BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0248.0020.p (527 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI1330 [O] COG0265 Trypsin-like serine proteases, typically pe... 444 e-124 mlr7692 [O] COG0265 Trypsin-like serine proteases, typically per... 433 e-121 AGc1792 [O] COG0265 Trypsin-like serine proteases, typically per... 430 e-120 SMc02365 [O] COG0265 Trypsin-like serine proteases, typically pe... 427 e-119 mll5022 [O] COG0265 Trypsin-like serine proteases, typically per... 343 4e-94 >BMEI1330 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Bme Brucella melitensis Length = 513 Score = 444 bits (1143), Expect = e-124, Method: Compositional matrix adjust. Identities = 253/472 (53%), Positives = 324/472 (68%), Gaps = 27/472 (5%) Query: 70 QPVGFADIVERVKPSVISVKVNIREKVAKDDSNNDDSPFQP--------GSPMERFFRRF 121 Q GFAD+VE+V+P+V+SV+V +K ++ SN F P G P++RFFR F Sbjct: 49 QQAGFADLVEKVRPAVVSVRV---KKDVQETSNRGPQFFGPPGFDQLPDGHPLKRFFRDF 105 Query: 122 GGP---DGLPPGLRGG---PR-GGGVVTGQGSGFFISADGFAVTNNHVVDGADKVEVTTD 174 G D RG PR G QGSGF IS DG+ VTNNHVV D V D Sbjct: 106 GMEPRGDSRSDNRRGKANKPRPGHERPVAQGSGFVISEDGYVVTNNHVVSDGDAYTVVLD 165 Query: 175 DGKTYSAKVIGTDPRTDLALIKVEG-GSNFQFAKL-SDSKPRIGDWVLAVGNPFGLGGTV 232 DG AK+IG DPRTDLA++K+ F + D+K R+GDWV+AVGNPFGLGGTV Sbjct: 166 DGTELDAKLIGADPRTDLAVLKINAPKRKFVYVAFGDDNKVRVGDWVVAVGNPFGLGGTV 225 Query: 233 TAGIVSASGRDIGNGPYDDFIQIDAPVNKGNSGGPAFDVSGEVMGVNTAIYSPSGGSVGI 292 T+GIVSA GRDIG GPYDDFIQIDA VNKGNSGGPAFD+SGEV+G+NTAI+SPSGGSVGI Sbjct: 226 TSGIVSARGRDIGAGPYDDFIQIDAAVNKGNSGGPAFDLSGEVIGINTAIFSPSGGSVGI 285 Query: 293 AFSIPAQTVKSVVAQLKDKGAVSRGWIGVQIQPVTSDIADSLGMKKAEGALVAEPQANGP 352 AF+IP+ T K VV QL KG+V RGWIGVQIQPVT DIA SLG+ + +GA+VA PQ +GP Sbjct: 286 AFAIPSSTAKQVVDQLIKKGSVERGWIGVQIQPVTKDIAASLGLAEEKGAIVASPQDDGP 345 Query: 353 AAKAGIESGDVITSVNGEPVKDARELARTIGGLAPGNAVKLNVLHKGQDKTVNLTLGQLP 412 AAKAGI++GDVIT+VNGE V+D R+LAR + +APG L V K + + +N+T+ +P Sbjct: 346 AAKAGIKAGDVITAVNGETVQDPRDLARKVANIAPGEKAALTVWRKNKAEEINVTIAAMP 405 Query: 413 NNLEAKADTDKSDKGNSSRGTDVPKLGLTVAPANSVAGAGKEGVVVTEVDPKSAAAERGF 