BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0243.0075.p (1033 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4207 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1185 0.0 PA4375 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1063 0.0 VC0164 [V] COG0841 Cation/multidrug efflux pump Vch Vibrio cholerae 1033 0.0 BMEI0893 [V] COG0841 Cation/multidrug efflux pump Bme Brucella m... 999 0.0 mlr3649 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 973 0.0 >PA4207 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1029 Score = 1185 bits (3065), Expect = 0.0, Method: Compositional matrix adjust. Identities = 579/1024 (56%), Positives = 772/1024 (75%), Gaps = 1/1024 (0%) Query: 1 MAFTDIFIKRPVLSVVVSLLILLIGLRAAMVLPIRQYPNLSNTVVTITTSYPGASPELIN 60 M FTD+F++RPVL++VVS LILL+GL + LPIRQYP L ++ +T+TT YPGAS +L+ Sbjct: 1 MTFTDLFVRRPVLALVVSTLILLLGLFSLGKLPIRQYPLLESSTITVTTEYPGASADLMQ 60 Query: 61 GFITTPIEQAVASAEGVDYMTSNSVLGTSTIQVYVKLNHDPNQALTEVLAKVNSVKYLIP 120 GF+T PI QAV+S EG+DY++S SV G S + + + LN D QA+TE +AKVNSV+Y +P Sbjct: 61 GFVTQPIAQAVSSVEGIDYLSSTSVQGRSVVTIRMLLNRDSTQAMTETMAKVNSVRYKLP 120 Query: 121 KEAFDPVVTKATGDTIAVMYLGFSSEELTGSSISDYLTRVVQPVLSTVDGVASADILGGQ 180 + A+D V+ +++G+T AV Y+GFSS+ L +++DYL+RVV+P+ S++DGVA GGQ Sbjct: 121 ERAYDSVIERSSGETTAVAYVGFSSKTLPIPALTDYLSRVVEPMFSSIDGVAKVQTFGGQ 180 Query: 181 TFAMRVWLDPTRMAGRGVSPNDVAAAIAANNFQAAAGQTKGFFIVSNVSANTDLQNIDQF 240 AMR+WLD R+AGRG++ +DVA AI NN+QAA G KG +++SNV NTDL N+D F Sbjct: 181 RLAMRLWLDADRLAGRGLTASDVAEAIRRNNYQAAPGMVKGQYVLSNVRVNTDLTNVDDF 240 Query: 241 KRMIVKAKDGGFVRIEDIATVELAAQSTDASVAFNGEHAIFIGIKATPQGNPLTLVKGVR 300 + M+++ G VR+ D+ TVEL A +T+ S +G+ A+ +G+ TP GNPL +V G+R Sbjct: 241 REMVIRNDGNGLVRLRDVGTVELGAAATETSALMDGDPAVHLGLFPTPTGNPLVIVDGIR 300 Query: 301 ALFPDLERNLPPSMKMKVAYDSTKFIQSSIDEVEKTLTEAVLIVVVVIFLFLASLRSVII 360 L P++++ LPP +++ +AY++++FIQ+SIDEV +TL EA+LIVV+VI+L L SLRSV+I Sbjct: 301 KLLPEIQKTLPPDVRVDLAYETSRFIQASIDEVVRTLVEALLIVVLVIYLCLGSLRSVLI 360 Query: 361 PVVTIPLSLIGVCILMLAAGFSFNLLTLLAMVLAIGLVVDDAIVVVENIHRHLEEGLPPV 420 PV TIPLS++G LMLA GFS NLLTLLAMVLAIGLVVDDAIVVVEN+HRH+EEG PV Sbjct: 361 PVATIPLSMLGAAALMLAFGFSVNLLTLLAMVLAIGLVVDDAIVVVENVHRHIEEGKSPV 420 Query: 421 QASLKGAREIVGPVVSMTITLAAVYAPIGFLGGVTGTLFREFAFTLAGSVIVSGVIALTL 480 A+L GARE+ GPV++MTITLAAVY PIG +GG+TG LFREFA TLAG+VIVSGV+ALTL Sbjct: 421 AAALIGAREVAGPVIAMTITLAAVYTPIGLMGGLTGALFREFALTLAGAVIVSGVVALTL 480 Query: 