BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0248.0022.p (484 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc02367 [T] COG0642 Signal transduction histidine kinase Sme Si... 412 e-114 AGc1794 [T] COG0642 Signal transduction histidine kinase Atu Agr... 398 e-110 BMEI1328 [T] COG0642 Signal transduction histidine kinase Bme Br... 398 e-110 mlr7697 [T] COG0642 Signal transduction histidine kinase Mlo Mes... 374 e-103 CC2755 [T] COG0642 Signal transduction histidine kinase Ccr Caul... 259 1e-68 >SMc02367 [T] COG0642 Signal transduction histidine kinase Sme Sinorhizobium meliloti Length = 465 Score = 412 bits (1058), Expect = e-114, Method: Compositional matrix adjust. Identities = 231/470 (49%), Positives = 306/470 (65%), Gaps = 22/470 (4%) Query: 7 LIRTTAFRLTLVYLFLFALFAASLLAYFAWNTRRLITEQITTTVNVEISEITDIYNRRGL 66 L RTTA RL+ +YL LF+L AA L+ Y + RL+ +Q ++ E+++I D+Y+R G+ Sbjct: 7 LFRTTAVRLSALYLVLFSLCAAFLVFYVTGMSERLLQQQTRDSIAAEVTQIADVYDRAGI 66 Query: 67 RGLLGTMGNRALRPGANLYLVTAPNGQMLAGNVGALAPGVMSTQGWTETA--YRRLDDQD 124 GLL ++ RA +PGANLY++ PNG++LAGNV AL PG++ +GW YRR D+ Sbjct: 67 NGLLRSLERRARQPGANLYVIAGPNGEILAGNVAALQPGLLDDEGWKSEPFRYRRFTDES 126 Query: 125 KTD-HRALVRVTQMDNGFRLLVGRDLEERRRLFGIVAKAAQWSILVVVVLGIGGGIF--- 180 + + H AL +V +DNG R+LVGRDL+E + +V +A ++ + ++G+G + Sbjct: 127 RAERHVALAQVLVLDNGLRILVGRDLQEPEKFRVLVRQAL---MVALGIMGLGALVIWFG 183 Query: 181 VARRVLHRIDAMTGTTKRIMAGDLSGRLPVGRSGDELDRLAENLNAMLERIEALMTGLKE 240 + R L RID M+ + +IMAGDLS RLP SGDE DRL+E+LNAMLERIE L GLK+ Sbjct: 184 IGRNALRRIDRMSEASTKIMAGDLSQRLPTSGSGDEFDRLSESLNAMLERIEKLNEGLKQ 243 Query: 241 VSDNIAHDLKTPLTRLRNRAEEALARSGCEADYRAALERTIEESDGLIRTFNALLMIARA 300 VSDNIAHDLKTPLTRLRN+AE ALA + ++ ALE+ I ESD LIRTFNALLMI+R Sbjct: 244 VSDNIAHDLKTPLTRLRNKAEAALADTEG-SNQSGALEQIIAESDQLIRTFNALLMISRV 302 Query: 301 ESGQARGNMDDFDGADVANGIHELYEPLAEDDGMTLQVKTVP-APIHGNRELISQAVANL 359 E+G A M + D A + ELYEPLAED M ++ + P I GNRELISQA+ NL Sbjct: 303 EAGSAVAEMSEVDLARIVADCVELYEPLAEDKEMRIEAEAAPGVAISGNRELISQALGNL 362 Query: 360 VENAIKYGKPDASVQPLNADAREILIEAQREGDQVLLSVTDHGPGIPEADRKHAVERFVR 419 ++NAIKY + + PL I +E R V+L+V DHGPGIPE R V+RFVR Sbjct: 363 IDNAIKYA--EGAENPL------IRVEMMRSDRHVVLTVADHGPGIPENMRGEVVKRFVR 414 Query: 420 LEASRTLPGSGLGLSLASAVATLHGGELRLGDAHP---GLVATLVLPARA 466 L+ SR+ PG+GLGLSL AV +H G L L GL +V PA A Sbjct: 415 LDESRSKPGTGLGLSLVDAVMEMHRGSLELSATEEDGRGLAVRMVFPAVA 464 >AGc1794 [T] COG0642 Signal transduction histidine