BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0033.p (466 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_768960.1| tricarballylate dehydrogenase [Bradyrhizobium j... 835 0.0 ref|YP_002495136.1| tricarballylate dehydrogenase [Methylobacter... 744 0.0 ref|YP_004285280.1| putative precorrin 3B synthase CobZ [Acidiph... 718 0.0 ref|YP_001235832.1| tricarballylate dehydrogenase [Acidiphilium ... 718 0.0 ref|ZP_08631182.1| Tricarballylate dehydrogenase [Acidiphilium s... 714 0.0 >ref|NP_768960.1| tricarballylate dehydrogenase [Bradyrhizobium japonicum USDA 110] dbj|BAC47585.1| blr2320 [Bradyrhizobium japonicum USDA 110] Length = 474 Score = 835 bits (2157), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/463 (88%), Positives = 440/463 (95%) Query: 4 LTRRFEVLVIGGGNAALCAAISARRAGASVLVLEGAPKFYRGGNTRHTRNMRCAHDAATE 63 ++ +++VLVIGGGNAALCAAI+ARR GASVLVLEGAPKFYRGGNTRHTRNMRCAHDAATE Sbjct: 12 MSSKYDVLVIGGGNAALCAAIAARRGGASVLVLEGAPKFYRGGNTRHTRNMRCAHDAATE 71 Query: 64 ILTGPYTEEEFWNDLLLVTGGQTDEELARFMIHESKDILNWIVEQGVRWQPSLGGTLSLG 123 ILTGPYTEEEFW DLLLVTGGQTDEELAR MI ESKDILNWIVEQGVRWQPSLGGTLSLG Sbjct: 72 ILTGPYTEEEFWKDLLLVTGGQTDEELARHMIRESKDILNWIVEQGVRWQPSLGGTLSLG 131 Query: 124 RTNSFFLGGGRAMLNALYRTAEELGVDILYDAEVIDLTVEDGMFLSAQLKQPVGGKTEVR 183 RTNSFFLGGGRAMLNALY TAE LGVD+ YDAEV DL +EDGMFL+A+LK+P+ G+TE+R Sbjct: 132 RTNSFFLGGGRAMLNALYLTAERLGVDVEYDAEVTDLVIEDGMFLAARLKRPIKGETEIR 191 Query: 184 ASTLVAAAGGFEANIEWLKESWGDAADNFLIRGTPYNRGAILKMLLAKGVQEIGDPTQCH 243 A++LVAAAGGFEANIEWLK+ WG+AADNFLIRGTPYNRG+ILKMLL KGVQE+GDPTQCH Sbjct: 192 ATSLVAAAGGFEANIEWLKQYWGEAADNFLIRGTPYNRGSILKMLLDKGVQEVGDPTQCH 251 Query: 244 AVAIDARAPKFDGGIITRHDSVVFGIVVNKHAERFYDEGEDIWPKRYAIWGRLVAAQPDQ 303 AVAIDARAPKFDGGIITRHDSVVFGIVVNKHA+RFYDEGEDIWPKRYAIWGRLVAAQPDQ Sbjct: 252 AVAIDARAPKFDGGIITRHDSVVFGIVVNKHAQRFYDEGEDIWPKRYAIWGRLVAAQPDQ 311 Query: 304 IAYIIFDSTVVTSFMPTLFPPIAGATIAELAGKLELDAAALEKTITAFNAAVQPGTFDHT 363 IAYIIFDSTVVTSFMPTLFPPIAG T+AELA KLELD AALE TIT FNAAV+PGTFDHT Sbjct: 312 IAYIIFDSTVVTSFMPTLFPPIAGQTVAELASKLELDPAALETTITEFNAAVRPGTFDHT 