481 SPMMCSVFLKSAE-EGRFARLVNRVFGGLTRAYGRQLDRSLDYRPITALFAVTILGLVGF 539 SP+M S+ L++ + EGR R FGGLTR YG+ L+ SL +R +T A+ + + Sbjct: 481 SPVMSSLLLQAHQNEGRMGRAAEWFFGGLTRRYGQVLEFSLGHRWLTGGLALLVCISLPL 540 Query: 540 LYMHIQKELAPQEDQGIVFAVTKAPKYANIDYIDFYGDKMDKEFQKFPETDLRFILNGIT 599 LY ++ELAP EDQ V KAP++AN+DY++ + K+D+ + PET +I+NG Sbjct: 541 LYSMPKRELAPTEDQAAVLTAIKAPQHANLDYVELFARKLDQVYTSIPETVSTWIINGTD 600 Query: 600 GPQGGFAGMLLKPWDERKRSAQALQPLVQAELSKIEGISAFAFSLPPLPGGPGGLPVQMV 659 GP F G+ L W++R+R A A+Q +Q ++ +EG S FAF L LPG GGLPVQMV Sbjct: 601 GPAASFGGINLAAWEKRERDASAIQSELQGKVGDVEGSSIFAFQLAALPGSTGGLPVQMV 660 Query: 660 ISSTAGFQQVFDQMSKLKDAARKSGLFIVTDSDLDFNQPVVRVKVDRSKASDLGITMQSI 719 + S + ++ M ++K AR+SGLF+V DSDLD+N PVV+V++DR+KA+ LGI MQ I Sbjct: 661 LRSPQDYPVLYRTMEEIKQKARQSGLFVVVDSDLDYNNPVVQVRIDRAKANSLGIRMQDI 720 Query: 720 GGALATLLGGNYVNRFNLEGRSYQVIPQVPRASRLAPEAFNDYYVPTATGQLVRLSTVVS 779 G +LA L+G NYVNRF +EGRSY VIPQ R R P+A +V T G LV LSTVV Sbjct: 721 GESLAVLVGENYVNRFGMEGRSYDVIPQSLRDQRFTPQALARQFVRTQDGNLVPLSTVVR 780 Query: 780 VETGVDPNALTHYNQLNCATFQAVPMPGVSMGQAVEFLQGEAKKLPSGFSYDFLADSRQY 839 V V+PN L ++Q N AT QA+P PGVSMGQAV FL A+ LP+GFS+D+ +DSRQY Sbjct: 781 VALQVEPNKLIQFDQQNAATLQAIPAPGVSMGQAVAFLDDVARGLPAGFSHDWQSDSRQY 840 Query: 840 VHEGNQLLVTFAFAIIIIFLVLAAQFESLRDPFVIMISVPMAIVGALIPLFFGVATMNIY 899 EGN L+ F A+++I+LVLAAQ+ESL DP +I+I+VP++I GAL+PL G ATMNIY Sbjct: 841 TQEGNTLVFAFLAALVVIYLVLAAQYESLADPLIILITVPLSICGALLPLALGYATMNIY 900 Query: 900 TQVGLLTLVGLITKHGILMVEFANELQLNEGLDRRAAIEMAARIRLRPILMTTAAMVTGL 959 TQ+GL+TL+GLI+KHGILMVEFANELQL+E LDRRAAI AA+IRLRP+LMTTAAMV GL Sbjct: 901 TQIGLVTLIGLISKHGILMVEFANELQLHERLDRRAAILRAAQIRLRPVLMTTAAMVFGL 960 Query: 960 LPLLTASGAGAASRFSIGLVVVAGMTIGTLFTLFVLPMVYTVIATDHQAAARSDRAKQIA 1019 +PLL ASGAGAASRF +G+V+V+GM +GTLFTLFVLP VYT++A +H +S R++Q+A Sbjct: 961 VPLLFASGAGAASRFGLGVVIVSGMLVGTLFTLFVLPTVYTLLARNHAEVDKSPRSRQLA 1020 Query: 1020 DYEL 1023 + +L Sbjct: 1021 EADL 1024 >PA4375 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1018 Score = 1063 bits (2749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 554/1005 (55%), Positives = 733/1005 (72%), Gaps = 4/1005 (0%) Query: 1 MAFTDIFIKRPVLSVVVSLLILLIGLRAAMVLPIRQYPNLSNTVVTITTSYPGASPELIN 60 MAFTD FI+RPVL+ VVSLLI+L+G++A L IR+YP + N ++T+TT Y GA+ E I Sbjct: 1 MAFTDPFIRRPVLASVVSLLIVLLGMQAFSKLVIREYPQMENALITVTTLYAGANAETIQ 60 Query: 61 GFITTPIEQAVASAEGVDYMTSNSVLGTSTIQVYVKLNHDPNQALTEVLAKVNSVKYLIP 