kinase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 472 Score = 398 bits (1023), Expect = e-110, Method: Compositional matrix adjust. Identities = 227/474 (47%), Positives = 300/474 (63%), Gaps = 32/474 (6%) Query: 7 LIRTTAFRLTLVYLFLFALFAASLLAYFAWNTRRLITEQITTTVNVEISEITDIYNRRGL 66 L R+TA RL+ +Y+ LFAL AA L+ Y + RL+ +Q V E+S++ IYNR G+ Sbjct: 10 LFRSTAVRLSALYILLFALCAAFLVFYVTALSERLLNQQTRDAVLQEVSDVQRIYNRGGI 69 Query: 67 RGLLGTMGNRALRPGANLYLVTAPNGQMLAGNVGALAPGVMSTQGWTETAYR--RLDDQ- 123 LL M RA +PGA+LY++ PNG++LAGNV ++ PGV +GWT +R R + Sbjct: 70 NPLLRMMERRARQPGASLYIIAGPNGEILAGNVASVQPGVFDKEGWTGFPFRYERYSESG 129 Query: 124 DKTDHRALVRVTQMDNGFRLLVGRDLEERRRLFGIVAKAAQWSILVVVVLGIGGGIFV-- 181 D H A V +DNG R+L+GRDL E + +V A ++V + + GG + + Sbjct: 130 DSVQHLATANVFMLDNGLRILIGRDLGEPTKFRALVRNA----LMVALAIMSGGALLIWF 185 Query: 182 --ARRVLHRIDAMTGTTKRIMAGDLSGRLPVGRSGDELDRLAENLNAMLERIEALMTGLK 239 R L RID M+ TKRI+AGDLS RLP GRSGDE DRL+ +LNAML RIE L GL+ Sbjct: 186 GIGRNALKRIDRMSAATKRIIAGDLSQRLPQGRSGDEFDRLSGSLNAMLGRIEKLNEGLR 245 Query: 240 EVSDNIAHDLKTPLTRLRNRAEEALARSGCEADYRAALERTIEESDGLIRTFNALLMIAR 299 +VSDNIAHDLKTPLTRLRN+A AL + E RAALE I ESD LIRTFNALLMI+R Sbjct: 246 QVSDNIAHDLKTPLTRLRNKAAAALDDND-ETKRRAALEGIIAESDQLIRTFNALLMISR 304 Query: 300 AESGQARGNMDDFDGADVANGIHELYEPLAEDDGMTLQVKTVPA-PIHGNRELISQAVAN 358 E+G M D D + +A ELYEP+AED G+ L+ + P + GNRELI QA++N Sbjct: 305 VEAGSIAAEMTDVDMSAIAADSAELYEPVAEDAGLALESQIEPGLSVQGNRELIGQALSN 364 Query: 359 LVENAIKY---GKPDASVQPLNADAREILIEAQREGDQVLLSVTDHGPGIPEADRKHAVE 415 L++NA+KY G+ D +++++ +E + ++LSV DHGPGIP R ++ Sbjct: 365 LIDNAMKYACEGEGD----------KKLVVRLVKEPEAIVLSVADHGPGIPADKRGEVLK 414 Query: 416 RFVRLEASRTLPGSGLGLSLASAVATLHGGELRLGD------AHPGLVATLVLP 463 RFVRL+ SR+ PG+GLGLSL AV LHGG L L D A PGL ++V P Sbjct: 415 RFVRLDESRSKPGTGLGLSLVEAVMELHGGSLVLSDTDATNTACPGLTISMVFP 468 >BMEI1328 [T] COG0642 Signal transduction histidine kinase Bme Brucella melitensis Length = 467 Score = 398 bits (1022), Expect = e-110, Method: Compositional matrix adjust. Identities = 231/470 (49%), Positives = 303/470 (64%), Gaps = 17/470 (3%) Query: 1 VTAFGKLIRTTAFRLTLVYLFLFALFAASLLAYFAWNTRRLITEQITTTVNVEISEITDI 60 ++ F L+RTTA RL+ +YL LFA+ A +L+ Y + ++ Q + E++ I Sbjct: 1 MSRFSALMRTTAARLSALYLLLFAVGAVALVFYMTNLSASILAGQTQQALGEEVASIGKS 60 Query: 61 YNRRGLRGLLGTMGNRALRPGANLYLVTAPNGQMLAGNVGALAPGVMSTQGWTETA--YR 118 Y R G+ L+ T+ R+ +PGA LYLV P G++LAGNV ++ PGV++T G E A YR Sbjct: 61 YARGGIPQLVRTIDYRSRQPGAYLYLVADPTGRILAGNVESVEPGVLNTDGIIERAFTYR 120 