371 Query: 364 ILDDCATQGITPPKTHWARRIETPPYLAYPVRPGITFTYLGTRVNREARMLMKDGKPSAN 423 ILDDC T+GITP KTHWARRIETPPYLAYPVRPGITFTYLGTRV +EARMLM DGKPS N Sbjct: 372 ILDDCRTEGITPQKTHWARRIETPPYLAYPVRPGITFTYLGTRVTKEARMLMADGKPSGN 431 Query: 424 MFAAGEIMAGNVLGKGYAAGIGMTIGSVFGRVAGREAARNARN 466 MFAAGEIMAGNVLGKGYAAG+GMTIGSVFGR+AGREAAR+A+N Sbjct: 432 MFAAGEIMAGNVLGKGYAAGMGMTIGSVFGRIAGREAARHAKN 474 >ref|YP_002495136.1| tricarballylate dehydrogenase [Methylobacterium nodulans ORS 2060] gb|ACL62644.1| precorrin 3B synthase CobZ [Methylobacterium nodulans ORS 2060] Length = 462 Score = 744 bits (1922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/466 (77%), Positives = 406/466 (87%), Gaps = 4/466 (0%) Query: 1 MVDLTRRFEVLVIGGGNAALCAAISARRAGASVLVLEGAPKFYRGGNTRHTRNMRCAHDA 60 M ++R++VLVIGGGNAALCAAISARR GASVLVLE A F+RGGNTRHTRNMRCAHD Sbjct: 1 MRPTSQRYDVLVIGGGNAALCAAISARREGASVLVLEAADAFWRGGNTRHTRNMRCAHDT 60 Query: 61 ATEILTGPYTEEEFWNDLLLVTGGQTDEELARFMIHESKDILNWIVEQGVRWQPSLGGTL 120 ATEILTGPYTEEEF+ DLLLVTGG+TDE+LAR MI ESK++L WI EQGVRWQPSLGGTL Sbjct: 61 ATEILTGPYTEEEFFEDLLLVTGGRTDEDLARHMIRESKEMLTWIEEQGVRWQPSLGGTL 120 Query: 121 SLGRTNSFFLGGGRAMLNALYRTAEELGVDILYDAEVIDLTVEDGMFLSAQLKQPVGGKT 180 SLGRTNSFFLGGGRAMLNALY TAE LGV++ Y+AEV DL +EDG FLSA L+ Sbjct: 121 SLGRTNSFFLGGGRAMLNALYATAERLGVEVRYEAEVTDLEIEDGHFLSATLRD----GE 176 Query: 181 EVRASTLVAAAGGFEANIEWLKESWGDAADNFLIRGTPYNRGAILKMLLAKGVQEIGDPT 240 +RA TLVAAAGGFE+NI WLK WG+AADNFLIRGT N+G ILK+LL +GVQE+GDPT Sbjct: 177 RIRAGTLVAAAGGFESNIAWLKRYWGEAADNFLIRGTSNNKGTILKLLLDRGVQEVGDPT 236 Query: 241 QCHAVAIDARAPKFDGGIITRHDSVVFGIVVNKHAERFYDEGEDIWPKRYAIWGRLVAAQ 300 QCHAVAIDARAPK+DGGIITR D VVFGIVVNKHA+RFYDEGEDIWPKRYAIWGRLVAAQ Sbjct: 237 QCHAVAIDARAPKYDGGIITRLDCVVFGIVVNKHAQRFYDEGEDIWPKRYAIWGRLVAAQ 296 Query: 301 PDQIAYIIFDSTVVTSFMPTLFPPIAGATIAELAGKLELDAAALEKTITAFNAAVQPGTF 360 PDQIAYIIFD++ + FMP+L+PPI TI ELA L LD AL +T+ FNAAV+PGTF Sbjct: 297 PDQIAYIIFDASSLELFMPSLYPPIQARTIPELALALGLDPDALARTVADFNAAVRPGTF 356 Query: 361 