BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0038.p (462 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_767056.1| isopropylmalate isomerase large subunit [Bradyr... 771 0.0 sp|Q89X98.2|LEUC1_BRAJA RecName: Full=3-isopropylmalate dehydrat... 770 0.0 ref|YP_001682139.1| isopropylmalate isomerase large subunit [Cau... 577 e-162 ref|YP_004619281.1| alpha-IPM isomerase [Ramlibacter tataouinens... 563 e-158 ref|YP_004128105.1| 3-isopropylmalate dehydratase, large subunit... 551 e-154 >ref|NP_767056.1| isopropylmalate isomerase large subunit [Bradyrhizobium japonicum USDA 110] dbj|BAC45681.1| 3-isopropylmalate dehydratase large subunit [Bradyrhizobium japonicum USDA 110] Length = 512 Score = 771 bits (1992), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/462 (83%), Positives = 419/462 (90%) Query: 1 LLEKIWDQHVIARLSEDTDLLHIDRHLLHDLGGSRGLLDLKSRGLKVHNPELTFATPDHA 60 LL KIWDQHVIA +S+DTDLLH+DRHLLHDLGGSRGL+DLKSR L VHNPELTFATPDHA Sbjct: 51 LLAKIWDQHVIAHVSDDTDLLHVDRHLLHDLGGSRGLIDLKSRNLPVHNPELTFATPDHA 110 Query: 61 LSTAPGRAGTSKIGLELLAALRVETSASGITLFDVDQPGQGIVHVIGPELGLSLPGATIV 120 +STA GRAGT G ELLAALR ETSASGI LFD+DQPGQGIVHVIGPELGLSLPG IV Sbjct: 111 ISTASGRAGTITTGQELLAALRTETSASGIRLFDIDQPGQGIVHVIGPELGLSLPGCLIV 170 Query: 121 CGDSHTCTHGGLGALAFGIGSSELTHVLATQALIQRRPKTMRARFEGKLPLGVTAKDMIL 180 CGDSHTCTHGGLGALAFGIGSSELTHVLATQ +IQRRPKTMR F+G++P GVTAKD+IL Sbjct: 171 CGDSHTCTHGGLGALAFGIGSSELTHVLATQTIIQRRPKTMRVTFDGRMPFGVTAKDLIL 230 Query: 181 ALIGHIGAAGGTGYAVEYAGSAIRALPIEGRLTICNLSIELGAKMGMVAPDEKTFEFLRG 240 ALIGH+GAAGGTGYAVEYAGSAIR +PIEGRLTICNLS+ELGAKMG++APD+ TF+++RG Sbjct: 231 ALIGHVGAAGGTGYAVEYAGSAIRGMPIEGRLTICNLSVELGAKMGLIAPDQTTFDYVRG 290 Query: 241 RPYAPQGEMWDLAVKAWRELPSDPDAVFDREVVIDVEKIIPQVTWGISPEHVVGVDGMIP 300 RPYAPQGEMW+ AV AWR L SD DA+FDREV IDV IIPQ+TWG SPEHV+GVDG +P Sbjct: 291 RPYAPQGEMWERAVTAWRTLRSDSDAMFDREVTIDVGTIIPQITWGTSPEHVLGVDGRVP 350 Query: 301 DPKAVDDPLRRAAIETALEYMGLQGGAPIAGTPVDWVFIGSCTNSRLSDLRAAAEVARGR 360 DP+ + DP RR AIE AL+YMGL+ GAPIAGT VDWVFIGSCTNSRLSDLRAAAEVARGR Sbjct: 351 DPRDIADPARRGAIEIALDYMGLKPGAPIAGTKVDWVFIGSCTNSRLSDLRAAAEVARGR 