472 N+ + K+ + +D + +G + GLTV P+ GK GVVVT+VDP S AA+RG Sbjct: 406 ND-KGKSGSQSNDN-DGGQGETLDSYGLTVVPSED----GK-GVVVTDVDPDSDAADRGI 458 Query: 473 KEGDVILEVAGKSVGTAGEVRDAITAARNDSKNSVLMRVKSGGSSRFVAVPL 524 + GDVI+ V ++V TAG++ AITAA + +VL++++S SRFVA+P+ Sbjct: 459 RSGDVIVSVNNQTVKTAGDINKAITAAEKSGRKAVLLQLQSNDQSRFVALPI 510 >mlr7692 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Mlo Mesorhizobium loti Length = 516 Score = 433 bits (1114), Expect = e-121, Method: Compositional matrix adjust. Identities = 259/534 (48%), Positives = 340/534 (63%), Gaps = 42/534 (7%) Query: 12 SYKAPKRSLFSARKLALMASVVAGLGAATYGFSPSHNPADLFTTPAHAQVNNEVKKVQQP 71 SY ++ L +A +A V+ G+GA T G SP A V E +VQ Sbjct: 7 SYSRTRKRLLAAAASVAVAGVI-GVGALTSGTSPVLADA----------VRVEAPQVQ-- 53 Query: 72 VGFADIVERVKPSVISVKVNIREKVAKDDSNNDDSPFQ--PGSP-MERFFRRFGGPDGLP 128 GFAD+VERV P+V+SVKV + + DD ++D F P +P + RFF+ F G Sbjct: 54 -GFADVVERVSPAVVSVKVKAKIQPTADDGSDDQDGFDNLPNNPQLRRFFKEFRGF---- 108 Query: 129 PGLRGGPRGGGVV--------------TGQGSGFFISADGFAVTNNHVVDGADKVEVTTD 174 G +GG G QGSGFFIS DG+ VTNNHVV+ V T+ Sbjct: 109 -GDQGGQNDEGHRRFGHRDRSNDQPRPVAQGSGFFISEDGYLVTNNHVVEEGTAFTVVTN 167 Query: 175 DGKTYSAKVIGTDPRTDLALIKVEGGSNFQFAKLSD-SKPRIGDWVLAVGNPFGLGGTVT 233 DGK AK++GTDPRTDLA++KVEGG F + +D SK R+GDWV+AVGNPFGLGGTVT Sbjct: 168 DGKELDAKLVGTDPRTDLAVLKVEGGGKFTYVDFADDSKVRVGDWVVAVGNPFGLGGTVT 227 Query: 234 AGIVSASGRDIGNGPYDDFIQIDAPVNKGNSGGPAFDVSGEVMGVNTAIYSPSGGSVGIA 293 AGIVSA GRDIG GPYDDF+QIDA VN+GNSGGP F+++G+V+G+NTAI+SPSGGSVGIA Sbjct: 228 AGIVSARGRDIGAGPYDDFLQIDASVNRGNSGGPTFNLNGQVVGINTAIFSPSGGSVGIA 287 Query: 294 FSIPAQTVKSVVAQLKDKGAVSRGWIGVQIQPVTSDIADSLGMKKAEGALVAEPQANGPA 353 F IPA T K VV L GAV RGW+GV+IQPVTSDIA+SLG+K GALV+ Q +GP Sbjct: 288 FDIPASTAKQVVEDLMKSGAVQRGWLGVEIQPVTSDIAESLGLKSNNGALVSSAQDDGPG 347 Query: 354 AKAGIESGDVITSVNGEPVKDARELARTIGGLAPGNAVKLNVLHKGQDKTVNLTLGQLPN 413 KAGI +GDVIT V G+ V +ELAR IG +PG +V + V G+ +T+ + LG+LP Sbjct: 348 KKAGITAGDVITQVEGKDVASPKELARLIGAYSPGKSVDVTVWRDGKSQTIKVDLGKLPA 407 Query: 414 NLEAKADTDKSDKGNSSRGTDVPKLGLTVAPANSVAGAGKEGVVVTEVDPKSAAAERGFK 