Query: 119 RLDDQ-DKTDHRALVRVTQMDNGFRLLVGRDLEERRRLFGIVAKAAQWSILVVVVLGIGG 177 R +Q + +HRA+ V + NG RLLVGRDL E R ++ + +L + ++G+G Sbjct: 121 RYGEQAPQMEHRAIAVVIALPNGMRLLVGRDLGEPERFRDLIRNSL---VLALGIMGVGA 177 Query: 178 ---GIFVARRVLHRIDAMTGTTKRIMAGDLSGRLPVGRSGDELDRLAENLNAMLERIEAL 234 +FV RR L RID ++ ++RIM GDL+GRLPV SGDE DRL+ NLN ML RI L Sbjct: 178 LLIWLFVGRRALKRIDDVSRASQRIMDGDLTGRLPVNGSGDEFDRLSGNLNVMLARILEL 237 Query: 235 MTGLKEVSDNIAHDLKTPLTRLRNRAEEALARSGCEADYRAALERTIEESDGLIRTFNAL 294 GLK+VSDNIAHDLKTPLTRLRNRAEEAL E +YRAALE I ESD LIRTFNA+ Sbjct: 238 NEGLKQVSDNIAHDLKTPLTRLRNRAEEALGGEKVEPEYRAALEDIIGESDQLIRTFNAI 297 Query: 295 LMIARAESGQARGNMDDFDGADVANGIHELYEPLAEDDGMTLQVKTV-PAPIHGNRELIS 353 LMI+R E+G + N+DD A + + E+YEP+AED G+TL + + +H NREL+ Sbjct: 298 LMISRLEAGYSSENLDDMPVAPIMRDVAEMYEPVAEDAGVTLTLGALDDVALHINRELVG 357 Query: 354 QAVANLVENAIKYGKPDASVQPLNADAREILIEAQREGDQVLLSVTDHGPGIPEADRKHA 413 Q V+NLV+NAIKY + + +L+E ++ V + V D+GPGIP R HA Sbjct: 358 QTVSNLVDNAIKYAGGEGRTATVT-----LLME--KDAQWVRIVVADNGPGIPADKRDHA 410 Query: 414 VERFVRLEASRTLPGSGLGLSLASAVATLHGGELRLGDAHPGLVATLVLP 463 ERFVRLE SRT PGSGLGLSLA +V LHGG LRL D PGL A L P Sbjct: 411 TERFVRLEESRTQPGSGLGLSLAKSVMKLHGGALRLEDNGPGLRAVLEFP 460 >mlr7697 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 485 Score = 374 bits (959), Expect = e-103, Method: Compositional matrix adjust. Identities = 222/489 (45%), Positives = 301/489 (61%), Gaps = 38/489 (7%) Query: 8 IRTTAFRLTLVYLFLFALFAASLLAYFAWNTRRLITEQITTTVNVEISEITDIYNRRGLR 67 ++TTA RL+ +YL LFAL A L+ Y + R++T Q T+N E+ + Y R GL Sbjct: 1 MKTTAARLSALYLLLFALCAVLLVFYMTSLSARMLTAQTQETINDEVLGLARAYQRGGLP 60 Query: 68 GLLGTMGNRALRPGANLYLVTAPNGQMLAGNVGALAPGVMSTQGWTET--AYRRLDD--- 122 L+ + NR+ +PGANLYL+ NGQ+L GNV +L PGV+ T+GWT +Y+R + Sbjct: 61 VLVRVVENRSRQPGANLYLIADANGQILTGNVQSLEPGVIDTEGWTTEPFSYKRFGEGEL 120 Query: 123 -------QDKTD-----------------HRALVRVTQMDNGFRLLVGRDLEERRRLFGI 158 D+T H A+ V ++ N +LVGRDL E R + Sbjct: 121 DRLRSGTSDQTTAPATGDNAAQQAEGEQGHNAIALVLRLPNQMIMLVGRDLGEPERFRAV 180 Query: 159 VAKAAQWSILVVVVLGIGGGIFVARRVLHRIDAMTGTTKRIMAGDLSGRLPVGRSGDELD 218 + +A ++ ++ + G+ FV R L RID+++ ++RIM GDLSGRLPV +GDE D Sbjct: 181 IRRALTLALGMMGLGGLLIWFFVGRAALKRIDSVSEASRRIMGGDLSGRLPVTGAGDEFD 240 Query: 219 RLAENLNAMLERIEALMTGLKEVSDNIAHDLKTPLTRLRNRAEEALARSGCEADYRAALE 278 RL+ENLN+ML RI L GLK+VSDNIAHDLKTPLTRLRNRAE L+ ADYR ALE Sbjct: 241 RLSENLNSMLARIATLNEGLKQVSDNIAHDLKTPLTRLRNRAEATLSGKHRPADYRQALE 300 Query: 279 