DHTILDDCATQGITPPKTHWARRIETPPYLAYPVRPGITFTYLGTRVNREARMLMKDGKP 420 D ILDDC T+G+TPPK+HWARRIET P+ AYPVRPGITFTYLGTRV+++ARM+M DG P Sbjct: 357 DDKILDDCRTEGLTPPKSHWARRIETAPFYAYPVRPGITFTYLGTRVDKQARMIMADGTP 416 Query: 421 SANMFAAGEIMAGNVLGKGYAAGIGMTIGSVFGRVAGREAARNARN 466 +ANMFAAGEIMAGNVLG+GYAAGIGMTIG+VFGR+AGREAAR+ARN Sbjct: 417 AANMFAAGEIMAGNVLGQGYAAGIGMTIGAVFGRIAGREAARHARN 462 >ref|YP_004285280.1| putative precorrin 3B synthase CobZ [Acidiphilium multivorum AIU301] dbj|BAJ82398.1| putative precorrin 3B synthase CobZ [Acidiphilium multivorum AIU301] Length = 468 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/458 (74%), Positives = 391/458 (85%), Gaps = 1/458 (0%) Query: 9 EVLVIGGGNAALCAAISARRAGASVLVLEGAPKFYRGGNTRHTRNMRCAHDAATEILTGP 68 + LVIGGGNAALCAAISARR GASVLVLE AP+FYRGGNTRHTRNMRCAHD+AT+ LTGP Sbjct: 12 DTLVIGGGNAALCAAISARREGASVLVLEAAPEFYRGGNTRHTRNMRCAHDSATDFLTGP 71 Query: 69 YTEEEFWNDLLLVTGGQTDEELARFMIHESKDILNWIVEQGVRWQPSLGGTLSLGRTNSF 128 YTEEEFW DLL VTGG+TDE+LARFMI ESKD+L WI QGVR+QPSLGGTLSLGRTNSF Sbjct: 72 YTEEEFWQDLLRVTGGETDEDLARFMIAESKDMLTWIARQGVRFQPSLGGTLSLGRTNSF 131 Query: 129 FLGGGRAMLNALYRTAEELGVDILYDAEVIDLTVEDGMFLSAQLKQPVGGKTEVRASTLV 188 FLGGGRAML +LYRTAE LGV ++Y+AEVI ++DG+F A ++ G V+A TLV Sbjct: 132 FLGGGRAMLKSLYRTAESLGVRVIYEAEVIGFDIQDGVFREALVRHG-GAVVPVKARTLV 190 Query: 189 AAAGGFEANIEWLKESWGDAADNFLIRGTPYNRGAILKMLLAKGVQEIGDPTQCHAVAID 248 AAAGGFEANI+WLKESWG AADNFLIRGTPYNRG IL++LL G + +GDPTQCHAVAID Sbjct: 191 AAAGGFEANIDWLKESWGAAADNFLIRGTPYNRGDILRLLLDAGAEPVGDPTQCHAVAID 250 Query: 249 ARAPKFDGGIITRHDSVVFGIVVNKHAERFYDEGEDIWPKRYAIWGRLVAAQPDQIAYII 308 ARAP+FDGGIITR D VVFG+V+N +AERFYDEGED WP+RYAIWGRLVAAQP QIAYI+ Sbjct: 251 ARAPRFDGGIITRLDCVVFGVVLNANAERFYDEGEDFWPRRYAIWGRLVAAQPGQIAYIV 310 Query: 309 FDSTVVTSFMPTLFPPIAGATIAELAGKLELDAAALEKTITAFNAAVQPGTFDHTILDDC 368 FDS + FMP+L+PP+ + LA +LELD E T+ AFN AV+ G FDHT+LDDC Sbjct: 311 FDSRSLPLFMPSLYPPVQAHDLHTLATRLELDPQRFEATLAAFNDAVREGHFDHTVLDDC 370 Query: 369 ATQGITPPKTHWARRIETPPYLAYPVRPGITFTYLGTRVNREARMLMKDGKPSANMFAAG 428 T+G++PPK+HWARRIE PP+ AYPVRPGITFTYLG