BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0243.0023.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0007 [GEPR] COG0477 Permeases of the major facilitator superf... 514 e-145 PA5530 [GEPR] COG0477 Permeases of the major facilitator superfa... 499 e-141 AGl1674 [GEPR] COG0477 Permeases of the major facilitator superf... 454 e-127 RSp0075 [GEPR] COG0477 Permeases of the major facilitator superf... 435 e-122 PA0229 [GEPR] COG0477 Permeases of the major facilitator superfa... 416 e-116 >RSp0007 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 447 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 258/429 (60%), Positives = 324/429 (75%), Gaps = 2/429 (0%) Query: 8 PASD--HLDIHDVERRVKAIFIGSVGNLVEWYDFYAYTAFALYFAPAFFPHSDPVVQQLN 65 PA D H HDV RR+++IF GSVGNLVEWYD+Y Y+AFALYFA +FFP D Q LN Sbjct: 15 PAHDAVHEGAHDVRRRLRSIFSGSVGNLVEWYDWYVYSAFALYFAKSFFPKGDQTAQLLN 74 Query: 66 AAVLFAATFLMRPLGGWLFGFIADRYGRRLSLTLSVVCMCFGSLIIAVTPTYATIGIAAP 125 A +FA FL RP+GGWL G ADRYGR+ +L +SVV MC GSLIIA+TP YATIG+AAP Sbjct: 75 TAAVFAVGFLARPVGGWLMGIYADRYGRKRALLVSVVLMCLGSLIIALTPGYATIGVAAP 134 Query: 126 AILALARVIEGLSLGGEYGASATYLSEVADPKHRGFYSSFQYVTLIGGQLTAIIVLLLLQ 185 +L LAR+++GLS+GGEYG SATYLSEVA + RGFYSSFQYVTLI GQL A+ +L+ LQ Sbjct: 135 TLLVLARLLQGLSVGGEYGTSATYLSEVATRESRGFYSSFQYVTLIAGQLVALALLIALQ 194 Query: 186 KVFLTPDELKAWGWRIPFVIGAMLAIVAAVMRRGLHETEAFEEAKKVSKPTGSIVGLLNY 245 + L+P +L AWGWRIPF IGA+ A++A +R + ET++F +K GS+ L + Sbjct: 195 QFVLSPAQLDAWGWRIPFFIGALCALIAMRLRSTMEETQSFTSTTMETKKRGSLRELAKH 254 Query: 246 PRELLLVVGLTAGGTAAFYTFTTYMQTFVKLSVGLTEDQTTFVIFGSLIFATILQPIYGG 305 PR + VVGLT GGT AFYT++ YMQ F+ +VGL++DQ T V +L+ +LQP+ GG Sbjct: 255 PRAVATVVGLTLGGTVAFYTYSIYMQKFLANTVGLSKDQATLVSGATLLLFALLQPVVGG 314 Query: 306 LSDKIGRKPLLIFFGIAGTLGTIPILTALKDTKSPFMAFLLICGAWIFVAGYTSINAIVK 365 LSD++GR+P+LI FG+ GTL T+PI+T + T SP+ AF LI A + V+GYTSINA+VK Sbjct: 315 LSDRVGRRPILIAFGVLGTLFTVPIMTGISQTSSPWTAFFLIMAALVIVSGYTSINAVVK 374 Query: 366 AELFPTNVRALGVGLPYAITVSIFGGTAPAVALYFKSIGHEDWFYYYLSGMIFLSLLIYS 425 AELFPT VRALGVGLPYA+TVSIFGGTA +AL+ K GHE WFY+Y++G IFLSLL+Y Sbjct: 375 AELFPTEVRALGVGLPYALTVSIFGGTAEYIALWLKQAGHEPWFYWYVTGTIFLSLLVYV 434 Query: 426 TMRDTKRDS 434 MRDT+ S Sbjct: 435 FMRDTRAHS 443 >PA5530 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 435 Score = 