BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0013.p (498 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004110541.1| diguanylate cyclase [Rhodopseudomonas palust... 253 4e-65 ref|YP_001993488.1| diguanylate cyclase [Rhodopseudomonas palust... 251 2e-64 ref|NP_949331.1| putative diguanylate cyclase [Rhodopseudomonas ... 250 5e-64 ref|YP_486137.1| diguanylate cyclase [Rhodopseudomonas palustris... 249 1e-63 ref|YP_782245.1| diguanylate cyclase [Rhodopseudomonas palustris... 243 6e-62 >ref|YP_004110541.1| diguanylate cyclase [Rhodopseudomonas palustris DX-1] gb|ADU45808.1| diguanylate cyclase [Rhodopseudomonas palustris DX-1] Length = 359 Score = 253 bits (647), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 136/300 (45%), Positives = 193/300 (64%), Gaps = 8/300 (2%) Query: 190 DIVRASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFWEVSEEEVARH--PAYIT 247 ++ A L+ L AL+NV+ G+++L+ +L ++ N + + + E R P Y Sbjct: 27 ELAEARQALETLYAALDNVDAGLLILNEELRAVYSNPVLHVMFRANSAEEIRQNRPLYAE 86 Query: 248 LLTRNRRAVPADATPEQIRAFPAKRIAEIKAGDHK-RDVQTPDGRNIRIHCSTMANGGRM 306 +L + +AV D + + ++R+A +++GD K D+ DG+ +R H + + +GGRM Sbjct: 87 MLAASAQAVAVD-----LDDYVSRRLAWVQSGDPKPMDLAMTDGKALRCHLAVLPSGGRM 141 Query: 307 LTFVDVTDLVRNARQLEVLATTDPLTGLFNRRHFLTTLDAEWSRFQRYYRSVSVLMVDID 366 L + DVTD+VRNA +LE LATTD +TG++NRRHFLT D EW+R +RY R +S LM+DID Sbjct: 142 LIYSDVTDIVRNAEELERLATTDGMTGVYNRRHFLTLADREWARARRYQRPMSFLMIDID 201 Query: 367 HFKSINDRFGHAAGDEAIKAVAGICIRGKRKSDVVGRVGGEEFAVLLPETTLSRARTVAE 426 +FK+IND FGH GDE I +A + KR DV+ R+GGEEFA+LLPET L++A+ VAE Sbjct: 202 YFKAINDGFGHQVGDEMIVHLARLARDCKRDCDVLARLGGEEFALLLPETDLAQAQVVAE 261 Query: 427 RIRKRAEALSFRADDRLVPLTVSIGVAEALTSMPGIDALMKAADAALYQAKEHGRNRTEC 486 R+R+ A + R +P TVSIGVA AL M + LMKAAD ALY AK GRNR C Sbjct: 262 RLRREVAANALVVASRSIPATVSIGVATALPGMDDVSELMKAADQALYDAKHAGRNRVIC 321 Score = 81.3 bits (199), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 44/128 (34%), Positives = 72/128 (56%), Gaps = 7/128 (5%) Query: 76 LRAALDQIPVGILLLGSELKALFINRAFRSMWALPDA--VADRNPTFTDLMHHGCKTMAY 133 L AALD + G+L+L EL+A++ N M+ A + P + +++ + +A Sbjct: 38 LYAALDNVDAGLLILNEELRAVYSNPVLHVMFRANSAEEIRQNRPLYAEMLAASAQAVAV 97 Query: 134 ELPAEQLHAYLAERVRLVSVGDPNPIDLRRSNGDVVRCQCTPLPDGGRMVSYTPVTDIVR 193 +L Y++ R+ V GDP P+DL ++G +RC LP GGRM+ Y+ VTDIVR Sbjct: 98 DL-----DDYVSRRLAWVQSGDPKPMDLAMTDGKALRCHLAVLPSGGRMLIYSDVTDIVR 152 Query: 194 ASDQLKVL 201 +++L+ L Sbjct: 153 NAEELERL 160 >ref|YP_001993488.1| diguanylate cyclase [Rhodopseudomonas palustris TIE-1] gb|ACF03013.1| diguanylate cyclase [Rhodopseudomonas palustris TIE-1] Length = 345 Score = 251 bits (641), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 137/306 (44%), Positives = 189/306 (61%), Gaps = 8/306 (2%) Query: 190 DIVRASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFWEVSEEEVARH--PAYIT 247 ++ A L+ L AL+NV+ G+++L+ +L ++ N + + + E R P Y Sbjct: 27 ELAEARQALETLYAALDNVDAGLLILNEELRAVYSNPVLHVMFRANSAEEIRQNRPLYAE 86 Query: 248 LLTRNRRAVPADATPEQIRAFPAKRIAEIKAGDHK-RDVQTPDGRNIRIHCSTMANGGRM 306 +L A A A + + ++R+A +++GD K D+ DG +R H + + GGRM Sbjct: 87 ML-----AASAQAVAVNLEDYVSRRLAWVQSGDPKPMDLAMTDGTALRCHLAVLPGGGRM 141 Query: 307 LTFVDVTDLVRNARQLEVLATTDPLTGLFNRRHFLTTLDAEWSRFQRYYRSVSVLMVDID 366 L + DVTD+VRNA +LE LATTD +TG++NRRHFLT D EWSR +RY R +S LM+DID Sbjct: 142 LIYSDVTDIVRNAEELERLATTDGMTGVYNRRHFLTLADREWSRARRYERPMSFLMIDID 201 Query: 367 HFKSINDRFGHAAGDEAIKAVAGICIRGKRKSDVVGRVGGEEFAVLLPETTLSRARTVAE 426 +FK+IND FGH GDE I +A + KR DV+ R+GGEEFA+LLPET L++A VAE Sbjct: 202 YFKAINDGFGHQVGDEMIVHLARLARDCKRDCDVLARLGGEEFALLLPETDLAQAEVVAE 261 Query: 427 RIRKRAEALSFRADDRLVPLTVSIGVAEALTSMPGIDALMKAADAALYQAKEHGRNRTEC 486 R+R+ + +P TVSIGVA AL SM + LMKAAD ALY AK GRNR C Sbjct: 262 RLRREVAGNALVVASHAIPATVSIGVATALPSMKDVSDLMKAADQALYDAKHAGRNRVIC 321 Query: 487 WSPPSP 492 + P Sbjct: 322 RACHDP 327 Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 50/161 (31%), Positives = 85/161 (52%), Gaps = 9/161 (5%) Query: 43 QQANAAAPAPAAPAPAAIPERRSGDILRGHMLALRAALDQIPVGILLLGSELKALFINRA 102 ++ + +A +P P A + +R R + L AALD + G+L+L EL+A++ N Sbjct: 7 EETHHSAGSPEEPEIAGL--QRELAEARQALETLYAALDNVDAGLLILNEELRAVYSNPV 64 Query: 103 FRSMWALPDA--VADRNPTFTDLMHHGCKTMAYELPAEQLHAYLAERVRLVSVGDPNPID 160 M+ A + P + +++ + +A L Y++ R+ V GDP P+D Sbjct: 65 LHVMFRANSAEEIRQNRPLYAEMLAASAQAVAV-----NLEDYVSRRLAWVQSGDPKPMD 119 Query: 161 LRRSNGDVVRCQCTPLPDGGRMVSYTPVTDIVRASDQLKVL 201 L ++G +RC LP GGRM+ Y+ VTDIVR +++L+ L Sbjct: 120 LAMTDGTALRCHLAVLPGGGRMLIYSDVTDIVRNAEELERL 160 >ref|NP_949331.1| putative diguanylate cyclase [Rhodopseudomonas palustris CGA009] emb|CAE29435.1| putative diguanylate cyclase (GGDEF) [Rhodopseudomonas palustris CGA009] Length = 382 Score = 250 bits (638), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 136/306 (44%), Positives = 188/306 (61%), Gaps = 8/306 (2%) Query: 190 DIVRASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFWEVSEEEVARH--PAYIT 247 ++ A L+ L AL+NV+ G+++L+ +L ++ N + + + E R P Y Sbjct: 64 ELAEARQALETLYAALDNVDAGLLILNEELRAVYSNPVLHVMFRANSAEEIRQNRPLYAE 123 Query: 248 LLTRNRRAVPADATPEQIRAFPAKRIAEIKAGDHK-RDVQTPDGRNIRIHCSTMANGGRM 306 +L A A A + + ++R+A +++GD K D+ DG +R H + + GGRM Sbjct: 124 ML-----AASAQAVAVNLEDYVSRRLAWVQSGDPKPMDLAMTDGTALRCHLAVLPGGGRM 178 Query: 307 LTFVDVTDLVRNARQLEVLATTDPLTGLFNRRHFLTTLDAEWSRFQRYYRSVSVLMVDID 366 L + DVTD+VRNA +LE LATTD +TG++NRRHFLT D EWSR +RY R +S LM+DID Sbjct: 179 LIYSDVTDIVRNAEELERLATTDGMTGVYNRRHFLTLADREWSRARRYERPMSFLMIDID 238 