BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0016.p (416 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001203872.1| D-3-phosphoglycerate dehydrogenase [Bradyrhi... 738 0.0 ref|YP_001238166.1| D-3-phosphoglycerate dehydrogenase [Bradyrhi... 734 0.0 ref|YP_001770580.1| NAD-binding D-isomer specific 2-hydroxyacid ... 636 e-180 ref|YP_002498117.1| NAD-binding D-isomer specific 2-hydroxyacid ... 621 e-176 ref|YP_001755127.1| NAD-binding D-isomer specific 2-hydroxyacid ... 617 e-174 >ref|YP_001203872.1| D-3-phosphoglycerate dehydrogenase [Bradyrhizobium sp. ORS 278] emb|CAL75635.1| D-3-phosphoglycerate dehydrogenase (PGDH) [Bradyrhizobium sp. ORS 278] Length = 415 Score = 738 bits (1904), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/413 (86%), Positives = 386/413 (93%) Query: 2 LSLPKTKIRVLLLEGVNESAARMFEANGYTELQRLPKALGPKELRQALSGIHMLGIRSRT 61 LSLPK KIRVLLLEGVN+SA RMFEA+GYTE++RLPKALG EL++ LSG+HMLGIRSRT Sbjct: 3 LSLPKQKIRVLLLEGVNDSAVRMFEASGYTEVERLPKALGSAELKRMLSGVHMLGIRSRT 62 Query: 62 QLTADIMEAADRLLVVGCFSVGTNQVDLDAARKLGIPVFNAPYSNTRSVAELTIAEIVML 121 LTAD+++AADRL+ VGCFSVGTNQVDLDAAR+LGIPVFNAPYSNTRSVAELTIAE+VML Sbjct: 63 NLTADVLQAADRLMAVGCFSVGTNQVDLDAARRLGIPVFNAPYSNTRSVAELTIAEVVML 122 Query: 122 FRRIFPRSVSAHAGGWDKSAEGSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIYFDQT 181 RRIFPRSVSAHAGGWDKSA GSREVRGKTLGI+GYGNIGSQLSNLAEAMGMRVI+FD T Sbjct: 123 MRRIFPRSVSAHAGGWDKSANGSREVRGKTLGIIGYGNIGSQLSNLAEAMGMRVIFFDLT 182 Query: 182 DKLRHGNTEPAESLDALLAASDVVSLHVPETPATANMIGAAQLQLMKPEAYLINNSRGTV 241 DKLRHGNTEP ESLD LLA SDVVSLHVPETPATANMIG Q++ MK AYLINNSRGTV Sbjct: 183 DKLRHGNTEPVESLDELLANSDVVSLHVPETPATANMIGERQIRHMKDGAYLINNSRGTV 242 Query: 242 VDLDALAGALREGRLAGAAVDVFPVEPVSNEARFVSPLQGLPNVILTPHVGGSTEEAQDR 301 VD+DALA ALREG+L+GAAVDVFPVEP SN FVSPLQGLPNVILTPHVGGSTEEAQDR Sbjct: 243 VDIDALASALREGKLSGAAVDVFPVEPASNADPFVSPLQGLPNVILTPHVGGSTEEAQDR 302 Query: 302 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVMRQVNDAVSRHG 361 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGV+RQVN+AVSRH Sbjct: 303 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVLRQVNEAVSRHN 362 Query: 362 INILAQYLQTDPEVGYVVLETDVVGGEGEGLLADLKGIDGTIRVRVLYDQNRP 414 INILAQYLQTDPEVGYVVLETDVVGGEGE LL++L+ +DGTIRVRVLYD +RP Sbjct: 363 INILAQYLQTDPEVGYVVLETDVVGGEGEELLSELRAVDGTIRVRVLYDHDRP 415 >ref|YP_001238166.1| D-3-phosphoglycerate dehydrogenase [Bradyrhizobium sp. BTAi1] gb|ABQ34260.1| D-3-phosphoglycerate