BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0037.p (392 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_617401.1| peptidase M19, renal dipeptidase [Sphingopyxis ... 495 e-138 ref|ZP_06862864.1| peptidase M19, renal dipeptidase [Citromicrob... 476 e-132 ref|ZP_08700741.1| peptidase M19, renal dipeptidase [Citromicrob... 470 e-130 ref|YP_498530.1| peptidase M19, renal dipeptidase [Novosphingobi... 459 e-127 ref|YP_459602.1| renal dipeptidase [Erythrobacter litoralis HTCC... 449 e-124 >ref|YP_617401.1| peptidase M19, renal dipeptidase [Sphingopyxis alaskensis RB2256] gb|ABF54068.1| peptidase M19, renal dipeptidase [Sphingopyxis alaskensis RB2256] Length = 393 Score = 495 bits (1275), Expect = e-138, Method: Compositional matrix adjust. Identities = 247/389 (63%), Positives = 300/389 (77%), Gaps = 5/389 (1%) Query: 1 MRKWLSIGLVLIVVALIAAAVRFFTVAPERIDRAQNRVQRVAL-DITPAATALQATLDVA 59 MR+WL I L LIVVAL AA+ FFT+AP I+R NR+ L +T A AL TL + Sbjct: 1 MRRWL-IAL-LIVVAL--AALAFFTLAPGMIERDLNRIDGKPLPQVTARAEALHQTLTIV 56 Query: 60 DMHADSLLWKRDLIARSDRGHIDLPRLIEGHYALQVFSSVTKSPKGQNYDANGADTDTIT 119 D+H+DSLLW RD + R++RGH+DLPRL +GH ALQV +S TKSPKGQNY ANGAD+D IT Sbjct: 57 DLHSDSLLWSRDFLDRAERGHMDLPRLKDGHVALQVLASTTKSPKGQNYHANGADSDNIT 116 Query: 120 NLAIIDLQPPRTWFSLLQRSLWHAEKLHSFAEQSAGRLRLIATPADLDRLLADRKSGATV 179 L I LQP RTW SLL+RSLWHAEKLH A S G L+ +AT ADLD LLA R+ Sbjct: 117 GLVIAQLQPVRTWTSLLERSLWHAEKLHRAAAASNGTLKPVATTADLDALLAARRGKPLT 176 Query: 180 VGGMLSIEGLQDIEGNIGNLDVLYAAGFRMAGLAHFFDNDVAGSMHGVAKGGLTPLGRQV 239 G +LS+EGL ++EG+I NLD LYAAGFRMAGL HFFDN++AGSMHG+ KGGLTPLGRQV Sbjct: 177 TGALLSVEGLHNLEGDIANLDKLYAAGFRMAGLTHFFDNELAGSMHGLKKGGLTPLGRQV 236 Query: 240 VQRMXAMGMIVDLAHASHAAVGEVLAMATRPVVSSHGGVQATCKVNRNLTDDEVRGVART 299 V M A GMIVD+AH S A V ++L MA RPVVSSHGGVQATCKVNRNL+D ++RGVA T Sbjct: 237 VTAMEAKGMIVDIAHCSEACVADILKMARRPVVSSHGGVQATCKVNRNLSDAQIRGVAAT 296 Query: 300 GGVVGIGFWQGAVCSLDPNNVARAIANIRDLVGIDHVGLGSDFDGSTTTSFDASEIVAVT 359 GG+VGIG+W AVC P ++ARA+ ++RDLVGI+HV LGSD+DG+TT FD +++V VT Sbjct: 297 GGLVGIGYWDAAVCDTSPASIARAMKHVRDLVGINHVALGSDYDGATTVRFDTAQLVQVT 356 Query: 360 QALMSRGFSEDDIRKVMGGNVLRVLRAGI 388 QAL+ GFS+D+IR MGGN +RVL+AG+ Sbjct: 357 