BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0243.0008.p (325 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0874_2 [E] COG4177 ABC-type branched-chain amino acid trans... 198 2e-50 APE2523 [E] COG4177 ABC-type branched-chain amino acid transport... 159 7e-39 BMEII0101 [E] COG4177 ABC-type branched-chain amino acid transpo... 136 6e-32 AF0225 [E] COG4177 ABC-type branched-chain amino acid transport ... 120 4e-27 SMc01950 [E] COG4177 ABC-type branched-chain amino acid transpor... 120 5e-27 >BMEII0874_2 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Bme Brucella melitensis Length = 315 Score = 198 bits (503), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 101/287 (35%), Positives = 181/287 (63%), Gaps = 6/287 (2%) Query: 30 VKDVYVQNIMVLTLMYAALSQSWNILSGYCGQISLGHALYFGLGAYTTALLFTKFGVLPW 89 + + +V +I + ++AALS +WNI+ G+ GQ+SLGHA+++G+G YT +LF G+ PW Sbjct: 15 INNAFVSHIFITICLFAALSTAWNIVGGFAGQMSLGHAVFYGIGGYTGVILF-NMGISPW 73 Query: 90 FGMLAGGAISALIAMALGYPCFRLRGHYFVIATIVIAEIALLLIQNWDW-AGAALGIDIP 148 F M G I+AL+ M + YPCFRL+G ++ +A+I E+ +L ++ W G A G+ I Sbjct: 74 FSMFIGAFIAALVGMVISYPCFRLKGPFYSLASIAFLEVFRVLALHFGWLTGGATGLMIQ 133 Query: 149 VR-GDSWLKFQFTRSKLPYFYFALALACIAWFVTWWLEDSKWGYWWRAVKDNPDAAESLG 207 ++ G W+ F R + P + + +TW + S+ G++ A ++ AA + G Sbjct: 134 LKLGWVWMVF---RERWPSLLIVFGMLLVTLAITWAVRRSRLGFYLVATRERESAARAAG 190 Query: 208 VVVFNSKMGAAAVSAFLVAVGGSFYAQFVSYIDPESVMGFQFSLLMALPAVLGGIGTLWG 267 V ++ A A+S+ L A+ G+F+A ++++I+P ++ FS+ +A+ A++GG+GT+ G Sbjct: 191 VRTVRVRLIAVAISSALCAMLGTFHAMYLTFIEPAAMFSLAFSIQIAMFALIGGLGTVAG 250 Query: 268 PVLGAVILIPLTELTRSFIGGSGRGVDLIVYGTLIVVISLALPRGLV 314 P+LGAV+L+P+TE R+ +G S G+ VYG +++++ L +P G++ Sbjct: 251 PLLGAVLLVPITEWARASLGASALGLHGFVYGLVLILVVLFMPNGIM 297 >APE2523 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Ape Aeropyrum pernix Length = 332 Score = 159 bits (402), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 108/309 (34%), Positives = 175/309 (56%), Gaps = 6/309 (1%) Query: 16 AACLAVIAALVPLFVKDVYVQNIMVLTLMYAALSQSWNILSGYCGQISLGHALYFGLGAY 75 A LAV L+ L K YV N++ L+LMY + +WN+L GY G SLGHA++FG+G Y Sbjct: 23 AMILAVAPVLLDLAGKPFYV-NMIFLSLMYGISAMAWNLLMGYTGLFSLGHAVFFGVGGY 81 Query: 76 TTALLFTKFGVLPWFGMLAGGAISALIAMALGYPCFRLRGHYFVIATIVIAEIALLLIQN 135 T +L ++ V PW G+ G +A++A AL P RLR H+F +ATI + EI L + Sbjct: 