NKMR+FQEEIFGPVVSVTTF D EAL Sbjct: 361 EGAEVLIGGERNTFGGDLAGGYYVKPTVFKGHNKMRIFQEEIFGPVVSVTTFTDDAEALH 420 Query: 374 IANDTLYGLGAGVWSRDANRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 433 IANDTLYGLGAGVW+RD NR YRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH Sbjct: 421 IANDTLYGLGAGVWTRDGNRAYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 480 Query: 434 KMMLDHYQQTKNMLVSYSAKKLGFF 458 KMMLDHYQQTKNMLVSYS KKLGFF Sbjct: 481 KMMLDHYQQTKNMLVSYSPKKLGFF 505 >ref|ZP_08072169.1| Aldehyde Dehydrogenase [Methylocystis sp. ATCC 49242] gb|EFY00372.1| Aldehyde Dehydrogenase [Methylocystis sp. ATCC 49242] Length = 505 Score = 798 bits (2060), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/505 (77%), Positives = 412/505 (81%), Gaps = 47/505 (9%) Query: 1 MNKVDMQSVLKAPFAKRYGN--------XHSGKYFDNVSPVTGLPICEIPRSDAADIE-- 50 M K + + LK PF RYGN SG+ FDN+SP+TG +CEI RSD DIE Sbjct: 1 MTKHETFAALKPPFKARYGNFINGEWRDAKSGRVFDNISPITGQKVCEIARSDKDDIEAA 60 Query: 51 -------------------------------------AALDAAHXGKPIRETMAADIPLA 73 A + GKPIRETMAADIPLA Sbjct: 61 LDAAHAARDAWGKASTTERARILNRIADRMEENLAVLATAETWDNGKPIRETMAADIPLA 120 Query: 74 IDHFRYFASAIRGQEGSISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAA 133 IDHFRYFA A+R QEG ISEIDHDTVAYHFHEPLGVVGQIIPWNFP+LMA WKLAPALAA Sbjct: 121 IDHFRYFAGAVRAQEGGISEIDHDTVAYHFHEPLGVVGQIIPWNFPLLMAAWKLAPALAA 180 Query: 134 GNCVVIKPAEQTPASIMTWLELVGDLLPKGVLNVVNGFGLEAGKPLASSNRIAKIAFTGE 193 GNCVVIKPAEQTPASI+ W E+VGDLLPKGVLN+VNGFGLEAGKPLASSNRIAKIAFTGE Sbjct: 181 GNCVVIKPAEQTPASILVWAEIVGDLLPKGVLNIVNGFGLEAGKPLASSNRIAKIAFTGE 240 Query: 194 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC 253 TTTGRLIMQYASQ LIPVTLELGGKSPNIFF+DV EDDD+ DKA+EGFVMFALNQGEVC Sbjct: 241 TTTGRLIMQYASQTLIPVTLELGGKSPNIFFEDVAREDDDYLDKAVEGFVMFALNQGEVC 300 Query: 254 TCPSRALIHESIYDRFMERALKRVAAITQGSPLDPTTMIGAQASSEQLEKILSYIDIGKK 313 TCPSRAL+HE IYDRFMERALKRV I QG+PLDP TMIGAQASSEQLEKILSYIDIGK+ Sbjct: 301 TCPSRALVHEKIYDRFMERALKRVGDIKQGNPLDPETMIGAQASSEQLEKILSYIDIGKQ 360 Query: 314 EGAKVLAGGERNNLGGGLSGGYYVKPTVFEGNNKMRVFQEEIFGPVVSVTTFKTDEEALS 373 EGAKVLAGGERN L G L+GGYYVKPTV G+N+MRVFQEEIFGPVVSVTTFK D+EAL Sbjct: 361 EGAKVLAGGERNTLEGDLAGGYYVKPTVLHGHNRMRVFQEEIFGPVVSVTTFKDDDEALH 420 Query: 374 IANDTLYGLGAGVWSRDANRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 433 IANDTLYGLGAGVWSRD NRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH Sbjct: 421 IANDTLYGLGAGVWSRDINRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 480 Query: 434 KMMLDHYQQTKNMLVSYSAKKLGFF 458 KMMLDHYQQTKNMLVSYS KKLGFF Sbjct: 481 KMMLDHYQQTKNMLVSYSPKKLGFF 505 >ref|YP_003694329.1| aldehyde dehydrogenase (NAD(+)) [Starkeya novella DSM 506] gb|ADH89710.1| Aldehyde dehydrogenase (NAD(+)) [Starkeya novella DSM 506] Length = 505 Score = 794 bits (2051), Expect = 0.0, Method: Compositional matrix adjust. Identities = 384/505 (76%), Positives = 418/505 (82%), Gaps = 47/505 (9%) Query: 1 MNKVDMQSVLKAPFAKRYGNX--------HSGKYFDNVSPVTGLPICEIPRSDAADIEAA 52 MNK ++ ++PF RYGN +G+YFDN SP+TG ICE+ RSD DIE A Sbjct: 1 MNKPELSITKQSPFKARYGNFIGGQFVEPVNGRYFDNTSPITGGKICEVARSDKDDIEKA 60 Query: 53 LDAAHX---------------------------------------GKPIRETMAADIPLA 73 LDAAH GKPIRET AADIPLA Sbjct: 61 LDAAHAAKDAWGKTSAAERALILNKVADRMEENLDLLALAETWDNGKPIRETTAADIPLA 120 Query: 74 IDHFRYFASAIRGQEGSISEIDHDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAA 133 IDHFRYFA+ +R QEG++SEIDHDT+AYHFHEPLGVVGQIIPWNFPILMA WKLAPALAA Sbjct: 121 IDHFRYFAACVRAQEGNLSEIDHDTIAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAA 180 Query: 134 GNCVVIKPAEQTPASIMTWLELVGDLLPKGVLNVVNGFGLEAGKPLASSNRIAKIAFTGE 193 GNCVV+KPAEQTP+S++ ELV DLLP GVLN+VNG+GLEAGKPLAS+ RIAKIAFTGE Sbjct: 181 GNCVVLKPAEQTPSSVLVLAELVADLLPPGVLNIVNGYGLEAGKPLASNPRIAKIAFTGE 240 Query: 194 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVCAEDDDFFDKAIEGFVMFALNQGEVC 253 TTTGRLIMQYASQNLIPVTLELGGKSPNIFF DV AEDDDFFDKA+EGFVMFALNQGEVC Sbjct: 241 TTTGRLIMQYASQNLIPVTLELGGKSPNIFFGDVVAEDDDFFDKAVEGFVMFALNQGEVC 300 Query: 254 TCPSRALIHESIYDRFMERALKRVAAITQGSPLDPTTMIGAQASSEQLEKILSYIDIGKK 313 TCPSRALI ES+YDRFME+ALKRV I QGSPLDP+TMIGAQASSEQL+KILSYIDIGK+ Sbjct: 301 TCPSRALIQESVYDRFMEKALKRVEDIVQGSPLDPSTMIGAQASSEQLDKILSYIDIGKQ 360 Query: 314 EGAKVLAGGERNNLGGGLSGGYYVKPTVFEGNNKMRVFQEEIFGPVVSVTTFKTDEEALS 373 EGA+VL GGERNNLGG L+GGYYVKPTVF+G+N+MR+FQEEIFGPVVSVTTFK DEEALS Sbjct: 361 EGAQVLTGGERNNLGGDLAGGYYVKPTVFKGHNRMRIFQEEIFGPVVSVTTFKDDEEALS 420 Query: 374 IANDTLYGLGAGVWSRDANRCYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENH 433 IANDTLYGLGAGVW+RD NR YRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRE H Sbjct: 421 IANDTLYGLGAGVWTRDGNRAYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETH 480 Query: 434 KMMLDHYQQTKNMLVSYSAKKLGFF 458 KMMLDHYQQTKN+LVSYS KKLGFF Sbjct: 481 KMMLDHYQQTKNLLVSYSPKKLGFF 505