BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0066.p (290 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08387718.1| histidine kinase-, DNA gyrase B-, and HSP90-l... 230 2e-58 ref|YP_002502723.1| signal transduction histidine kinase [Methyl... 185 6e-45 ref|YP_004674887.1| Signal transduction histidine kinase [Hyphom... 184 1e-44 ref|YP_003756491.1| signal transduction histidine kinase [Hyphom... 171 2e-40 ref|ZP_06888765.1| putative signal transduction histidine kinase... 135 5e-30 >ref|ZP_08387718.1| histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein [Sphingomonas sp. S17] gb|EGI55846.1| histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein [Sphingomonas sp. S17] Length = 326 Score = 230 bits (586), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 125/276 (45%), Positives = 172/276 (62%), Gaps = 5/276 (1%) Query: 9 LDDQLRPDPLMLFIPAIFLASVIFDRGSGFLATGASAALAARYFIPPPPSAAIA-----P 63 L+ L P++LF PA+FL +++FDRGSGF AT SA LAA FI P S I Sbjct: 39 LEGALHNFPILLFYPAVFLCALVFDRGSGFFATILSAFLAAYLFIEPRFSLRIGGENAIA 98 Query: 64 LLIFLASGLCLAGVTEALRTALQKHSEAKAYADVLMMELAHRTRNDLATIMSILRLQARS 123 + IF+ G ++ TE LR + + E++ +L+ ELAHRT+NDLA I S ++LQ+R+ Sbjct: 99 VGIFVLIGFTMSATTEMLRQTIARLDESERAKALLLQELAHRTKNDLAIISSAIQLQSRA 158 Query: 124 DPNPAVQAAITSALARIEVVAKVHDRLRDTPVNSSVDLPAYLEALCGSLSDLHRGVRPIA 183 +P V+ A+ +A AR+ VVA+ +RLR VDL Y+ LC L DL R VRPIA Sbjct: 159 SSHPEVREALDAANARVLVVARAQERLRGDGDGGRVDLAEYIATLCQGLGDLLRDVRPIA 218 Query: 184 IRVSCDEIAVKSSQAASVGLIVNELVTNAFKYAFPEGRPGVVEVDVRKRNEKVVITVRDD 243 +RV+CD I V SS A VGLIVNELVTN+ KYA+P R GV+ V V ++ + V+DD Sbjct: 219 VRVTCDAIDVPSSVAIHVGLIVNELVTNSLKYAYPGERGGVINVTVACAGPEMTVIVKDD 278 Query: 244 GIGCPTEAKSGLGTRLINLMVAQMQGGMTRAPMAQG 279 G+GCP + GLG+RL+ L+ QM G + + +G Sbjct: 279 GVGCPDGVEPGLGSRLVRLLAKQMGGSVRHESVDKG 314 >ref|YP_002502723.1| signal transduction histidine kinase [Methylobacterium nodulans ORS 2060] gb|ACL63284.1| signal transduction histidine kinase [Methylobacterium nodulans ORS 2060] Length = 338 Score = 185 bits (470), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 104/285 (36%), Positives = 162/285 (56%), Gaps = 18/285 (6%) Query: 3 FVAKLLLDDQLRPDPLMLFIPAIFLASVIFDRGSGFLATGASAALAARYFIPPPPSAAIA 62 + ++ L L P++LF AI + +V+FDRG G A SA A + + P S +A Sbjct: 31 LLVRVWLGPHLSGFPVLLFFAAIIVCAVLFDRGCGIYAVLLSAGYVAYFLLSPIYSLKVA 90 Query: 63 