RTIEESDGLIRTFNALLMIARAESGQARGNMDDFDGADVANGIHELYEPLAEDDGMTLQV 338 TI ESD LI+TFNA+LMI+R E+G + + + D A + ELYEP+AE+ G++L+ Sbjct: 301 STIAESDQLIKTFNAILMISRLEAGYSSEHTNRVDLAAAVRDVAELYEPVAEEAGVSLEA 360 Query: 339 KTVPA-PIHGNRELISQAVANLVENAIKYGKPDASVQPLNADAREILIEAQREGDQVLLS 397 + A + GNRELI QA++N+V+NAIKY D++ +P + + +R ++ L Sbjct: 361 EVNGAFLVDGNRELIGQALSNIVDNAIKYST-DSTSKP------AVRVTLERTHGEIWLC 413 Query: 398 VTDHGPGIP-EADRKHAVERFVRLEASRTLPGSGLGLSLASAVATLHGGELRLGDAHPGL 456 V D+G GIP +ADR A ERFVRLE SR+ PGSGLGLSLA AV T H G L L +PGL Sbjct: 414 VADNGQGIPDDADRARATERFVRLEKSRSQPGSGLGLSLAKAVMTFHYGRLDLLPGNPGL 473 Query: 457 VATLVLPAR 465 + P R Sbjct: 474 SVVMSFPVR 482 >CC2755 [T] COG0642 Signal transduction histidine kinase Ccr Caulobacter vibrioides Length = 468 Score = 259 bits (661), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 181/472 (38%), Positives = 268/472 (56%), Gaps = 25/472 (5%) Query: 6 KLIRTTAFRLTLVYLFLFALFAASLLAYFAWNTRRLITEQITTTVNVEISEITDIYNRRG 65 +L+RTT FRLTL++L LFA A++ L Y T + + ++ E + Y + G Sbjct: 5 RLLRTTPFRLTLLFLALFAAAASAFLGYIYVATAGEVNRRAQAEISREFESLEAAYRQGG 64 Query: 66 LRGLLGTMGNRALRPGANLYLVTAPNGQMLAGNVGALAPGVMSTQGWTETAYRRLD-DQD 124 + L T+ RA LY + +G+ ++G++ + G +++ + D D Sbjct: 65 VDALNQTIVERATSERPFLYFLADKDGKRISGSIEESPVSGFTGDGPEWASFKVTETDLD 124 Query: 125 KTDHRALVRVTQ--MDNGFRLLVGRDLEERRRLFGIVAKAAQWSILVVVVLGIGGGIFVA 182 + +A R Q +DNG L VG D++ + +A + +V++LG+ GG+ ++ Sbjct: 125 GAEVKAAARGVQQRLDNGEILFVGADVDASEAYVRKIVRALWGAGALVILLGMAGGVLIS 184 Query: 183 RRVLHRIDAMTGTTKRIMAGDLSGRLPVGRSGDELDRLAENLNAMLERIEALMTGLKEVS 242 R V + + + GDL R V + DE D LAE LN ML+RIE LM GL+ Sbjct: 185 RNVSRSMQGLVDVVNAVRGGDLHARARVRGTRDEYDELAEGLNDMLDRIERLMGGLRHAG 244 Query: 243 DNIAHDLKTPLTRLRNRAEEAL--ARSGCEADYRAALERTIEESDGLIRTFNALLMIARA 300 D IAHDL++PLTRLR R E AL A +G + D AALE ++++DG+++TFNA+L IAR Sbjct: 245 DAIAHDLRSPLTRLRARMEVALIDAENG-KGDPVAALETALQDADGVLKTFNAVLAIARL 303 Query: 301 ESGQARGNMDDFDGADVANGIHELYEPLAEDDGMTLQVKTVPA-PIHGNRELISQAVANL 359 ++ + + FD +++A + ELYE ED G+ + + VPA I GNRE ++QA+AN+ Sbjct: 304 QAAGSAPDQRQFDASELAGDMAELYELSCEDKGLDFKAEIVPALTIKGNREFLAQALANI 363 Query: 360 VENAIKYGKPDASVQPLNADAREILIEAQREGD-QVLLSVTDHGPGIPEADRKHAVERFV 418 ++NAIKY P+ I++ A+R ++ SVTD GPG+PEADR V+RFV Sbjct: 364 LDNAIKY-TPEGGA---------IMLRARRTSSGELEFSVTDTGPGVPEADRARVVQRFV 413 Query: 419 RLEASRTLPGSGLGLSLASAVATLHGGELRLGDAH-------PGLVATLVLP 463 RLE SR+ PG+GLGLSL SAVAT HGG L L + PGL LVLP Sbjct: 414 RLENSRSEPGAGLGLSLVSAVATSHGGRLELAEGPGEYNGMGPGLRVALVLP 465