BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0255.0009.p (1163 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VCA0638 [V] COG0841 Cation/multidrug efflux pump Vch Vibrio chol... 692 0.0 aq_695 [V] COG0841 Cation/multidrug efflux pump Aae Aquifex aeol... 656 0.0 SMa0875 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobi... 259 3e-68 AGl494 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteriu... 258 4e-68 RSc3205 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 217 2e-55 >VCA0638 [V] COG0841 Cation/multidrug efflux pump Vch Vibrio cholerae Length = 1067 Score = 692 bits (1785), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/1004 (41%), Positives = 596/1004 (59%), Gaps = 32/1004 (3%) Query: 2 KLGLSGRLTRVTLTSPLTSLFLLASLAVGLIAVMVIPREEEPQISVPMVDIRVNADGLRG 61 +LG+SGR+ S +T L L L +GL AVMV P+EEEPQI V D+ + G Sbjct: 19 RLGISGRIAAAFQNSAMTPLLALVGLLMGLFAVMVTPKEEEPQIDVTFADVYIPFPGASP 78 Query: 62 PDAVELVSKPLEAIVKAIDGVEHVYSQTEDDRVMVTARFLVGTKFEDAILRVHEKVRANL 121 + LV+ P E ++ I+G++ +YS ++ D M+ A F VG DA++R++ K+ +N Sbjct: 79 REVESLVTTPAEQVISEIEGIDKIYSFSQPDGAMIVAIFKVGVPRNDAVVRIYNKLYSNK 138 Query: 122 DHIP--VGIPEPLIVGRGINDVAVTVLTLSPKPEAAERWSDKDLFELADKLRSELIKVDN 179 D +P VG+ EP+I +GI DV + +TL+ K ++R+ + L ++A L +EL ++ Sbjct: 139 DWMPQGVGVGEPIIKPKGIEDVPIVTITLADK---SDRFDQQQLTQVAHGLETELKRIPG 195 Query: 180 VGLTYVSGGSAQQIRVEPDPEKLSLFGVTLQQLVAKVKEANRSFVAGQVRDAGLVRNVAA 239 Y GG + V DP K++ FG+TL QL + AN+S ++ V Sbjct: 196 TRDIYTIGGQNTIVDVRLDPAKMNGFGITLDQLNQSLPAANQSSPMLRLTHDNQEFPVQV 255 Query: 240 GQTLTGIPDIGLLLIATRDGRPIYVKDVASVAIGPNTVEHRVWNDARDAAGQWRRAPAVS 299 GQ LT + ++ L++ +G P+Y++D+A+V+ G NT VW RD PAV+ Sbjct: 256 GQFLTRVEEVKQLVVGLHNGTPVYLEDIATVSFGVNTATQNVWTGDRDGI-----HPAVT 310 Query: 300 LALAKRAGANAVVVSADIAPRLDELKAHLVPDDIQITVTRDYGETANEKANELLFHLALA 359 +A+AK+ G NAV V+ + RL L+ L+P I + +TRDYG+TA +K+N L+ LA A Sbjct: 311 IAVAKKGGENAVDVAKAVEARLVSLENQLIPQGIDVDITRDYGQTAADKSNTLMGKLAFA 370 Query: 360 TVSIVVLIAIAIGWREAVVTLVVIPTTILLTLFAANLMGYTINRVSLFALIFSIGILVDD 419 T ++V+L+ + +GWRE++V + I T+++TLFA+ G+T+NRVSLFALIFSIGILVDD Sbjct: 371 TTAVVILVLLTMGWRESIVVGMAIIVTLMITLFASWAWGFTLNRVSLFALIFSIGILVDD 430 Query: 420 AIVIVENIARHWAMHDGRSRLQATV-EAVAEVGNPTIIATLTVVAALLPMLFVSGLMGPY 478 AIV+VENI RH AM G+ +L + AV EVG PTI+ATLTV+AALLPM