499 bits (1284), Expect = e-141, Method: Compositional matrix adjust. Identities = 248/434 (57%), Positives = 326/434 (75%), Gaps = 4/434 (0%) Query: 4 QTAQPASDHLDIHDVERRVKAIFIGSVGNLVEWYDFYAYTAFALYFAPAFFPHSDPVVQQ 63 ++A S +R+K+IF GSVGNLVEWYD+Y Y AF+LYFA AFFP D Q Sbjct: 2 ESANAISASAQPRTTSQRIKSIFSGSVGNLVEWYDWYVYAAFSLYFAKAFFPQGDMTAQL 61 Query: 64 LNAAVLFAATFLMRPLGGWLFGFIADRYGRRLSLTLSVVCMCFGSLIIAVTPTYATIGIA 123 LN A +FA FLMRP+GGWL G ADR GR+ +L SV+ MCFGSLIIA+TP+Y TIG+A Sbjct: 62 LNTAAIFAVGFLMRPIGGWLMGIYADRKGRKAALLASVLLMCFGSLIIALTPSYETIGVA 121 Query: 124 APAILALARVIEGLSLGGEYGASATYLSEVADPKHRGFYSSFQYVTLIGGQLTAIIVLLL 183 AP +L +AR+++GLS+GGEYG SATYLSE+A+ + RGF+SSFQYVTLI GQL A+ VL++ Sbjct: 122 APILLVVARLLQGLSVGGEYGTSATYLSEMANKEQRGFFSSFQYVTLISGQLIALAVLIV 181 Query: 184 LQKVFLTPDELKAWGWRIPFVIGAMLAIVAAVMRRGLHETEAFEEAKKVSKPTGSIV-GL 242 LQ+ LT ++L++WGWR+PF IGA+ A+VA +RRG+ ETE+F +KK +P S++ L Sbjct: 182 LQQT-LTVEQLESWGWRVPFFIGALCAVVAMFLRRGMEETESF--SKKKEEPKESLLRTL 238 Query: 243 LNYPRELLLVVGLTAGGTAAFYTFTTYMQTFVKLSVGLTEDQTTFVIFGSLIFATILQPI 302 L +P+E+L VVGLT GGT AFYT+TTYMQ ++ +VG+++ +T + +L +LQPI Sbjct: 239 LRHPKEVLTVVGLTMGGTLAFYTYTTYMQKYLVNTVGMSKTDSTMISAATLFLFMLLQPI 298 Query: 303 YGGLSDKIGRKPLLIFFGIAGTLGTIPILTALKDTKSPFMAFLLICGAWIFVAGYTSINA 362 G LSDKIGR+P+LI FG+ GT+ T PIL+ L S + AF LI A + V+GYTSINA Sbjct: 299 VGALSDKIGRRPILIAFGVLGTVFTYPILSTLHSVDSWWGAFFLIMAALVIVSGYTSINA 358 Query: 363 IVKAELFPTNVRALGVGLPYAITVSIFGGTAPAVALYFKSIGHEDWFYYYLSGMIFLSLL 422 +VKAELFPT +RALGVGLPYA+TVSIFGGTA VAL+FKS+G E FY+Y++ I SLL Sbjct: 359 VVKAELFPTEIRALGVGLPYALTVSIFGGTAEYVALWFKSVGLESGFYWYVTACIACSLL 418 Query: 423 IYSTMRDTKRDSAM 436 +Y M+DT++ S + Sbjct: 419 VYVFMKDTQKHSKI 432 >AGl1674 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 477 Score = 454 bits (1167), Expect = e-127, Method: Compositional matrix adjust. Identities = 241/425 (56%), Positives = 309/425 (72%), Gaps = 4/425 (0%) Query: 17 DVERRVKAIFIGSVGNLVEWYDFYAYTAFALYFAPAFFPHSDPVVQQLNAAVLFAATFLM 76 D + R+K+I GS GNLVEWYD+Y Y+AF LYFAP FFP + + L+AA +FA FLM Sbjct: 53 DQKTRLKSIIGGSAGNLVEWYDWYVYSAFTLYFAPVFFPSGNQTAELLSAAAVFAVGFLM 112 Query: 77 RPLGGWLFGFIADRYGRRLSLTLSVVCMCFGSLIIAVTPTYATIGIAAPAILALARVIEG 136 RP+G W G ADR GR+ LTLSV MC GSL+IAVTP + TIGIAAPAIL AR+++G Sbjct: 113 RPIGAWFMGTYADRKGRKAGLTLSVTLMCLGSLLIAVTPGHETIGIAAPAILVFARLLQG 