BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0019.p (194 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_770563.1| KHG-KDPG bifunctional aldolase [Bradyrhizobium ... 279 2e-73 ref|ZP_08629184.1| 4-Hydroxy-2-oxoglutarate aldolase/ 2-dehydro-... 246 1e-63 ref|YP_001769915.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4... 203 1e-50 ref|YP_002499715.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4... 192 2e-47 ref|YP_001203915.1| KHG/KDPG aldolase [Bradyrhizobium sp. ORS 27... 182 3e-44 >ref|NP_770563.1| KHG-KDPG bifunctional aldolase [Bradyrhizobium japonicum USDA 110] dbj|BAC49188.1| KHG-KDPG bifunctional aldolase [Bradyrhizobium japonicum USDA 110] Length = 240 Score = 279 bits (713), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 143/216 (66%), Positives = 161/216 (74%), Gaps = 22/216 (10%) Query: 1 MTTTSKQDQIAELIRQATVIPVLTIERLEDAVPLAKX----------------------G 38 MTTT++Q+Q+ L + ATVIPVLTIER++DAVPLA+ Sbjct: 25 MTTTAQQNQLVALFKAATVIPVLTIERIQDAVPLARALVAGGVRTLEVTLRTPVAIEAAR 84 Query: 39 AIIAGVPEAIVGIGTILNGDDLARAEALGAKFGISPGATPELLTAAASSRLPFAPGIATA 98 A++A VPEA+VGIGTILN D R E LG FGISPG TP+LL AA S LPFAPGIATA Sbjct: 85 AMMAEVPEAVVGIGTILNPADFTRVEKLGVAFGISPGLTPDLLKAATDSSLPFAPGIATA 144 Query: 99 SELMQALAHGFDVVKFFPAEQAGGIKALRALAGPFPQVRVCPTGGVSEANAATWLAEPNV 158 SELM AL++GFDV KFFPAEQAGGIK LRAL GPFP VR CPTGGV EANAATWLAEPNV Sbjct: 145 SELMMALSYGFDVAKFFPAEQAGGIKGLRALGGPFPNVRFCPTGGVGEANAATWLAEPNV 204 Query: 159 LAVGGSWLCPAADIRAGNWAGITAMCVTAMKTLKAA 194 +AVGGSWLCP A+IRAGNWAGITA+C +K LK A Sbjct: 205 VAVGGSWLCPTAEIRAGNWAGITAICQRTLKALKGA 240 >ref|ZP_08629184.1| 4-Hydroxy-2-oxoglutarate aldolase/ 2-dehydro-3-deoxyphosphogluconate aldolase [Bradyrhizobiaceae bacterium SG-6C] gb|EGP07677.1| 4-Hydroxy-2-oxoglutarate aldolase/ 2-dehydro-3-deoxyphosphogluconate aldolase [Bradyrhizobiaceae bacterium SG-6C] Length = 219 Score = 246 bits (628), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 128/216 (59%), Positives = 156/216 (72%), Gaps = 26/216 (12%) Query: 1 MTTTSKQDQIAELIRQATVIPVLTIERLEDAVPLAKXGAIIAG----------------- 43 ++ + K + ++ A ++PVLTIER+ED VPLAK A++AG Sbjct: 4 LSASEKHAALETILVPARIVPVLTIERVEDGVPLAK--ALVAGGIKVLEVTFRTHAAAEA 61 Query: 44 -------VPEAIVGIGTILNGDDLARAEALGAKFGISPGATPELLTAAASSRLPFAPGIA 96 VP+AIVG+GT+L+GDDL RAEALGAKF +SPGATPELL AAA S LP PG+A Sbjct: 62 AKAIIAEVPDAIVGMGTVLSGDDLRRAEALGAKFAVSPGATPELLDAAADSALPLLPGVA 121 Query: 97 TASELMQALAHGFDVVKFFPAEQAGGIKALRALAGPFPQVRVCPTGGVSEANAATWLAEP 156 TASE+MQA A GF+++KFFPAEQAGGI LRALAGPFP +R CPTGGV+ N ATWLAE Sbjct: 122 TASEVMQAQARGFNLLKFFPAEQAGGIPMLRALAGPFPAMRFCPTGGVNADNLATWLAET 181 Query: 157 NVLAVGGSWLCPAADIRAGNWAGITAMCVTAMKTLK 192 NV+A GGSWLCPA+DI++GNW ITA CV AMK L+ Sbjct: 182 NVVAAGGSWLCPASDIKSGNWEIITARCVDAMKKLR 217 >ref|YP_001769915.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Methylobacterium sp. 4-46] gb|ACA17481.