BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0257.0014.p (379 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RC0164 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 267 3e-71 BMEI0610 [O] COG0330 Membrane protease subunits, stomatin/prohib... 266 4e-71 mll1455 [O] COG0330 Membrane protease subunits, stomatin/prohibi... 266 5e-71 RP122 [O] COG0330 Membrane protease subunits, stomatin/prohibiti... 258 2e-68 SMc01441 [O] COG0330 Membrane protease subunits, stomatin/prohib... 252 1e-66 >RC0164 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Rco Rickettsia conorii Length = 346 Score = 267 bits (683), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 136/346 (39%), Positives = 210/346 (60%), Gaps = 17/346 (4%) Query: 16 KGPWGTGPQSAGPRPPDLEDLL----RRGQDRLQQWLPGGHFSGMGVALVLVAALAIWFA 71 K PW D ED + R+ Q Q+ +F+ + L +VA +A+W A Sbjct: 12 KSPWKDFD-------SDKEDNIFTRPRKNQFNFDQFQFPFNFNAKTIILAVVAVVALWLA 64 Query: 72 TGIFRVQSEELGVVLRFGKYVRDAQPGLRYHLPYPIETVLLPKALRVSTISIGMTLIDDP 131 +GI+ ++ E V+RFG++VR PGL YHLP P E +++ K + I IG Sbjct: 65 SGIYEIKEGEEAAVIRFGRFVRKGYPGLNYHLPAPFEKIIVEKVKQSRRIEIGYRTNSSL 124 Query: 132 ARRGRTMRDVPEESLMLTGDENIVDVDFTVLWRIKPGGAGAYLFNIQNPEGTVKAVAESA 191 G +++ ES+MLTGDENI+ ++ V+W I ++FN+Q P TVKA ESA Sbjct: 125 RSGGDNTKNIAGESIMLTGDENIIALNCDVMWHI--NNLEDFIFNVQRPAETVKATVESA 182 Query: 192 MREVIGRSQIQPILTGARNVTEQSVQELMQKTLDTYNAGIQITQVQMQKVDPPAQVIDAF 251 +REVIG + I +L+ + +++L QK LD+YNAG+ I +VQ+ K +PPA+VIDA+ Sbjct: 183 VREVIGNTPISWVLSDQKQEITYKIEKLAQKILDSYNAGVMIEKVQLLKAEPPAEVIDAY 242 Query: 252 RDVQAARADLERKQNEAQTYANSIVPGARGRAAQIQQAAEGYKEQAVAEAKGQSARFLKV 311 RDVQ ++AD E++ N+AQ Y N I+P ARG AA+I Q AEGY+ + +++A+G S RF + Sbjct: 243 RDVQTSKADKEKEINQAQAYNNKILPEARGAAAKIIQEAEGYRAEVISKAEGDSQRFNAI 302 Query: 312 YEEYKKAPDVTRERIYLETMEKVLGGSEKLVYDGGPGQNIVPYLPL 357 Y++Y VTR+R+YLE +E++LGGS K + + ++P++ + Sbjct: 303 YKQYATGRQVTRDRLYLEVVEEILGGSNKTIINNA----LLPHMAI 344 >BMEI0610 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Bme Brucella melitensis Length = 384 Score = 266 bits (681), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 153/357 (42%), Positives = 227/357 (63%), Gaps = 26/357 (7%) Query: 15 PKGPWGTGPQSAGPRPPDLEDLLRRGQDRLQQWLPGG---HFSGMGVALVLVAA-LAIWF 70 PKGP G G + PPDLED+LR+GQDRL+Q PGG S + ++ AA L W Sbjct: 32 PKGPRGGGQNT----PPDLEDILRKGQDRLKQVFPGGGGRKGSNRPIYFLIGAAVLGFWL 87 Query: 71 ATGIFRVQSEELGVVLRFGKYVRD-AQPGLRYHLPYPIETVLLPKALRVSTISIGMTLID 129 ++ VQ +EL V LRFGK + ++PGL +H +P ET + + I+IG Sbjct: 88 