BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0056.p (344 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_769902.1| cobalamin synthesis protein [Bradyrhizobium jap... 558 e-157 ref|ZP_08663953.1| cobalamin biosynthesis protein CobW [Paracocc... 523 e-146 ref|YP_916314.1| cobalamin biosynthesis protein CobW [Paracoccus... 513 e-143 ref|ZP_08643860.1| cobalamin synthesis protein CobW [Acetobacter... 505 e-141 ref|ZP_05079060.1| cobalamin biosynthesis protein CobW [Rhodobac... 494 e-138 >ref|NP_769902.1| cobalamin synthesis protein [Bradyrhizobium japonicum USDA 110] dbj|BAC48527.1| cobalamin synthesis protein [Bradyrhizobium japonicum USDA 110] Length = 349 Score = 558 bits (1437), Expect = e-157, Method: Compositional matrix adjust. Identities = 303/344 (88%), Positives = 319/344 (92%) Query: 1 MTTLAKIPVTVVTGFLGSGKTTLIQHLIRNANGKKLAVLVNEFGSEGVDGDILKSCADAN 60 M +LAK+PVTVVTGFLGSGKTTLIQHL+ N NGKKLAVLVNEFGSEGVDG ILKSCADAN Sbjct: 1 MNSLAKVPVTVVTGFLGSGKTTLIQHLLANPNGKKLAVLVNEFGSEGVDGQILKSCADAN 60 Query: 61 CPAENIVELANGCICCTVADDFIPAMEQLLARNVKPDHIVIETSGLALPKPLLKAFDWPE 120 CP ENIVELANGCICCTVADDFIP ME LLAR V+PDHI+IETSGLALPKPLL+AFDWPE Sbjct: 61 CPEENIVELANGCICCTVADDFIPTMELLLARPVRPDHILIETSGLALPKPLLRAFDWPE 120 Query: 121 IRSRITVDGVIALADAEAVAAGRFAPDPAAVDAQRAADDNLDHETPLSEVFEDQIACADL 180 IRSRITVDGVIALADAEAVAAGRFAPDPAAV+AQRAAD+NLDHETPLSEVFEDQIACAD+ Sbjct: 121 IRSRITVDGVIALADAEAVAAGRFAPDPAAVEAQRAADENLDHETPLSEVFEDQIACADI 180 Query: 181 VLLTKADLAGAEGIKAAKAVIAAEMPREVPMLPVVDGTIDARVILGLEAAAENDLAARPS 240 VLLTKADLAG G++AAKA I AEMPR VPML V DG IDARVILGL AAAENDLAARPS Sbjct: 181 VLLTKADLAGPAGLEAAKAAITAEMPRRVPMLAVTDGAIDARVILGLGAAAENDLAARPS 240 Query: 241 HHDGEEEHEHDDFNSVVIDLPEVSDVDALVASIKGLAREQNVLRAKGYIAVEGKPMRLLV 300 HHDGEEEHEHDDF SVVIDLPEV DVDALVAS++ LAREQNVLRAKGYIAV GKPMRLL+ Sbjct: 241 HHDGEEEHEHDDFASVVIDLPEVGDVDALVASVQRLAREQNVLRAKGYIAVAGKPMRLLL 300 Query: 301 QSVGERVRHQFDMPWGARARQSKLVVIGEHADIDEAAIRARLGV 344 Q+VGERVRHQFD PWGA ARQSKLVVIGEH DIDEAAIRA LG+ Sbjct: 301 QAVGERVRHQFDKPWGALARQSKLVVIGEHGDIDEAAIRAGLGL 344 >ref|ZP_08663953.1| cobalamin biosynthesis protein CobW [Paracoccus sp. TRP] Length = 344 Score = 523 bits (1346), Expect = e-146, Method: Compositional matrix adjust. Identities = 265/343 (77%), Positives = 304/343 (88%) Query: 1 MTTLAKIPVTVVTGFLGSGKTTLIQHLIRNANGKKLAVLVNEFGSEGVDGDILKSCADAN 60 MT L K PVTV+TGFLG+GKTTLI+HL++N GK+LAVLVNEFG+ GVDG+ILKSCAD N Sbjct: 1 MTDLTKTPVTVITGFLGAGKTTLIRHLMQNPQGKRLAVLVNEFGTMGVDGEILKSCADEN 60 Query: 61 CPAENIVELANGCICCTVADDFIPAMEQLLARNVKPDHIVIETSGLALPKPLLKAFDWPE 120 CPAENI+EL+NGCICCTVADDFIP +E+L+A V+PDHI+IETSGLALPKPLLKAFDWP Sbjct: 61 CPAENIMELSNGCICCTVADDFIPTLERLMAMPVRPDHILIETSGLALPKPLLKAFDWPA 120 Query: 