FVSGLMGPY Sbjct: 431 AIVVVENIHRHMAM--GKRKLSELIPPAVDEVGGPTILATLTVIAALLPMAFVSGLMGPY 488 Query: 479 MAPIPANASAAMLFSFFVAVVIAPWLMLKLAPRDDAAGEHVLHREGPLGR-LYRRFATPV 537 M+PIP NAS ML S VA V++PWL K AG H EG ++ + +P Sbjct: 489 MSPIPINASMGMLISLAVAFVLSPWLAGKFL----KAGHH--QEEGKAANGIFHKIMSPF 542 Query: 538 V---RSKRAAWIFLLGVGVATLLSMALFATKSVTVKLLPFDNKSEIAVMVDLPEGASLEA 594 V + R LL + S+ L ++V +K+LPFDNKSE +++D+PEG+SLE Sbjct: 543 VTAPKQGRNRLFLLLTILALIAGSVLLPVFQAVVLKMLPFDNKSEFQIVLDMPEGSSLEK 602 Query: 595 TERTLFAASEIARQLPETTSLQSYAGTAAPFNFNGLVRHYYLREKPELGELQVNLTARGD 654 T+R LF +PE Q YAGTAAP NFNGLVRHY++R + G++QVNL R + Sbjct: 603 TQRVLFEMGATLNDVPEVRDYQIYAGTAAPINFNGLVRHYFMRNQAHQGDIQVNLLGRKE 662 Query: 655 RKRASHDIALELRQRLKALDVPNGTSVKVVEVPPGPPVLATLLAEIYGPDAATRRAVTAE 714 R R SH IA +LR +L + G VKVVEVPPGPPV + +LAE+YGP R + Sbjct: 663 RDRDSHTIASQLRPQLNEIAQRFGGKVKVVEVPPGPPVWSPILAEVYGPTQEIRNEAARK 722 Query: 715 LKKIFADVPFIVDIDDSIGEKRPRLRLSIDQDRLEFFAVEQRDVYDTIQALFGGISIGYS 774 +++IF + IVD+D + E+ + ++ ID+ + V + D + GG I Y Sbjct: 723 VREIFRETKDIVDVDMYLPERHEKWQVVIDRSKAAHLQVPYASIVDALATAVGGKPITYL 782 Query: 775 HRGEGRNPIEIAVRLPKRGLAWDEALASTPVPANTLPGSKTVVELGQVVKATVEQGTPVI 834 H + PI I ++ + E + + V + P L +V+ + I Sbjct: 783 HSEHSKYPIPIQIQATETAKVRLEQVLNMKVGS---PNGHA-YPLSDLVEVRQTRMDDYI 838 Query: 835 FRRDGRFADMVMAELAGRFEAPLYGMMEVASRVAAHDWGDLPKPAISLHGQPTDESRPTL 894 ++ MV+ +++G ++PLYGM E+ A + L + I QP S + Sbjct: 839 VHKNLVPMVMVVGDMSGELDSPLYGMFEIG--FALDEQMGLAQYYIH---QPDGLSGVAV 893 Query: 895 LWDGEWEITYVTFRDMGAAFGAAILGIYVLVVAQFGSFRLPLVILTPIPLTLIGILIGHW 954 WDGEW +TY TFRDMG A+ ++ IY+LVVAQF S+ +PL+I+ PIPLT+IG++ GH Sbjct: 894 AWDGEWTVTYETFRDMGIAYAVGMVLIYLLVVAQFKSYLVPLIIMAPIPLTIIGVMPGHA 953 Query: 955 LLGAPFTATSMIGFIALAGIIVRNSILLVDFIRHSGGHGASLRE 998 LLGA FTATSMIG IALAGIIVRNSILLVDFI G + E Sbjct: 954 LLGAQFTATSMIGMIALAGIIVRNSILLVDFINQQVEQGMAFSE 997 >aq_695 [V] COG0841 Cation/multidrug efflux pump Aae Aquifex aeolicus Length = 1082 Score = 656 bits (1693), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/999 (40%), Positives = 600/999 (60%), Gaps = 34/999 (3%) Query: 4 GLSGRLTRVTLTSPLTSLFLLASLAVGLIAVMVIPREEEPQISVPMVDIRVNADGLRGPD 63 GL+GRL + S LT + +L SLA+GL AV+ PREEEPQI VPM+DI + G P+ Sbjct: 3 GLAGRLANFFIDSKLTPILILVSLALGLFAVLTTPREEEPQIVVPMIDIFIPYPG-ATPE 61 Query: 64 