120 G+IT P++Q++ASAEG+DYMTS S STI +Y ++ + ++ +TE+LAK N VK +P Sbjct: 61 GYITQPLQQSLASAEGIDYMTSVSRQNYSTISIYARIGANTDRLVTELLAKSNEVKSQLP 120 Query: 121 KEAFDPVVTKATGDTIAVMYLGFSSEELTGSSISDYLTRVVQPVLSTVDGVASADILGGQ 180 +A DPV+ K D A+MY+ F SE++ I+DYL+RV+QP L+T+ G+A A+ILG Q Sbjct: 121 PDAEDPVLQKEAADASALMYISFYSEQMNNPQITDYLSRVIQPKLATLPGIAEAEILGNQ 180 Query: 181 TFAMRVWLDPTRMAGRGVSPNDVAAAIAANNFQAAAGQTKGFFIVSNVSANTDLQNIDQF 240 FAMR+WLDP +MA GV+ ++ A+ NF AAAG+ KG +V++V+A+TDL++ F Sbjct: 181 VFAMRLWLDPVKMAAFGVTAGEINQAVQQYNFLAAAGEVKGQLVVTSVNASTDLKSPQAF 240 Query: 241 KRMIVKAKDGGFVRIEDIATVELAAQSTDASVAFNGEHAIFIGIKATPQGNPLTLVKGVR 300 + VK V + D+A VEL A S DA +FNG +++IGIK TP NPL ++K VR Sbjct: 241 AAIPVKTDGDRRVLMGDVARVELGAASYDAISSFNGIPSVYIGIKGTPSANPLDVIKEVR 300 Query: 301 ALFPDLERNLPPSMKMKVAYDSTKFIQSSIDEVEKTLTEAVLIVVVVIFLFLASLRSVII 360 A P+LE LPP++K+ +AYD+T+FIQ+SIDEV KTL EAVLIV+VV+FLFL + RSV+I Sbjct: 301 AKMPELEEQLPPNLKVSIAYDATRFIQASIDEVVKTLGEAVLIVIVVVFLFLGAFRSVLI 360 Query: 361 PVVTIPLSLIGVCILMLAAGFSFNLLTLLAMVLAIGLVVDDAIVVVENIHRHLEEGLPPV 420 PVVTIPLS+IGV M A G+S NLLTLLAMVLAIGLVVDDAIVVVENIHRH+EEG PP Sbjct: 361 PVVTIPLSMIGVLFFMQAMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKPPF 420 Query: 421 QASLKGAREIVGPVVSMTITLAAVYAPIGFLGGVTGTLFREFAFTLAGSVIVSGVIALTL 480 +A+L+GAREI PVVSMTITLAAVYAPIGFL G+TG LF+EFAFTLAG+VI+SG++ALTL Sbjct: 421 EAALEGAREIAVPVVSMTITLAAVYAPIGFLTGLTGALFKEFAFTLAGAVIISGIVALTL 480 Query: 481 SPMMCSVFLKSAEE-GRFARLVNRVFGGLTRAYGRQLDRSLDYRPITALFAVTILGLVGF 539 SPMMCS L+ E A ++ +F GL + Y R L +LD RP+ +FAV +L L+ Sbjct: 481 SPMMCSRLLRHEENPSGLAHRLDLIFEGLKQRYQRALHGTLDTRPVVLVFAVLVLALIPV 540 Query: 540 LYMHIQKELAPQEDQGIVFAVTKAPKYANIDYIDFYGDKMDKEFQKFPETDLRFILNGIT 599 L M +KELAP+EDQGIVF +T +P+ AN+DY++ Y + + F+ FPE F +NG Sbjct: 541 LLMFTKKELAPEEDQGIVFLMTNSPQTANLDYLNRYTAEFEGIFRSFPEYYSAFQINGYN 600 Query: 600 GPQGGFAGMLLKPWDERKRSAQALQPLVQAELSKIEGISAFAFSLPPLPGGPGGLPVQMV 659 G Q G GMLLKPWDER++S L VQA+L++I G+ FAF+LP LPG GLP Q V Sbjct: 601 GVQAGIGGMLLKPWDEREKSQMELLHAVQAKLNEIPGVQIFAFNLPSLPGTGEGLPFQFV 660 Query: 660 ISSTAGFQQVFDQMSKLKDAARKSGLFIVTDSDLDFNQPVVRVKVDRSKASDLGITMQSI 719 +++ ++ + ++K A +SG F D DL F++P + V +DR KA+ +G++MQ + Sbjct: 661 LNTANDYESLLQVAQRVKQRASESGKFAFLDLDLAFDKPELVVDIDREKAAQMGVSMQDL 720 Query: 720 GGALATLLGGNYVNRFNLEGRSYQVIPQVPRASRLAPEAFNDYYVPTATGQLVRLSTVVS 779 G ALA+LLG +NRF ++GRSY+VI QV R R P YYV + GQLV LST++ Sbjct: 721 GVALASLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLGSYYVKSRNGQLVALSTLIE 780 Query: 780 VETGVDPNALTHYNQLNCATFQAVPMPGVSMGQAVEFLQGEAK-KLPSGFSYDFLADSRQ 838 P L + QLN A P+ VSMG+A+E +Q A+ + P GF+ D+ SRQ Sbjct: 781 THERARPRQLNQFQQLNSAIISGFPI--VSMGEAIETVQQIAREEAPRGFAVDYAGASRQ 838 Query: 839 YVHEGNQLLVTFAFAIIIIFLVLAAQFESLRDPFVIMISVPMAIVGALIPLFFGVATMNI 898 YV EG+ LLVTF A+ IIFLVLAAQFES RDP VIM++VP++I GALIPLF GV+++NI Sbjct: 839 YVQEGSALLVTFGLALAIIFLVLAAQFESFRDPLVIMVTVPLSICGALIPLFLGVSSLNI 898 Query: 899 YTQVGLLTLVGLITKHGILMVEFANELQLNEGLDRRAAIEMAARIRLRPILMTTAAMVTG 958 YTQVGL+TL+GLI+KHGIL+VEFAN+L+ +GL RR AIE AA IRLRP+LMTTAAMV G Sbjct: 899 YTQVGLVTLIGLISKHGILIVEFANQLRHEQGLGRREAIEQAAAIRLRPVLMTTAAMVLG 958 Query: 959 LLPLLTASGAGAASRFSIGLVVVAGMTIGTLFTLFVLPMVYTVIA 1003 ++PL+ A+GAGA SRF IG+V+ GM++GTLFTLFVLP +YT++A Sbjct: 959 VIPLILATGAGAVSRFDIGIVIATGMSVGTLFTLFVLPCIYTLVA 1003 >VC0164 [V] COG0841 Cation/multidrug efflux pump Vch Vibrio cholerae Length = 1036 Score = 1033 bits (2672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/1009 (50%), Positives = 700/1009 (69%), Gaps = 2/1009 (0%) Query: 1 MAFTDIFIKRPVLSVVVSLLILLIGLRAAMVLPIRQYPNLSNTVVTITTSYPGASPELIN 60 M FTD+FIKRPVL+V +S LI+L+GL+A + +R+YP ++NTV+T++T Y GAS +LI Sbjct: 1 MRFTDVFIKRPVLAVSISFLIVLLGLQAIFKMQVREYPEMTNTVITVSTGYYGASADLIQ 60 Query: 61 GFITTPIEQAVASAEGVDYMTSNSVLGTSTIQVYVKLNHDPNQALTEVLAKVNSVKYLIP 120 GFIT P+EQAVA A+ +D+MTS SVLG STI V +KLN DPN AL++VLAK NSV+ +P Sbjct: 61 GFITQPLEQAVAQADNIDFMTSQSVLGRSTITVTMKLNTDPNAALSDVLAKTNSVRSQLP 120 Query: 121 KEAFDPVVTKATGDTIAVMYLGFSSEELTGSSISDYLTRVVQPVLSTVDGVASADILGGQ 180 KEA DP VT +TG T AV+Y+GF+S EL S I+DYL RVV P L V+GV+S D+ GG Sbjct: 121 KEAEDPTVTMSTGSTTAVLYIGFTSNELASSQITDYLERVVNPQLYAVNGVSSIDLYGGM 180 Query: 181 TFAMRVWLDPTRMAGRGVSPNDVAAAIAANNFQAAAGQTKGFFIVSNVSANTDLQNIDQF 240 +A+RVWLDP +MA +S DV + + ANN+Q+A GQ G F++ N SA+T + ++ Sbjct: 181 KYALRVWLDPAKMAALNLSAADVMSILNANNYQSATGQAIGEFVLYNGSADTQVSTVEDL 240 Query: 241 KRMIVKAKDGGFVRIEDIATVELAAQSTDASVAFNGEHAIFIGIKATPQGNPLTLVKGVR 300 + ++VKA+ G R+ DIA V LA + NG A+ I A P NP+ + K V Sbjct: 241 ESLVVKAEKGTVTRLGDIAKVTLAKSHDTYRASANGREAVVAAINAAPSANPINIAKDVL 300 Query: 301 ALFPDLERNLPPSMKMKVAYDSTKFIQSSIDEVEKTLTEAVLIVVVVIFLFLASLRSVII 360 + P+L++N+P +++M V YDST I SI EV KT+ EA LIV+VVI LFL SLR+V+I Sbjct: 301 EMLPELQKNMPSNIEMNVLYDSTVAINESIHEVIKTIVEAALIVLVVITLFLGSLRAVLI 360 Query: 361 PVVTIPLSLIGVCILMLAAGFSFNLLTLLAMVLAIGLVVDDAIVVVENIHRHLEEGLPPV 