121 IRSRITVDGVIALADAEAVAAGRFAPDPAAVDAQRAADDNLDHETPLSEVFEDQIACADL 180 IRSRITVDGVIALADAEAVAAGRFAPD AAV+AQRAADD+LDHETPLSEVFEDQIACAD+ Sbjct: 121 IRSRITVDGVIALADAEAVAAGRFAPDVAAVEAQRAADDSLDHETPLSEVFEDQIACADI 180 Query: 181 VLLTKADLAGAEGIKAAKAVIAAEMPREVPMLPVVDGTIDARVILGLEAAAENDLAARPS 240 VLL+KADLAG +G+ AA+AVI AE PR++P+LP+VDG ID RVILGL AAAE+DLAARPS Sbjct: 181 VLLSKADLAGEQGLAAARAVIEAEAPRKLPILPLVDGVIDPRVILGLNAAAEDDLAARPS 240 Query: 241 HHDGEEEHEHDDFNSVVIDLPEVSDVDALVASIKGLAREQNVLRAKGYIAVEGKPMRLLV 300 HHDG E+HEHDDF+SVVI+L E++D L I+ LAREQN+LR KG++AV GKPMRLLV Sbjct: 241 HHDGAEDHEHDDFDSVVIELAEIADPADLATRIERLAREQNILRVKGHVAVLGKPMRLLV 300 Query: 301 QSVGERVRHQFDMPWGARARQSKLVVIGEHADIDEAAIRARLG 343 Q+VGERVRHQ+D PWG R S+LVVI EH DIDEAAIRA L Sbjct: 301 QAVGERVRHQYDRPWGDAPRNSRLVVIAEHDDIDEAAIRAVLA 343 >ref|YP_916314.1| cobalamin biosynthesis protein CobW [Paracoccus denitrificans PD1222] gb|ABL70618.1| cobalamin biosynthesis protein CobW [Paracoccus denitrificans PD1222] Length = 344 Score = 513 bits (1321), Expect = e-143, Method: Compositional matrix adjust. Identities = 261/342 (76%), Positives = 299/342 (87%) Query: 1 MTTLAKIPVTVVTGFLGSGKTTLIQHLIRNANGKKLAVLVNEFGSEGVDGDILKSCADAN 60 M+ L K PVTV+TGFLG+GKTTLI+HL+ GK+LAVLVNEFG+ GVDG+ILKSCAD N Sbjct: 1 MSDLTKTPVTVITGFLGAGKTTLIRHLMSQPQGKRLAVLVNEFGTMGVDGEILKSCADEN 60 Query: 61 CPAENIVELANGCICCTVADDFIPAMEQLLARNVKPDHIVIETSGLALPKPLLKAFDWPE 120 CPAENI+EL+NGCICCTVADDFIP +E+L+A VKPDHI+IETSGLALPKPLLKAFDWP Sbjct: 61 CPAENIMELSNGCICCTVADDFIPTLERLMAMPVKPDHILIETSGLALPKPLLKAFDWPA 120 Query: 121 IRSRITVDGVIALADAEAVAAGRFAPDPAAVDAQRAADDNLDHETPLSEVFEDQIACADL 180 IRSRITVDGVIALADAEAVAAGRFAPD AAV+AQRA D +LDHETPLSEVFEDQIACAD+ Sbjct: 121 IRSRITVDGVIALADAEAVAAGRFAPDEAAVEAQRATDPSLDHETPLSEVFEDQIACADI 180 Query: 181 VLLTKADLAGAEGIKAAKAVIAAEMPREVPMLPVVDGTIDARVILGLEAAAENDLAARPS 240 VLL+KADLAG G+ AA+AVI AE PR++P+LP+ DG ID RVILGL AAAE+DLAARPS Sbjct: 181 VLLSKADLAGENGLAAARAVIEAEAPRKLPILPLTDGVIDPRVILGLGAAAEDDLAARPS 240 Query: 241 HHDGEEEHEHDDFNSVVIDLPEVSDVDALVASIKGLAREQNVLRAKGYIAVEGKPMRLLV 300 HHDG ++HEHDDF+SVVI+L E++D L A I+ LAREQN+LR KG++AV GKPMRLLV Sbjct: 241 HHDGADDHEHDDFDSVVIELAEIADPSDLAARIERLAREQNILRVKGHVAVAGKPMRLLV 300 Query: 301 QSVGERVRHQFDMPWGARARQSKLVVIGEHADIDEAAIRARL 342 Q+VGERVRHQ+D PWG R S+LVVI EH DIDEAAIRA L Sbjct: 301 QAVGERVRHQYDRPWGDGPRASRLVVIAEHDDIDEAAIRAVL 342 >ref|ZP_08643860.1| cobalamin synthesis protein CobW [Acetobacter tropicalis NBRC 101654] dbj|GAA07164.1| cobalamin synthesis protein CobW [Acetobacter tropicalis NBRC 101654] Length = 360 Score = 505 bits (1301), Expect = e-141, Method: Compositional matrix adjust. Identities = 242/340 (71%), Positives = 290/340 (85%) Query: 3 TLAKIPVTVVTGFLGSGKTTLIQHLIRNANGKKLAVLVNEFGSEGVDGDILKSCADANCP 