BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0243.0027.p (313 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ECs4872 [GER] COG0697 Permeases of the drug/metabolite transport... 86 8e-17 ZyijE [GER] COG0697 Permeases of the drug/metabolite transporter... 86 9e-17 yijE [GER] COG0697 Permeases of the drug/metabolite transporter ... 86 1e-16 BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transport... 81 3e-15 PA1411 [GER] COG0697 Permeases of the drug/metabolite transporte... 80 5e-15 >ECs4872 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 312 Score = 86.3 bits (212), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 122/263 (46%), Gaps = 17/263 (6%) Query: 29 IVVVLAWGINWSVTKSLVEAVPPLWTASIRSWVALLALLVILRASGNLIIPRIADVPVVL 88 +V+ L W +W K + + ++R L L ++L G + P L Sbjct: 27 VVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRGRGMRP--TPFKYTL 84 Query: 89 SVALLHMTFFSTLVAAGLRYLPASKGVVLGYTTPLWVALAAAAARTERLGMLKLVGVALG 148 ++ALL L L A K +L YT P WV + AA ERL + + + Sbjct: 85 AIALLQTCGMVGLAQWALVSGGAGKVAILSYTMPFWVVIFAAVFLGERLRRGQYFAILIA 144 Query: 149 LAGLCVILNPASLDWSNLHVLAGAGMIIIAAICWAANII-----YIRSHRWIATPLQLLL 203 GL ++L P LD+S++ A + I++ + W A+ I Y R R L L Sbjct: 145 AFGLFLVLQPWQLDFSSMK---SAMLAILSGVSWGASAIVAKRLYARHPR--VDLLSLTS 199 Query: 204 WQVLVATLVLTMSALVTEGVP--EVTWSPHLLLLFLYSGFIGTALAYWAMSVVNKSLPAL 261 WQ+L A LV+++ AL+ VP E+ W P + YS + TALA+ V K+LPA Sbjct: 200 WQMLYAALVMSVVALL---VPQREIDWQPTVFWALAYSAILATALAWSLWLFVLKNLPAS 256 Query: 262 TTSLGTTATPIVGIVTAALLLGE 284 SL T A P+ G++ + LLGE Sbjct: 257 IASLSTLAVPVCGVLFSWWLLGE 279 >ZyijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 312 Score = 86.3 bits (212), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 122/263 (46%), Gaps = 17/263 (6%) Query: 29 IVVVLAWGINWSVTKSLVEAVPPLWTASIRSWVALLALLVILRASGNLIIPRIADVPVVL 88 +V+ L W +W K + + ++R L L ++L G + P L Sbjct: 27 VVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRGRGMRP--TPFKYTL 84 Query: 89 SVALLHMTFFSTLVAAGLRYLPASKGVVLGYTTPLWVALAAAAARTERLGMLKLVGVALG 148 ++ALL L L A K +L YT P WV + AA ERL + + + Sbjct: 85 AIALLQTCGMVGLAQWALVSGGAGKVAILSYTMPFWVVIFAAVFLGERLRRGQYFAILIA 144 Query: 149 LAGLCVILNPASLDWSNLHVLAGAGMIIIAAICWAANII-----YIRSHRWIATPLQLLL 203 GL ++L P LD+S++ A + I++ + W A+ I Y R R L L Sbjct: 145 AFGLFLVLQPWQLDFSSMK---SAMLAILSGVSWGASAIVAKRLYARHPR--VDLLSLTS 199 Query: 204 WQVLVATLVLTMSALVTEGVP--EVTWSPHLLLLFLYSGFIGTALAYWAMSVVNKSLPAL 261 WQ+L A LV+++ AL+ VP E+ W P + YS + TALA+ V K+LPA Sbjct: 200 WQMLYAALVMSVVALL---VPQREIDWQPTVFWALAYSAILATALAWSLWLFVLKNLPAS 256 Query: 262 TTSLGTTATPIVGIVTAALLLGE 284 SL T A P+ G++ + LLGE Sbjct: 257 IASLSTLAVPVCGVLFSWWLLGE 279 >yijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 312 Score = 85.5 bits (210), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 122/263 (46%), Gaps = 17/263 (6%) Query: 29 IVVVLAWGINWSVTKSLVEAVPPLWTASIRSWVALLALLVILRASGNLIIPRIADVPVVL 88 +V+ L W +W K + + ++R L L ++L G + P L Sbjct: 27 VVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRGRGMRP--TPFKYTL 