RV R+AR+ M DG+P+ NMFAAG Sbjct: 371 HTEGLSPPKSHWARRIEQPPFYAYPVRPGITFTYLGVRVGRDARIRMNDGRPAVNMFAAG 430 Query: 429 EIMAGNVLGKGYAAGIGMTIGSVFGRVAGREAARNARN 466 EIMAGNVLG+GYAAGIGMTIGSVFGR+AGREAAR+ RN Sbjct: 431 EIMAGNVLGRGYAAGIGMTIGSVFGRIAGREAARHGRN 468 >ref|YP_001235832.1| tricarballylate dehydrogenase [Acidiphilium cryptum JF-5] gb|ABQ31913.1| precorrin 3B synthase CobZ [Acidiphilium cryptum JF-5] Length = 468 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/458 (74%), Positives = 391/458 (85%), Gaps = 1/458 (0%) Query: 9 EVLVIGGGNAALCAAISARRAGASVLVLEGAPKFYRGGNTRHTRNMRCAHDAATEILTGP 68 + LVIGGGNAALCAAISARR GASVLVLE AP+FYRGGNTRHTRNMRCAHD+AT+ LTGP Sbjct: 12 DTLVIGGGNAALCAAISARREGASVLVLEAAPEFYRGGNTRHTRNMRCAHDSATDFLTGP 71 Query: 69 YTEEEFWNDLLLVTGGQTDEELARFMIHESKDILNWIVEQGVRWQPSLGGTLSLGRTNSF 128 YTEEEFW DLL VTGG+TDE+LARFMI ESKD+L WI QGVR+QPSLGGTLSLGRTNSF Sbjct: 72 YTEEEFWQDLLRVTGGETDEDLARFMIAESKDMLTWIARQGVRFQPSLGGTLSLGRTNSF 131 Query: 129 FLGGGRAMLNALYRTAEELGVDILYDAEVIDLTVEDGMFLSAQLKQPVGGKTEVRASTLV 188 FLGGGRAML +LYRTAE LGV ++Y+AEVI ++DG+F A ++ G V+A TLV Sbjct: 132 FLGGGRAMLKSLYRTAESLGVRVIYEAEVIGFDIQDGVFREALVRHG-GAVVPVKARTLV 190 Query: 189 AAAGGFEANIEWLKESWGDAADNFLIRGTPYNRGAILKMLLAKGVQEIGDPTQCHAVAID 248 AAAGGFEANI+WLKESWG AADNFLIRGTPYNRG IL++LL G + +GDPTQCHAVAID Sbjct: 191 AAAGGFEANIDWLKESWGAAADNFLIRGTPYNRGDILRLLLDAGAEPVGDPTQCHAVAID 250 Query: 249 ARAPKFDGGIITRHDSVVFGIVVNKHAERFYDEGEDIWPKRYAIWGRLVAAQPDQIAYII 308 ARAP+FDGGIITR D VVFG+V+N +AERFYDEGED WP+RYAIWGRLVAAQP QIAYI+ Sbjct: 251 ARAPRFDGGIITRLDCVVFGVVLNANAERFYDEGEDFWPRRYAIWGRLVAAQPGQIAYIV 310 Query: 309 FDSTVVTSFMPTLFPPIAGATIAELAGKLELDAAALEKTITAFNAAVQPGTFDHTILDDC 368 FDS + FMP+L+PP+ + LA +LELD E T+ AFN AV+ G FDHT+LDDC Sbjct: 311 FDSRSLPLFMPSLYPPVQADDLHTLATRLELDPQRFEATLAAFNDAVREGHFDHTVLDDC 370 Query: 369 ATQGITPPKTHWARRIETPPYLAYPVRPGITFTYLGTRVNREARMLMKDGKPSANMFAAG 428 T+G++PPK+HWARRIE PP+ AYPVRPGITFTYLG RV R+AR+ M DG+P+ NMFAAG Sbjct: 371 HTEGLSPPKSHWARRIEQPPFYAYPVRPGITFTYLGVRVGRDARIRMNDGRPAVNMFAAG 430 Query: 429 