BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0089.p (476 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_02927217.1| adenylosuccinate lyase [Verrucomicrobium spin... 772 0.0 ref|YP_003549498.1| adenylosuccinate lyase [Coraliomargarita aka... 637 0.0 ref|YP_001878535.1| adenylosuccinate lyase [Akkermansia muciniph... 619 e-175 ref|ZP_03724706.1| adenylosuccinate lyase [Opitutaceae bacterium... 583 e-164 ref|ZP_07718377.1| adenylosuccinate lyase [Aeromicrobium marinum... 573 e-161 >ref|ZP_02927217.1| adenylosuccinate lyase [Verrucomicrobium spinosum DSM 4136] Length = 475 Score = 772 bits (1993), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/473 (78%), Positives = 416/473 (87%) Query: 4 DHISNVLAERYASPAMRAIWSGEGKVRLERDYWIAVLKAQRDLGIAVPDGVIESYERVKD 63 D I NVLAERYAS +M AIWSGEGKVRLER+ WIAV+KAQRDLGI VPDGVIESYERVKD Sbjct: 3 DAIPNVLAERYASSSMCAIWSGEGKVRLERELWIAVMKAQRDLGILVPDGVIESYERVKD 62 Query: 64 QINLASIMKRERVTRHDVKARIEEFCELAGHEHLHKGMTSRDLTENVEQLQVYRALQLIE 123 Q+NL SIM+RERVTRHDVKARIEEFC+LAGHEH+HKGMTSRDLTENVEQLQV+R+LQ+++ Sbjct: 63 QVNLDSIMQRERVTRHDVKARIEEFCDLAGHEHIHKGMTSRDLTENVEQLQVFRSLQVVQ 122 Query: 124 TKSVAALIRFATRAKQLRDIPFTARTHNVAAQVTTLGKRIAMSGEEMLLAHQSLVNVLQT 183 KSVAAL++ A RAK+ RDIP TARTHNVAAQVTT+GKRIAM GEEML A+ L +VL + Sbjct: 123 RKSVAALVKLAARAKETRDIPLTARTHNVAAQVTTVGKRIAMFGEEMLGAYHQLQSVLGS 182 Query: 184 YPARGLKGAVGTRLDQITLFNGDAGKARALEQRVLVHLGLPKVLDAVGQVYPRSLDFRAV 243 YPARGLKGAVGTRLDQI+LF GDA KARAL+++V+ +LGLP AVGQVYPRSLD R V Sbjct: 183 YPARGLKGAVGTRLDQISLFEGDAVKARALDEKVVAYLGLPLAFGAVGQVYPRSLDLRVV 242 Query: 244 SVLTELASGPGNFAKTIRLMAGHELASEGFAKGQVGSSAMPHKMNSRSCERINGLHVILK 303 S L +LASGP +FA+T+RLMAG ELASEGFAKGQVGSSAMPHKMNSRSCER+NGLHV+LK Sbjct: 243 SSLVDLASGPADFARTLRLMAGQELASEGFAKGQVGSSAMPHKMNSRSCERVNGLHVVLK 302 Query: 304 GYLAMAAGLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLETLLTVLDQMEVFEAVVETE 363 GYL MA+GLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLET LT+L+QMEVFEAVV TE Sbjct: 303 GYLTMASGLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLETFLTILNQMEVFEAVVATE 362 Query: 