172 Query: 137 LSLGGEYGASATYLSEVADPKHRGFYSSFQYVTLIGGQLTAIIVLLLLQKVFLTPDELKA 196 +S+GGEYGASATYLSE+A RGF+SSFQYVTLI GQL A+ VLL+LQ+V LTP++L + Sbjct: 173 ISVGGEYGASATYLSEMAGKSRRGFFSSFQYVTLISGQLLALAVLLVLQRV-LTPEQLGS 231 Query: 197 WGWRIPFVIGAMLAIVAAVMRRGLHETEAFEEAK--KVSKPTGSIVGLL-NYPRELLLVV 253 WGWRIPF IG MLAI +RRGL ET++FE AK + KP S L +YPRE L+V+ Sbjct: 232 WGWRIPFFIGGMLAIAVFYIRRGLAETQSFENAKAGEADKPKSSGWALFKHYPREALMVM 291 Query: 254 GLTAGGTAAFYTFTTYMQTFVKLSVGLTEDQTTFVIFGSLIFATILQPIYGGLSDKIGRK 313 LT+GGT AFY +TTY+Q F+ + G +++ T + +L + QP+ G LSD++GRK Sbjct: 292 ALTSGGTLAFYAYTTYLQKFLVNTSGFSKESATEITTAALFVFMLCQPLAGALSDRVGRK 351 Query: 314 PLLIFFGIAGTLGTIPILTALKDTKSPFMAFLLICGAWIFVAGYTSINAIVKAELFPTNV 373 PL++ FGI GTL T I + L T P MAF+L+ + V GYTSINA+VKAE+FP ++ Sbjct: 352 PLMVGFGILGTLFTYLIFSTLATTTDPIMAFVLVLVGLLIVTGYTSINAVVKAEMFPAHI 411 Query: 374 RALGVGLPYAITVSIFGGTAPAVALYFKSIGHEDWFYYYLSGMIFLSLLIYSTMRDTKRD 433 RALGV LPYA+ +IFGGTA VAL FK IGHE+WF++Y++ MI LSL++Y MRDT+ Sbjct: 412 RALGVALPYALANTIFGGTAEFVALKFKQIGHENWFFWYVTIMIALSLVVYVKMRDTRDH 471 Query: 434 SAMHR 438 S +H Sbjct: 472 SHIHE 476 >RSp0075 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 437 Score = 435 bits (1119), Expect = e-122, Method: Compositional matrix adjust. Identities = 222/440 (50%), Positives = 304/440 (69%), Gaps = 4/440 (0%) Query: 1 MSEQTAQPASDHLDIHDVERRVKAIFIGSVGNLVEWYDFYAYTAFALYFAPAFFPHSDPV 60 MS AQ + + HD RR+ AI S GNLVEW+DFY Y +LYFAPAFFP + Sbjct: 1 MSTPAAQASQAVMAPHDTRRRIFAIVGASSGNLVEWFDFYVYAFCSLYFAPAFFPSGNTT 60 Query: 61 VQQLNAAVLFAATFLMRPLGGWLFGFIADRYGRRLSLTLSVVCMCFGSLIIAVTPTYATI 120 Q +N A +FAA FLMRP+GGWLFG IADR+GRR ++ +SV+ MC GSL+IAV P YA I Sbjct: 61 TQLMNTAGVFAAGFLMRPIGGWLFGRIADRHGRRNAMMISVLMMCGGSLVIAVLPIYAQI 120 Query: 121 GIAAPAILALARVIEGLSLGGEYGASATYLSEVADPKHRGFYSSFQYVTLIGGQLTAIIV 180 G AP +L +AR+ +GLS+GGEYG SATY+SEVA RGF++SFQYVTLIGGQL A++V Sbjct: 121 GALAPFLLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLCALLV 180 Query: 181 LLLLQKVFLTPDELKAWGWRIPFVIGAMLAIVAAVMRRGLHETEAFEEAKKVSKPTGSIV 240 L++LQ+V L+ ELKAWGWRIPFV+GA+ A+V+ +RR L ET++ A + +K G+I Sbjct: 181 LVILQQV-LSTAELKAWGWRIPFVVGALSALVSLYLRRSLDETQS--TASREAKHAGTIR 237 Query: 241 GLLNYPRELLLVVGLTAGGTAAFYTFTTYMQTFVKLSVGLTEDQTTFVIFGSLIFATILQ 300 G + L V+G TAGG+ FYTFTTYMQ ++ + G+ + V+ +L LQ Sbjct: 238 GAWQHKGAFLRVIGFTAGGSLIFYTFTTYMQKYLVNTAGMNTKTASNVMTAALFVYMALQ 297 Query: 301 PIYGGLSDKIGRKPLLIFFGIAGTLGTIPILTALKDTKSPFMAFLLICGAWIFVAGYTSI 360 P++G LSD+IGR+ +I FG+ L T+P++ AL +P+ AF L+ A ++ YTSI Sbjct: 298 PVFGALSDRIGRRMSMILFGVGAVLFTVPLMRALGSVTNPYAAFGLVTAALAIISFYTSI 357 Query: 361 NAIVKAELFPTNVRALGVGLPYAITVSIFGGTAPAVALYFKSIGHEDWFYYYLSGMIFLS 420 + ++KAE+FP VRA+GVGL YAI ++FGG+A VAL+FKS G E FY+Y++ + +S Sbjct: 358 SGLIKAEMFPPEVRAMGVGLSYAIANAVFGGSAEYVALWFKSAGRESTFYWYVTTLCAVS 417 Query: 421 LLIYSTMRDTKRDSAMHRHE 440 L++ TM D ++ + RHE Sbjct: 418 LIVSYTMPDPSKEGYL-RHE 436 >PA0229 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 432 Score = 416 bits (1068), Expect = e-116, Method: Compositional matrix adjust. Identities = 221/422 (52%), Positives = 306/422 (72%), Gaps = 3/422 (0%) Query: 16 HDVERRVKAIFIGSVGNLVEWYDFYAYTAFALYFAPAFFPHSDPVVQQLNAAVLFAATFL 75 + +R+ AI S GNLVEW+DFY Y A+YFAPAFFP +P VQ LN A +FAA FL Sbjct: 11 EERRKRIFAIVGASSGNLVEWFDFYVYAFCAIYFAPAFFPSDNPTVQLLNTAGVFAAGFL 70 Query: 76 MRPLGGWLFGFIADRYGRRLSLTLSVVCMCFGSLIIAVTPTYATIGIAAPAILALARVIE 135 MRP+GGW+FG IAD++GR+ ++ +SVV MC GSL IA PTYA+IG APA+L LAR+ + Sbjct: 71 MRPIGGWMFGRIADKHGRKTAMLISVVMMCAGSLAIACMPTYASIGTLAPALLLLARMFQ 130 Query: 136 GLSLGGEYGASATYLSEVADPKHRGFYSSFQYVTLIGGQLTAIIVLLLLQKVFLTPDELK 195 GLS+GGEYG SATY+SEVA RGF++SFQYVTLIGGQL A++V+++LQ++ L+ DEL+ Sbjct: 131 GLSVGGEYGTSATYMSEVALKGQRGFFASFQYVTLIGGQLLAVLVVVILQQL-LSEDELR 189 Query: 196 AWGWRIPFVIGAMLAIVAAVMRRGLHETEAFEEAKKVSKPTGSIVGLLNYPRELLLVVGL 255 AWGWRIPFVIGA+ A++A +RR L+ET + ++ K +G+ L + R V+G Sbjct: 190 AWGWRIPFVIGAITAVIALWLRRSLNETASKSTLER--KESGTFAELFKHKRAFFTVLGF 247 Query: 256 TAGGTAAFYTFTTYMQTFVKLSVGLTEDQTTFVIFGSLIFATILQPIYGGLSDKIGRKPL 315 TAGG+ FYTFTTYMQ ++ + G++ + V+ +L+ ++QP++G LSD+IGRK Sbjct: 248 TAGGSLIFYTFTTYMQKYLVNTAGMSAKTASAVMTFALLAYMLMQPLFGMLSDRIGRKTS 307 Query: 316 LIFFGIAGTLGTIPILTALKDTKSPFMAFLLICGAWIFVAGYTSINAIVKAELFPTNVRA 375 +++FG GTL T+PIL ALK SP+MAF LI A V+ YTSI+ ++KAE+FP VRA Sbjct: 308 MLWFGTLGTLCTLPILLALKTVSSPYMAFFLIILALAIVSLYTSISGLIKAEMFPPEVRA 367 Query: 376 LGVGLPYAITVSIFGGTAPAVALYFKSIGHEDWFYYYLSGMIFLSLLIYSTMRDTKRDSA 435 LGVG+ YA+ +IFGG+A VAL KS+G E+ FY+Y+S M L+LL+ ++ D ++ S Sbjct: 368 LGVGVSYAVGNAIFGGSAEYVALGLKSVGMENVFYWYVSAMCLLALLVCVSLPDLRKVSY 427 Query: 436 MH 437 ++ Sbjct: 428 LN 429