82 TVIVLALRYNVTPWIGLPVAGLTAAMLAAALSPPLLRLRSHWFTLATIALGEIFRLSFAH 141 Query: 136 WDWAGAALGIDIPVRGDSWLKFQFTRSKLPYFYFALALACIAWFVTWWLEDSKWGYWWRA 195 WD+ GA+ G+ +P+ S QF + + Y Y A+A+ + W + +SK G++ + Sbjct: 142 WDYVGASAGLQMPISERSIYYVQFAGATV-YSYIAMAILAVELLFLWKIINSKTGFYMQT 200 Query: 196 VKDNPDAAESLGVVVFNSKMGAAAVSAFLVAVGGSFYAQFVSYIDPESVMGF-QFSLLMA 254 ++++ A++LG+ FN K + +SAF + G YA Y+DP +V S +A Sbjct: 201 IREDELVAQTLGINTFNYKALSLVISAFFTGLAGGLYAMRFRYVDPFAVFDLITISTYIA 260 Query: 255 LPAVLGGIGTLWGPVLGAVILIPLTELTRSFIGGSG---RGVDLIVYGTLIVVISLALPR 311 + ++GGI T GP +G+ I +P++E R+ I + G+ + V G ++++ISL P Sbjct: 261 IAGIIGGIYTFLGPQVGSFIFVPISEYVRANIVQAFPRVYGLHVAVLGVILLLISLFAPE 320 Query: 312 GLVSVFSLR 320 G++ R Sbjct: 321 GVLGYIRRR 329 >BMEII0101 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Bme Brucella melitensis Length = 315 Score = 136 bits (343), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 98/305 (32%), Positives = 169/305 (55%), Gaps = 21/305 (6%) Query: 17 ACLAVIAALV----PLFVKDVYVQNIMVLTLMYAALSQSWNILSGYCGQISLGHALYFGL 72 A LA+IAA++ PLF V +Q +M L+ A L+Q+WNI+ G+ G S G+++++GL Sbjct: 6 ALLAIIAAVLALGAPLFASPVMMQ-LMFDALIIATLAQAWNIIGGFTGYASFGNSVFYGL 64 Query: 73 GAYTTALLFTKFGVLPWFGMLAGGAISAL-IAMALGYPCFRLRGHYFVIATIVIAEIALL 131 GAY + +F LP+F A G ++A+ AM +G P RL+GHYF IAT+ + ++ Sbjct: 65 GAYGAGIAMVQFN-LPFFAGAAIGIVAAVVFAMLIGLPILRLKGHYFAIATLALPQVMAA 123 Query: 132 LIQNWDWAGAALGIDIPVRGDSWLKFQFTRSKLPYFYFALALACIAWFVTWWLEDSKWGY 191 + N AG +G+ +P+ + ++ AL L IA V L S++G+ Sbjct: 124 ITANVPVAGENIGLVLPLLNNDTF----------FYESALILLIIATCVVALLTRSRFGF 173 Query: 192 WWRAVKDNPDAAESLGVVVFNSKMGAAAVSAFLVAVGGSFYAQFVSYIDPESVMGFQFSL 251 A+++N + A ++G+ K+ A +S A+ G+ A ++++DPE+ Q ++ Sbjct: 174 GLIAIRENEEGAAAMGINTTLYKILALMLSGAFCAMAGALQAYKITFLDPEAAYQVQLNV 233 Query: 252 LMALPAVLGGIGTLWGPVLGAVILIPLTELTRSFIGGSGRGVDLIVYGTLIVVISLALPR 311 M + AV GG GT++GPV GA+ L + +++ + V + +G +IVV + +PR Sbjct: 234 QMIIMAVFGGAGTIFGPVFGALFL----QWVSNWLSTAYTDVAGMFFGIVIVVAVVLMPR 289 Query: 312 GLVSV 316 GL + Sbjct: 290 GLADL 294 >AF0225 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Afu Archaeoglobus fulgidus Length = 338 Score = 120 bits (301), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 90/311 (28%), Positives = 165/311 (53%), Gaps = 23/311 (7%) Query: 21 VIAALVPLFVKDVYVQNIMVLTLMYAALSQSWNILSGYCGQISLGHALYFGLGAYTTALL 