410 Query: 361 KVAAGVRAWVVPGSENVKREAVAEGLDKIFIDAGFEWREPGCSMCLAANGEVVAPGQRSV 420 KVA GVRAWVVPGSE VKR+AVAEGLDKIFIDAGFEWREPGCSMCLAANGE V PGQRSV Sbjct: 411 KVAPGVRAWVVPGSETVKRDAVAEGLDKIFIDAGFEWREPGCSMCLAANGETVPPGQRSV 470 Query: 421 STSNRNFVGRQGPRARTHLASPASAAASAIAGAIADVRMMGR 462 STSNRNF+GRQGPRARTHLASPA AAA+A++GAIADVR M R Sbjct: 471 STSNRNFIGRQGPRARTHLASPAMAAAAAVSGAIADVRTMER 512 >sp|Q89X98.2|LEUC1_BRAJA RecName: Full=3-isopropylmalate dehydratase large subunit 1; AltName: Full=Alpha-IPM isomerase 1; Short=IPMI 1; AltName: Full=Isopropylmalate isomerase 1 Length = 477 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/462 (83%), Positives = 419/462 (90%) Query: 1 LLEKIWDQHVIARLSEDTDLLHIDRHLLHDLGGSRGLLDLKSRGLKVHNPELTFATPDHA 60 LL KIWDQHVIA +S+DTDLLH+DRHLLHDLGGSRGL+DLKSR L VHNPELTFATPDHA Sbjct: 16 LLAKIWDQHVIAHVSDDTDLLHVDRHLLHDLGGSRGLIDLKSRNLPVHNPELTFATPDHA 75 Query: 61 LSTAPGRAGTSKIGLELLAALRVETSASGITLFDVDQPGQGIVHVIGPELGLSLPGATIV 120 +STA GRAGT G ELLAALR ETSASGI LFD+DQPGQGIVHVIGPELGLSLPG IV Sbjct: 76 ISTASGRAGTITTGQELLAALRTETSASGIRLFDIDQPGQGIVHVIGPELGLSLPGCLIV 135 Query: 121 CGDSHTCTHGGLGALAFGIGSSELTHVLATQALIQRRPKTMRARFEGKLPLGVTAKDMIL 180 CGDSHTCTHGGLGALAFGIGSSELTHVLATQ +IQRRPKTMR F+G++P GVTAKD+IL Sbjct: 136 CGDSHTCTHGGLGALAFGIGSSELTHVLATQTIIQRRPKTMRVTFDGRMPFGVTAKDLIL 195 Query: 181 ALIGHIGAAGGTGYAVEYAGSAIRALPIEGRLTICNLSIELGAKMGMVAPDEKTFEFLRG 240 ALIGH+GAAGGTGYAVEYAGSAIR +PIEGRLTICNLS+ELGAKMG++APD+ TF+++RG Sbjct: 196 ALIGHVGAAGGTGYAVEYAGSAIRGMPIEGRLTICNLSVELGAKMGLIAPDQTTFDYVRG 255 Query: 241 RPYAPQGEMWDLAVKAWRELPSDPDAVFDREVVIDVEKIIPQVTWGISPEHVVGVDGMIP 300 RPYAPQGEMW+ AV AWR L SD DA+FDREV IDV IIPQ+TWG SPEHV+GVDG +P Sbjct: 256 RPYAPQGEMWERAVTAWRTLRSDSDAMFDREVTIDVGTIIPQITWGTSPEHVLGVDGRVP 315 Query: 301 DPKAVDDPLRRAAIETALEYMGLQGGAPIAGTPVDWVFIGSCTNSRLSDLRAAAEVARGR 360 DP+ + DP RR AIE AL+YMGL+ GAPIAGT VDWVFIGSCTNSRLSDLRAAAEVARGR Sbjct: 316 DPRDIADPARRGAIEIALDYMGLKPGAPIAGTKVDWVFIGSCTNSRLSDLRAAAEVARGR 375 Query: 361 KVAAGVRAWVVPGSENVKREAVAEGLDKIFIDAGFEWREPGCSMCLAANGEVVAPGQRSV 420 KVA GVRAWVVPGSE VKR+AVAEGLDKIFIDAGFEWREPGCSMCLAANGE