BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0248.0049.p (455 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl1722 [Q] COG2132 Putative multicopper oxidases Atu Agrobacter... 597 e-170 SMa1038 [Q] COG2132 Putative multicopper oxidases Sme Sinorhizob... 597 e-170 SMc02282 [Q] COG2132 Putative multicopper oxidases Sme Sinorhizo... 591 e-168 BH2082 [Q] COG2132 Putative multicopper oxidases Bha Bacillus ha... 116 1e-25 PA3768 [Q] COG2132 Putative multicopper oxidases Pae Pseudomonas... 114 5e-25 >AGl1722 [Q] COG2132 Putative multicopper oxidases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 449 Score = 597 bits (1539), Expect = e-170, Method: Compositional matrix adjust. Identities = 277/423 (65%), Positives = 342/423 (80%), Gaps = 1/423 (0%) Query: 5 MFSRRGFLGSAALVTASAVSGRVQAAAIPEAPTMDKVVMQPPLHPTSGPDYRPVVTLNGW 64 MF+RR LG +A + +SA + +++PEA M+ Q P+ PT+GPDY PVVT+NGW Sbjct: 1 MFNRRQLLGVSAAMVSSAAWAKTSNSSLPEAALMETAATQAPVKPTTGPDYNPVVTINGW 60 Query: 65 SLPWRMNGDWKEFHLVAEPVVREFADGMKGNLWGYNGQAPGPTIEAVEGDKVRIFVTNRL 124 +LP+RMN KEFHLVAEPV RE A+GM LWGYNGQ+PGPTIEAVEGD+VRIFVTN+L Sbjct: 61 TLPFRMNNGVKEFHLVAEPVEREMAEGMTARLWGYNGQSPGPTIEAVEGDRVRIFVTNKL 120 Query: 125 PEHTTVHWHGMIVPSGMDGVGGLNQPHIKPGKTFVYEFEMKHSGTFMYHPHSDEMVQMAM 184 PEHTT+HWHGMI+PSGMDGVGGL+QPHI GKTFVYEF++ SGTFMYHPHSDEMVQMAM Sbjct: 121 PEHTTIHWHGMILPSGMDGVGGLSQPHIPVGKTFVYEFDLVKSGTFMYHPHSDEMVQMAM 180 Query: 185 GMMGMFIVHPRDPAFRPVDRDFVFIMSSYLIDPGTYLPKVNEMTDFNMWTWNSRVYPGID 244 GMMG F++HP+DPAF PVDRDFVF+++++ I+PG +PK+ MTDFN+W WNSRV+PGID Sbjct: 181 GMMGFFVIHPKDPAFMPVDRDFVFLLNAFDINPGASVPKIMTMTDFNLWAWNSRVFPGID 240 Query: 245 PMPIRLGDRIRVRIGNLTMTNHPIHVHGHNFAVTCTDGGWVPVSAQYPETTTDVPVGAVR 304 P+ + DR+RVR+GNLTMTNHPIH+HG++F VTCTDGGWV A++PE + D+PVGA+R Sbjct: 241 PLVVSKNDRVRVRVGNLTMTNHPIHMHGYDFEVTCTDGGWVRPEARWPEVSIDIPVGAMR 300 Query: 305 AFDMLADNPGDWAFHCHKSHHTMNAMGHDMRNFIGVSRKDLAKAVGKLAPDAMVMGSTGM 364 A++ A GDWA HCHKSHHTMNAMGHD+ FIGV +K + + + K+ PD M MG+ GM Sbjct: 301 AYEFDAKYVGDWAIHCHKSHHTMNAMGHDVPTFIGVDKKTVTEKIRKIRPDYMPMGTAGM 360 Query: 365 A-MGNMEMPAPDNTLPMMTGTGQFGPIEMGGMFTVMKIREGLGRDDYADPGPYKYPPGTV 423 A MG MEM P+NT+PMMTG G GPIEMGGMF+V+K+REG+ DY DPG Y+ PPGT Sbjct: 361 