364 LNRYLPFLLTTTVMMEAVKKGAGREGAHEAIKEHAVAAIGDLRTGKIVQNDLLQRLAADK 423 L RYLPFLLTTTV+MEAVK GAGREGAHEAIKEHAVA DLRTGK+ NDL RLAAD Sbjct: 363 LQRYLPFLLTTTVLMEAVKSGAGREGAHEAIKEHAVAVAKDLRTGKVRANDLFDRLAADA 422 Query: 424 RLGLSEAELQHVLDQGRANSGDAGAQVDFFAEQVEALAKAKPEAARYNPGTIL 476 RLGL+ A+ + V +QGRANSGDAGAQVD FA +V+A+A PE A Y PG IL Sbjct: 423 RLGLTPAQFEVVFEQGRANSGDAGAQVDEFAARVDAVAANCPEGAAYEPGAIL 475 >ref|YP_003549498.1| adenylosuccinate lyase [Coraliomargarita akajimensis DSM 45221] gb|ADE55328.1| adenylosuccinate lyase [Coraliomargarita akajimensis DSM 45221] Length = 491 Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/475 (64%), Positives = 369/475 (77%) Query: 2 SQDHISNVLAERYASPAMRAIWSGEGKVRLERDYWIAVLKAQRDLGIAVPDGVIESYERV 61 + + NVLA RYAS AMRA+WS EG++ +ERDYWIAVL+AQ++LG+ VP I++YERV Sbjct: 17 TMESTPNVLASRYASEAMRAVWSAEGRIAMERDYWIAVLRAQKELGLDVPQEAIDAYERV 76 Query: 62 KDQINLASIMKRERVTRHDVKARIEEFCELAGHEHLHKGMTSRDLTENVEQLQVYRALQL 121 K QI+L SI +RE +TRHDVKARIEEFC+LAG EH+HKG+TSRDLTENVEQLQ+ RAL++ Sbjct: 77 KGQIDLDSINEREAITRHDVKARIEEFCDLAGFEHIHKGLTSRDLTENVEQLQIIRALEI 136 Query: 122 IETKSVAALIRFATRAKQLRDIPFTARTHNVAAQVTTLGKRIAMSGEEMLLAHQSLVNVL 181 + K VAAL++ A RA++ +D TARTHNV AQ TT GKR+AM GE++L A + L ++ Sbjct: 137 VRVKVVAALLKLAERAEEWKDFVITARTHNVPAQPTTFGKRLAMFGEDLLCAARELDRII 196 Query: 182 QTYPARGLKGAVGTRLDQITLFNGDAGKARALEQRVLVHLGLPKVLDAVGQVYPRSLDFR 241 YP RGLKG VGT++D +TLF GD K LE +L HL + LD VGQVYPR LDF Sbjct: 197 DNYPVRGLKGPVGTQMDLLTLFEGDHSKVEQLEDSILDHLNVGAALDTVGQVYPRGLDFE 256 Query: 242 AVSVLTELASGPGNFAKTIRLMAGHELASEGFAKGQVGSSAMPHKMNSRSCERINGLHVI 301 VSV LASGP +FAKT+R+MAGHELASEGFAKGQVGSSAMPHKMNSRSCER+NG I Sbjct: 257 VVSVFVRLASGPSSFAKTLRIMAGHELASEGFAKGQVGSSAMPHKMNSRSCERLNGFAAI 316 Query: 302 LKGYLAMAAGLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLETLLTVLDQMEVFEAVVE 361 LKGYL MAA L+GDQWNEGDVSCSVVRRV LPD+F A+DGL+ET LT+L+QMEV+ AVV+ Sbjct: 317 LKGYLTMAAELSGDQWNEGDVSCSVVRRVFLPDSFYAIDGLIETFLTILNQMEVYPAVVD 376 Query: 362 TELNRYLPFLLTTTVMMEAVKKGAGREGAHEAIKEHAVAAIGDLRTGKIVQNDLLQRLAA 421 E RY PFL TTTV+MEAVK GAGRE AHEAIKEHAV + DLR GKI QNDL+ RLAA Sbjct: 377 QENQRYGPFLATTTVLMEAVKAGAGREEAHEAIKEHAVQTVRDLRAGKITQNDLVDRLAA 436 Query: 422 DKRLGLSEAELQHVLDQGRANSGDAGAQVDFFAEQVEALAKAKPEAARYNPGTIL 476 D RLGL + E+ V+ + +A +G A QV F EQV A++ PEA Y PG IL Sbjct: 437 DSRLGLPKEEVASVVAKAQAMTGMAADQVAHFCEQVRQEAESFPEAQNYQPGAIL 491 >ref|YP_001878535.1| adenylosuccinate lyase [Akkermansia muciniphila ATCC BAA-835] gb|ACD05754.1| adenylosuccinate lyase [Akkermansia muciniphila ATCC BAA-835] Length = 474 Score = 619 bits (1595), Expect = e-175, Method: Compositional matrix adjust. Identities = 305/471 (64%), Positives = 372/471 (78%) Query: 6 ISNVLAERYASPAMRAIWSGEGKVRLERDYWIAVLKAQRDLGIAVPDGVIESYERVKDQI 65 I NVLAERYAS AM++IWS EG++ LER++WIAV+KAQ+DLG+ +PDGVIE+YERVKDQ+ Sbjct: 4 IPNVLAERYASAAMKSIWSAEGRIILEREFWIAVMKAQKDLGLDIPDGVIEAYERVKDQV 63 Query: 66 NLASIMKRERVTRHDVKARIEEFCELAGHEHLHKGMTSRDLTENVEQLQVYRALQLIETK 125 NL SI RERVTRHDVKARIEEFCELAG EH+HKGMTSRDLTENVEQLQ+++++Q+I K Sbjct: 64 NLPSIDARERVTRHDVKARIEEFCELAGCEHIHKGMTSRDLTENVEQLQIWKSMQIIRDK 123 Query: 126 SVAALIRFATRAKQLRDIPFTARTHNVAAQVTTLGKRIAMSGEEMLLAHQSLVNVLQTYP 185 +VA L R + A+Q + + RTHNVAAQ TT+GKR+AM GE+++ + ++++ Y Sbjct: 124 AVAVLNRMSALAEQWKHVTIAGRTHNVAAQTTTMGKRVAMFGEDIVHGLGAWISLMDRYS 183 Query: 186 ARGLKGAVGTRLDQITLFNGDAGKARALEQRVLVHLGLPKVLDAVGQVYPRSLDFRAVSV 245 RGLKGAVGT+LDQ++LF DA + LE RV HLG+P VGQVYPRSLDF VS Sbjct: 184 VRGLKGAVGTQLDQLSLFGQDAVRVLELEDRVCAHLGIPAKWMNVGQVYPRSLDFSVVSG 243 Query: 246 LTELASGPGNFAKTIRLMAGHELASEGFAKGQVGSSAMPHKMNSRSCERINGLHVILKGY 305 L EL SG +FAKT+RLMAGHELA+EGFAKGQ GSSAMPHKMN+RSCER+NG HVILKG+ Sbjct: 244 LVELTSGCSSFAKTLRLMAGHELATEGFAKGQTGSSAMPHKMNARSCERVNGFHVILKGF 303 Query: 306 LAMAAGLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLETLLTVLDQMEVFEAVVETELN 365 L M +GLAGDQWNEGDVSCSVVRRV++PD+F A DGL ET LTVL+QM V+EAVV EL Sbjct: 304 LMMISGLAGDQWNEGDVSCSVVRRVVMPDSFYAADGLFETFLTVLNQMGVYEAVVAAELR 363 Query: 366 RYLPFLLTTTVMMEAVKKGAGREGAHEAIKEHAVAAIGDLRTGKIVQNDLLQRLAADKRL 425 RYLPFL+TTT++MEAVK+G GRE AHE IKEHAVA DLR GKI++N+LL RLA D RL Sbjct: 364 RYLPFLMTTTILMEAVKRGIGRETAHEVIKEHAVAVSNDLRAGKIMENNLLDRLAEDGRL 