BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0006.p (227 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001683515.1| TetR family transcriptional regulator [Caulo... 161 7e-38 ref|YP_004552810.1| regulatory protein TetR [Sphingobium chlorop... 145 6e-33 ref|ZP_00955821.1| regulatory protein, TetR [Sulfitobacter sp. E... 137 1e-30 ref|ZP_00997612.1| regulatory protein, TetR [Oceanicola batsensi... 133 3e-29 ref|YP_761472.1| TetR family transcriptional regulator [Hyphomon... 129 2e-28 >ref|YP_001683515.1| TetR family transcriptional regulator [Caulobacter sp. K31] gb|ABZ71017.1| transcriptional regulator, TetR family [Caulobacter sp. K31] Length = 204 Score = 161 bits (408), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 80/202 (39%), Positives = 126/202 (62%), Gaps = 2/202 (0%) Query: 12 SEETRNQIKAAAQMLFARHGVDAVTVQQIVDAGGQRNNAALHYHFGSKEELIRQMVVDGA 71 ++ R+ IK AAQ LFA GVDAV+V+ I+ A G RN A+LHY+FGSK++L+ Q+V+DGA Sbjct: 3 ADIARDAIKRAAQSLFAARGVDAVSVRDILTATGHRNGASLHYYFGSKDDLVAQLVIDGA 62 Query: 72 TVLDGRRREMLDEIEARGGPKSIREVLLVLVMPVIELGDDERWHGYIRFTTNLQASDPKA 131 ++D RR LD +EA GGP S+REV+ VL++P +LG D Y+RF + + A Sbjct: 63 RLIDDRRNARLDALEADGGPHSLREVMEVLILPSTDLGRDGGEGDYLRFISTFSLQNRAA 122 Query: 132 LRDALNGRWNASYVACFNYLKTMLRLPAPIVEQRLSIFAIYANAILSAHEAAVESRNTKS 191 + WN Y C ++++ + P ++E+RL ++ AI++A EAA+ + + Sbjct: 123 FDAIVGDGWNRGYQRCLDHIRRLAAAPPEVLERRLVFLSLGLRAIMTAREAALAAHPDHA 182 Query: 192 SRLWGQPFTIENILDTLEATLT 213 WG P T+E++++TL +T Sbjct: 183 --FWGPPATLEDLVETLVGLVT 202 >ref|YP_004552810.1| regulatory protein TetR [Sphingobium chlorophenolicum L-1] gb|AEG48304.1| regulatory protein TetR [Sphingobium chlorophenolicum L-1] Length = 253 Score = 145 bits (365), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 81/212 (38%), Positives = 125/212 (58%), Gaps = 9/212 (4%) Query: 7 TTRASSEETRNQIKAAAQMLFARHGVDAVTVQQIVDAGGQRNNAALHYHFGSKEELIRQM 66 +RA++ E QIK A LFA GVD VTV++I A GQ+N+ A+ Y+FGSKE L+R + Sbjct: 26 ASRAAAPE---QIKKVALRLFAEKGVDGVTVREIAAAAGQKNHGAVGYYFGSKEALVRAI 82 Query: 67 VVDGATVLDGRRREMLDEIEARGGPKSIREVLLVLVMPVIELGDDERWHGYIRFTTNLQA 126 V+DGA LD R LD +E +GGP++IREV+ +++ PV+ L D+ Y++F Sbjct: 83 VMDGAVALDRERNLALDLLEEKGGPRAIREVVDIVIDPVLGLPDEH----YVQFILLFAM 138 Query: 127 SDPKALRDALNGRWNASYVACFNYL-KTMLRLPAPIVEQRLSIFAIYANAILSAHEAAVE 185 + + + DAL+ WN++Y C +L + M LP + QR Y +A+LSA + A+ Sbjct: 139 THREMMMDALDPAWNSAYGRCLAHLRRFMPHLPPALQNQRFIFMGAYISAVLSARQRALA 198 Query: 186 SRNTKSSRLWGQPFTIENILDTLEATLTCPLS 217 R ++ +WG T+E+ +L A L P+ Sbjct: 199 DR-SRDHPMWGSEGTLEHFKQSLGALLEAPVD 229 >ref|ZP_00955821.1| regulatory protein, TetR [Sulfitobacter sp. EE-36] gb|EAP83472.1| regulatory protein, TetR [Sulfitobacter sp. EE-36] Length = 212 Score = 137 bits (345), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 69/165 (41%), Positives = 96/165 (58%), Gaps = 1/165 (0%) Query: 18 QIKAAAQMLFARHGVDAVTVQQIVDAGGQRNNAALHYHFGSKEELIRQMVVDGATVLDGR 77 ++K AQ LFA G+D VTV+ I A GQ+N AA+ YHFGSKE LIR+++VDGA ++D R Sbjct: 15 RLKGEAQRLFANRGIDGVTVRDIAKAAGQKNPAAVGYHFGSKEALIRELIVDGAKIIDAR 74 Query: 78 RREMLDEIEARGGPKSIREVLLVLVMPVIELGDDERWHGYIRFTTNLQASDPKALRDALN 137 R LD +EA GGP I +++ +L+ P + L D Y RF L S DAL Sbjct: 75 RNAQLDALEADGGPTRISQIVDILIYPSVNLAADGETDTYNRFLHMLTMSHRVLFDDALE 134 Query: 138 GRWNASYVACFNYLKTMLRLPAPIVE-QRLSIFAIYANAILSAHE 181 GRWN+ Y C +L+ ++ + ++ QR Y +LSA E Sbjct: 135 GRWNSGYQRCLEHLRILMPSQSRTIQNQRFIFLESYLGGVLSARE 179 >ref|ZP_00997612.1| regulatory protein, TetR [Oceanicola batsensis HTCC2597] gb|EAQ04679.1| regulatory protein, TetR [Oceanicola batsensis HTCC2597] Length = 234 Score = 133 bits (334), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 78/223 (34%), Positives = 125/223 (56%), Gaps = 11/223 (4%) Query: 1 MSSRRRTTRA---SSEETRNQIKAAAQMLFARHGVDAVTVQQIVDAGGQRNNAALHYHFG 57 M+ R+RT + +E +IK AA LF+ G+D VTV+QIV G RNNA+LHY+FG Sbjct: 1 MAQRQRTEDSRHDQAESAAERIKDAALKLFSARGIDGVTVRQIVAEAGARNNASLHYYFG 60 Query: 58 SKEELIRQMVVDGATVLDGRRREMLDEIEARGGPKSIREVLLVLV------MPVIELGDD 111 SK+ L+R ++++ A + D R LDEIEA GGP+ + E++ ++V V G Sbjct: 61 SKDALVRALILECAHLSDSARIRRLDEIEAAGGPREVAEIIRLIVEVETTPRGVGSGGAM 120 Query: 112 ERWHGYIRFTTNLQASDPKALRDALNGRWNASYVACFNYLKTML-RLPAPIVEQRLSIFA 170 G++RF LQ ++ + AL G N+ Y+ C +++ +L +P ++ QRL Sbjct: 121 GASSGHMRFVMGLQINNRRVFMQALTGHRNSGYLRCIDHIYRLLPGIPKSVLNQRLIFMD 180 Query: 171 IYANAILSAHEAAVESRNTKSSRLWGQPFTIENILDTLEATLT 213 ++ + L+A EAA E ++ +LW IEN++ + LT Sbjct: 181 LFMGSTLAAREAAFE-QDPTGGKLWSSELAIENLIISACGILT 222 >ref|YP_761472.1| TetR family transcriptional regulator [Hyphomonas neptunium ATCC 15444] gb|ABI77995.1| transcriptional regulator, TetR family [Hyphomonas neptunium ATCC 15444] Length = 212 Score = 129 bits (325), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 68/195 (34%), Positives = 111/195 (56%), Gaps = 2/195 (1%) Query: 19 IKAAAQMLFARHGVDAVTVQQIVDAGGQRNNAALHYHFGSKEELIRQMVVDGATVLDGRR 78 +K AA LFA GVD VTV++I A GQRN+ A+ YHFGSK +LIR ++VDGA +++ RR Sbjct: 16 LKRAAMKLFAERGVDGVTVREIAAAAGQRNHGAVGYHFGSKADLIRTLIVDGAKLINDRR 75 Query: 79 REMLDEIEARGGPKSIREVLLVLVMPVIELGDDERWHGYIRFTTNLQASDPKALRDALNG 138 LD +E G P ++ EV ++V P +++ D Y RF + +AL G Sbjct: 76 NAALDALEGVGRPLTLEEVAGIMVYPSVDITPDGEEECYNRFVVLFSMTHRALFMEALGG 135 Query: 139 RWNASYVACFNYLKTML-RLPAPIVEQRLSIFAIYANAILSAHEAAVESRNTKSSRLWGQ 197 +WN+ + C L+ + LP +R+ Y ++L+A EA + + +++ W + Sbjct: 136 QWNSGFKRCLEQLRGFMGHLPRAKQTERIVFLESYLGSVLAAREARL-ADTSRAHPTWSR 194 Query: 198 PFTIENILDTLEATL 212 P T+E+++ T+ A + Sbjct: 195 PATLEHLVTTMVAIV 209