AVEL-VSKPLEAIVKAIDGVEHVYSQTEDDRVMVTARFLVGTKFEDAILRVHEKVRANLD 122 VE V PLE I+ + +E++YS + +D +VTARF VGT A++ ++ K+ + LD Sbjct: 62 EVEARVVFPLEKILWELKDIEYIYSASTNDMGIVTARFYVGTDPVKALVDLNSKMMSALD 121 Query: 123 HIPVGIPEPLIVG-RGINDVAVTVLTLSPKPEAAERWSDKDLFELADKLRSELIKVDNVG 181 P G+ P +V I+DV + LTL E + +L LA L++E+ K++NV Sbjct: 122 KAPPGVILPPVVRLMSIDDVPILTLTLW-----GENYDWYELRRLAATLQNEIKKIENVA 176 Query: 182 LTYVSGGSAQQIRVEPDPEKLSLFGVTLQQLVAKVKEANRSFVAGQVRDAGLVRNVAAGQ 241 Y+ GG +QIR+ DP K++ +G++ + ++ AN ++G++ + V G Sbjct: 177 NVYLIGGRPRQIRIILDPAKMAAYGISPLYIDQLLRSANAQAISGKINKGNMEYLVKTGP 236 Query: 242 TLTGIPDIGLLLIATRDGRPIYVKDVASVAIGPNTVEHRVW---NDARDAAGQWRR---- 294 + D+ +++ R+GR I++KDVA + GP+ ++ V+ +A + G + Sbjct: 237 FFKSVRDVENVVVGVRNGRVIFLKDVAKIVDGPSEIKDYVFFGIGEAHEYKGIEGKPGEL 296 Query: 295 APAVSLALAKRAGANAVVVSADIAPRLDELKAHLVPDDIQITVTRDYGETANEKANELLF 354 PAV++A+AKR G NAVVV+ + ++ LK ++P D+ ITVTR+YGETA EKA ELL Sbjct: 297 YPAVTIAVAKRKGTNAVVVAEQVIEFVESLKGKVIPSDVNITVTRNYGETAQEKALELLE 356 Query: 355 HLALATVSIVVLIAIAIGWREAVVTLVVIPTTILLTLFAANLMGYTINRVSLFALIFSIG 414 HL +AT S+V+LIA+++G REA+V + +P T+ + LF + G+T+NRV+LFALIFSIG Sbjct: 357 HLFIATFSVVLLIAVSLGVREAIVVGLAVPVTLSIALFLNEMYGFTLNRVTLFALIFSIG 416 Query: 415 ILVDDAIVIVENIARHWAMHDGRSRLQATVEAVAEVGNPTIIATLTVVAALLPMLFVSGL 474 ILVDDAIV+VENI R + M R A V A EVGNPTI+AT TV+AAL+PM FV+G+ Sbjct: 417 ILVDDAIVVVENIHRWFEMQKLPPR-DAIVHATDEVGNPTILATFTVIAALMPMAFVTGM 475 Query: 475 MGPYMAPIPANASAAMLFSFFVAVVIAPWLMLKLAPRDDAAGEHVLHREGPLGRLYRRFA 534 MGPYM PIP NAS AM FS VA ++ PW + + + E + R+ +LY Sbjct: 476 MGPYMRPIPINASVAMFFSLLVAFIVTPWAAYHIL-KKEREHEEINIRKTLFWKLYCHIM 534 Query: 535 TPVVRSKRAAWIFLLGVGVATLLSMALFATKSVTVKLLPFDNKSEIAVMVDLPEGASLEA 594 P++ SK + F L V S+ L TK+V VK+LP+DNKSE+ +++D+PEG +LE Sbjct: 535 YPLLASKLKRYAFYLFVLALMGGSVGLLFTKTVLVKMLPYDNKSELEIVLDMPEGTTLED 594 Query: 595 TERTLFAASEIARQLPETTSLQSYAGTAAPFNFNGLVRHYYLREKPELGELQVNLTARGD 654 T + ++ + T Q YAGTAAPF FNGLVRHYYLR+ L E+QVNL + D Sbjct: 595 TLKVAKEIADYVGRYSIVTDYQIYAGTAAPFTFNGLVRHYYLRQASNLAEIQVNLVGKHD 654 Query: 655 RKRASHDIALELRQRLKALDVPNGTSV-KVVEVPPGPPVLATLLAEIYGPDAATRRAVTA 713 R SH+ A +R ++ + G VVEVPPGPPVL+ ++AE+Y PD +R Sbjct: 655 RDLQSHEFAKLIRPKVHEIASKYGAKYVAVVEVPPGPPVLSPIVAEVYAPDMKVQREFAW 714 Query: 714 ELKKIFADVPFIVDIDDSIGEKRPRLRLSIDQDRLEFFAVEQRDVYDTIQALFGGISIGY 