80 ++AA++P + + Y+ I+ L ++A + SW+++ GY GQ++LGH + GLGAY A+L Sbjct: 39 IVAAVMPFILPEAYLY-ILGLAYIFAIMVISWDLMVGYTGQVNLGHTTFVGLGAYVAAIL 97 Query: 81 FTK----FGVLPWFGMLAGGAISALIAMALGYPCFRLRGHYFVIATIVIAEIALLLIQNW 136 T + P ++ GG ++A + +++G RLRG+YF + T ++ + + + W Sbjct: 98 QTPIRAGLSLHPALAIITGGVVAAGVGLSIGIITLRLRGYYFSLVTAILPLVFMQTVFIW 157 Query: 137 -DWAGAALGIDIPVRGDSWLKFQFTRSKLPYFYFALALACIAWFVTWWLEDSKWGYWWRA 195 + G G I + + + +YF+LA+ ++ V + DS+ G + A Sbjct: 158 RELFGGEEGFAI--------ENTMLTTTVEKYYFSLAVLVVSLVVMKKVVDSRIGLRFMA 209 Query: 196 VKDNPDAAESLGVVVFNSKMGAAAVSAFLVAVGGSFYAQFVSYIDPESVMGFQFSLLMAL 255 ++D+ + AESLG+ K+ A A+S+F + G+ + + PE + G LL+ L Sbjct: 210 LRDSEELAESLGINATKYKVLAFALSSFFAGIAGAMVVNYRVTVSPE-LYGVPLMLLIIL 268 Query: 256 PAVLGGIGTLWGPVLGAVILIP-----LTELTRSFIGGSGRGVDLIVYGTLIVVISLALP 310 AVLGG+GTL+GP+ GA+++ L ++ R+ S D IV L++ + + +P Sbjct: 269 SAVLGGLGTLYGPLAGAIVIYLAKNWWLGQIIRTL---SLPINDDIVLYALLIAVGILMP 325 Query: 311 RGLVSVFSLRK 321 GL + K Sbjct: 326 EGLYHKVKVNK 336 >SMc01950 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Sme Sinorhizobium meliloti Length = 461 Score = 120 bits (301), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 98/319 (30%), Positives = 158/319 (49%), Gaps = 26/319 (8%) Query: 21 VIAALVPLFVKDVYVQNIMVLTLMYAALSQSWNILSGYCGQISLGHALYFGLGAYTTALL 80 VI ALV + +V N + L+Y L+ NI+ G G + LG+ ++ +GAY+ ALL Sbjct: 119 VIVALVGVQGSLKWVDNFGIQILIYVMLAWGLNIVVGLAGLLDLGYVAFYAVGAYSYALL 178 Query: 81 FTKFGVLPWFGMLAGGAISALIAMALGYPCFRLRGHYFVIATIVIAEIALLLIQNW-DWA 139 + FG+ W + G ++A + LG+P RLRG Y I T+ EI L++ NW + Sbjct: 179 SSYFGLSFWVLLPIAGLLAACWGVVLGFPVLRLRGDYLAIVTLAFGEIIRLVLINWTEVT 238 Query: 140 GAALGIDIPVRGDSW-LKFQFTRS---------------KLPYFYFALALACIAWFVTWW 183 G+ + + +KF T+ K+ FY L LA + FVT Sbjct: 239 KGTFGVSGIAKATLFGIKFDATKDGFAAMMGLPMSSAYYKIFLFYLILGLALLTAFVTIR 298 Query: 184 LEDSKWGYWWRAVKDNPDAAESLGVVVFNSKMGAAAVSAFLVAVGGSFYAQFVSYIDPES 243 L G W A++++ A SLG+ +K+ A A A GSF+A ++ PES Sbjct: 299 LRRMPIGRAWEALREDEIACRSLGINTVTTKLTAFATGAMFGGFAGSFFAVRQGFVSPES 358 Query: 244 VMGFQFSLLMALPAVLGGIGTLWGPVLGAVILIPLTELTRSF-----IGGSGRGVDL--- 295 + + ++++A+ VLGG+G+L G + AV++I TE+ R I G +L Sbjct: 359 FVFLESAVILAI-VVLGGMGSLTGIAIAAVVMIGGTEILRELTFLKMIFGPTFTPELYRM 417 Query: 296 IVYGTLIVVISLALPRGLV 314 +++G +VV+ + PRG V Sbjct: 418 LIFGLAMVVVMVWKPRGFV 436