Query: 367 HFKSINDRFGHAAGDEAIKAVAGICIRGKRKSDVVGRVGGEEFAVLLPETTLSRARTVAE 426 +FK+IND FGH GDE I +A + KR DV+ R+GGEEFA+LLPET L++A VAE Sbjct: 239 YFKAINDGFGHQVGDEMIVHLARLARDCKRDCDVLARLGGEEFALLLPETDLAQAEVVAE 298 Query: 427 RIRKRAEALSFRADDRLVPLTVSIGVAEALTSMPGIDALMKAADAALYQAKEHGRNRTEC 486 R+R+ + +P TVSIGVA AL M + LMKAAD ALY AK GRNR C Sbjct: 299 RLRREVAGNALVVASHAIPATVSIGVATALPGMKDVSDLMKAADQALYDAKHAGRNRVIC 358 Query: 487 WSPPSP 492 + P Sbjct: 359 RACHDP 364 Score = 81.3 bits (199), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 16/197 (8%) Query: 14 QLLLVGSNQVKPCKRLWQSDRQL----GLAFEE---QQANAAAPAPAAPAPAAIPERRSG 66 ++LL S+ V C+ L G+ + ++ + +A +P P A + R Sbjct: 8 EMLLCNSSVVVRCRATRGVSESLARPGGVTMHKRLTEETHHSAGSPEQPEIAGL--HREL 65 Query: 67 DILRGHMLALRAALDQIPVGILLLGSELKALFINRAFRSMWALPDA--VADRNPTFTDLM 124 R + L AALD + G+L+L EL+A++ N M+ A + P + +++ Sbjct: 66 AEARQALETLYAALDNVDAGLLILNEELRAVYSNPVLHVMFRANSAEEIRQNRPLYAEML 125 Query: 125 HHGCKTMAYELPAEQLHAYLAERVRLVSVGDPNPIDLRRSNGDVVRCQCTPLPDGGRMVS 184 + +A L Y++ R+ V GDP P+DL ++G +RC LP GGRM+ Sbjct: 126 AASAQAVAV-----NLEDYVSRRLAWVQSGDPKPMDLAMTDGTALRCHLAVLPGGGRMLI 180 Query: 185 YTPVTDIVRASDQLKVL 201 Y+ VTDIVR +++L+ L Sbjct: 181 YSDVTDIVRNAEELERL 197 >ref|YP_486137.1| diguanylate cyclase [Rhodopseudomonas palustris HaA2] gb|ABD07226.1| diguanylate cyclase [Rhodopseudomonas palustris HaA2] Length = 350 Score = 249 bits (635), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 142/308 (46%), Positives = 195/308 (63%), Gaps = 9/308 (2%) Query: 194 ASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFWEVSEEEVARH--PAYITLLTR 251 AS L+ L AL+NV+ G+++L+++L ++ N + + + E R P Y +L Sbjct: 35 ASQALETLYAALDNVDSGLLILNKELRAVYSNPILHVMFRANSCEEIRQTRPFYADMLAA 94 Query: 252 NRRAVPADATPEQIRAFPAKRIAEIKAGDHK-RDVQTPDGRNIRIHCSTMANGGRMLTFV 310 +AV D + + A+R+A +++GD K D+ DG+ +R H + + +GGRML + Sbjct: 95 AAQAVAVD-----LDDYVARRLAWVQSGDPKPMDLAMIDGKALRCHLAVLPDGGRMLIYS 149 Query: 311 DVTDLVRNARQLEVLATTDPLTGLFNRRHFLTTLDAEWSRFQRYYRSVSVLMVDIDHFKS 370 DVTD+VRNA +LE LATTD +TG+FNRRHFLT D EW+R +RY R +S LM+DIDHFKS Sbjct: 150 DVTDIVRNAEELERLATTDGMTGIFNRRHFLTLADREWARARRYGRPLSCLMIDIDHFKS 209 Query: 371 INDRFGHAAGDEAIKAVAGICIRGKRKSDVVGRVGGEEFAVLLPETTLSRARTVAERIRK 430 IND FGH GD+ I +A + KR DV+ R+GGEEFA+LLPET L +A VAER+R Sbjct: 210 INDDFGHQVGDDMIVHLAKLARDCKRDCDVLARIGGEEFALLLPETDLPQALAVAERLRG 269 Query: 431 RAEALSFRADDRLVPLTVSIGVAEALTSMPGIDALMKAADAALYQAKEHGRNRTECW-SP 489 A S V TVSIG A + ++ GI LM+AAD ALY+AK GRNR C SP Sbjct: 270 EVAASSLLMASGSVRATVSIGAATSAATIDGISDLMRAADRALYEAKHGGRNRVVCHVSP 329 Query: 490 PSPPKLAA 497 + P +AA Sbjct: 330 DAVPSVAA 337 Score = 79.0 bits (193), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 57/172 (33%), Positives = 87/172 (50%), Gaps = 22/172 (12%) Query: 76 LRAALDQIPVGILLLGSELKALFINRAFRSMWALP--DAVADRNPTFTDLMHHGCKTMAY 133 L AALD + G+L+L EL+A++ N M+ + + P + D++ + +A Sbjct: 42 LYAALDNVDSGLLILNKELRAVYSNPILHVMFRANSCEEIRQTRPFYADMLAAAAQAVAV 101 Query: 134 ELPAEQLHAYLAERVRLVSVGDPNPIDLRRSNGDVVRCQCTPLPDGGRMVSYTPVTDIVR 193 +L Y+A R+ V GDP P+DL +G +RC LPDGGRM+ Y+ VTDIVR Sbjct: 102 DL-----DDYVARRLAWVQSGDPKPMDLAMIDGKALRCHLAVLPDGGRMLIYSDVTDIVR 156 Query: 194 ASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFWEVSEEEVARHPAY 245 +++L+ L DG+ T NR R F +++ E AR Y Sbjct: 157 NAEELERLA-----TTDGM--------TGIFNR--RHFLTLADREWARARRY 193 >ref|YP_782245.1| diguanylate cyclase [Rhodopseudomonas palustris BisA53] gb|ABJ07265.1| diguanylate cyclase [Rhodopseudomonas palustris BisA53] Length = 349 Score = 243 bits (620), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 134/296 (45%), Positives = 188/296 (63%), Gaps = 8/296 (2%) Query: 194 ASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFWEVSEEEVARH--PAYITLLTR 251 A L+ L AL+NV+ G+++L++DL ++ N + + + E R P Y +L Sbjct: 34 ARQSLETLYAALDNVDAGLLILNQDLRAVYSNPVLHVMFRANSAEEIREKRPLYAEMLAA 93 Query: 252 NRRAVPADATPEQIRAFPAKRIAEIKAGD-HKRDVQTPDGRNIRIHCSTMANGGRMLTFV 310 +AV D + + A+R+A +++GD + D+ DG +R H + + +GGRML + Sbjct: 94 AAQAVAVD-----LDDYVARRLAWVQSGDPNPMDLAMTDGTALRCHLAVLPSGGRMLIYS 148 Query: 311 DVTDLVRNARQLEVLATTDPLTGLFNRRHFLTTLDAEWSRFQRYYRSVSVLMVDIDHFKS 370 DVTD+VR+A+ LE LATTD +TG++NRRHFLT D EW+R +RY R +S LM+DID+FKS Sbjct: 149 DVTDIVRHAQDLERLATTDGMTGVYNRRHFLTLADREWARARRYGRPISFLMIDIDYFKS 208 Query: 371 INDRFGHAAGDEAIKAVAGICIRGKRKSDVVGRVGGEEFAVLLPETTLSRARTVAERIRK 430 IND FGH GDE I +A + KR+ DV+ R+GGEEFA+LLPET L +A+ +AER+R Sbjct: 209 INDGFGHHVGDEMIVHLANLARDCKRECDVLARIGGEEFALLLPETDLPQAQIIAERLRA 268 Query: 431 RAEALSFRADDRLVPLTVSIGVAEALTSMPGIDALMKAADAALYQAKEHGRNRTEC 486 A + +P TVSIGVA + +M I LMKAAD ALY AK GRNR C Sbjct: 269 EVAAKALVVASGSIPATVSIGVATSAAAMNDISDLMKAADQALYDAKHAGRNRVIC 324 Score = 80.5 bits (197), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 62/193 (32%), Positives = 96/193 (49%), Gaps = 23/193 (11%) Query: 55 PAPAAIPERRSGDILRGHMLALRAALDQIPVGILLLGSELKALFINRAFRSMWALPDA-- 112 PA A +R D R + L AALD + G+L+L +L+A++ N M+ A Sbjct: 21 PADLARLQRELSDA-RQSLETLYAALDNVDAGLLILNQDLRAVYSNPVLHVMFRANSAEE 79 Query: 113 VADRNPTFTDLMHHGCKTMAYELPAEQLHAYLAERVRLVSVGDPNPIDLRRSNGDVVRCQ 172 + ++ P + +++ + +A +L Y+A R+ V GDPNP+DL ++G +RC Sbjct: 80 IREKRPLYAEMLAAAAQAVAVDLDD-----YVARRLAWVQSGDPNPMDLAMTDGTALRCH 134 Query: 173 CTPLPDGGRMVSYTPVTDIVRASDQLKVLTGALENVEDGVVLLDRDLNTIFLNRRMRDFW 232 LP GGRM+ Y+ VTDIVR + L+ L DG+ T NR R F Sbjct: 135 LAVLPSGGRMLIYSDVTDIVRHAQDLERLA-----TTDGM--------TGVYNR--RHFL 179 Query: 233 EVSEEEVARHPAY 245 +++ E AR Y Sbjct: 180 TLADREWARARRY 192