dehydrogenase (PGDH) [Bradyrhizobium sp. BTAi1] Length = 415 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/413 (86%), Positives = 386/413 (93%) Query: 2 LSLPKTKIRVLLLEGVNESAARMFEANGYTELQRLPKALGPKELRQALSGIHMLGIRSRT 61 LSLPK KIRVLLLEGVN+SA RMFEANGYTE++RLPKALG EL++ LSG+HMLGIRSRT Sbjct: 3 LSLPKQKIRVLLLEGVNDSAVRMFEANGYTEIERLPKALGSAELKRMLSGVHMLGIRSRT 62 Query: 62 QLTADIMEAADRLLVVGCFSVGTNQVDLDAARKLGIPVFNAPYSNTRSVAELTIAEIVML 121 LT D+++AADRL+VVGCFSVGTNQVDLDAA++LGIPVFNAPYSNTRSVAELTIAE+VML Sbjct: 63 HLTEDVLQAADRLMVVGCFSVGTNQVDLDAAKRLGIPVFNAPYSNTRSVAELTIAEVVML 122 Query: 122 FRRIFPRSVSAHAGGWDKSAEGSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIYFDQT 181 RRIFPRSV+AHAGGWDKSA GSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVI+FD T Sbjct: 123 MRRIFPRSVAAHAGGWDKSANGSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIFFDLT 182 Query: 182 DKLRHGNTEPAESLDALLAASDVVSLHVPETPATANMIGAAQLQLMKPEAYLINNSRGTV 241 DKLRHGNTEP ESLD LLA SDVVSLHVPETPATANMIG Q++ MK AYLINNSRGTV Sbjct: 183 DKLRHGNTEPVESLDELLAMSDVVSLHVPETPATANMIGERQIRHMKDGAYLINNSRGTV 242 Query: 242 VDLDALAGALREGRLAGAAVDVFPVEPVSNEARFVSPLQGLPNVILTPHVGGSTEEAQDR 301 VD++ALA ALR+G+LAGAAVDVFPVEP SN FVSPLQGLPNVILTPHVGGSTEEAQDR Sbjct: 243 VDIEALASALRDGKLAGAAVDVFPVEPASNADPFVSPLQGLPNVILTPHVGGSTEEAQDR 302 Query: 302 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVMRQVNDAVSRHG 361 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGV+RQVN+AVSRH Sbjct: 303 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVLRQVNEAVSRHN 362 Query: 362 INILAQYLQTDPEVGYVVLETDVVGGEGEGLLADLKGIDGTIRVRVLYDQNRP 414 INILAQYLQTDPEVGYVVLETDVVGGEGE LL++L+ ++GTIRVRVLYD +RP Sbjct: 363 INILAQYLQTDPEVGYVVLETDVVGGEGEELLSELRAVEGTIRVRVLYDHDRP 415 >ref|YP_001770580.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Methylobacterium sp. 4-46] gb|ACA18146.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Methylobacterium sp. 4-46] Length = 415 Score = 636 bits (1641), Expect = e-180, Method: Compositional matrix adjust. Identities = 311/410 (75%), Positives = 350/410 (85%) Query: 2 LSLPKTKIRVLLLEGVNESAARMFEANGYTELQRLPKALGPKELRQALSGIHMLGIRSRT 61 LSLPK KIRVLLLEG+N+SA + A GYT + RL KAL P +LR+AL G H+LGIRSRT Sbjct: 5 LSLPKDKIRVLLLEGINDSAVSLLNAAGYTNVTRLAKALDPADLREALRGTHLLGIRSRT 64 Query: 62 QLTADIMEAADRLLVVGCFSVGTNQVDLDAARKLGIPVFNAPYSNTRSVAELTIAEIVML 121 QL EAADRL+ VGCFSVGTNQVDL AAR+ GIPVFNAP+SNTRSVAEL I EIVML Sbjct: 65 