420 P+VTIPLSLIGV ++M GFS+NL+TLLAMVLAIGLVVDDAIVV+EN+ RH++EG P Sbjct: 361 PIVTIPLSLIGVAMVMQMMGFSWNLMTLLAMVLAIGLVVDDAIVVLENVDRHIKEGESPF 420 Query: 421 QASLKGAREIVGPVVSMTITLAAVYAPIGFLGGVTGTLFREFAFTLAGSVIVSGVIALTL 480 +A++ G REI PV++MT+TL AVYAPI +GG+TG+LF+EFA TLAGSV VSG++ALTL Sbjct: 421 RAAIIGTREIAIPVIAMTLTLGAVYAPIALMGGITGSLFKEFALTLAGSVFVSGIVALTL 480 Query: 481 SPMMCSVFLKSAEE-GRFARLVNRVFGGLTRAYGRQLDRSLDYRPITALFAVTILGLVGF 539 SPMMCS LK+ E +F V+ + +T Y R L + +RP+ FA + + Sbjct: 481 SPMMCSKMLKANEAPNKFELKVHHLLDRMTARYERMLTAVMAHRPVVIAFAFIVFASLPM 540 Query: 540 LYMHIQKELAPQEDQGIVFAVTKAPKYANIDYIDFYGDKMDKEFQKFPETDLRFILNGIT 599 L+ I ELAP ED+G++ + P AN+DY+ D ++K PE + G+ Sbjct: 541 LFKFIPSELAPSEDKGVIMLMGTGPSNANLDYLANTMDDVNKILSDQPEVQFAQVFTGVP 600 Query: 600 GPQGGFAGMLLKPWDERKRSAQALQPLVQAELSKIEGISAFAFSLPPLPGGPGGLPVQMV 659 F + PW +R+ S + V + I G++ AF +P LPG GLP+Q V Sbjct: 601 NSNQAFGIASMVPWSQREASQATVTNRVGTLVQDIPGMAVTAFQMPELPGAGSGLPIQFV 660 Query: 660 ISSTAGFQQVFDQMSKLKDAARKSGLFIVTDSDLDFNQPVVRVKVDRSKASDLGITMQSI 719 I++ + F+ +F + + + + +F+ +D DL+F+ +++ +D+ KA G+TMQ I Sbjct: 661 ITTPSNFESLFTIATDVLTEVKANPMFVYSDLDLNFDSATMKINIDKDKAGAYGVTMQDI 720 Query: 720 GGALATLLGGNYVNRFNLEGRSYQVIPQVPRASRLAPEAFNDYYVPTATGQLVRLSTVVS 779 G L+T++ YVNR +L GRSY+VIPQV R RL PE+ N YYV A G+++ L ++V+ Sbjct: 721 GITLSTMMADGYVNRIDLNGRSYEVIPQVERKWRLNPESMNSYYVRAADGKVIPLGSLVT 780 Query: 780 VETGVDPNALTHYNQLNCATFQAVPMPGVSMGQAVEFLQGEA-KKLPSGFSYDFLADSRQ 838 ++ +P +L H+NQLN AT AVP PG +MG A+ + + A KLP G+S+D++ ++RQ Sbjct: 781 IDVVAEPRSLPHFNQLNSATVGAVPAPGTAMGDAINWFENLASSKLPKGYSHDYMGEARQ 840 Query: 839 YVHEGNQLLVTFAFAIIIIFLVLAAQFESLRDPFVIMISVPMAIVGALIPLFFGVATMNI 898 YV EG+ L TF A+ IIFLVLA QFESLRDP VIM+SVP+AI GALI L +G ATMNI Sbjct: 841 YVTEGSALYATFGLALAIIFLVLAIQFESLRDPLVIMVSVPLAICGALIALAWGTATMNI 900 Query: 899 YTQVGLLTLVGLITKHGILMVEFANELQLNEGLDRRAAIEMAARIRLRPILMTTAAMVTG 958 Y+QVGL+TLVGLITKHGIL+ E A E QL+ L R A+ AA++RLRPILMTTAAM+ G Sbjct: 901 YSQVGLITLVGLITKHGILICEVAKEEQLHNKLSRIEAVMHAAKVRLRPILMTTAAMIAG 960 Query: 959 LLPLLTASGAGAASRFSIGLVVVAGMTIGTLFTLFVLPMVYTVIATDHQ 1007 L+PL+ A+GAGAA RFSIG+V+V+G+ IGTLFTLFVLP++Y+ +A H+ Sbjct: 961 LIPLMYATGAGAAQRFSIGIVIVSGLAIGTLFTLFVLPVIYSYLAEKHK 1009 >BMEI0893 [V] COG0841 Cation/multidrug efflux pump Bme Brucella melitensis Length = 1029 Score = 999 bits (2584), Expect = 0.0, Method: Compositional matrix adjust. Identities = 506/1005 (50%), Positives = 706/1005 (70%), Gaps = 2/1005 (0%) Query: 1 MAFTDIFIKRPVLSVVVSLLILLIGLRAAMVLPIRQYPNLSNTVVTITTSYPGASPELIN 60 M F+DIFI+RPVL+ VVSL+I+L+GL+ L +R+YP + TV+T+TT+Y GAS +LI Sbjct: 1 MNFSDIFIRRPVLATVVSLMIVLLGLQGIAQLSVREYPKVDETVITVTTAYAGASADLIQ 60 Query: 61 GFITTPIEQAVASAEGVDYMTSNSVLGTSTIQVYVKLNHDPNQALTEVLAKVNSVKYLIP 120 GFIT PI +AVA+ E +DY+TS+S +ST+ V +KL DP+ ALTEV+AKVN V+ +P Sbjct: 61 GFITAPIAEAVATTENIDYVTSSSRPSSSTVTVQMKLGADPDAALTEVIAKVNQVRGNLP 120 Query: 121 KEAFDPVVTKATGDTIAVMYLGFSSEELTGSSISDYLTRVVQPVLSTVDGVASADILGGQ 180 E+ DPV+ K TG + A MYL + +T I++YL RV+QP +ST+ GVA A+ILGGQ Sbjct: 121 DESDDPVIVKGTGQSFATMYLAAQNPNMTSEQITEYLKRVIQPRMSTIQGVAKAEILGGQ 180 Query: 181 TFAMRVWLDPTRMAGRGVSPNDVAAAIAANNFQAAAGQTKGFFIVSNVSANTDLQNIDQF 240 ++MRVWLDP ++A R ++ +V +AI A+NF +A G+TK ++ ++++ + LQ + F Sbjct: 181 VYSMRVWLDPIQLAARQITAPEVLSAIKASNFLSAPGKTKNEYVATSITLKSTLQTPEAF 240 Query: 241 KRMIVKAKDGGFVRIEDIATVELAAQSTDASVAFNGEHAIFIGIKATPQGNPLTLVKGVR 300 M +KA VR+ D+A VELAA+STD V+FNG F+G+ TP NP+ + VR Sbjct: 241 GAMPIKALGDEVVRLRDVAKVELAAESTDTIVSFNGSAGTFLGVYPTPAANPIDMAAAVR 300 Query: 301 ALFPDLERNLPPSMKMKVAYDSTKFIQSSIDEVEKTLTEAVLIVVVVIFLFLASLRSVII 360 P ++ +LP M + + YD+T+ I SSI+EV T+ EAV IV++VI +FL S RSV+I Sbjct: 301 KELPSIQASLPEGMSLVLVYDATEQISSSINEVFTTIGEAVAIVILVIIVFLGSFRSVLI 360 Query: 361 PVVTIPLSLIGVCILMLAAGFSFNLLTLLAMVLAIGLVVDDAIVVVENIHRHLEEGLPPV 420 P+VTIP+SLIGVC + GFS NLL+LLAMVLAIGLVVDDAIVV+ENIHRH+EEGL P+ Sbjct: 361 PIVTIPISLIGVCFFLYVLGFSINLLSLLAMVLAIGLVVDDAIVVLENIHRHIEEGLHPI 420 Query: 421 QASLKGAREIVGPVVSMTITLAAVYAPIGFLGGVTGTLFREFAFTLAGSVIVSGVIALTL 480 A+ KG +EI G +V+MTITLAAV+ P+GF GG+TG+LFREFAFTLAG+VI+SG+ ALT+ Sbjct: 421 DAAFKGMKEITGSIVAMTITLAAVFTPLGFTGGLTGSLFREFAFTLAGAVIISGIAALTI 480 Query: 481 SPMMCSVFLKSAEEGRFARLVNRVFGGLTRAYGRQLDRSLDYRPITALFAVTILGLVGFL 540 SPMMCS LK ++ RF + ++R F + Y ++ SL+YR IT + ++GL GFL Sbjct: 481 SPMMCSRMLKHGDQTRFQKFIDRTFSRFEKWYHARVSNSLNYRWITLAIVLCLMGLTGFL 540 Query: 541 YMHIQKELAPQEDQGIVFAVTKAPKYANIDYIDFYGDKMDKEFQKFPETDLRFILNGIT- 599 +M+ ELAP+ED G +F++ +AP+YA Y + Y +++D + PE RF + G+ Sbjct: 541 FMNTSSELAPEEDSGALFSMFQAPQYATSAYTNLYAEQIDALTKDLPEQKTRFQIVGMDG 600 Query: 600 GPQGGFAGMLLKPWDERKRSAQALQPLVQAELSKIEGISAFAFSLPPLPGGPGGLPVQMV 659 G G A +LK W+ER RS + +Q + A +SK+ G+ AF F+ P LPG GGLP+ + Sbjct: 601 GTTSGIALWVLKDWNERDRSQKQIQQDLTARISKVAGVQAFIFAPPSLPGTGGGLPISIA 660 Query: 660 ISSTAGFQQVFDQMSKLKDAARKSGLFIVTDSDLDFNQPVVRVKVDRSKASDLGITMQSI 719 + ST QVF ++K A+ SG