62 TL KIPVT++TGFLG+GKTTLI+HL+ + G++LAVLVNEFG+ GVDG+ILKSCAD NCP Sbjct: 13 TLEKIPVTIITGFLGAGKTTLIRHLMSHPQGRRLAVLVNEFGTLGVDGEILKSCADENCP 72 Query: 63 AENIVELANGCICCTVADDFIPAMEQLLARNVKPDHIVIETSGLALPKPLLKAFDWPEIR 122 AENI+ELANGCICCTVADDFIP +E+L+A +PDHI+IETSGLALPKPLLKAFDWP IR Sbjct: 73 AENILELANGCICCTVADDFIPTVERLMALPERPDHILIETSGLALPKPLLKAFDWPTIR 132 Query: 123 SRITVDGVIALADAEAVAAGRFAPDPAAVDAQRAADDNLDHETPLSEVFEDQIACADLVL 182 SRITVDGVI LADAEAVA GRFAPD AVDAQR ADD+LDH+TPL+EVFEDQ+ACADLVL Sbjct: 133 SRITVDGVITLADAEAVAEGRFAPDTEAVDAQRQADDSLDHDTPLAEVFEDQLACADLVL 192 Query: 183 LTKADLAGAEGIKAAKAVIAAEMPREVPMLPVVDGTIDARVILGLEAAAENDLAARPSHH 242 LTKADL + A+ +I + R +P++P+ DGTID +V+LGL A AENDLAARPSHH Sbjct: 193 LTKADLVDETCLNRARDMINSLTSRTLPIIPIKDGTIDPQVVLGLNAQAENDLAARPSHH 252 Query: 243 DGEEEHEHDDFNSVVIDLPEVSDVDALVASIKGLAREQNVLRAKGYIAVEGKPMRLLVQS 302 DGE++HEH+DF+SVVIDLPEV+D ALV +++ LAR Q++LR KGY+AV GKPMR+++Q Sbjct: 253 DGEDDHEHEDFDSVVIDLPEVTDPAALVDAVRSLARTQHILRVKGYVAVVGKPMRMVLQG 312 Query: 303 VGERVRHQFDMPWGARARQSKLVVIGEHADIDEAAIRARL 342 VGERVR Q+D PWG ARQ++LVVI EH +D AAIRA L Sbjct: 313 VGERVRTQYDRPWGKEARQTRLVVIAEHDHVDAAAIRAML 352 >ref|ZP_05079060.1| cobalamin biosynthesis protein CobW [Rhodobacterales bacterium Y4I] gb|EDZ47039.1| cobalamin biosynthesis protein CobW [Rhodobacterales bacterium Y4I] Length = 344 Score = 494 bits (1273), Expect = e-138, Method: Compositional matrix adjust. Identities = 252/343 (73%), Positives = 297/343 (86%) Query: 1 MTTLAKIPVTVVTGFLGSGKTTLIQHLIRNANGKKLAVLVNEFGSEGVDGDILKSCADAN 60 M+ L KIPVTV+TGFLG+GKTTLI+HL++N GK+LAV+VNEFG+ GVDGDILKSCAD N Sbjct: 1 MSDLNKIPVTVITGFLGAGKTTLIRHLMQNPQGKRLAVVVNEFGTAGVDGDILKSCADEN 60 Query: 61 CPAENIVELANGCICCTVADDFIPAMEQLLARNVKPDHIVIETSGLALPKPLLKAFDWPE 120 CPAENI+ELANGCICCTVADDFIP +EQL+ KPDHIVIETSGLALPKPLLKAFDWP Sbjct: 61 CPAENIMELANGCICCTVADDFIPTIEQLMNLPEKPDHIVIETSGLALPKPLLKAFDWPA 120 Query: 121 IRSRITVDGVIALADAEAVAAGRFAPDPAAVDAQRAADDNLDHETPLSEVFEDQIACADL 180 IRSRITVDGVIALADAEAVA G+FAPD AV AQR AD ++DHETPLSEVFEDQI+CAD+ Sbjct: 121 IRSRITVDGVIALADAEAVAKGQFAPDLDAVQAQREADGSIDHETPLSEVFEDQISCADI 180 Query: 181 VLLTKADLAGAEGIKAAKAVIAAEMPREVPMLPVVDGTIDARVILGLEAAAENDLAARPS 240 VLL+KADLAG G++ A+AVI AE PR++P+LP+ +G ID R+ILGL AAAE+DL ARPS Sbjct: 181 VLLSKADLAGDAGVEKARAVIEAEAPRKLPILPMSEGVIDPRIILGLNAAAEDDLEARPS 240 Query: 241 HHDGEEEHEHDDFNSVVIDLPEVSDVDALVASIKGLAREQNVLRAKGYIAVEGKPMRLLV 300 HHDG +HEHDDF S+V+++ EVSD +AL +I LARE+N+LR KGY+AVEGKPMR+LV Sbjct: 241 HHDGHHDHEHDDFESIVVEMGEVSDPEALQNAIVKLARERNILRVKGYVAVEGKPMRMLV 300 Query: 301 QSVGERVRHQFDMPWGARARQSKLVVIGEHADIDEAAIRARLG 343 Q+VGER+R Q+D PWGA+ R++ LVVI EH DIDE AIRA LG Sbjct: 301 QAVGERLRAQYDQPWGAQPRKTALVVIAEHDDIDEQAIRAELG 343