FQSVYTVQPDELAVELRFGKPKEEVSEPGLHFHW-WPFETYEKAQIVE-KQINIG----- 140 Query: 130 DPARRGRTMRDVPEESLMLTGDENIVDVDFTVLWRIKPGGAGAYLFNIQNPEGTVKAVAE 189 G+ R+ + LMLTGD+NIV+V F+VL+R+ AYLFN+ +P+ V+ V+E Sbjct: 141 -----GQGTRNATQ-GLMLTGDQNIVNVQFSVLYRV--SDPRAYLFNVDSPDAMVQQVSE 192 Query: 190 SAMREVIGRSQIQPILTGARNVTEQSVQELMQKTLDTYNAGIQITQVQMQKVDPPAQVID 249 SA+RE++GR Q + R+ QSV++++Q+TLD Y AGIQI V ++ PP +V D Sbjct: 193 SAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQTLDNYKAGIQINAVSIEDAAPPREVAD 252 Query: 250 AFRDVQAARADLERKQNEAQTYANSIVPGARGRAAQIQQAAEGYKEQAVAEAKGQSARFL 309 AF +VQ A D +R E+ Y+N + ARG AAQ+++ A YK + V +A+G++ RF Sbjct: 253 AFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDAEGEAQRFS 312 Query: 310 KVYEEYKKAPDVTRERIYLETMEKVLGGSEKLVYDGGPGQNIVPYLPLGELTPRRPA 366 V +EY+KAP+VTR R++LETME+VL G++K++ + PG+++VPYLPL EL ++P+ Sbjct: 313 SVLKEYQKAPEVTRNRLFLETMEEVLKGTKKVIVE--PGKDVVPYLPLHELMQKQPS 367 >mll1455 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Mlo Mesorhizobium loti Length = 371 Score = 266 bits (681), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 155/346 (44%), Positives = 219/346 (63%), Gaps = 24/346 (6%) Query: 14 GPKGPWGTGPQSAGPRPPDLEDLLRRGQDRLQQWLPGGHFSGMGVALVLVAAL-AIWFAT 72 GPKGP +GPQ + PPDLED++RRGQDRL++ LPGG + V ++ A L A+W Sbjct: 27 GPKGP--SGPQGS---PPDLEDIIRRGQDRLRRALPGGGGASPAVFGLIAAVLVALWAFQ 81 Query: 73 GIFRVQSEELGVVLRFGK-YVRDAQPGLRYHLPYPIETVLLPKALRVSTISIGMTLIDDP 131 ++ VQ +E+ V LRFGK +QPGL +H +P+ETV T I L+D Sbjct: 82 AVYTVQPDEVAVELRFGKPKAELSQPGLHFHW-WPLETV--------ETAKISEQLVDIG 132 Query: 132 ARRGRTMRDVPEESLMLTGDENIVDVDFTVLWRIKPGGAGAYLFNIQNPEGTVKAVAESA 191 G T + LML+GD+NIV+V F+V +++ AYLF++ +P+G ++ VAESA Sbjct: 133 G--GNTSGN----GLMLSGDQNIVNVQFSVAYQVS--DPRAYLFDVSDPDGMLRQVAESA 184 Query: 192 MREVIGRSQIQPILTGARNVTEQSVQELMQKTLDTYNAGIQITQVQMQKVDPPAQVIDAF 251 MRE +GR Q I R SV+E++Q TLD Y AG+ + V ++ PP +V DAF Sbjct: 185 MREAVGRRPAQDIFRDDRQGIAASVREIIQSTLDGYKAGLNVNAVSIEDAAPPREVADAF 244 Query: 252 RDVQAARADLERKQNEAQTYANSIVPGARGRAAQIQQAAEGYKEQAVAEAKGQSARFLKV 311 +VQ A D ++ +A Y+N + ARG+AAQI++ A YK + V EA+G++ RF+ V Sbjct: 245 DEVQRAEQDEDKFVEQANQYSNQKLGQARGQAAQIREDAAAYKNRVVQEAEGEAQRFISV 304 Query: 312 YEEYKKAPDVTRERIYLETMEKVLGGSEKLVYDGGPGQNIVPYLPL 357 Y+EY KAPDVTR+R+YLETME+VL S K++ + G GQ +VPYLPL Sbjct: 305 YDEYAKAPDVTRKRLYLETMERVLKDSSKVIVEQGNGQGVVPYLPL 350 >RP122 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Rpr Rickettsia prowazekii Length = 344 Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 128/317 (40%), Positives = 203/317 (64%), Gaps = 11/317 (3%) Query: 42 DRLQQWLPGGHFSGMGVALVLVAALAIWFATGIFRVQSEELGVVLRFGKYVRDAQPGLRY 101 D+LQ P +F+ + L + A + +W +GI+ ++ E V+RFG++VR PGL Y Sbjct: 38 DKLQ--FPF-NFNTKTIILAVGAMVILWLVSGIYEIKEGEEAAVIRFGRFVRKGYPGLNY 94 Query: 102 HLPYPIETVLLPKALRVSTISIGMTLIDDPARRGRTMRDVPEESLMLTGDENIVDVDFTV 161 H P P E +++ K + I IG + + R +++ ES+MLTGDENIV ++ V Sbjct: 95 HFPSPFENIIVEKVKQSRRIEIGYRT--NSSMRSGGDKNIVSESIMLTGDENIVSLNCDV 152 Query: 162 LWRIKPGGAGAYLFNIQNPEGTVKAVAESAMREVIGRSQIQPILTGARNVTEQSVQELMQ 221 +W I ++FN+Q PE TVKA ES++REVIG + I +L+ + +++L Q Sbjct: 153 MWHI--SNLEDFIFNVQRPEETVKATVESSIREVIGNTPISWVLSDQKQEITYKIEKLAQ 210 Query: 222 KTLDTYNAGIQITQVQMQKVDPPAQVIDAFRDVQAARADLERKQNEAQTYANSIVPGARG 281 K LD+YNAG+ I +VQ+ K +PP++VIDA+RDVQ ++AD E++ N+AQ Y N I+P ARG Sbjct: 211 KILDSYNAGVMIEKVQLLKAEPPSEVIDAYRDVQTSKADKEKEINQAQAYNNKILPEARG 270 Query: 282 RAAQIQQAAEGYKEQAVAEAKGQSARFLKVYEEYKKAPDVTRERIYLETMEKVLGGSEKL 341 AA+I Q AEGY+E+ +++A+G S RF +Y++Y VTR+R+YLE +E++LGGS K Sbjct: 271 TAAKIIQEAEGYREEVISKAEGDSQRFNAIYKQYATGRQVTRDRLYLEVVEEILGGSNKT 330 Query: 342 VYDGGPGQNIVPYLPLG 358 + + ++P++ + Sbjct: 331 IINNA----LLPHMLIN 343 >SMc01441 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Sme Sinorhizobium meliloti Length = 362 Score = 252 bits (643), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 143/330 (43%), Positives = 207/330 (62%), Gaps = 18/330 (5%) Query: 32 DLEDLLRRGQDRLQQWLPGGHFSGMGVALVLVAALAIWFATGIFRVQSEELGVVLRFGKY 91 DLE+++RRGQD+L+ +PGG F+G +V + L I+ VQ +E GV +RFGK Sbjct: 40 DLEEIIRRGQDQLKNVVPGG-FNGGIFVIVGLLILGFVLLNSIYTVQPDERGVEMRFGKP 98 Query: 92 VRD-AQPGLRYHLPYPIETVLLPKALRVSTISIGMTLIDDPARRGRTMRDVPEESLMLTG 150 + + PGL YH +P+ETV + K +IG GRT + LML+G Sbjct: 99 KEEISMPGLHYHF-WPLETVEIVKVTEQQQ-NIG----------GRTGQ--SNAGLMLSG 144 Query: 151 DENIVDVDFTVLWRIKPGGAGAYLFNIQNPEGTVKAVAESAMREVIGRSQIQPILTGARN 210 D+NIV+V F+VL+ + AYLFN++NP T++ VAESAMREV+GR Q I R Sbjct: 145 DQNIVNVQFSVLFSVTD--PKAYLFNVENPADTLQQVAESAMREVVGRRPAQDIFRDNRQ 202 Query: 211 VTEQSVQELMQKTLDTYNAGIQITQVQMQKVDPPAQVIDAFRDVQAARADLERKQNEAQT 270 V+ +Q T+D+Y AGI + V ++ PP +V DAF +VQ A D +R EA Sbjct: 203 AIAADVKNTIQATMDSYGAGISVNTVAIEDAAPPREVADAFDEVQRAEQDEDRFVEEANQ 262 Query: 271 YANSIVPGARGRAAQIQQAAEGYKEQAVAEAKGQSARFLKVYEEYKKAPDVTRERIYLET 330 YAN ++ ARG+ AQI++ A YK++ V EA+G++ RF+ VY+EY KAP+VTR+R+Y+ET Sbjct: 263 YANQVLGRARGQGAQIREEAAAYKDRVVKEAQGEAQRFISVYDEYSKAPEVTRKRLYIET 322 Query: 331 MEKVLGGSEKLVYDGGPGQNIVPYLPLGEL 360 ++ VLG S+K++ D GQ ++PYLPL E+ Sbjct: 323 LQGVLGKSKKVILDEKNGQGVLPYLPLNEI 352