P------LLIFLASGLCLAGVTEALRTALQKHSEAKAY-------ADVLMMELAHRTRND 109 L +F+A GL + A + L +EA D+L+ E +HR RND Sbjct: 91 SPSDIVGLFLFVAIGLATVTIIAAFHSTLHNLAEANTRLAASEQEKDLLLREASHRIRND 150 Query: 110 LATIMSILRLQARSDPNPAVQAAITSALARIEVVAKVHDRLRDTPVNSSVDLPAYLEALC 169 L T+M++++LQ R+ + +A + + R++V+A+VH+RLR ++V +L LC Sbjct: 151 LTTLMALVKLQYRTVQDETARAMLAATADRMQVLARVHERLRRDTSKTTVGSYEFLSGLC 210 Query: 170 GSLSDLHRGVRPIAIRVSCDEIAVKSSQAASVGLIVNELVTNAFKYAFPEGRPGVVEVDV 229 L G+RP+ IR ++ A+ +A +VGLI+NE VTNA KYAFP+ RPG++ V Sbjct: 211 NDLRTSMIGLRPVVIRAEVEDHALPQDRAVAVGLILNECVTNAMKYAFPDNRPGIIAVRF 270 Query: 230 RKRNEKVVITVRDDGIGC----PTEAK-SGLGTRLINLMVAQMQG 269 R+ ++ +V+ VRDDG+G P A+ +GLG RLI MVAQ++G Sbjct: 271 RREDDALVLEVRDDGVGVAFDGPERARGTGLGQRLIRSMVAQLEG 315 >ref|YP_004674887.1| Signal transduction histidine kinase [Hyphomicrobium sp. MC1] emb|CCB64313.1| Signal transduction histidine kinase [Hyphomicrobium sp. MC1] Length = 383 Score = 184 bits (468), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 105/287 (36%), Positives = 163/287 (56%), Gaps = 14/287 (4%) Query: 17 PLMLFIPAIFLASVIFDRGSGFLATGASAALAARYFIPPPPSAAI------APLLIFLAS 70 P + FIP +F+ ++FDRG+GFLAT SA +F+ P S I L++F+ Sbjct: 96 PFLTFIPVVFVCGMLFDRGNGFLATILSAMACVFFFLSPHHSLDILQARDQGGLVLFIVI 155 Query: 71 GLCLAGVTEALRTAL----QKHSEAKAYA---DVLMMELAHRTRNDLATIMSILRLQARS 123 G ++ V EAL + L + EA+ D+L+ ELAHRTRND A ++++L LQ+RS Sbjct: 156 GFAISSVVEALHSGLVALAMEKEEARDTVRDRDLLLNELAHRTRNDFANVVTLLNLQSRS 215 Query: 124 DPNPAVQAAITSALARIEVVAKVHDRLRDTPVNSSVDLPAYLEALCGSLSDLHRGVRPIA 183 NP + A+ SA R++ +A+VH RL VD AY+ LC L +RPIA Sbjct: 216 -ANPEAREALASAAERVQTIARVHRRLELQNDRVVVDTRAYIGELCADLRLSRLAMRPIA 274 Query: 184 IRVSCDEIAVKSSQAASVGLIVNELVTNAFKYAFPEGRPGVVEVDVRKRNEKVVITVRDD 243 + + ++ +A +GLI+NE VTNA K+AFPE R G + V R+ + +T+ D+ Sbjct: 275 LDCEVESHSISLEKAVPLGLIINESVTNACKHAFPEQRQGHITVYFRRVGLEYTLTIADN 334 Query: 244 GIGCPTEAKSGLGTRLINLMVAQMQGGMTRAPMAQGCEVEVVVVIES 290 G+G T G+G RL+ ++ AQ+ G ++ P + G V VV+ +++ Sbjct: 335 GVGSETVTNGGIGNRLMGMLAAQLNGDLSFEPRSPGMAVVVVIPVKT 381 >ref|YP_003756491.1| signal transduction histidine kinase [Hyphomicrobium denitrificans ATCC 51888] gb|ADJ24170.1| signal transduction histidine kinase [Hyphomicrobium denitrificans ATCC 51888] Length = 337 Score = 171 bits (432), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 106/284 (37%), Positives = 156/284 (54%), Gaps = 15/284 (5%) Query: 17 PLMLFIPAIFLASVIFDRGSGFLATGASAALAARYFIPPPPSAAIA------PLLIFLAS 70 P ++F+P IF IFDRG+GFLAT SA + + PP S +A L +F+A Sbjct: 49 PYLIFLPVIFACGAIFDRGNGFLATILSATVVDYFMQPPIGSLVVADGDDLIALALFIAL 108 Query: 71 GLCLAGVTEALRTALQ----KHSEAKAYA---DVLMMELAHRTRNDLATIMSILRLQARS 123 G +A V EAL L +H +A +VL+ EL+HRTRNDLA ++++L +QARS Sbjct: 109 GFAMAFVVEALHVGLVDLAIEHQRVQAAVRDREVLLEELSHRTRNDLANVVTLLNMQARS 168 Query: 124 DPNPAVQAAITSALARIEVVAKVHDRLRDTPVNSSVDLPAYLEALCGSLSDLHRGVRPIA 183 A A I SA R++ +A+VH R + VD +Y+ LC L RPIA Sbjct: 169 VDGVARDAMI-SAADRVQAIARVHRRFQIHNHRVVVDTKSYIGELCDDLRLSRLASRPIA 227 Query: 184 IRVSCDEIAVKSSQAASVGLIVNELVTNAFKYAFPEGRPGVVEVDVRKRNEKVVITVRDD 243 ++ + + +A +GLIVNE VTNA K+AFP+ RPG + V + + +T+ D+ Sbjct: 228 LQSEAESHLISIEKAVPLGLIVNECVTNATKHAFPDDRPGAISVRFIRAGDTYTLTITDN 287 Query: 244 GIGCPTE-AKSGLGTRLINLMVAQMQGGMTRAPMAQGCEVEVVV 286 GIG + A +G G+RLI ++ AQ+ + P + G V V + Sbjct: 288 GIGTTADAAHAGTGSRLIQMLAAQLGSKIEIEPRSPGTAVVVTI 331 >ref|ZP_06888765.1| putative signal transduction histidine kinase [Methylosinus trichosporium OB3b] gb|EFH02791.1| putative signal transduction histidine kinase [Methylosinus trichosporium OB3b] Length = 339 Score = 135 bits (341), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 94/307 (30%), Positives = 154/307 (50%), Gaps = 25/307 (8%) Query: 1 LAFVAKLLLDDQLRPDPLMLFIPAIFLASVIFDRGSGFLATGASAALAARYFIPPPPSAA 60 L F +L L ++ P +L +PA ++V+F + SA + YF+ P A Sbjct: 29 LGFFVQLALRQEIPPHFFLLSLPATLFSAVLFGGNPATWSIALSAG-STGYFLLEPQGFA 87 Query: 61 IA------PLLIFLASGLCLAGVTEALRTALQKHSEAKAYA--------------DVLMM 100 I L++F+A+ L L V + L L++ A A A D+L+ Sbjct: 88 IGDRIDAMALVLFIATALLLVFVVDELFQELRRTGHAAATARDELGRLGEAGRLKDLLLQ 147 Query: 101 ELAHRTRNDLATIMSILRLQARSDPNPAVQAAITSALARIEVVAKVHDRLRDTPVNSSVD 160 E++HRT+NDL + S+L+++ R+ +A++ +A +R+ VV +VH L+ + + V+ Sbjct: 148 EMSHRTKNDLQFLSSMLQIEGRALEEGRGRASLLAAASRMTVVGRVHSLLQHSG-SDRVE 206 Query: 161 LPAYLEALCGSLSDLHRGVRPIAIRVSCDEIAVKSSQAASVGLIVNELVTNAFKYAFPEG 220 + + LC L G+RPIA+R + A S+ LIVNELVTNA K+AFPE Sbjct: 207 MQPLFDELCADLRISLIGLRPIALRAEVTTGLLPLDAARSIALIVNELVTNALKHAFPED 266 Query: 221 RPGVVEVDVRKRNEKVVITVRDDGIGCP---TEAKSGLGTRLINLMVAQMQGGMTRAPMA 277 R G V V + + + + V DDG+G P T +G G +L+ + Q+ G +T + Sbjct: 267 RSGTVTVRLTREAGALRLLVMDDGVGHPAATTSPGTGFGQKLVRSLAQQLGGALTIEAGS 326 Query: 278 QGCEVEV 284 G E+ Sbjct: 327 AGTRCEL 333