423 Query: 426 GLSEAELQHVLDQGRANSGDAGAQVDFFAEQVEALAKAKPEAARYNPGTIL 476 G+ A+LQ + D + +G A AQV+ F V+ + P+ A Y PG IL Sbjct: 424 GIDRADLQRIFDSNSSATGMADAQVEAFRSMVKEVTDRFPDGAGYQPGDIL 474 >ref|ZP_03724706.1| adenylosuccinate lyase [Opitutaceae bacterium TAV2] gb|EEG21282.1| adenylosuccinate lyase [Opitutaceae bacterium TAV2] Length = 473 Score = 583 bits (1503), Expect = e-164, Method: Compositional matrix adjust. Identities = 295/471 (62%), Positives = 346/471 (73%), Gaps = 1/471 (0%) Query: 6 ISNVLAERYASPAMRAIWSGEGKVRLERDYWIAVLKAQRDLGIAVPDGVIESYERVKDQI 65 I NVLAERYASP ++ +WS G++ LERDYWIAV+KAQRDLG+ +P I YERVK+QI Sbjct: 4 IPNVLAERYASPLIKDLWSPAGRIALERDYWIAVMKAQRDLGLPIPAKTIADYERVKNQI 63 Query: 66 NLASIMKRERVTRHDVKARIEEFCELAGHEHLHKGMTSRDLTENVEQLQVYRALQLIETK 125 +LASI RERVT HDVKARIEEF LAGHE +H G+TSRDLTENVEQLQ+ R+L ++ K Sbjct: 64 DLASIDARERVTLHDVKARIEEFNGLAGHESIHLGLTSRDLTENVEQLQIARSLAVVRLK 123 Query: 126 SVAALIRFATRAKQLRDIPFTARTHNVAAQVTTLGKRIAMSGEEMLLAHQSLVNVLQTYP 185 + AAL++ + RA+Q RD+ T RTHNV AQ TTLGKR AMSG+E+L A + + YP Sbjct: 124 TAAALVKLSRRARQYRDLMITGRTHNVPAQPTTLGKRFAMSGQELLAAFTRIDELTTRYP 183 Query: 186 ARGLKGAVGTRLDQITLFNGDAGKARALEQRVLVHLGLPKVLDAVGQVYPRSLDFRAVSV 245 RGLKGAVGT+LDQ+TLF GDA K LE RVL HLG L AVGQVYPRSLDF VS Sbjct: 184 VRGLKGAVGTQLDQLTLFAGDAAKVARLEARVLKHLGFHVSLFAVGQVYPRSLDFEVVSA 243 Query: 246 LTELASGPGNFAKTIRLMAGHELASEGFAKGQVGSSAMPHKMNSRSCERINGLHVILKGY 305 L + + +FA T+RLMAG L +EGF KGQVGSSAMPHK+N+R+CERI G IL GY Sbjct: 244 LHQTGAAASSFATTLRLMAGQGLLTEGFQKGQVGSSAMPHKVNARNCERICGFSTILSGY 303 Query: 306 LAMAAGLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLETLLTVLDQMEVFEAVVETELN 365 + M LAGDQWNEGDVSCSVVRRV LPDAF A+DGLLETLL VL+QM+VFEA + E Sbjct: 304 VTMTGALAGDQWNEGDVSCSVVRRVALPDAFYAIDGLLETLLAVLNQMDVFEAAIAAENE 363 Query: 366 RYLPFLLTTTVMMEAVKKGAGREGAHEAIKEHAVAAIGDLRTGKIVQNDLLQRLAADKRL 425 R LPFL TTT+MMEAVK GAGRE AH AIKEHA+AA +RTGK DL+ L+AD RL Sbjct: 364 RQLPFLATTTIMMEAVKAGAGRETAHAAIKEHALAAARAIRTGK-GDTDLVNLLSADARL 422 Query: 426 GLSEAELQHVLDQGRANSGDAGAQVDFFAEQVEALAKAKPEAARYNPGTIL 