473 + + ++ + ++ + LGLTV + + GK G+VVT+VDP+SAAA+RG + Sbjct: 408 SDKQASNDQQQQPAAPAKPDTLADLGLTVTKSEN----GK-GLVVTDVDPESAAADRGIQ 462 Query: 474 EGDVILEVAGKSVGTAGEVRDAITAARNDSKNSVLMRVKSGGSSRFVAVPLAKG 527 GD+I V V +V A+T A + +VLM++ ++RFVA+P+AKG Sbjct: 463 PGDIITAVNSNEVNGTDDVTKAMTDAVKSGRKAVLMQITRDNNNRFVALPVAKG 516 >AGc1792 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 523 Score = 430 bits (1106), Expect = e-120, Method: Compositional matrix adjust. Identities = 242/520 (46%), Positives = 337/520 (64%), Gaps = 30/520 (5%) Query: 25 KLALMASVVAGLGAATYGFSPSHNPADLFTTPAHAQVNNEVKKVQQPVGFADIVERVKPS 84 K AL A+ V GL A + F P EV Q P FA++V+ V P+ Sbjct: 17 KTALKATTVGGLAALMLSTGIAAPILHSFAAPV------EVTAPQVP-SFANVVDAVSPA 69 Query: 85 VISVKVNIREKVAKDDSNNDDSPF--------QPGSPMERFFRRFGG-----PDGLPPGL 131 V+SV+V + A DDS+N F P++RFF+ FGG D P Sbjct: 70 VVSVRVQSNVQPASDDSSNFSFNFGGRGLDQLPDDHPLKRFFKEFGGQNQDRSDRGPNRH 129 Query: 132 RGGPRGGGVVTGQGSGFFISADGFAVTNNHVVDGADKVEVTTDDGKTYSAKVIGTDPRTD 191 R G +G QGSGFFIS DG+ VTNNHVVD V +DG AK++G DPRTD Sbjct: 130 RDG-KGPLRPVAQGSGFFISEDGYVVTNNHVVDDGSAYTVVMNDGTELEAKLVGRDPRTD 188 Query: 192 LALIKVEGGSNFQFAKLSD-SKPRIGDWVLAVGNPFGLGGTVTAGIVSASGRDIGNGPYD 250 LAL+KV+ F + K +D +K R+GDWV+AVGNPFGLGGTVT+GI+SA GRDIG+GPYD Sbjct: 189 LALLKVDVNRKFTYVKFADDTKIRVGDWVVAVGNPFGLGGTVTSGIISARGRDIGSGPYD 248 Query: 251 DFIQIDAPVNKGNSGGPAFDVSGEVMGVNTAIYSPSGGSVGIAFSIPAQTVKSVVAQLKD 310 D++QIDA VN+GNSGGPAF+++GEV+G+NTAI+SPSGG+VGIAF+IP+ K V+A L+ Sbjct: 249 DYLQIDAAVNRGNSGGPAFNLNGEVVGINTAIFSPSGGNVGIAFAIPSSVAKDVIADLQK 308 Query: 311 KGAVSRGWIGVQIQPVTSDIADSLGMKKAEGALVAEPQANGPAAKAGIESGDVITSVNGE 370 G V RGW+GVQIQPV+ DIA+SLG+ +A+GALV PQ+ P KAGI+ GD+IT+VNG+ Sbjct: 309 DGKVERGWLGVQIQPVSKDIAESLGLAEAKGALVVSPQSGSPGDKAGIKQGDIITAVNGD 368 Query: 371 PVKDARELARTIGGLAPGNAVKLNVLHKGQDKTVNLTLGQLPNNLEAKAD-TDKSDKGNS 429 PVKDAR+L+R IGG+AP + V++++ G+ ++V +TLG L ++ +KA + DKG S Sbjct: 369 PVKDARDLSRRIGGMAPNSKVEISLWRGGKSQSVTVTLGDLTSDEASKATPSQNDDKGGS 428 Query: 430 SRGTD--VPKLGLTVAPANSVAGAGKEGVVVTEVDPKSAAAERGFKEGDVILEVAGKSVG 487 ++ + LGLTV+P++ G+ +T+VDP S AA RG K G+ I V + V Sbjct: 429 QSSSEKVLSSLGLTVSPSDD-----GNGLAITDVDPDSDAAARGLKTGEKITSVNNQQVA 483 Query: 488 TAGEVRDAITAARNDSKNSVLMRVKSGGSSRFVAVPLAKG 527 +A ++ + A+ D ++ L ++++ SRF+A+ + +G Sbjct: 484 SAADIEKILEQAKKDGRSKALFQIQTDDGSRFIALDIDQG 523 >SMc02365 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Sme Sinorhizobium meliloti Length = 504 Score = 427 bits (1097), Expect = e-119, Method: Compositional matrix adjust. Identities = 248/523 (47%), Positives = 331/523 (63%), Gaps = 43/523 (8%) Query: 28 LMASVVAGLGAATYGFSPSHNPADLFTT--PAH-AQVNNEVKKVQQPV--GFADIVERVK 82 L + VAGL A L TT PA AQ E +VQ P FA++V+ V Sbjct: 2 LKTTTVAGLAAV------------LLTTGLPAEVAQSFAEAVRVQAPAVPSFANVVDAVS 49 Query: 83 PSVISVKVNIREKVAKDDSNN---------DDSPFQPGSPMERFFRRFGGPDGLPPGLRG 133 P+V+SV+V RE+V+ D+SN +D P P+ RFFR F + Sbjct: 50 PAVVSVRVQARERVSDDESNFTFDFGGRGFEDLP--EDHPLRRFFREFAPRENDRADRWR 107 Query: 134 ---GPRGGGVVT--GQGSGFFISADGFAVTNNHVVDGADKVEVTTDDGKTYSAKVIGTDP 188 GPRG G + QGSGFFI+ DG+ VTNNHVV V +DG AK++G D Sbjct: 108 DRRGPRGEGRLRPRAQGSGFFITEDGYLVTNNHVVSDGSAFTVIMNDGTELDAKLVGKDS 167 Query: 189 RTDLALIKVEGGSNFQFAKLSD-SKPRIGDWVLAVGNPFGLGGTVTAGIVSASGRDIGNG 247 RTDLA++KV+ F + +D K R+GDWV+AVGNPFGLGGTVTAGI+SA GRDIG+G Sbjct: 168 RTDLAVLKVDDKRKFTYVSFADDEKVRVGDWVVAVGNPFGLGGTVTAGIISARGRDIGSG 227 Query: 248 PYDDFIQIDAPVNKGNSGGPAFDVSGEVMGVNTAIYSPSGGSVGIAFSIPAQTVKSVVAQ 307 PYDD++Q+DA VN+GNSGGP F++SGEV+G+NTAI+SPSGG+VGIAF+IPA K VV Sbjct: 228 PYDDYLQVDAAVNRGNSGGPTFNLSGEVVGINTAIFSPSGGNVGIAFAIPASVAKDVVDS 287 Query: 308 LKDKGAVSRGWIGVQIQPVTSDIADSLGMKKAEGALVAEPQANGPAAKAGIESGDVITSV 367 L G VSRGW+GVQIQPVT DIA+SLG+ +A GALV EPQA P KAGI++GDV+T++ Sbjct: 288 LIKDGTVSRGWLGVQIQPVTKDIAESLGLSEANGALVVEPQAGSPGEKAGIKNGDVVTAL 347 Query: 368 NGEPVKDARELARTIGGLAPGNAVKLNVLHKGQDKTVNLTLGQLPNNLEAKADTD---KS 424 NGEPVKD R+LAR + L PG+ ++ + G+ +TVNL +G LP++ + A + Sbjct: 348 NGEPVKDPRDLARRVAALRPGSTAEVTLWRSGKSETVNLEIGTLPSDAKEPAPATGEAQP 407 Query: 425 DKGNSSRGTDVPKLGLTVAPANSVAGAGKEGVVVTEVDPKSAAAERGFKEGDVILEVAGK 484 D+G + + LGLTV P+ GK GV + VDP S A +RG KEG+ I+ V + Sbjct: 408 DEGQAGEEA-LADLGLTVTPSED----GK-GVTIASVDPDSDAGDRGLKEGEKIVSVNNQ 461 Query: 485 SVGTAGEVRDAITAARNDSKNSVLMRVKSGGSSRFVAVPLAKG 527 V +A +V I A+ D ++ L ++++ SRFVA+P+ +G Sbjct: 462 EVKSADDVLKVINNAKKDGRSKALFQIEAQEGSRFVALPITQG 504 >mll5022 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Mlo Mesorhizobium loti Length = 513 Score = 343 bits (881), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 202/461 (43%), Positives = 290/461 (62%), Gaps = 13/461 (2%) Query: 74 FADIVERVKPSVISVKVNIREKVAKDDSNNDDSPFQPGSPMERFFRRFGGPDGLPPGLRG 133 FA IV KP+V++V ++ + A DD D P SP +++FR+F G G+P + Sbjct: 59 FAPIVAADKPAVVTVTSIMKGQPASDD---DGMPLG-NSPFDQYFRQFFGDQGMP-APQT 113 Query: 134 GPRGGGVVTGQGSGFFISADGFAVTNNHVVDGADKVEVTTDDGKTYSAKVIGTDPRTDLA 193 P+ GSGF ++ADG VTNNHVVDGA ++VT DDG AK++G D + DLA Sbjct: 114 PPQQAQRAEALGSGFIVTADGTVVTNNHVVDGASSIKVTLDDGTELPAKLVGRDAKNDLA 173 Query: 194 LIKVEGGSNFQFAKLSDS-KPRIGDWVLAVGNPFGLGGTVTAGIVSASGRDIGNGPYDDF 252 ++K++ K DS + GD VLA+GNPFG+G TVTAGIVSA GRD+ +GP+DDF Sbjct: 174 VLKIKSDKPLPTVKWGDSDRLMTGDQVLAIGNPFGIGTTVTAGIVSARGRDLHSGPFDDF 233 Query: 253 IQIDAPVNKGNSGGPAFDVSGEVMGVNTAIYSPSGGSVGIAFSIPAQTVKSVVAQLKDKG 312 IQIDAP+N GNSGGP DV+G V+G+NTAIYSP+GGSVG+ F+IP+ + VVA+L G Sbjct: 234 IQIDAPINHGNSGGPLVDVNGNVVGINTAIYSPNGGSVGVGFAIPSDQAQKVVAKLMKDG 293 Query: 313 AVSRGWIGVQIQPVTSDIADSLGMKKAEGALVAEPQANGPAAKAGIESGDVITSVNGEPV 372 ++ G++GV+IQ VT D+A ++G+ A GALV++ + PAA AG+E+GDVIT G+ V Sbjct: 294 SIQYGYLGVEIQEVTPDVASAIGLDHAGGALVSKVNDSSPAASAGVEAGDVITGFAGQDV 353 Query: 373 KDARELARTIGGLAPGNAVKLNVLHKGQDKTVNLTLGQLPNNLEAKADTDKSDKGNSSRG 432 KD ++L+R + +APG L+V KG+ +++ +GQ ++++ A +S ++ +G Sbjct: 354 KDPKDLSRAVADVAPGAKETLDVWRKGKAMQISVEVGQNSDDVK-TASAGESGAPSAEQG 412 Query: 433 TDVPKLGL---TVAP--ANSVAGAGKE-GVVVTEVDPKSAAAERGFKEGDVILEVAGKSV 486 + P +GL + P + AG E G VV V+P AAA G + GD+I+ V V Sbjct: 413 SRAPAIGLGLMDITPDIRQEMNLAGNEHGAVVARVNPDKAAAAAGIQPGDIIVAVNQAPV 472 Query: 487 GTAGEVRDAITAARNDSKNSVLMRVKSGGSSRFVAVPLAKG 527 +A +V AI A + SVL+ V+ G +VAVP A G Sbjct: 473 KSARQVTQAIAQASKSGRKSVLLLVERDGGQLYVAVPFANG 513