BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0257.0004.p         (166 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA0148 [QR] COG0500 SAM-dependent methyltransferases Mac Methano...    97   2e-20

>MA0148 [QR] COG0500 SAM-dependent methyltransferases Mac Methanosarcina
           acetivorans str.C2A
          Length = 233

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 56/158 (35%), Positives = 83/158 (52%), Gaps = 3/158 (1%)

Query: 4   EVDAIDISPAMIGLAEIYARDR-KAKIRTQPAGLLSFAYQPNSYDLIVSEFTLHHLPDFW 62
           +V AID+S  MI  A   A  + K  I+   AG L++      +D+IV++  LHHLPD+W
Sbjct: 77  QVIAIDVSKMMINFARRKAESQNKTNIQFYNAGFLTYENHDELFDVIVTQLALHHLPDYW 136

Query: 63  KAVALSRIFNALKPGANFYLRDMVFVGMPDGVDRDVEG-WADFSIKNHGFERESVITHMR 121
           K +AL RI+  LK    FYL D+VF       D   +    D  I       E    H++
Sbjct: 137 KMMALRRIYGMLKEEGKFYLHDVVFPSSIQNYDSYFDKIITDLEISAGDKIAEETEIHIK 196

Query: 122 DEYSTFGWVMERMLTETGFTLDSVDYHAPLHGTYLLRK 159
           +E+ST  WVME +LT  GF ++ + Y   +  +Y+ +K
Sbjct: 197 EEFSTLDWVMEGLLTGVGFYIEYIKYDGFM-ASYICKK 233