FI+ + L FN P + +DR +A+ LG+ + I Sbjct: 661 LQSTGPADQVFALAEEIKAEAQASGQFIIVQNSLSFNAPQTTITIDRDRAATLGVQVSDI 720 Query: 720 GGALATLLGGNYVNRFNLEGRSYQVIPQVPRASRLAPEAFNDYYVPTATGQLVRLSTVVS 779 G L L GG + +F+ + SY +I QVP + R PE ++YV + +G +V LS+V+ Sbjct: 721 GSTLGLLTGGASIAKFDRDSNSYDIITQVPDSYRANPEMLGNFYVRSVSGSMVPLSSVIQ 780 Query: 780 VETGVDPNALTHYNQLNCATFQAVPMPGVSMGQAVEFLQGEAK-KLPSGFSYDFLADSRQ 838 + P A+ +NQLN AT A+P+PGV+ GQ ++ L A+ K+P GF D+ SR Sbjct: 781 INENAAPAAIEQFNQLNSATISALPLPGVTTGQGLQTLVDIARSKMPEGFFLDYSCQSRL 840 Query: 839 YVHEGNQLLVTFAFAIIIIFLVLAAQFESLRDPFVIMISVPMAIVGALIPLFFGVATMNI 898 V +GN +L+ F FA+ +I+LVLAAQFES RDPF+IM+SVP++I GA++PL G+ T+NI Sbjct: 841 EVEQGNTILIAFGFAVFVIYLVLAAQFESFRDPFIIMMSVPLSIFGAIVPLNIGLGTLNI 900 Query: 899 YTQVGLLTLVGLITKHGILMVEFANELQLNEGLDRRAAIEMAARIRLRPILMTTAAMVTG 958 YTQVGL+TLVGLITKHGILMVEFAN+ + GL RR AI +AA RLRPILMTTAAM G Sbjct: 901 YTQVGLITLVGLITKHGILMVEFANQQRRLHGLSRRDAIVVAAETRLRPILMTTAAMALG 960 Query: 959 LLPLLTASGAGAASRFSIGLVVVAGMTIGTLFTLFVLPMVYTVIA 1003 ++PL+ A+GAGAA+R+S+GLV+ G+TIGT+FTLFV+PM YT IA Sbjct: 961 VVPLIIATGAGAAARYSMGLVIFTGITIGTIFTLFVVPMFYTFIA 1005 >mlr3649 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1027 Score = 973 bits (2516), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/1007 (48%), Positives = 698/1007 (69%), Gaps = 3/1007 (0%) Query: 1 MAFTDIFIKRPVLSVVVSLLILLIGLRAAMVLPIRQYPNLSNTVVTITTSYPGASPELIN 60 M+F+D+FI+RPVLS V+ LILL+G + L IRQYP + T +TITT+YPGAS +LI Sbjct: 1 MSFSDLFIRRPVLSTVLGCLILLLGFQGIFNLSIRQYPKVDETAITITTAYPGASADLIQ 60 Query: 61 GFITTPIEQAVASAEGVDYMTSNSVLGTSTIQVYVKLNHDPNQALTEVLAKVNSVKYLIP 120 GFI+ PI +AVAS E +DY+TS+S +ST+ V +KL +P+ ALTEVL+KV V+ +P Sbjct: 61 GFISAPIARAVASTENIDYVTSSSRPSSSTVTVQMKLGSNPDVALTEVLSKVQGVRGTLP 120 Query: 121 KEAFDPVVTKATGDTIAVMYLGFSSEELTGSSISDYLTRVVQPVLSTVDGVASADILGGQ 180 + DPV+ K TG A+MY+ + +T +++Y+ RV++P +STV+GVA I G Q Sbjct: 121 DASKDPVIVKGTGQQFAMMYISMQNPNMTKEQLTEYIERVIRPRMSTVEGVADVQIFGAQ 180 Query: 181 TFAMRVWLDPTRMAGRGVSPNDVAAAIAANNFQAAAGQTKGFFIVSNVSANTDLQNIDQF 240 ++MRVW+DP R+A RGV+ +V AI +NF +A G T+ ++VS++S + LQ + F Sbjct: 181 EYSMRVWIDPIRLAARGVTAAEVLTAINNSNFLSAPGNTQNEYVVSSISVRSTLQTPEAF 240 Query: 241 KRMIVKAKDGGFVRIEDIATVELAAQSTDASVAFNGEHAIFIGIKATPQGNPLTLVKGVR 300 + +++ DG VR+ D+A VEL A +TD V+FNG+ F+ I TP NPLT + Sbjct: 241 AELPLRSTDGNVVRLRDVARVELGAANTDTRVSFNGKPGTFLAIFPTPAANPLTTAAALT 300 Query: 301 ALFPDLERNLPPSMKMKVAYDSTKFIQSSIDEVEKTLTEAVLIVVVVIFLFLASLRSVII 