476 GL+ A L +L + G A QVD F V A+AK AARY PG +L Sbjct: 423 GLTRARLSAILADAKRFVGAAPQQVDTFVRTVAAIAKKVKGAARYEPGKLL 473 >ref|ZP_07718377.1| adenylosuccinate lyase [Aeromicrobium marinum DSM 15272] gb|EFQ82113.1| adenylosuccinate lyase [Aeromicrobium marinum DSM 15272] Length = 479 Score = 573 bits (1477), Expect = e-161, Method: Compositional matrix adjust. Identities = 288/469 (61%), Positives = 347/469 (73%) Query: 8 NVLAERYASPAMRAIWSGEGKVRLERDYWIAVLKAQRDLGIAVPDGVIESYERVKDQINL 67 NVLA RYASP + I+S E K+ LER WIAVLKAQRDLG+A PDGV+E+YE V DQ++L Sbjct: 11 NVLAHRYASPQVATIFSPEHKIVLERQLWIAVLKAQRDLGVATPDGVVEAYEAVVDQVDL 70 Query: 68 ASIMKRERVTRHDVKARIEEFCELAGHEHLHKGMTSRDLTENVEQLQVYRALQLIETKSV 127 SI RER+TRHDVKARIEEFC LAG EH+HKGMTSRDLTENVEQLQV AL+++ ++V Sbjct: 71 ESIAARERITRHDVKARIEEFCALAGTEHIHKGMTSRDLTENVEQLQVRAALEVVRGRAV 130 Query: 128 AALIRFATRAKQLRDIPFTARTHNVAAQVTTLGKRIAMSGEEMLLAHQSLVNVLQTYPAR 187 AAL R A + ++ R+HNVAAQ TTLGKR A +E+L A + + ++L YP R Sbjct: 131 AALARLGRLAGEHAELVMAGRSHNVAAQATTLGKRFATVADELLAAVERVDDLLVRYPLR 190 Query: 188 GLKGAVGTRLDQITLFNGDAGKARALEQRVLVHLGLPKVLDAVGQVYPRSLDFRAVSVLT 247 G+KG VGT DQ+ L GDA K LEQRV HLG +VL +VGQVYPRSLD+ V+ L Sbjct: 191 GIKGPVGTSQDQLDLLGGDASKLAELEQRVAAHLGFSRVLTSVGQVYPRSLDYDVVTALA 250 Query: 248 ELASGPGNFAKTIRLMAGHELASEGFAKGQVGSSAMPHKMNSRSCERINGLHVILKGYLA 307 +L + P N A TIRLMAG+EL +EGF GQVGSSAMPHKMN+RSCER+NGL VIL+G+++ Sbjct: 251 QLVAAPSNLATTIRLMAGNELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLAVILRGHVS 310 Query: 308 MAAGLAGDQWNEGDVSCSVVRRVMLPDAFLAMDGLLETLLTVLDQMEVFEAVVETELNRY 367 M LAGDQWNEGDVSCSVVRRV LPDAF A DGL ET LTVLD+ VF AVV+ EL+RY Sbjct: 311 MLGELAGDQWNEGDVSCSVVRRVALPDAFYAADGLFETFLTVLDEFGVFPAVVQRELDRY 370 Query: 368 LPFLLTTTVMMEAVKKGAGREGAHEAIKEHAVAAIGDLRTGKIVQNDLLQRLAADKRLGL 427 LPFL TT V+M AV+ GAGRE AHEA+KEHAVA +R +NDL RLAAD RLGL Sbjct: 371 LPFLATTKVLMAAVRHGAGREVAHEAVKEHAVAVALGMREKGAAENDLFARLAADDRLGL 430 Query: 428 SEAELQHVLDQGRANSGDAGAQVDFFAEQVEALAKAKPEAARYNPGTIL 476 +E +L ++ +G A +QV ++EAL A+PEAA Y PG+IL Sbjct: 431 TETDLVTLVAAPVEFTGAAVSQVGAVVARIEALTAAEPEAAAYVPGSIL 479