QLDEGAFEAADRLIAVGCFSVGTNQVDLQAARRRGIPVFNAPFSNTRSVAELVIGEIVML 124 Query: 122 FRRIFPRSVSAHAGGWDKSAEGSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIYFDQT 181 RRI PRSVSAHAGGWDKSA S EVRGKTLGIVGYGNIGSQLSNLAEAMGMRVI++D T Sbjct: 125 LRRIVPRSVSAHAGGWDKSAANSFEVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIFYDLT 184 Query: 182 DKLRHGNTEPAESLDALLAASDVVSLHVPETPATANMIGAAQLQLMKPEAYLINNSRGTV 241 D+LRHGNTEP E+LD LL SDVVSLHVPETPAT MIG AQ++ MKP AYLINNSRGTV Sbjct: 185 DRLRHGNTEPVETLDDLLGQSDVVSLHVPETPATHTMIGEAQIRAMKPGAYLINNSRGTV 244 Query: 242 VDLDALAGALREGRLAGAAVDVFPVEPVSNEARFVSPLQGLPNVILTPHVGGSTEEAQDR 301 VDLDALAGALR+G L GAAVDVFPVEP SN+ RFVSPLQGL NVILTPHVGGSTEEAQ+R Sbjct: 245 VDLDALAGALRDGHLRGAAVDVFPVEPKSNQERFVSPLQGLENVILTPHVGGSTEEAQER 304 Query: 302 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVMRQVNDAVSRHG 361 IG EVARKL+DYSD+GSTFGAVNFPQVQL ARP GTR+IHV RN+PG++R++ND +R G Sbjct: 305 IGAEVARKLVDYSDIGSTFGAVNFPQVQLAARPLGTRYIHVQRNIPGMLRRLNDVFARQG 364 Query: 362 INILAQYLQTDPEVGYVVLETDVVGGEGEGLLADLKGIDGTIRVRVLYDQ 411 INI AQ+ QTD EVGYVV+ETD V G+ E LL +++ ++GTIR R+LY++ Sbjct: 365 INIAAQFYQTDGEVGYVVIETDAVEGDAEALLEEIRQLEGTIRARLLYER 414 >ref|YP_002498117.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Methylobacterium nodulans ORS 2060] gb|ACL57814.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Methylobacterium nodulans ORS 2060] Length = 414 Score = 621 bits (1602), Expect = e-176, Method: Compositional matrix adjust. Identities = 303/410 (73%), Positives = 349/410 (85%), Gaps = 1/410 (0%) Query: 2 LSLPKTKIRVLLLEGVNESAARMFEANGYTELQRLPKALGPKELRQALSGIHMLGIRSRT 61 LSLPK KIRVLLLEG+N+SA + A GYT + RL KALGP +L +AL G H+LGIRSRT Sbjct: 5 LSLPKDKIRVLLLEGINDSAVMLLNAAGYTNVTRLSKALGPTDLHEALKGTHILGIRSRT 64 Query: 62 QLTADIMEAADRLLVVGCFSVGTNQVDLDAARKLGIPVFNAPYSNTRSVAELTIAEIVML 121 QL +EAADRL+ VGCFSVGTNQVDL+AAR+ GIP+FNAP+SNTRSVAEL I EIVML Sbjct: 65 QLDEAALEAADRLIAVGCFSVGTNQVDLEAARRRGIPIFNAPFSNTRSVAELVIGEIVML 124 Query: 122 FRRIFPRSVSAHAGGWDKSAEGSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIYFDQT 181 RRI PRSVSAHAGGWDKSA S EVRGKTLGIVGYGNIGSQLSNLAEAMGMRVI+FD T Sbjct: 125 LRRIVPRSVSAHAGGWDKSAANSFEVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIFFDLT 184 Query: 182 DKLRHGNTEPAESLDALLAASDVVSLHVPETPATANMIGAAQLQLMKPEAYLINNSRGTV 241 D+LRHGNTEP ++L+ LLA SDVVSLHVPETPAT MIG AQ++ MKP AYLINNSRGTV Sbjct: 185 DRLRHGNTEPVDTLEELLAQSDVVSLHVPETPATHTMIGEAQIRAMKPGAYLINNSRGTV 244 Query: 242 