V PGQRSV Sbjct: 376 KVAPGVRAWVVPGSETVKRDAVAEGLDKIFIDAGFEWREPGCSMCLAANGETVPPGQRSV 435 Query: 421 STSNRNFVGRQGPRARTHLASPASAAASAIAGAIADVRMMGR 462 STSNRNF+GRQGPRARTHLASPA AAA+A++GAIADVR M R Sbjct: 436 STSNRNFIGRQGPRARTHLASPAMAAAAAVSGAIADVRTMER 477 >ref|YP_001682139.1| isopropylmalate isomerase large subunit [Caulobacter sp. K31] gb|ABZ69641.1| 3-isopropylmalate dehydratase, large subunit [Caulobacter sp. K31] Length = 481 Score = 577 bits (1487), Expect = e-162, Method: Compositional matrix adjust. Identities = 285/461 (61%), Positives = 344/461 (74%), Gaps = 1/461 (0%) Query: 1 LLEKIWDQHVIARLSEDTDLLHIDRHLLHDLGGSRGLLDLKSRGLKVHNPELTFATPDHA 60 + +K+WD HV+ L LLHIDRH++HDL G L L++RGL V N ELTFATPDHA Sbjct: 21 MQDKLWDAHVVRDLGGGWSLLHIDRHIIHDLSGPVALAQLEARGLPVRNRELTFATPDHA 80 Query: 61 LSTAPGRAG-TSKIGLELLAALRVETSASGITLFDVDQPGQGIVHVIGPELGLSLPGATI 119 +S+ PGR G T G L A L+ + GI FD GQGIVHV+GPELGL+LPG T+ Sbjct: 81 VSSLPGRTGATYPPGERLWAKLKAGSEREGIRFFDTGTEGQGIVHVMGPELGLALPGMTL 140 Query: 120 VCGDSHTCTHGGLGALAFGIGSSELTHVLATQALIQRRPKTMRARFEGKLPLGVTAKDMI 179 +CGDSHTCT+GG+GALAFG+G SE H LATQ L RRP TMR +G L LGVTAKD+ Sbjct: 141 ICGDSHTCTNGGIGALAFGVGQSESMHALATQCLRLRRPLTMRINIDGVLGLGVTAKDVA 200 Query: 180 LALIGHIGAAGGTGYAVEYAGSAIRALPIEGRLTICNLSIELGAKMGMVAPDEKTFEFLR 239 L L+ +G +GG + +EYAGS +RA+ +E RLT+CNL++ELGA+ G VA D+ TF ++ Sbjct: 201 LHLLRRLGTSGGLEHTIEYAGSTVRAMGVEARLTLCNLTVELGARSGFVAADDTTFAYVD 260 Query: 240 GRPYAPQGEMWDLAVKAWRELPSDPDAVFDREVVIDVEKIIPQVTWGISPEHVVGVDGMI 299 GRP+AP+G +D AV WR SD +A FDRE+ ID I P +TWG++PE V+ VDG + Sbjct: 261 GRPFAPKGAAFDRAVALWRGFASDDEARFDREISIDAADIAPTLTWGVTPEQVISVDGRV 320 Query: 300 PDPKAVDDPLRRAAIETALEYMGLQGGAPIAGTPVDWVFIGSCTNSRLSDLRAAAEVARG 359 PDP AV D +R A+ AL+YMGL G + VDWVFIGSC NSRLSDLRAAA++A+G Sbjct: 321 PDPSAVSDETQREAMVQALDYMGLTPGQALTDAVVDWVFIGSCANSRLSDLRAAAQIAKG 380 Query: 360 RKVAAGVRAWVVPGSENVKREAVAEGLDKIFIDAGFEWREPGCSMCLAANGEVVAPGQRS 419 R+VAAGV AWVVPGSE VKR A AEGLDKIF+DAGF WREPGCSMC+AANGE V PG R+ Sbjct: 381 RRVAAGVTAWVVPGSEIVKRAAEAEGLDKIFLDAGFAWREPGCSMCVAANGETVPPGARA 440 Query: 420 VSTSNRNFVGRQGPRARTHLASPASAAASAIAGAIADVRMM 