360 L P ++ LP M ++V YD+T I +SI+EV KT+ EAV IVVVVI LFL S RSV++ Sbjct: 301 KLVPQIQETLPKGMTIEVVYDATGQISASIEEVFKTIGEAVAIVVVVILLFLGSFRSVMM 360 Query: 361 PVVTIPLSLIGVCILMLAAGFSFNLLTLLAMVLAIGLVVDDAIVVVENIHRHLEEG-LPP 419 P++TIPLSLIGVC L+ A G+S NLL+LLAMVLAIGLVVDDAIVVVENIHRH+EE + P Sbjct: 361 PIITIPLSLIGVCFLLFAVGYSINLLSLLAMVLAIGLVVDDAIVVVENIHRHMEEDHMTP 420 Query: 420 VQASLKGAREIVGPVVSMTITLAAVYAPIGFLGGVTGTLFREFAFTLAGSVIVSGVIALT 479 +QA+ G REI +V+MT+TLAAV+AP+ F GG+TG LFREFA TLAGSV++SGVIA+T Sbjct: 421 MQAAFSGMREIASAIVAMTMTLAAVFAPLAFTGGLTGALFREFAVTLAGSVVLSGVIAVT 480 Query: 480 LSPMMCSVFLKSAEEGRFARLVNRVFGGLTRAYGRQLDRSLDYRPITALFAVTILGLVGF 539 ++PMM + LK+ GRF R+V+ +F + Y R + SL+YRP+T + + ++G+ GF Sbjct: 481 ITPMMSARLLKAGTPGRFQRIVDGIFARVEHVYERAVTGSLNYRPLTLIIVLALVGVTGF 540 Query: 540 LYMHIQKELAPQEDQGIVFAVTKAPKYANIDYIDFYGDKMDKEFQKFPETDLRFILNGIT 599 ++ ELAP+EDQG + ++ AP YA DY + Y ++M + PET +F Sbjct: 541 MFTKTSSELAPEEDQGFLLSLVTAPTYATSDYTETYVNQMLGLVRDIPETRAQFSAVAFG 600 Query: 600 G-PQGGFAGMLLKPWDERKRSAQALQPLVQAELSKIEGISAFAFSLPPLPGGPGGLPVQM 658 G F G K W ERKR+++ LQ + A L+K+ G+ AF F+ P LPG GGLP+ + Sbjct: 601 GTTNSAFVGFAFKDWAERKRNSKELQADITARLAKVAGVQAFVFAPPTLPGSGGGLPIAL 660 Query: 659 VISSTAGFQQVFDQMSKLKDAARKSGLFIVTDSDLDFNQPVVRVKVDRSKASDLGITMQS 718 V+ ST +V+ ++K+ A+ SG FIV + + ++ P V V +DR +A+ L + + Sbjct: 661 VVRSTGDSAEVYKAAEQIKNKAQASGRFIVVQNSMSYDSPQVTVTIDRDRAAALNLPIAD 720 Query: 719 IGGALATLLGGNYVNRFNLEGRSYQVIPQVPRASRLAPEAFNDYYVPTATGQLVRLSTVV 778 IG L L+GG V +F+ + SY +IPQVP+ R PE +Y+V + TG++V LS VV Sbjct: 721 IGRTLTLLVGGAEVAQFDRDSNSYDIIPQVPQQFRDNPERLGEYFVRSVTGEMVPLSAVV 780 Query: 779 SVETGVDPNALTHYNQLNCATFQAVPMPGVSMGQAVEFLQGEAKK-LPSGFSYDFLADSR 837 ++ P A+ +NQLN +T A+P+PGV+ G ++ L+ A++ LP F D+ SR Sbjct: 781 NISNNASPAAIEQFNQLNSSTISALPLPGVTTGDGLKVLEDIARESLPDTFFIDYSGQSR 840 Query: 838 QYVHEGNQLLVTFAFAIIIIFLVLAAQFESLRDPFVIMISVPMAIVGALIPLFFGVATMN 897 Q +GN +L+ FA A+I+I+LVLAAQFES RDP +IM++VP++I GA++PL G+ T+N Sbjct: 841 QEKEQGNTILIAFAAAVIVIYLVLAAQFESFRDPLIIMMAVPLSIFGAIVPLNLGLGTLN 900 Query: 898 IYTQVGLLTLVGLITKHGILMVEFANELQLNEGLDRRAAIEMAARIRLRPILMTTAAMVT 957 IYTQVGL+TL+GLITKHGIL+VEFAN+ + G+ RR AI +A++RLRPILMTTAAM Sbjct: 901 IYTQVGLITLIGLITKHGILLVEFANQQREAHGMRRRDAIIASAKVRLRPILMTTAAMAL 960 Query: 958 GLLPLLTASGAGAASRFSIGLVVVAGMTIGTLFTLFVLPMVYTVIAT 1004 G++PL+T+SGAGAA+R+S+GLV+ G+ +GT+FTLFV+PM YT IA+ Sbjct: 961 GVVPLITSSGAGAAARYSMGLVIFTGILVGTMFTLFVVPMFYTFIAS 1007