BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0246.0026.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VNG1769Cm [R] COG1402 Uncharacterized protein, putative amidase ... 108 9e-24 Rv0695 [R] COG1402 Uncharacterized protein, putative amidase Mtu... 102 1e-21 MT0722 [R] COG1402 Uncharacterized protein, putative amidase MtC... 102 1e-21 alr1374 [R] COG1402 Uncharacterized protein, putative amidase No... 99 1e-20 sll0596 [R] COG1402 Uncharacterized protein, putative amidase Sy... 96 9e-20 >VNG1769Cm [R] COG1402 Uncharacterized protein, putative amidase Hbs Halobacterium sp. NRC-1 Length = 275 Score = 108 bits (271), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 75/227 (33%), Positives = 107/227 (47%), Gaps = 16/227 (7%) Query: 29 STVLIPCGAVEQHGPHLPLCMDADHADAIAARLARHLGRTLIAPTIKVGCSAHHLVFPGT 88 S L+P G+ EQHGPHLP D A+A A +A G L P + VG S HH FPGT Sbjct: 36 SLALVPLGSTEQHGPHLPESTDHRIAEAFARTVADRTG-VLCTPPVNVGVSPHHRQFPGT 94 Query: 89 ISIRPETFESICLDYCTSLARHGFRRILLFSGHIGNFPALQDMLPRLRSAVPADVEIDAY 148 + + P F + +LA HG R++ + H GN L+++ RLR E Y Sbjct: 95 MWVEPPVFRDYVASFTRNLAFHGIDRVVFVNAHGGNVSHLREVGRRLRD------EGTLY 148 Query: 149 CDAVAWIEAWRSAVEQAGGDPNAVGGHADIAETSLMMLLRPDNVRLDRFEVGHLGALSEE 208 W E+ V++ D N G H ET+LM L ++V DR E G ++ Sbjct: 149 AVEWMWDESIPELVDEV-FDQN--GPHGGPKETALMQYLDGEHVHDDRLEDARDGGVASV 205 Query: 209 QLQAMWRNGIKSV------TANGIIGNPFGSTARIGERCLAAIADLL 249 ++G ++ T NG++G+ +TA GER A +D L Sbjct: 206 ADADTIKHGSRTFYDAIDNTDNGVLGDQTDATAETGERLFEAASDQL 252 >Rv0695 [R] COG1402 Uncharacterized protein, putative amidase Mtu Mycobacterium tuberculosis H37Rv Length = 251 Score = 102 bits (253), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 112/237 (47%), Gaps = 31/237 (13%) Query: 20 VSVALAAGVSTVLIPCGAVEQHGPHLPLCMDADHADAIAARLARHL---------GRTLI 70 S L + +++IP G+ EQHGPHLPL D A A+A + L L+ Sbjct: 19 TSSQLPSTSPSIVIPLGSTEQHGPHLPLDTDTRIATAVARTVTARLHAEDLPIAQEEWLM 78 Query: 71 APTIKVGCSAHHLVFPGTISIRPETFESICLDYCTSLARHGFRRILLFSGHIGNFPALQD 130 AP I G S H F GTISI E + ++Y S A RR++ +GH GN AL Sbjct: 79 APAIAYGASGEHQRFAGTISIGTEALTMLLVEYGRSAACWA-RRLVFVNGHGGNVGALTR 137 Query: 131 MLPRLRSAVPADVEIDAYCDAVAWIEAWRSAVEQAGGDPNAVGGHADIAETSLMMLLRPD 190 + LR A+ +C GGDP HA ETS+++ L P Sbjct: 138 AVGLLR----AEGRDAGWCPCTC-----------PGGDP-----HAGHTETSVLLHLSPA 177 Query: 191 NVRLDRFEVGHLGALSEEQLQAMWRNGIKSVTANGIIGNPFGSTARIGERCLAAIAD 247 +VR +R+ G+ L L +M R G+ +V+ G++G+P +TA G R AA+ D Sbjct: 178 DVRTERWRAGNRAPLPV-LLPSMRRGGVAAVSETGVLGDPTTATAAEGRRIFAAMVD 233 >MT0722 [R] COG1402 Uncharacterized protein, putative amidase MtC Mycobacterium tuberculosis CDC1551 Length = 251 Score = 102 bits (253), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 112/237 (47%), Gaps = 31/237 (13%) Query: 20 VSVALAAGVSTVLIPCGAVEQHGPHLPLCMDADHADAIAARLARHL---------GRTLI 70 S L + +++IP G+ EQHGPHLPL D A A+A + L L+ Sbjct: 19 TSSQLPSTSPSIVIPLGSTEQHGPHLPLDTDTRIATAVARTVTARLHAEDLPIAQEEWLM 78 Query: 71 APTIKVGCSAHHLVFPGTISIRPETFESICLDYCTSLARHGFRRILLFSGHIGNFPALQD 130 AP I G S H F GTISI E + ++Y S A RR++ +GH GN AL Sbjct: 79 APAIAYGASGEHQRFAGTISIGTEALTMLLVEYGRSAACWA-RRLVFVNGHGGNVGALTR 137 Query: 131 MLPRLRSAVPADVEIDAYCDAVAWIEAWRSAVEQAGGDPNAVGGHADIAETSLMMLLRPD 190 + LR A+ +C GGDP HA ETS+++ L P Sbjct: 138 AVGLLR----AEGRDAGWCPCTC-----------PGGDP-----HAGHTETSVLLHLSPA 177 Query: 191 NVRLDRFEVGHLGALSEEQLQAMWRNGIKSVTANGIIGNPFGSTARIGERCLAAIAD 247 +VR +R+ G+ L L +M R G+ +V+ G++G+P +TA G R AA+ D Sbjct: 178 DVRTERWRAGNRAPLPV-LLPSMRRGGVAAVSETGVLGDPTTATAAEGRRIFAAMVD 233 >alr1374 [R] COG1402 Uncharacterized protein, putative amidase Nos Nostoc sp. PCC 7120 Length = 262 Score = 99.0 bits (245), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 123/255 (48%), Gaps = 23/255 (9%) Query: 6 LPDELRLELMSFEQVSVALAAGVSTVLIPCGAVEQHGPHLPLCMDADHADAIAARLARHL 65 +P E ++++++ ++ P GA+EQHG HLPL +DA + + L Sbjct: 5 IPPERFFAYLTWKEIEEMPNKENVVIIQPVGAIEQHGLHLPLIVDAAIGVGVLGKALSKL 64 Query: 66 GRTLIA---PTIKVGCSAHHLVFPGTISIRPETFESICLDYCTSLARHGFRRILLFSGHI 122 ++ A PT+ G S H FPGTI++ ET + ++ S+ R GFR+++L + H Sbjct: 65 DASIPAYALPTLYYGKSNEHWHFPGTITLSTETLTATIMEVAESIYRAGFRKLVLMNSHG 124 Query: 123 GNFPALQDMLPRLRSAVPADVEIDAYCDAVAWIEAWR--SAVEQAGGDPNAVGG-HADIA 179 G P++ V D+ + AV + WR ++ A+ G HA A Sbjct: 125 GQ--------PQVMQMVARDLHVKYGDFAVFPLFTWRVPHITKELLSPKEAIQGMHAGDA 176 Query: 180 ETSLMMLLRPDNVRLDRF------EVGHLGALSEE-QLQAMWRNGIKSVTANGIIGNPFG 232 ETS+M+ + PD V+LD+ E LS E +L W K ++ +G+IG+ Sbjct: 177 ETSIMLAILPDQVQLDKAVAEYPPEKPEGSLLSWEGRLPVAWVT--KDISKSGVIGDATT 234 Query: 233 STARIGERCLAAIAD 247 +T G+R L +++D Sbjct: 235 ATKEKGDRILESVSD 249 >sll0596 [R] COG1402 Uncharacterized protein, putative amidase Syn Synechocystis Length = 244 Score = 95.9 bits (237), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 59/186 (31%), Positives = 93/186 (50%), Gaps = 7/186 (3%) Query: 10 LRLELMSFEQVSVALAAGVSTVLIPCGAVEQHGPHLPLCMDADHADAIAARLARHLGRTL 69 ++L L ++ +V L + S ++ P G+ EQHGP + DA A+AIA + G + Sbjct: 1 MQLHLSTWPEVENYLQSS-SGIIFPIGSTEQHGPTGLIGTDAICAEAIAKGVGEATG-AM 58 Query: 70 IAPTIKVGCSAHHLVFPGTISIRPETFESICLDYCTSLARHGFRRILLFSGHIGNFPALQ 129 + PTI VG + HHL FPG+IS+RP T + +DY +SLA GF R +GH GN L+ Sbjct: 59 VGPTINVGMALHHLAFPGSISLRPSTLIQVVMDYVSSLANAGFSRFYFINGHGGNIATLK 118 Query: 130 DMLPRLRSAVPADVEIDAYCDAVAWIEAWRSAVEQAGGD--PNAVGGHADIAETSLMMLL 187 + + + D C W A V Q + + G HA +E ++ + Sbjct: 119 AAFSETYHHLGSHGQ-DVRCQVGNWFMA--RGVYQLAKELYSDQEGSHATPSEVAVTQFV 175 Query: 188 RPDNVR 193 P+ ++ Sbjct: 176 YPEAIK 181