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Methylobacterium sp. 4-46] Length = 246 Score = 203 bits (517), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 112/209 (53%), Positives = 140/209 (66%), Gaps = 25/209 (11%) Query: 5 SKQDQIAELIRQATVIPVLTIERLEDAVPLAKX----------------------GAIIA 42 ++Q ++ L+ ++ VIPV+T+ L AVPLA+ AI+A Sbjct: 37 TRQARLEALLAESPVIPVITVPELAHAVPLARALVAGGIRTLEITLRTPVARDAARAIMA 96 Query: 43 GVPEAIVGIGTILNGDDLARAEALGAKFGISPGATPELLTAAASSRLPFAPGIATASELM 102 VP+A+VGIGT+L DDL A ALGA+F +SPGATP+LL AAA S L F PG+AT SELM Sbjct: 97 EVPDAVVGIGTVLTPDDLEAARALGARFALSPGATPDLLRAAAESDLAFMPGVATPSELM 156 Query: 103 QALAHGFDVVKFFPAEQAGGIKALRALAGPFPQVRVCPTGGVSEANAATWLAEPNVLAVG 162 Q LA GF + KFFPA AGG AL+ALAGPFPQ R CPTGG++EA+A +WLA PNV+AVG Sbjct: 157 QVLAAGFRIAKFFPAVPAGGQAALKALAGPFPQARFCPTGGIAEADAKSWLALPNVVAVG 216 Query: 163 GSWLCPAADIRAGNWAGITAMCVTAMKTL 191 GSWL P A+IR G + ITA A +TL Sbjct: 217 GSWLAPEAEIREGRFEAITAR---ARRTL 242 >ref|YP_002499715.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Methylobacterium nodulans ORS 2060] gb|ACL59412.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Methylobacterium nodulans ORS 2060] Length = 216 Score = 192 bits (488), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 108/201 (53%), Positives = 130/201 (64%), Gaps = 26/201 (12%) Query: 5 SKQDQIAELIRQATVIPVLTIERLEDAVPLAKXGAIIAG--------------------- 43 S+ ++ L+ A VIPV+T+ L AVPLA+ A++AG Sbjct: 7 SRLARLDALLTDAPVIPVITVPELAQAVPLAR--ALVAGGIRTLEITLRTPVARDAARAI 64 Query: 44 ---VPEAIVGIGTILNGDDLARAEALGAKFGISPGATPELLTAAASSRLPFAPGIATASE 100 VPEA+VGIGT+L DL A LGA+F +SPGATPELL AA+S + F PGIAT SE Sbjct: 65 IAEVPEAVVGIGTVLTPHDLQAAHDLGARFALSPGATPELLREAAASDMAFMPGIATPSE 124 Query: 101 LMQALAHGFDVVKFFPAEQAGGIKALRALAGPFPQVRVCPTGGVSEANAATWLAEPNVLA 160 LMQ L GF + KFFPA AGG AL+ALAGPFPQ R CPTGG+ EA+A WLA PNV+A Sbjct: 125 LMQVLEAGFRIAKFFPAVPAGGQAALKALAGPFPQARFCPTGGIGEADAKAWLALPNVVA 184 Query: 161 VGGSWLCPAADIRAGNWAGIT 181 VGGSWL P A+IRAG + IT Sbjct: 185 VGGSWLAPEAEIRAGRFEAIT 205 >ref|YP_001203915.1| KHG/KDPG aldolase [Bradyrhizobium sp. ORS 278] emb|CAL75678.1| KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase, KHG-aldolase); 2-dehydro-3-deoxy-phosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase, KDPG-aldolase)] [Bradyrhizobium sp. ORS 278] Length = 214 Score = 182 bits (461), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 102/202 (50%), Positives = 125/202 (61%), Gaps = 22/202 (10%) Query: 1 MTTTSKQDQIAELIRQATVIPVLTIERLEDAVPLAKX----------------------G 38 M+ + ++ + A VIPV+TIE AVPLA+ Sbjct: 2 MSNPDNRAKLDAVFALAPVIPVITIEDAAQAVPLARALVAGGLRVIEITLRTQAGFDAAR 61 Query: 39 AIIAGVPEAIVGIGTILNGDDLARAEALGAKFGISPGATPELLTAAASSRLPFAPGIATA 98 AII VPEA VGIGT+L D RA LGA F ISPG + ELL AA+S LPFAPGI T Sbjct: 62 AIIGEVPEAKVGIGTVLTPADYERAAKLGAAFAISPGMSIELLDAASSGDLPFAPGIQTP 121 Query: 99 SELMQALAHGFDVVKFFPAEQAGGIKALRALAGPFPQVRVCPTGGVSEANAATWLAEPNV 158 S+L+ + G+++VKFFPA AGG+ AL ALAGPFP VR CPTGG++ ANAA WLA V Sbjct: 122 SDLIACVTRGYELVKFFPAVPAGGLAALDALAGPFPSVRFCPTGGINAANAAQWLAHKKV 181 Query: 159 LAVGGSWLCPAADIRAGNWAGI 180 +A+GGSW+ PAADI+AG W I Sbjct: 182 VAIGGSWVAPAADIKAGAWVAI 203