QALIDAGFSDDEIRAAMGGNAIRVLKAGL 385 >ref|ZP_06862864.1| peptidase M19, renal dipeptidase [Citromicrobium bathyomarinum JL354] Length = 390 Score = 476 bits (1226), Expect = e-132, Method: Compositional matrix adjust. Identities = 230/382 (60%), Positives = 290/382 (75%), Gaps = 2/382 (0%) Query: 9 LVLIVVALIAAAVRFFTVAPERIDRAQNRVQRVAL-DITPAATALQATLDVADMHADSLL 67 L+++ + L+ FF P ++R+ N++ L +++ A AL TL + D+H+D+LL Sbjct: 6 LIIVGLVLLVGIAGFFQFGPGMVERSMNQIDGEPLIEVSDEAKALHETLTIVDLHSDTLL 65 Query: 68 WKRDLIARSDRGHIDLPRLIEGHYALQVFSSVTKSPKGQNYDANGADTDTITNLAIIDLQ 127 W R+L+ R+D+GH+DLPRL EG+ ALQVFSSVTK+PKGQNYDAN AD+D IT L I LQ Sbjct: 66 WNRNLLNRADQGHMDLPRLEEGNVALQVFSSVTKTPKGQNYDANDADSDNITPLVIAQLQ 125 Query: 128 PPRTWFSLLQRSLWHAEKLHSFAEQSAGRLRLIATPADLDRLLADRKSGA-TVVGGMLSI 186 P RTW SLL+RSLWHAEKL A +S G L +A+ DLDRLL +R S VG +LSI Sbjct: 126 PTRTWNSLLERSLWHAEKLDRAAAKSDGELLKVASIKDLDRLLRERSSQTPKPVGALLSI 185 Query: 187 EGLQDIEGNIGNLDVLYAAGFRMAGLAHFFDNDVAGSMHGVAKGGLTPLGRQVVQRMXAM 246 EGLQ++EG++ NLDVL GFRMA L HFFDN +AGSMHG+ KGGLT GR V++M + Sbjct: 186 EGLQNLEGDLSNLDVLSKQGFRMASLTHFFDNTLAGSMHGMEKGGLTDKGRTAVRKMEQL 245 Query: 247 GMIVDLAHASHAAVGEVLAMATRPVVSSHGGVQATCKVNRNLTDDEVRGVARTGGVVGIG 306 GM+VD+AH SH V ++LAMA RPVVSSHGGVQATC VNRNL+DDE+RGVA+TGGVVGIG Sbjct: 246 GMVVDIAHCSHKCVADILAMAERPVVSSHGGVQATCDVNRNLSDDEIRGVAKTGGVVGIG 305 Query: 307 FWQGAVCSLDPNNVARAIANIRDLVGIDHVGLGSDFDGSTTTSFDASEIVAVTQALMSRG 366 +W AVC P + A+A+ ++RDLVGID+V LGSD+DG+TT FD S++V VTQALM G Sbjct: 306 YWDAAVCGTSPRDAAKAMKHVRDLVGIDYVALGSDYDGATTVRFDTSQLVQVTQALMDEG 365 Query: 367 FSEDDIRKVMGGNVLRVLRAGI 388 F+ED+IR VMGGN LRVLRAGI Sbjct: 366 FTEDEIRAVMGGNALRVLRAGI 387 >ref|ZP_08700741.1| peptidase M19, renal dipeptidase [Citromicrobium sp. JLT1363] Length = 405 Score = 470 bits (1210), Expect = e-130, Method: Compositional matrix adjust. Identities = 232/397 (58%), Positives = 295/397 (74%), Gaps = 17/397 (4%) Query: 9 LVLIVVALIAAAVRFFTVAPERIDRAQNRVQRVAL-DITPAATALQATLDVADMHADSLL 67 L++ + L+ FF AP +R+ N++ L +++ A AL TL + D+H+D+LL Sbjct: 6 LIIAGLVLLIGIAGFFQFAPGIAERSMNQIDGEPLIEVSEEAKALHKTLTIVDLHSDTLL 65 Query: 68 WKRDLIARSDRGHIDLPRLIEGHYALQVFSSVTKSPKGQNYDANGADTDTITNLAIIDLQ 127 W R+L+AR+DRGH+DLPRL EG+ ALQVFSSVTK+PKGQNYD+N AD+D IT L I LQ Sbjct: 66 WNRNLLARADRGHMDLPRLEEGNVALQVFSSVTKTPKGQNYDSNDADSDNITTLVIAQLQ 125 Query: 128 PPRTWFSLLQRSLWHAEKLHSFAEQSAGRLRLIATPADLDRLLADR--KS---------- 175 P RTW SLL+RSLWHAEKL A +S G L + + ++D+LLA R KS Sbjct: 126 PTRTWTSLLERSLWHAEKLDRAAAKSDGELVEMTSAEEIDQLLAVRADKSRWPVLKPKFN 185 Query: 176 ----GATVVGGMLSIEGLQDIEGNIGNLDVLYAAGFRMAGLAHFFDNDVAGSMHGVAKGG 231 G VG +LSIEGLQ++EG++ NLD L+ AGFRMA L HFFD D+AGSMHGV KGG Sbjct: 186 TPLRGQPPVGALLSIEGLQNLEGDLANLDKLHEAGFRMASLTHFFDTDLAGSMHGVEKGG 245 Query: 232 LTPLGRQVVQRMXAMGMIVDLAHASHAAVGEVLAMATRPVVSSHGGVQATCKVNRNLTDD 291 LT GR+ V+RM +GM+VD+AH SHA V ++L+M+ RPVVSSHGGVQATCKVNRNLTD+ Sbjct: 246 LTDKGRKAVRRMEELGMVVDIAHCSHACVADILSMSRRPVVSSHGGVQATCKVNRNLTDE 305 Query: 292 EVRGVARTGGVVGIGFWQGAVCSLDPNNVARAIANIRDLVGIDHVGLGSDFDGSTTTSFD 351 E+RGVA+TGGVVGIG+W GAVC P + ARA+ ++RDLVGI+HV LGSD+DG+ T FD Sbjct: 306 EIRGVAKTGGVVGIGYWDGAVCGTSPRDTARAMKHVRDLVGIEHVALGSDYDGAVTVRFD 365 Query: 352 ASEIVAVTQALMSRGFSEDDIRKVMGGNVLRVLRAGI 388 S++V VTQAL+ GF+E++IR VMGGN LRVLRAGI Sbjct: 366 TSQLVQVTQALLDEGFTEEEIRAVMGGNALRVLRAGI 402 >ref|YP_498530.1| peptidase M19, renal dipeptidase [Novosphingobium aromaticivorans DSM 12444] gb|ABD27696.1| peptidase M19, renal dipeptidase [Novosphingobium aromaticivorans DSM 12444] Length = 394 Score = 459 bits (1182), Expect = e-127, Method: Compositional matrix adjust. Identities = 235/393 (59%), Positives = 285/393 (72%), Gaps = 4/393 (1%) Query: 1 MRKWLSIGLVLIVVALIAAAVRFFTVAPERIDRAQNRVQ-RVALDITPAATALQATLDVA 59 MR+ IG +I + L AAA + P +++ N + + L ++ A AL TL + Sbjct: 1 MRR--KIGWAVIFIVLFAAAFVLGPL-PAMVEKRMNVIDGQPLLTVSERAKALHRTLTIV 57 Query: 60 DMHADSLLWKRDLIARSDRGHIDLPRLIEGHYALQVFSSVTKSPKGQNYDANGADTDTIT 119 D+HAD+L+W+R+L R+ +GH+DLPRLI+GH ALQV SSVTKSPKG NYDAN +++DTIT Sbjct: 58 DLHADTLMWRRNLTDRAAQGHVDLPRLIDGHVALQVLSSVTKSPKGLNYDANPSNSDTIT 117 Query: 120 NLAIIDLQPPRTWFSLLQRSLWHAEKLHSFAEQSAGRLRLIATPADLDRLLADRKSGATV 179 LA+ +QP RTW SLL+RSLWHAEKL S+G L + A LD LL +R GA Sbjct: 118 ALAVTQMQPVRTWNSLLERSLWHAEKLDRAVAGSSGELVKVTGQASLDDLLRERGEGALP 177 Query: 180 VGGMLSIEGLQDIEGNIGNLDVLYAAGFRMAGLAHFFDNDVAGSMHGVAKGGLTPLGRQV 239 VG MLSIEGL D+EG NLD LY AGFRMA L HFFDN +AGSMHG KGGLTP GRQ+ Sbjct: 178 