460 VSTSNRNFVGRQGPRARTHLASPA+A ASAI G IADVR + Sbjct: 441 VSTSNRNFVGRQGPRARTHLASPATAVASAIRGKIADVRAL 481 >ref|YP_004619281.1| alpha-IPM isomerase [Ramlibacter tataouinensis TTB310] gb|AEG93262.1| Alpha-IPM isomerase [Ramlibacter tataouinensis TTB310] Length = 465 Score = 563 bits (1450), Expect = e-158, Method: Compositional matrix adjust. Identities = 292/461 (63%), Positives = 357/461 (77%), Gaps = 3/461 (0%) Query: 1 LLEKIWDQHVIARLSEDTDLLHIDRHLLHDLGGSRGLLDLKSRGLKVHNPELTFATPDHA 60 L +K+WD HV+ L + LLHIDRHL+HDLGG G ++ +RGL++H+P LTFATPDHA Sbjct: 6 LFDKLWDAHVVRDLGDGWALLHIDRHLMHDLGGGPGFAEIAARGLELHDPGLTFATPDHA 65 Query: 61 LSTAPGRAGTS-KIGLELLAALRVETSASGITLFDVDQPGQGIVHVIGPELGLSLPGATI 119 +S+ PGR T+ +G L AALR ++G+ FD+ PGQGIVHV+ PELG+ LPG ++ Sbjct: 66 VSSQPGRVATTFPLGGRLHAALRDGAKSAGVQFFDLGAPGQGIVHVMAPELGIVLPGLSV 125 Query: 120 VCGDSHTCTHGGLGALAFGIGSSELTHVLATQALIQRRPKTMRARFEGKLPLGVTAKDMI 179 VC DSHTCT+GG+GALAFGIGSSE HVLATQ L Q++P+ MR R EG L GVTAKD+ Sbjct: 126 VCTDSHTCTNGGIGALAFGIGSSESVHVLATQTLRQQKPRRMRIRCEGTLASGVTAKDLA 185 Query: 180 LALIGHIGAAGGTGYAVEYAGSAIRALPIEGRLTICNLSIELGAKMGMVAPDEKTFEFLR 239 L +IG +GAA G G+AVE+AG AI AL +E RLT+CNL++ELGA+ G+VAPDE+T ++ Sbjct: 186 LHIIGRLGAAAGVGHAVEFAGPAIEALEVEARLTLCNLAVELGARFGLVAPDERTIAWVA 245 Query: 240 GRPYAPQGEMWDLAVKAWRELPSDPDAVFDREVVIDVEKIIPQVTWGISPEHVVGVDGMI 299 GRP+AP+G ++ A WR+L +DPDAVFD E ID ++ P VTWG SPEH + +D + Sbjct: 246 GRPWAPEGAAFEAAAAYWRKLTTDPDAVFDSEETIDASQVAPTVTWGTSPEHAIAIDAAV 305 Query: 300 PDPKAVDDPLRRAAIETALEYMGLQGGAPIAGTPVDWVFIGSCTNSRLSDLRAAAEVARG 359 PDP + + A AL YMGLQ APIAGTPVDWVFIGSC NSRLSDLRAAA++ARG Sbjct: 306 PDPATLGPRAQEGA--AALAYMGLQPNAPIAGTPVDWVFIGSCANSRLSDLRAAAQIARG 363 Query: 360 RKVAAGVRAWVVPGSENVKREAVAEGLDKIFIDAGFEWREPGCSMCLAANGEVVAPGQRS 419 RKVA+GV+AWVVPGSE VKR A AEGL ++F +AGFEWREPGCSMC+AANGE V PGQRS Sbjct: 364 RKVASGVKAWVVPGSEIVKRAAEAEGLHRLFTEAGFEWREPGCSMCVAANGEQVPPGQRS 423 Query: 420 VSTSNRNFVGRQGPRARTHLASPASAAASAIAGAIADVRMM 460 VSTSNRNFVGRQGP ARTHLASPA AAA+AIAG I D R + Sbjct: 424 VSTSNRNFVGRQGPGARTHLASPAVAAAAAIAGCIIDPRAL 464 >ref|YP_004128105.1| 3-isopropylmalate