ADMGAMEMEIPENTVPMMTGWGPHGPIEMGGMFSVVKVREGISAGDYTDPGWYENPPGTQ 420 Query: 424 AYE 426 A+E Sbjct: 421 AWE 423 >SMa1038 [Q] COG2132 Putative multicopper oxidases Sme Sinorhizobium meliloti Length = 449 Score = 597 bits (1538), Expect = e-170, Method: Compositional matrix adjust. Identities = 278/423 (65%), Positives = 340/423 (80%), Gaps = 1/423 (0%) Query: 5 MFSRRGFLGSAALVTASAVSGRVQAAAIPEAPTMDKVVMQPPLHPTSGPDYRPVVTLNGW 64 MF+RR LG++A + ++A + +P+A M+ Q PL PTSGPDY PVVTLNGW Sbjct: 1 MFNRRQLLGASAALVSTAAWAKTSNMGLPDAAVMETAETQGPLKPTSGPDYNPVVTLNGW 60 Query: 65 SLPWRMNGDWKEFHLVAEPVVREFADGMKGNLWGYNGQAPGPTIEAVEGDKVRIFVTNRL 124 +LP RMN KEFHLVAEPV RE A+ M LWGYNGQ+PGPTIEAVEGD+VRIFVTN+L Sbjct: 61 TLPHRMNNGVKEFHLVAEPVEREMAEDMTAYLWGYNGQSPGPTIEAVEGDRVRIFVTNKL 120 Query: 125 PEHTTVHWHGMIVPSGMDGVGGLNQPHIKPGKTFVYEFEMKHSGTFMYHPHSDEMVQMAM 184 PEHTT+HWHGMI+PSGMDGVGGL+QPHI GKTFVYEF++ SGTFMYHPHSDEMVQMAM Sbjct: 121 PEHTTIHWHGMILPSGMDGVGGLSQPHIPVGKTFVYEFDLVKSGTFMYHPHSDEMVQMAM 180 Query: 185 GMMGMFIVHPRDPAFRPVDRDFVFIMSSYLIDPGTYLPKVNEMTDFNMWTWNSRVYPGID 244 GMMG F++HP+DP F PVDRDFVF++++Y IDPG+Y+P++ EMTDFNMW WNSR++P I Sbjct: 181 GMMGFFVIHPKDPKFMPVDRDFVFLLNAYDIDPGSYVPRIMEMTDFNMWCWNSRIFPDIS 240 Query: 245 PMPIRLGDRIRVRIGNLTMTNHPIHVHGHNFAVTCTDGGWVPVSAQYPETTTDVPVGAVR 304 P+ + DR+RVR+GNLTMTNHPIH+HG++F VTCTDGGWV A++PE + D+PVGA+R Sbjct: 241 PLVVSKNDRVRVRVGNLTMTNHPIHMHGYDFEVTCTDGGWVRPEARWPEVSIDIPVGAMR 300 Query: 305 AFDMLADNPGDWAFHCHKSHHTMNAMGHDMRNFIGVSRKDLAKAVGKLAPDAMVMGSTGM 364 A++ A GDWA HCHKSHHTMNAMGHD+ FIGV + +A+ + KL P+ M MG+ GM Sbjct: 301 AYEFDAKYAGDWAIHCHKSHHTMNAMGHDIPTFIGVDKSKVAEKIKKLRPEYMPMGTKGM 360 Query: 365 A-MGNMEMPAPDNTLPMMTGTGQFGPIEMGGMFTVMKIREGLGRDDYADPGPYKYPPGTV 423 A MG MEM P+NT+PMMTG G GPIEMGGMF+V+K+REG+ DYADPG Y+ PPGT Sbjct: 361 ADMGEMEMEIPENTIPMMTGWGPHGPIEMGGMFSVVKVREGISAGDYADPGWYENPPGTQ 420 Query: 424 AYE 426 A+E Sbjct: 421 AWE 423 >SMc02282 [Q] COG2132 Putative multicopper oxidases Sme Sinorhizobium meliloti Length = 449 Score = 591 bits (1523), Expect = e-168, Method: Compositional matrix adjust. Identities = 273/423 (64%), Positives = 341/423 (80%), Gaps = 1/423 (0%) Query: 5 MFSRRGFLGSAALVTASAVSGRVQAAAIPEAPTMDKVVMQPPLHPTSGPDYRPVVTLNGW 64 MF+RR LG++A + ++A + +PEA M+ Q P+ P SGPDY PVVT+NGW Sbjct: 1 MFNRRQLLGASAALVSTAAWAKTSNMGLPEAAIMETAETQAPVRPASGPDYNPVVTVNGW 60 Query: 65 SLPWRMNGDWKEFHLVAEPVVREFADGMKGNLWGYNGQAPGPTIEAVEGDKVRIFVTNRL 124 + P RMN KEFHLVAEPV RE A+GM LWGYNGQ+PGPTIEAVEGD+VRIFVTN+L Sbjct: 61 TAPHRMNSGVKEFHLVAEPVEREMAEGMTAYLWGYNGQSPGPTIEAVEGDRVRIFVTNKL 120 Query: 125 PEHTTVHWHGMIVPSGMDGVGGLNQPHIKPGKTFVYEFEMKHSGTFMYHPHSDEMVQMAM 184 PE TT+HWHGMI+PSGMDGVGGL+QPHI PGKTFVYEF++ SGTFMYHPHSDEMVQMAM Sbjct: 121 PEPTTIHWHGMILPSGMDGVGGLSQPHIPPGKTFVYEFDLVKSGTFMYHPHSDEMVQMAM 180 Query: 185 GMMGMFIVHPRDPAFRPVDRDFVFIMSSYLIDPGTYLPKVNEMTDFNMWTWNSRVYPGID 244 GMMG F++HP+DP F PVDRDFVF++++Y I+PG+Y+P+V EMT+FNMW WNSR++P I Sbjct: 181 GMMGFFVIHPKDPKFMPVDRDFVFLLNAYDIEPGSYVPRVMEMTNFNMWCWNSRIFPDIS 240 Query: 245 PMPIRLGDRIRVRIGNLTMTNHPIHVHGHNFAVTCTDGGWVPVSAQYPETTTDVPVGAVR 304 P+ + DR+RVR+GNLTMTNHPIH+HG++F VTCTDGGWV A++PE + D+PVGA+R Sbjct: 241 PLVVSKNDRVRVRVGNLTMTNHPIHMHGYDFEVTCTDGGWVRPEARWPEVSIDIPVGAMR 300 Query: 305 AFDMLADNPGDWAFHCHKSHHTMNAMGHDMRNFIGVSRKDLAKAVGKLAPDAMVMGSTGM 364 A++ A G WA HCHKSHHTMNAMGHD+ FIGV +K++A+ + K+ P+ M MG+ GM Sbjct: 301 AYEFDAKYAGAWAIHCHKSHHTMNAMGHDIPTFIGVDKKEVAQKIRKVRPEYMPMGTAGM 360 Query: 365 A-MGNMEMPAPDNTLPMMTGTGQFGPIEMGGMFTVMKIREGLGRDDYADPGPYKYPPGTV 423 + MG MEM P+NT+PMMTG G GPIEMGGMF+V+K+REG+ DDY+DPG Y+ PPGT Sbjct: 361 SDMGKMEMELPENTIPMMTGWGPHGPIEMGGMFSVVKVREGISADDYSDPGWYENPPGTQ 420 Query: 424 AYE 426 A+E Sbjct: 421 AWE 423 >BH2082 [Q] COG2132 Putative multicopper oxidases Bha Bacillus halodurans Length = 500 Score = 116 bits (291), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 78/268 (29%), Positives = 118/268 (44%), Gaps = 26/268 (9%) Query: 75 KEFHLVAEPVVREFADGMKGNLWGYNGQAPGPTIEAVEGDKVRIFVTNRLPEHTTVHWHG 134 K F+L F D + + W YNG PG I EGD+V I V N L T +H HG Sbjct: 49 KVFNLEVTETHWMFNDEVMMDAWTYNGTLPGQEIRVQEGDEVVINVKNSLNVPTALHLHG 108 Query: 135 MIVPSGMDGVGGLNQPHIKPGKTFVYEFEMKHSGTFMYHPHSDEMVQMAMGMMGMFIVHP 194 VP+ MDGV G+ Q I PG+ F YE++ GT+ YH H D Q+ G+ G+FIV P Sbjct: 109 FPVPNEMDGVPGVTQNAIMPGEEFTYEYQANVPGTYWYHSHQDGATQVDRGLYGVFIVEP 168 Query: 195 RDPAFRPVDRDFVFIMSSYLI----------------------DPGTYLPKVNEMTDFNM 232 DP D D ++ + D ++ +NEM ++ Sbjct: 169 VDP--ESYDTDVAIVIDEFASMGMGMGMDHSTMDHGDMEHDGNDDMSHSEMMNEM--YDT 