EIMAGNVLGKGYAAGIGMTIGSVFGRVAGREAARNARN 466 EIMAGNVLG+GYAAGIGMTIGSVFGR+AGREAAR+ RN Sbjct: 431 EIMAGNVLGRGYAAGIGMTIGSVFGRIAGREAARHGRN 468 >ref|ZP_08631182.1| Tricarballylate dehydrogenase [Acidiphilium sp. PM] gb|EGO97029.1| Tricarballylate dehydrogenase [Acidiphilium sp. PM] Length = 468 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/458 (74%), Positives = 390/458 (85%), Gaps = 1/458 (0%) Query: 9 EVLVIGGGNAALCAAISARRAGASVLVLEGAPKFYRGGNTRHTRNMRCAHDAATEILTGP 68 + LVIGGGNAALCAAISARR GASVLVLE AP+FYRGGNTRHTRNMRCAHD+AT+ LTGP Sbjct: 12 DTLVIGGGNAALCAAISARREGASVLVLEAAPEFYRGGNTRHTRNMRCAHDSATDFLTGP 71 Query: 69 YTEEEFWNDLLLVTGGQTDEELARFMIHESKDILNWIVEQGVRWQPSLGGTLSLGRTNSF 128 YTEEEFW DLL VTGG+TDE+LARFMI ESKD+L WI QGVR+QPSLGGTLSLGRTNSF Sbjct: 72 YTEEEFWQDLLRVTGGETDEDLARFMIAESKDMLTWIARQGVRFQPSLGGTLSLGRTNSF 131 Query: 129 FLGGGRAMLNALYRTAEELGVDILYDAEVIDLTVEDGMFLSAQLKQPVGGKTEVRASTLV 188 FLGGGRAML +LYRTAE LGV ++Y+AEVI ++DG+F A ++ G V+A TLV Sbjct: 132 FLGGGRAMLKSLYRTAESLGVRVIYEAEVIGFDIQDGVFREALVRHG-GAVVPVKARTLV 190 Query: 189 AAAGGFEANIEWLKESWGDAADNFLIRGTPYNRGAILKMLLAKGVQEIGDPTQCHAVAID 248 AAAGGFEANI+WLKESWG AADNFLIRGTPYNRG IL++LL G + +GDPTQCHAVAID Sbjct: 191 AAAGGFEANIDWLKESWGAAADNFLIRGTPYNRGDILRLLLDAGAEPVGDPTQCHAVAID 250 Query: 249 ARAPKFDGGIITRHDSVVFGIVVNKHAERFYDEGEDIWPKRYAIWGRLVAAQPDQIAYII 308 ARAP+FDGGIITR D VVFG+V+N +AERFYDEGED WP+RYAIWGRLVAAQP QIAYI+ Sbjct: 251 ARAPRFDGGIITRLDCVVFGVVLNANAERFYDEGEDFWPRRYAIWGRLVAAQPGQIAYIV 310 Query: 309 FDSTVVTSFMPTLFPPIAGATIAELAGKLELDAAALEKTITAFNAAVQPGTFDHTILDDC 368 FDS + FMP+L+PP+ + LA +LELD E T+ AFN AV+ G FDHT+LDDC Sbjct: 311 FDSRSLPLFMPSLYPPVQADDLHTLATRLELDPQRFEATLAAFNDAVREGHFDHTVLDDC 370 Query: 369 ATQGITPPKTHWARRIETPPYLAYPVRPGITFTYLGTRVNREARMLMKDGKPSANMFAAG 428 T+G++PPK+HWARRIE P+ AYPVRPGITFTYLG RV R+AR+ M DG+P+ NMFAAG Sbjct: 371 HTEGLSPPKSHWARRIEQRPFYAYPVRPGITFTYLGVRVGRDARIRMNDGRPAVNMFAAG 430 Query: 429 EIMAGNVLGKGYAAGIGMTIGSVFGRVAGREAARNARN 466 EIMAGNVLG+GYAAGIGMTIGSVFGR+AGREAAR+ RN Sbjct: 431 EIMAGNVLGRGYAAGIGMTIGSVFGRIAGREAARHGRN 468