VDLDALAGALREGRLAGAAVDVFPVEPVSNEARFVSPLQGLPNVILTPHVGGSTEEAQDR 301 VDL+ALA ALR+G L GAAVDVFPVEP SN RF SPLQGL NVILTPHVGGSTEEAQ+R Sbjct: 245 VDLEALASALRDGHLRGAAVDVFPVEPKSNHERFTSPLQGLENVILTPHVGGSTEEAQER 304 Query: 302 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVMRQVNDAVSRHG 361 IG EVARKL+DYSD+GST GAVNFPQVQL ARP GTR+IHV RN+PG++R++ND + +G Sbjct: 305 IGSEVARKLVDYSDIGSTVGAVNFPQVQLAARPLGTRYIHVQRNIPGMLRRLNDVFASNG 364 Query: 362 INILAQYLQTDPEVGYVVLETDVVGGEGEGLLADLKGIDGTIRVRVLYDQ 411 INI AQ+ QTD EVGYVV+ETD + G+ + LL +++ ++GTIR R+LY++ Sbjct: 365 INIAAQFYQTDGEVGYVVIETDAL-GDADALLEEIRELEGTIRARLLYER 413 >ref|YP_001755127.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Methylobacterium radiotolerans JCM 2831] gb|ACB24444.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Methylobacterium radiotolerans JCM 2831] Length = 416 Score = 617 bits (1592), Expect = e-174, Method: Compositional matrix adjust. Identities = 305/410 (74%), Positives = 344/410 (83%) Query: 2 LSLPKTKIRVLLLEGVNESAARMFEANGYTELQRLPKALGPKELRQALSGIHMLGIRSRT 61 LSLPK KIRVLLLEG+N+SA + A GYT L RLPKAL + L +AL G+HM+GIRSRT Sbjct: 6 LSLPKDKIRVLLLEGINDSAVALMRAAGYTNLTRLPKALDREALHEALQGVHMVGIRSRT 65 Query: 62 QLTADIMEAADRLLVVGCFSVGTNQVDLDAARKLGIPVFNAPYSNTRSVAELTIAEIVML 121 QL A EAADRLL VGCFSVGTNQVDL+AAR GIPVFNAP+SNTRSVAELTI EIVML Sbjct: 66 QLDAAAFEAADRLLAVGCFSVGTNQVDLEAARHRGIPVFNAPFSNTRSVAELTIGEIVML 125 Query: 122 FRRIFPRSVSAHAGGWDKSAEGSREVRGKTLGIVGYGNIGSQLSNLAEAMGMRVIYFDQT 181 RRI PRSV AHAG WDKSA GS EVRGKTLGIVGYGNIG+QLS LAEAMGMRV+++D T Sbjct: 126 LRRIVPRSVGAHAGRWDKSAAGSLEVRGKTLGIVGYGNIGTQLSTLAEAMGMRVLFYDHT 185 Query: 182 DKLRHGNTEPAESLDALLAASDVVSLHVPETPATANMIGAAQLQLMKPEAYLINNSRGTV 241 DKLRHGNTEP E+L LLA SDVVSLHVPET ATANMIGAA+++ MK A+LINN+RGTV Sbjct: 186 DKLRHGNTEPVETLHDLLAQSDVVSLHVPETDATANMIGAAEIRAMKAGAFLINNARGTV 245 Query: 242 VDLDALAGALREGRLAGAAVDVFPVEPVSNEARFVSPLQGLPNVILTPHVGGSTEEAQDR 301 VDL+ALA ALR+G L GAAVDVFPVEP SN FVSPLQGL NVILTPH+GGSTEEAQ+R Sbjct: 246 VDLEALAAALRDGHLKGAAVDVFPVEPGSNAEPFVSPLQGLENVILTPHIGGSTEEAQER 305 Query: 302 IGGEVARKLIDYSDVGSTFGAVNFPQVQLPARPTGTRFIHVHRNVPGVMRQVNDAVSRHG 361 IG EVARKL+DYSD+GST GAVNFPQVQLPARPTGTRFIHV RN+PG++ ++ND SR Sbjct: 306 IGSEVARKLVDYSDIGSTVGAVNFPQVQLPARPTGTRFIHVQRNLPGMLGRLNDVFSRGH 365 Query: 362 INILAQYLQTDPEVGYVVLETDVVGGEGEGLLADLKGIDGTIRVRVLYDQ 411 +NI AQ+ QTD EVGYVVLETD + E LL +++ I GTIR R+LY++ Sbjct: 366 VNIAAQFYQTDGEVGYVVLETDATDADAEALLTEIRAIPGTIRARLLYER 415