VGAMLSIEGLHDLEGKRENLDRLYDAGFRMASLTHFFDNQLAGSMHGERKGGLTPFGRQI 237 Query: 240 VQRMXAMGMIVDLAHASHAAVGEVLAMATRPVVSSHGGVQATCKVNRNLTDDEVRGVART 299 V+ M GMIVD+AH SH V E+LAMA RPVVSSHGGVQATCKVNRNLTD E+RGVART Sbjct: 238 VRAMEDKGMIVDIAHLSHPGVAELLAMARRPVVSSHGGVQATCKVNRNLTDAEIRGVART 297 Query: 300 GGVVGIGFWQGAVCSLDPNNVARAIANIRDLVGIDHVGLGSDFDGSTTTSFDASEIVAVT 359 GGV+GIG+W A+C P ARA+ ++RDLVGI HV LGSDFDG+TTT FD S++ VT Sbjct: 298 GGVIGIGYWDAAICDTSPRAAARAMRHVRDLVGIQHVALGSDFDGATTTRFDTSQLEQVT 357 Query: 360 QALMSRGFSEDDIRKVMGGNVLRVLRAGIAQRG 392 QAL+ GFS+D+IR VMG N LRV+RAGI G Sbjct: 358 QALLDEGFSDDEIRAVMGLNALRVIRAGIVPLG 390 >ref|YP_459602.1| renal dipeptidase [Erythrobacter litoralis HTCC2594] gb|ABC64805.1| renal dipeptidase family protein [Erythrobacter litoralis HTCC2594] Length = 399 Score = 449 bits (1154), Expect = e-124, Method: Compositional matrix adjust. Identities = 217/359 (60%), Positives = 272/359 (75%), Gaps = 2/359 (0%) Query: 32 DRAQNRVQRVAL-DITPAATALQATLDVADMHADSLLWKRDLIARSDRGHIDLPRLIEGH 90 +R NR+ L +++ A AL ATLD+ D+HAD+LLWKR ++ +DRGH+DLPRL G+ Sbjct: 28 ERDMNRIDGKPLPEVSEDAKALHATLDIVDLHADTLLWKRSMVYAADRGHVDLPRLEAGN 87 Query: 91 YALQVFSSVTKSPKGQNYDANGADTDTITNLAIIDLQPPRTWFSLLQRSLWHAEKLHSFA 150 A+QVFSSVTK+P QNYD+N AD D IT LA+ LQP RTW SLL+R+L+HAEKL A Sbjct: 88 VAVQVFSSVTKTPTDQNYDSNSADGDNITLLAVGQLQPVRTWSSLLERTLYHAEKLERAA 147 Query: 151 EQSAGRLRLIATPADLDRLLADRK-SGATVVGGMLSIEGLQDIEGNIGNLDVLYAAGFRM 209 +S G + I TP DLD + R+ G VG +LS+EGL ++EG+ NL+ +Y AG RM Sbjct: 148 RESNGMIIPIETPNDLDGVFGHRRIKGPQFVGALLSVEGLHNLEGDAANLERIYDAGVRM 207 Query: 210 AGLAHFFDNDVAGSMHGVAKGGLTPLGRQVVQRMXAMGMIVDLAHASHAAVGEVLAMATR 269 AGL HFFDN++AGSMHG+ KGGLTP GR +V+RM MGMIVD+AH SH V EVLAMA R Sbjct: 208 AGLTHFFDNELAGSMHGIEKGGLTPFGRNIVRRMEEMGMIVDIAHLSHTGVAEVLAMARR 267 Query: 270 PVVSSHGGVQATCKVNRNLTDDEVRGVARTGGVVGIGFWQGAVCSLDPNNVARAIANIRD 329 PVVSSHGGVQATCKVNRNLTD E+RG+A TGG++G+G+W+GAVC P +A A+ +IRD Sbjct: 268 PVVSSHGGVQATCKVNRNLTDAEIRGLAATGGIIGVGYWEGAVCDTSPKAIAAAMNHIRD 327 Query: 330 LVGIDHVGLGSDFDGSTTTSFDASEIVAVTQALMSRGFSEDDIRKVMGGNVLRVLRAGI 388 LVGI+HV LGSD+DG+ FD S++V VTQALM GFSE +IR VMGGN +RVLR G+ Sbjct: 328 LVGIEHVALGSDYDGAVEVRFDTSKLVQVTQALMDAGFSEREIRAVMGGNAIRVLREGM 386