224 Query: 233 WTWNSRVYPGIDPMPIRLGDRIRVRIGNLTMTNHPIHVHGHNFAVTCTDGGWVPVSAQYP 292 N + P I+ + + G+R+++R N + + + H+F +T DG V Sbjct: 225 MVINGKADPQIESINVVEGNRVKLRFVNAGLFTQVVSIPEHSFKITHYDGQPVNEPDVLQ 284 Query: 293 ETTTDVPVGAVRAFDMLADNPGDWAFHC 320 +T + +++ DNPG W Sbjct: 285 DTAFRIAPAERYDLEIIMDNPGAWGIQV 312 Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 67/259 (25%), Positives = 109/259 (42%), Gaps = 38/259 (14%) Query: 100 NGQAPGPTIEA---VEGDKVRIFVTN--------RLPEHT--TVHWHGMIVPSGMDGVGG 146 NG+A P IE+ VEG++V++ N +PEH+ H+ G P V Sbjct: 228 NGKAD-PQIESINVVEGNRVKLRFVNAGLFTQVVSIPEHSFKITHYDGQ--PVNEPDVLQ 284 Query: 147 LNQPHIKPGKTFVYEFEMKHSGTFMYHPHSDEMVQMAMGMMGMFIVHPRDPAFRPVDRDF 206 I P + + E M + G + ++E + ++ + D + VD Sbjct: 285 DTAFRIAPAERYDLEIIMDNPGAWGIQVFAEENQERLQALIPLVYEEYEDEELQTVDS-- 342 Query: 207 VFIMSSYLIDPGTY-LPKVNEMTDF--------------NMWTWNSRVYPGIDPMPIRLG 251 +SS+ D TY +PK ++ D + +T N + +P + + G Sbjct: 343 ---ISSFF-DLTTYGIPKELDIGDITKEYDMLLGSDDGGDTFTINGKKFPNHEIYDVEEG 398 Query: 252 DRIRVRIGNLTMTNHPIHVHGHNFAVTCTDGGWVPVSAQYPETTTDVPVGAVRAFDMLAD 311 D ++ I N T +HP+H+HG F V + GG + + T +V G A Sbjct: 399 DMVKFTIINDTDFDHPMHLHGDFFHV-ISKGGKAIQGSPVLKDTLNVRPGETYEIVFEAK 457 Query: 312 NPGDWAFHCHKSHHTMNAM 330 NPG+W FHCH+ HH M Sbjct: 458 NPGNWMFHCHEFHHASGGM 476 >PA3768 [Q] COG2132 Putative multicopper oxidases Pae Pseudomonas aeruginosa Length = 463 Score = 114 bits (285), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 66/197 (33%), Positives = 107/197 (54%), Gaps = 14/197 (7%) Query: 76 EFHLVAEPVVREFADGMKGNLWGYNGQAPGPTIEAVEGDKVRIFVTNRLPEHTTVHWHGM 135 ++ L+A P+ E G Y GQ PG + A +G+ +R+ TNRL E TT+HWHG+ Sbjct: 39 DYELIAAPLDLEIVPGFSSPALAYGGQCPGVELRAKQGEWLRVRFTNRLDEPTTIHWHGI 98 Query: 136 IVPSGMDGVGGLNQPHIKPGKTFVYEFEMKHSGTFMYHPHSDEMVQMAMGMMGMFIVHPR 195 +P MDGV ++QP ++PG++F+Y+F+ + +G++ YHPH Q+ G++G I+ R Sbjct: 99 RLPIEMDGVPYISQPPVQPGESFIYQFKTQDAGSYWYHPHLMSSEQLGRGLVGPLIIEER 158 Query: 196 DP-AFRPVDRDFVFIMSSYLIDP-GTYLP------KVNEMTDFNMWTWNSRVYPGIDPMP 247 +P FR + V + ++ +D G + P E T T N + P ID Sbjct: 159 EPTGFR---HEKVLCLKTWHVDEQGAFTPFSVPRQAAREGTRGRYSTINGKHVPTID--- 212 Query: 248 IRLGDRIRVRIGNLTMT 264 + G +RVR+ N+ T Sbjct: 213 LPAGQIVRVRLLNVDNT 229