84 Query: 89 SVALLHMTFFSTLVAAGLRYLPASKGVVLGYTTPLWVALAAAAARTERLGMLKLVGVALG 148 ++ALL L L A K +L YT P WV + AA ERL + + + Sbjct: 85 AIALLQTCGMVGLAQWALVSGGAGKVAILSYTMPFWVVIFAALFLGERLRRGQYFAILIA 144 Query: 149 LAGLCVILNPASLDWSNLHVLAGAGMIIIAAICWAANII-----YIRSHRWIATPLQLLL 203 GL ++L P LD+S++ A + I++ + W A+ I Y R R L L Sbjct: 145 AFGLFLVLQPWQLDFSSMK---SAMLAILSGVSWGASAIVAKRLYARHPR--VDLLSLTS 199 Query: 204 WQVLVATLVLTMSALVTEGVP--EVTWSPHLLLLFLYSGFIGTALAYWAMSVVNKSLPAL 261 WQ+L A LV+++ AL+ VP E+ W P + YS + TALA+ V K+LPA Sbjct: 200 WQMLYAALVMSVVALL---VPQREIDWQPTVFWALAYSAILATALAWSLWLFVLKNLPAS 256 Query: 262 TTSLGTTATPIVGIVTAALLLGE 284 SL T A P+ G++ + LLGE Sbjct: 257 IASLSTLAVPVCGVLFSWWLLGE 279 >BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 292 Score = 81.3 bits (199), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/285 (22%), Positives = 133/285 (46%), Gaps = 3/285 (1%) Query: 29 IVVVLAWGINWSVTKSLVEAVPPLWTASIRSWVALLALLVILRASGNLIIPRIADVPVVL 88 I V L WG W K + +PPL + +R ++ + L +IL + + + + Sbjct: 9 ISVTLIWGYTWVAMKVGIHDIPPLLFSGLRLFIGAVPLFLILFIQRKKLSIQKEHLKSYI 68 Query: 89 SVALLHMTFFSTLVAAGLRYLPASKGVVLGYTTPLWVALAAAAARTERLGMLKLVGVALG 148 ++LL + ++ G++++ + K VL YT P++V + + + E++ + K +G+ G Sbjct: 69 IMSLLMGLGYMGILTYGMQFVDSGKTSVLVYTMPIFVTVISHFSLNEKMNVYKTMGLVCG 128 Query: 149 LAGLCVILNPASLDWSNLHVLAGAGMIIIAAICWA-ANIIYIRSHRWIATPLQLLLWQVL 207 L GL I L+ + L G +++AA+ W AN+ + I + + W ++ Sbjct: 129 LFGLLFIFGKEMLN-IDQSALFGELCVLVAALSWGIANVFSKLQFKHIDI-IHMNAWHLM 186 Query: 208 VATLVLTMSALVTEGVPEVTWSPHLLLLFLYSGFIGTALAYWAMSVVNKSLPALTTSLGT 267 + ++L + + + E VP W+ + L++G + T + V + A S+ Sbjct: 187 MGAVMLLVFSFIFEAVPSAEWTYQAVWSLLFNGLLSTGFTFVVWFWVLNQIQASKASMAL 246 Query: 268 TATPIVGIVTAALLLGEPIDLSLAIAAALIVGGIALSSLADAPAR 312 P++ + L L E I +++ + A LI GI +++ + + Sbjct: 247 MFVPVLALFFGWLQLHEQITINIILGALLICCGIFMNTFTFSRRK 291 >PA1411 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 303 Score = 80.5 bits (197), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 83/280 (29%), Positives = 129/280 (46%), Gaps = 16/280 (5%) Query: 35 WGINWSVTKSLVEAVPPLWTASIRSWVA--LLALLVILRASGNLIIPRIADVPVVLSVAL 92 WGI K + P+ A+IRS +A L+ LL+ R + L L Sbjct: 20 WGIQQVTIKWAATDIAPVMQAAIRSGIAAALVGLLMCWRGGWEGLRQG------TLGAGL 73 Query: 93 LHMTFFST---LVAAGLRYLPASKGVVLGYTTPLWVALAAAAAR-TERLGMLKLVGVALG 148 L T F+ +A GL+Y AS V YT P++ AL +ERL L+ +GVA+ Sbjct: 74 LTGTLFALEFLFIALGLQYTTASHMSVFLYTAPIFSALGLHFLLPSERLRPLQWLGVAVC 133 Query: 149 LAGLCVILNPASLDWSNL--HVLAGAGMIIIAAICWAANIIYIRSHRWIATPLQL-LLWQ 205 G+ V L W+ + +L G ++A + W A + +R R P L L +Q Sbjct: 134 FGGIAVAFG-GGLSWAEMDGRMLLGDAFGLLAGMSWGATTVAVRGTRLSEAPPSLTLFYQ 192 Query: 206 VLVATLVLTMSALVTEGVPEVTWSPHLLLLFLYSGFIGTALAYWAMSVVNKSLPALTTSL 265 + VA L + AL + EV W+P L+ G + + +Y+ + + A ++ Sbjct: 193 LFVACAGLLLIALFSGQFGEVRWTPVSTASVLFQGVVVSFASYFCWFWLLRRYLANNLAI 252 Query: 266 GTTATPIVGIVTAALLLGEPIDLSLAIAAALIVGGIALSS 305 + TP+ G+ LLLGEP+ L+ AAL++ GI L S Sbjct: 253 FSFMTPLFGVTFGVLLLGEPLSLNFVAGAALVLAGITLVS 292