773 + KIF D P I D + P +R + +D+++ + +++V T++AL GG G Sbjct: 715 RVLKIFKDSPAITDEGIYLEYPAPMIRFEVKEDKVKLAGLTKQEVVYTLKALIGGWQAGI 774 Query: 774 SHRGEGRNPIEIAVRLPKRGLAWDEALASTPVPANTLPGSKTVVELGQVVKATVEQGTPV 833 + + + I +RL ++ E L + +P ++ L ++V+ Sbjct: 775 MQTTDTEH-VPIIIRLDEKYRV-PELLKNVKIPNR----EGKLIPLSELVEIKEGPIPET 828 Query: 834 IFRRDGRFADMVMAELAGRFEAPLYGMMEVASRV--AAHDWGDLPKPAISLHGQPTDESR 891 I+ ++ R V+ ++AGR EAP+YG+++V ++ + +G++ + +SL P E R Sbjct: 829 IYHKNLRRVIYVIGDVAGREEAPIYGILDVRDKILNIENPYGEVGELWMSL---PVLEDR 885 Query: 892 PTLLWDGEWEITYVTFRDMGAAFGAAILGIYVLVVAQFGSFRLPLVILTPIPLTLIGILI 951 + WDGE IT FRD+G AF A+ +YVLV+ F FR+P +IL PIPLTL+GI+ Sbjct: 886 VYVKWDGEMHITLEVFRDLGLAFAVAVFVMYVLVLGWFKDFRIPGIILAPIPLTLVGIIP 945 Query: 952 GHWLL-----GAPFTATSMIGFIALAGIIVRNSILLVDF 985 GHWL+ FTATSMIGFIAL GIIVRNSILLVDF Sbjct: 946 GHWLMDKIMGNVFFTATSMIGFIALGGIIVRNSILLVDF 984 >SMa0875 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1065 Score = 259 bits (661), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 256/1018 (25%), Positives = 458/1018 (44%), Gaps = 97/1018 (9%) Query: 9 LTRVTLTSP-LTSLFLLASLAVGLIAVMVIPREEEPQISVPMVDIRVNADGLRGPDAVEL 67 LTR+++ P ++ ++ L +GL + + + P+ +P+V + G P++VE Sbjct: 3 LTRISINHPVFATMMMVMILVLGLFSYGRLGVDHYPETDLPVVVVATTYTG-ASPESVES 61 Query: 68 -VSKPLEAIVKAIDGVEHVYSQTEDDRVMVTARFLVGTKFEDAILRVHEKVRANLDHIPV 126 +S+P+EA + I G++ + S++ + R +V +F V +DA V ++V P Sbjct: 62 EISRPIEAALNTIGGIDTITSESYEGRSIVVVQFEVDVDSQDAAQEVRDRVARLETKFPD 121 Query: 127 GIPEPLIV-----GRGINDVAVTVLTLSPKPEAAERWSDKDLFELADK-LRSELIKVDNV 180 G+ P + G+ I VAV+ T PE + LA + + + L + V Sbjct: 122 GVATPQVTRYKPEGQAILSVAVSS-TSRTLPE---------ITTLATRVINNRLSVISGV 171 Query: 181 GLTYVSGGSAQQIRVEPDPEKLSLFGVTLQQLVAKVKEANRSFVAGQVRDAGLVRNVAAG 240 G + G S +Q+ V DP++L +G+ + ++ ++ N+ AG + R V Sbjct: 172 GQVSLIGSSERQVLVVVDPDRLGAYGLAVSTVIEAIRGENQDRAAGTLISGINQRIVTVE 231 Query: 241 QTLTGIPDIGLLLIATRDGRPIYVKDVASVAIGPNTVEHRVWNDARDAAGQWRRAPAVSL 300 + +++A R+G P+Y+ +VA++ V + ++ + L Sbjct: 232 GRIANTSGFNRIIVAQRNGYPVYLSEVATILDTGAEVT---------SLANYQGQTTLGL 282 Query: 301 ALAKRAGANAVVVSADIAPRLDELKAHLVPDDIQITVTRDYGETANEKANELLFHLALAT 360 + K GAN V V++ + + L A L D++Q+T+TRD + +++ L Sbjct: 283 HIVKVQGANTVEVASAVRREVSALNAELTKDNVQLTITRDNSRPIASQVSQVQRTLVEGG 342 Query: 361 