dehydratase, large subunit [Alicycliphilus denitrificans BC] ref|YP_004389778.1| 3-isopropylmalate dehydratase, large subunit [Alicycliphilus denitrificans K601] gb|ADV01218.1| 3-isopropylmalate dehydratase, large subunit [Alicycliphilus denitrificans BC] gb|AEB86262.1| 3-isopropylmalate dehydratase, large subunit [Alicycliphilus denitrificans K601] Length = 469 Score = 551 bits (1419), Expect = e-154, Method: Compositional matrix adjust. Identities = 271/440 (61%), Positives = 332/440 (75%), Gaps = 1/440 (0%) Query: 1 LLEKIWDQHVIARLSEDTDLLHIDRHLLHDLGGSRGLLDLKSRGLKVHNPELTFATPDHA 60 L +K+WD HV+ L++ DLLHIDRHLLHDL G+ GL L RGL V NP L FATPDHA Sbjct: 9 LFDKVWDAHVVQSLADGWDLLHIDRHLLHDLSGTAGLRQLAERGLPVRNPGLAFATPDHA 68 Query: 61 LSTAPGRAG-TSKIGLELLAALRVETSASGITLFDVDQPGQGIVHVIGPELGLSLPGATI 119 +S+AP R G T G L L++ T +GI +FD+ +PGQGIVHV+GPELG+ PG T+ Sbjct: 69 VSSAPDRTGETFAGGARLYQGLKLLTRQAGIRMFDLGEPGQGIVHVMGPELGIVQPGMTL 128 Query: 120 VCGDSHTCTHGGLGALAFGIGSSELTHVLATQALIQRRPKTMRARFEGKLPLGVTAKDMI 179 VCGDSHTCT+G LGA+AFG+GSSE+THVLA+Q L+ RRP+TMR +G GV AKD+ Sbjct: 129 VCGDSHTCTNGALGAIAFGVGSSEVTHVLASQTLVLRRPRTMRVLLDGLPGPGVGAKDLA 188 Query: 180 LALIGHIGAAGGTGYAVEYAGSAIRALPIEGRLTICNLSIELGAKMGMVAPDEKTFEFLR 239 LALIG +GA G G+AVEYAG+A+ A+ +E R+T+CNLSIELGA++GMVAPD KT +LR Sbjct: 189 LALIGWLGANAGNGFAVEYAGAAVEAMEVEQRMTLCNLSIELGARIGMVAPDVKTEAYLR 248 Query: 240 GRPYAPQGEMWDLAVKAWRELPSDPDAVFDREVVIDVEKIIPQVTWGISPEHVVGVDGMI 299 GRP+APQG+ + A+ WR LPSDP A +++E ++ + P +TWG SPEH + VD + Sbjct: 249 GRPFAPQGDAFAQALAHWRTLPSDPGARYEQEWHVNAAAVAPTLTWGTSPEHAMAVDTRV 308 Query: 300 PDPKAVDDPLRRAAIETALEYMGLQGGAPIAGTPVDWVFIGSCTNSRLSDLRAAAEVARG 359 PDP P +R A + AL YMGL+ GAP+ GT +D VFIGSCTNSRLSDLR AA + RG Sbjct: 309 PDPADAASPAQRQAWQAALAYMGLKAGAPLQGTRIDRVFIGSCTNSRLSDLREAAGLLRG 368 Query: 360 RKVAAGVRAWVVPGSENVKREAVAEGLDKIFIDAGFEWREPGCSMCLAANGEVVAPGQRS 419 R+VA V+AWVVPGSENVKR A EGL + F AGF WREPGCSMC+AANGE APG+R Sbjct: 369 RRVAPHVQAWVVPGSENVKRAAEREGLHEAFRAAGFAWREPGCSMCVAANGEQAAPGERV 428 Query: 420 VSTSNRNFVGRQGPRARTHL 439 VSTSNRNFVGRQGP ARTHL Sbjct: 429 VSTSNRNFVGRQGPGARTHL 448