VSIVVLIAIAIG-WREAVVTLVVIPTTILLTLFAANLMGYTINRVSLFALIFSIGILVDD 419 V V+++ I + WR V+T + +P +++ T A +G+T+N ++L AL SIGIL+DD Sbjct: 343 VLSVLIVFIFLNSWRSTVITGLTLPISVIGTFAAIYALGFTLNIMTLMALSLSIGILIDD 402 Query: 420 AIVIVENIARHWAMHDGRSRLQATVEAVAEVGNPTIIATLTVVAALLPMLFVSGLMGPYM 479 AIV+ ENI RH M G+ ++A ++ E+G + TL +VA LP+ F+ GL+G + Sbjct: 403 AIVVRENITRHLQM--GKDPVRAALDGTNEIGLAVLSTTLCIVAVFLPVAFMGGLIGRFF 460 Query: 480 APIPANASAAMLFSFFVAVVIAPWLM-LKLAPRDDAAGEHVLHREGPLGRLYRRFAT--- 535 + A++ S FV+ + P L + P+ + G G+L RF Sbjct: 461 LQFGVTVAVAVVISLFVSFTLDPMLSSVWCDPQSQKTA-----KRGFFGQLIERFDQWFE 515 Query: 536 PVVRSKRAAWIFLLG---VGVATLLSM---ALFATKSVTVKLLPFDNKSEIAVMVDLPEG 589 + R+ F +A +L M +L + + LP ++ E+++ ++ EG Sbjct: 516 GLASRYRSVIYFTFDYRKTTIAIVLGMFVVSLLLVPRIGTEFLPPPDQGEVSISLEANEG 575 Query: 590 ASLEATERTLFAASEIARQLPETTSLQSYAGTAAPFNFNGLVRHYYLREKPELGELQVNL 649 ASL+ + +I R L E + S T G + + V L Sbjct: 576 ASLDYMAAKV---GQIERALREFNYVSSTYSTINSGEMRGFNKAL----------VAVQL 622 Query: 650 TARGDRKRASHDIALELRQRLK---ALDVPNGTSVKVV-EVPPGPPVLATLLAEIYGPDA 705 R+ + + +R+RL L++ G +VV + P L I G Sbjct: 623 VHSSQRRLKTAETLGPIRRRLSRIAGLEISVGQRSEVVGSIKP-------LQLSILGDGD 675 Query: 706 ATRRAVTAELKKIFADVPFIVDIDDSIGEKRPRLRLSIDQDRLEFFAVEQRDVYDTIQAL 765 R ++ + + A +P +I+ SI + RP L + + ++ V + DT+++L Sbjct: 676 EELRRISDHITSVLAAIPGATEIESSIEKLRPTLAVRVRREAASDLGVSIATIGDTLRSL 735 Query: 766 FGG--ISIGYSHRGEGRNPIEIAVRLPKRGLAWDEALASTPVPANTLP--GSKTVVELGQ 821 G IS+ S GE ++ VRLP G L + P+ + G +V L Q Sbjct: 736 VAGDAISVWNSPDGETH---DVVVRLPAAGRENAAQLRNLPIATARMDDNGKPIMVLLDQ 792 Query: 822 VVKATVEQGTPVIFRRDGRFADMVMAELAGRFEAPLYGMMEVASRVAAHDWGDLPKPA-I 880 V I R+D + + + GR + VA AA D+P I Sbjct: 793 VADVVESTAPAQITRKDLSRDIRISSNIEGRTLGDV-----VADLKAAMTKMDIPVGFRI 847 Query: 881 SLHGQPTDESRPTLLWDGEWEITYVTFRDMGAAFGAAILGIYVLVVAQFGSFRLPLVILT 940 S G + + T Y + A++ IY+++ +QFGSF P+ I+ Sbjct: 848 SFGGDAENLTEST---------AYAL-----QSLAMAVIFIYIILASQFGSFIQPIAIIM 893 Query: 941 PIPLTLIGILIGHWLLGAPFTATSMIGFIALAGIIVRNSILLVDFIRHSGGHGASLRE 998 +PL+L+G+L+G G+ SMIG + L G++ +N+ILLVD+ G SLR+ Sbjct: 894 TMPLSLMGVLLGLLFTGSTLNMFSMIGIMMLMGLVTKNAILLVDYSNLGVREGKSLRQ 951 >AGl494 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1048 Score = 258 bits (660), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 295/1029 (28%), Positives = 480/1029 (46%), Gaps = 102/1029 (9%) Query: 9 LTRVTLTSP-LTSLFLLASLAVGLIAVMVIPREEEPQISVPMVDIRVNADGLRGPDAVEL 67 LTR+++ P ++ ++A L +G ++ + ++ P + VP+V + + G P+ VE+ Sbjct: 3 LTRISVNHPVFATMMMVALLVMGAFSLQRLGLDQYPNVDVPVVVVVTSYPGAT-PETVEM 61 Query: 68 -VSKPLEAIVKAIDGVEHVYSQTEDDRVMVTARFLVGTKFEDAILRVHEKVRANLDHIPV 126 V++P+E + AI G++ V S + + R +V A+F + + A V +K+ A + P Sbjct: 62 EVTRPVEDALNAIGGLDEVTSTSYEGRSVVVAKFKLEVQSSAAAQEVRDKIAAIEANFPE 121 Query: 127 GIPEPLIVGRGINDVAVTVLTLSPKPEAAERWSDKDLFELADKLRSELIKVDNVGLTYVS 186 +P+I + A +L+L+ + + + L E K+ +L V +G + Sbjct: 122 DTKKPVI--SRFDPAAEPILSLAISSTSLDVPALATLAE--QKVVRQLTTVAGIGQATLV 177 Query: 187 GGSAQQIRVEPDPEKLSLFGVTLQQLVAKVKEANRSFVAGQVRDAGLVRNVAAGQTLTGI 246 GG +QI V D ++ G+ + ++V ++ N + AG V D R + Q+ Sbjct: 178 GGRKRQIDVTIDETRMRALGIGVNEVVTALRAGNSNSPAGSVVDPVSERTIQI-QSRIEE 236 Query: 247 PDIGL-LLIATRDGRPIYVKDVASVAIGPNTVEHR-VWNDARDAAGQWRRAPAVSLALAK 304 P+ L +++A R G I ++DVA+++ G E+R ++N GQ A+++ + K Sbjct: 237 PEALLDMVVARRGGVAILLRDVATLSEGAADAENRAIYN------GQ----TALAIDIVK 286 Query: 305 RAGANAVVVSADIAPRLDELKAHLVPDDIQITVTRDYG----ETANEKANELLFHLALAT 360 AN V V +D+ RLD L A L P +IQ+ + D E+ + L+ ALA Sbjct: 287 VQDANTVQVVSDVRKRLDALNAELSPQNIQLRIVTDSSIPIQESVTQVQTTLIEGAALA- 345 Query: 361 VSIVVLIAIAIGWREAVVTLVVIPTTILLTLFAANLMGYTINRVSLFALIFSIGILVDDA 420 V+IV L + WR V+T + +P I+ TL + +G+T+N +SL AL SIGILVDDA Sbjct: 346 VAIVFLFLNS--WRSTVITGLTLPIAIIGTLTVVDFLGFTLNTLSLLALTLSIGILVDDA 403 Query: 421 IVIVENIARHWAMHDGRSRLQATVEAVAEVGNPTIIATLTVVAALLPMLFVSGLMGPYMA 480 IV+ ENI RH +H G+S L+A ++ E+G I T T+VA LP+ F+ G++G + Sbjct: 404 IVVRENITRH--LHMGKSHLRAALDGTGEIGLAVIATTATIVAVFLPVAFMDGIVGRFFY 461 Query: 481 PIPANASAAMLFSFFVAVVIAPWLMLKLAPRD-DAAGEHVLHREGPLGRLYRRFATP--- 536 SAA+L S FVA + P ML D DA + + GP+GRL RF Sbjct: 462 QFGVTVSAAVLISLFVAFTLDP--MLSSVWYDPDAQADA---KRGPIGRLIARFDHGFEW 516 Query: 537 VVRSKRAAWIFLLGVGVATLLSMA------LFATKSVTVKLLPFDNKSEIAVMVDLPEGA 590 + R A + L + TLL A LF V + +P ++ + + P G+ Sbjct: 517 MAGQYRHAIDWTLRHRLVTLLVTAGIFIGSLFMVPLVGTEFVPDADEGRFQINLTAPVGS 576 Query: 591 SLEATERTLFAASEIARQLPETTSLQSYAGTAAPFNFNGLVRHYYLREKPELGELQVNLT 650 SL+ T L + R+ PE L S T +H + V L Sbjct: 577 SLDYTTAKLQQVKKALREFPEVEMLYSTINTGGAAG-----KHR--------AAILVGLV 623 Query: 651 ARGDRKRASHDIALELRQRLKALDVPNGTSVKVVEVPPG---PPVLATLLAEIYGPDAAT 707 R++ +A +R+RL A+ G + +++ G PV ++L G D A Sbjct: 624 PLSAREQTPLSLAEPVRKRLSAIP---GIEINILQNGLGGGESPVQLSIL----GDDRAV 676 Query: 708 RRAVTAELKKIFADVPFIVDIDDSIGEKRPRLRLSIDQDRLEFFAVEQRDVYDTIQALFG 767 + L + +P +V++ S + L + + + + D+ + AL G Sbjct: 677 LEKIANGLVEDMKKIPGLVEVTSSTKDVTSILSVRLKPAAASDLGIARADLAAALSALIG 736 Query: 768 GISIGYSHRGEGRNPIEIAVRLP--KRGLA--WDEALASTP-VPANTLPGSKTVVELGQV 822 G + G N +I VRLP +R A E + +T AN G+ +V L QV Sbjct: 737 GEDVSKWTDAHG-NSYDIVVRLPVERRSDAARLGELMITTGRTGAN---GAPLMVRLDQV 792 Query: 823 VKATVEQGTPVIFRRDGRFADMVMAELAGRFEAPLYGMMEVASRVAAHDWGDLPKPAISL 882 I R D R +V A + GR GD+ + +L Sbjct: 793 ADIGTVAAPAEIRRFDNRREILVSANITGR------------------TLGDVTE---TL 831 Query: 883 HGQPTDESRPT---LLWDGEWEITYVTFRDMGAAFGAAILGIYVLVVAQFGSFRLPLVIL 939 G P + + GE E T MG A AI+ IY+++ +QFGSF PL I+ Sbjct: 832 QGLTASRDLPAGYRIRFGGEAETMQETVGHMGTALSMAIIFIYIVLASQFGSFLQPLAIM 891 Query: 940 TPIPLTLIGILIGHWLLGAPFTATSMIGFIALAGIIVRNSILLVDFIRHSGGHGASLREV 999 +PL+LIG+L+G + G+ S+IGFI L G++ +N ILLVDF G +L E Sbjct: 892 VSLPLSLIGVLLGLMVAGSTINMFSLIGFIMLMGLVTKNGILLVDFANRERRRGLTLNEA 951 Query: 1000 CSRP--VRF 1006 + +RF Sbjct: 952 LANAGVIRF 960 >RSc3205 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1040 Score = 217 bits (552), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 240/991 (24%), Positives = 425/991 (42%), Gaps = 81/991 (8%) Query: 20 SLFLLASLAV-GLIAVMVIPREEEPQISVPMVDIRVNADGLRGPDAVELVSKPLEAIVKA 78 +LFL+ +++ GLI+ + R E+P +V ++ I G + + V++ +E ++ Sbjct: 19 TLFLICLISLAGLISFFKLGRAEDPAFTVKVMTIITAWPGATAQEMQDQVAEKIEKRIQE 78 Query: 79 IDGVEHVYSQTEDDRVMVTARFLVGT---KFEDAILRVHEKVRANLDHIPVGIPEPLIVG 135 + + + T T L T + ++ + +KV + ++P G+ P+ V Sbjct: 79 LRWYDRTETYTRPGLAFTTLTLLDSTPPSEVQEEFYQARKKVSDEVANLPPGVIGPM-VN 137 Query: 136 RGINDVAVTVLTLSPKPEAAERWSDKDLFELADKLRSELIKVDNVGLTYVSGGSAQQIRV 195 DV + L + E + L A+ LR L+ V V + G +++I V Sbjct: 138 DEYADVTFALFALKAQGE-----PQRVLVRDAETLRQRLLHVPGVKKVNIIGEQSERIYV 192 Query: 196 EPDPEKLSLFGVTLQQLVAKVKEANRSFVAGQVRDAG---LVRNVAAGQTLTGIPDIGLL 252 E ++L+ GV+ Q++ A + N AG V G +R A L I D ++ Sbjct: 193 EFSHDRLATLGVSPQEVFAALNNQNALTAAGSVETKGPQVFIRLDGAFDELQKIRDTPVV 252 Query: 253 LIATRDGRPIYVKDVASVAIG---PNTVEHRVWNDARDAAGQWRRAPAVSLALAKRAGAN 309 GR + + D+A+V G P T R GQ PA+ L + R G N Sbjct: 253 ----SQGRTLKLSDIATVKRGYEDPATFMVR-------NGGQ----PALLLGIVMREGWN 297 Query: 310 AVVVSADIAPRLDELKAHLVPDDIQITVTRDYGETANEKANELLFHLALATVSIVVLIAI 369 + + + + + A + P + +T D + +E + A + ++++ + Sbjct: 298 GLDLGKALDKEVGAINADM-PLGMSLTKVTDQAVNISAAVDEFMLKFFAALLVVMLVSFV 356 Query: 370 AIGWREAVVTLVVIPTTILLTLFAANLMGYTINRVSLFALIFSIGILVDDAIVIVENIAR 429 ++GWR +V +P T+ + G +R++L +LI ++G+LVDDAI+ +E + Sbjct: 357 SMGWRAGLVVAAAVPLTLAVVFVVMAATGKNFDRITLGSLILALGLLVDDAIIAIEMMVV 416 Query: 430 HWAMHDGRSRLQATVEAVAEVGNPTIIATLTVVAALLPMLFVSGLMGPYMAPIPANASAA 489 M +G SR+ A+ A + P + TL +P F G Y + + A Sbjct: 417 K--MEEGYSRVAASAYAWSHTAAPMLSGTLVTAVGFMPNGFARSTAGEYTSNMFWIVGIA 474 Query: 490 MLFSFFVAVVIAPWLMLKLAPR-DDAAGEHVLHREGPLGRLYRRFATPVVRSKRAAWIFL 548 ++ S+ VAVV P+L +K+ P G H + P Y RF + R W L Sbjct: 475 LIASWVVAVVFTPYLGVKMLPDFKKVEGGHDAIYDTP---RYNRFRALLGRVIARKW--L 529 Query: 549 LGVGVATLLSMALFATKSVTVKLLPFDNKSEIAVMVDLPEGASLEATE-RTLFAASEIAR 607 + V L ++A+ V + P ++ E+ V V +P G S+ T T + +A+ Sbjct: 530 VAGSVVGLFALAILGMAVVKKQFFPISDRPEVLVEVQMPYGTSINQTSAATAKLEAWLAK 589 Query: 608 QLPETTSLQSYAGTAAPFNFNGLVRHYYLREKPELGELQV-NLTARGDRKRASHDIALEL 666 Q E + SY G AP +YL PEL + + R D + + L Sbjct: 590 Q-KEAQIVTSYVGQGAP--------RFYLAMGPELPDSSFAKIVIRTDSQEERDALKQRL 640 Query: 667 RQRLKALDVPNGTSVKVVEVPPGPPVLATLLAEIYGPDAATRRAVTAELKKIFADVPFIV 726 RQ + P V+V ++ GP + + GPDA T R + A+++++ P + Sbjct: 641 RQAIADGLAPEA-RVRVTQLVFGPYSPFPVAYRVTGPDAETLRRIAADVRQVMDASPMMR 699 Query: 727 DIDDSIGEKRPRLRLSIDQDRLEFFAVEQRDVYDTIQALFGGISIGYSHRGEGRNPIEIA 786 ++ G + P L ++ QDRL+ + V +Q L GI + E +++ Sbjct: 700 TVNTDWGMRVPTLHFTLQQDRLQAVGLTSSAVAQQLQFLLNGIPVTAVR--EDIRTVQVT 757 Query: 787 VRLPKRGLAWDEALASTPVPANTLPGSK-TVVELGQVVKATVEQGTPVIFRRDGRFADMV 845 R A D L + TL G+ V L QV K V P+I RRD V Sbjct: 758 AR-----SAGDIRLDPAKIGDFTLAGANGQRVPLSQVGKIDVRMEEPIIRRRDRMPTITV 812 Query: 846 MAELAGRFEAPLYGMMEVASRVAAHDWGDLPKPAISLHGQPTDESRPT---LLWDGEWEI 902 ++A + P +V++ A+S QP E P+ + G E Sbjct: 813 RGDIADGLQPP-----DVST-------------ALSKQLQPIIEKLPSGYRIEQAGSIEE 854 Query: 903 TYVTFRDMGAAFGAAILGIYVLVVAQFGSFRLPLVILTPIPLTLIGILIGHWLLGAPFTA 962 + + M F + ++++ Q S +++ PL LIG++ L G PF Sbjct: 855 SGKATKAMLPLFPIMLAVTLLILIFQVRSIPAMVMVFLTSPLGLIGVVPTLILFGQPFGI 914 Query: 963 TSMIGFIALAGIIVRNSILLVDFIRHSGGHG 993 +++G IAL+GI++RN+++L+ I+H+ G Sbjct: 915 NALVGLIALSGILMRNTLILIGQIQHNKEEG 945