BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0241.0060.p (412 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC3489 [V] COG1680 Beta-lactamase class C and other penicillin b... 97 7e-20 mll6665 [V] COG1680 Beta-lactamase class C and other penicillin ... 72 3e-12 SMb21600 [V] COG1680 Beta-lactamase class C and other penicillin... 70 9e-12 YPO1224 [V] COG1680 Beta-lactamase class C and other penicillin ... 70 1e-11 Cgl2363 [V] COG1680 Beta-lactamase class C and other penicillin ... 67 1e-10 >CC3489 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 575 Score = 97.1 bits (240), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 108/347 (31%), Positives = 157/347 (45%), Gaps = 38/347 (10%) Query: 28 SPAQIVQQAAKKYLGISNAPGCCIAVYDEKSFGTKGYVYPKGLSGVAGSSPAPFSVTTDT 87 S A I Q A++ + G + V D + V GL G AG P V T Sbjct: 41 SDAAIRQILAQRVDVDHQSRGMVVGVIDARGR----RVIAHGLMG-AGGKP----VDGQT 91 Query: 88 VFEIGSVTKVFTSTLLAVAVKAGGPSLDDTIGPYLNLFSAKAVGTPVLDAIQLVQFATHT 147 +FEIGSVTK TS LLA V+ G L+D + +L V T AI L+ ATHT Sbjct: 92 LFEIGSVTKALTSLLLADMVRRGEVRLEDPVADHLP--PGTVVPTRNGKAITLIDLATHT 149 Query: 148 SGMPEQP-----GDGLTGYSEQLFADEPPSGELINWWNQYDTPPQGCWQYSNIGFVTLGF 202 SG+P P D L Y++ + + L ++ D G ++YSN+G LG Sbjct: 150 SGLPRLPTNMAMKDPLNPYAD--YTEAQLDAFLRDYVLTRDI--GGIYEYSNLGVGLLGR 205 Query: 203 AVTQMFAKDKGHNYNEILAEYVTGPLGMKQTGAVVNSSWKIAQGCIGHWSKSAEPPYQIV 262 A A G +Y +L + V PLGM T A+V S + A+ GH + + Sbjct: 206 A----LAYRAGGDYETVLRQRVLTPLGMSDT-AIVLSPAQAARFSSGHNAA-----LEAT 255 Query: 263 FDRNTPTGGTAFDLKTTGDDMIRFLAAQIAAPNGALGSQIALTQQNHGTFPVCGENTSVT 322 + P+ A L++T DD+++ AA++ + L + A+ Q PV G V Sbjct: 256 THWDLPSLAGAGALRSTADDLLKLTAAELGLVDTPL--KAAMADQLVPRRPVGG---GVE 310 Query: 323 MGLAWQITTDTQGHTVFTKNGATSRGGFEAIVIVVPELQCGVAVLSN 369 + L W + + +G V T +G T GF++ V + GV VLSN Sbjct: 311 VALGWHVWSTPEGGIV-THSGGTM--GFQSFVGFNRKTGLGVVVLSN 354 >mll6665 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Mlo Mesorhizobium loti Length = 554 Score = 72.0 bits (175), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 82/313 (26%), Positives = 124/313 (39%), Gaps = 45/313 (14%) Query: 81 FSVTTDTVFEIGSVTKVFTSTLLAVAVKAGGPSLDDTIGPYL------NLFSAKAVGTPV 134 F + DT F IGS+TK FT+ + + G LD + YL N F+ + G P Sbjct: 51 FVMGDDTCFRIGSITKTFTAVAVMQLAEKGLVDLDVDVSEYLPGFKPQNPFAGRE-GGPH 109 Query: 135 LDAIQLVQFATHTSGMPEQPGDGLTGYSEQLFADEPP----SGELINWWNQYDTPPQGCW 190 I L + +HT+G+ +P G L A PP EL + D P G Sbjct: 110 GAQISLRKLMSHTAGLVREPKSG-----HYLDAARPPLADTVAELATSTLKQD-PSLGQM 163 Query: 191 QYSNIGFVTLGFAVTQMFAKDKGHNYNEILAEYVTGPLGMKQTGAVVNSSWKIAQGCIGH 250 YSN G G + + K +Y E ++E + PLGM QT + + Sbjct: 164 HYSNAGIAVAGRVIETLTRK----SYAEYVSENILKPLGMDQTSSGLAPGIAERLAPADM 219 Query: 251 WSKSAEPPYQIVFDRNTPTGGTAFDLKTTGDDMIRFLAA-----------QIAAPNGALG 299 W+ + P VFD P G + +T DM R++ QI +P Sbjct: 220 WTLEGDSPAP-VFDLGGPPAGNIY---STTSDMARYVQCLLRGGFAPDGWQIVSPGSLRE 275 Query: 300 SQIALTQQNHGTFPVCGENTSVTMGLAWQITTDTQGHTVFTKNGATSRGGFEAIVIVVPE 359 + + ++ GE + T GL + + D G T GA G+ + +I++P Sbjct: 276 MWVPIGKR------ASGERVANTYGLCFGV-GDVDGWTSVGHGGAVY--GYSSQMILLPA 326 Query: 360 LQCGVAVLSNQYF 372 GV + S F Sbjct: 327 AGVGVLIFSTLDF 339 >SMb21600 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Sme Sinorhizobium meliloti Length = 396 Score = 70.1 bits (170), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 101/404 (25%), Positives = 167/404 (41%), Gaps = 84/404 (20%) Query: 30 AQIVQQAAKKYLGISNAPGCCIAVYDEKSFGTKGYVYPKGLSGVAGSSPAPFSVTTDTVF 89 A++V + + + PG IAV + K Y++ GL+ S + VT +T+F Sbjct: 35 ARLVDETIRPLMREHGVPGMAIAV----TVRGKKYIFNYGLA----SRESGQKVTDETMF 86 Query: 90 EIGSVTKVFTSTLLAVAVKAGGPSLDDTIGPYLNLFSAKAVGTPVLDAIQLVQFATHTS- 148 EIGSV+K FT+ L + A G +L D G YL A+ D I L+ T+T+ Sbjct: 87 EIGSVSKTFTAMLASYAEARGDLTLSDPAGKYL-----PALAGTRFDDISLLNLGTYTAG 141 Query: 149 GMPEQPGDGLTGYSEQLFADEPPSGELINWWNQYD-TPPQGCWQ-YSNIGFVTLGFAVTQ 206 G+P Q D +T +I+++ + T G + YSN G+ Sbjct: 142 GLPLQFPDSVTDQE-----------SMIDYYRDWRPTYAAGTHRLYSNPSIGLFGY---- 186 Query: 207 MFAKDKGHNYNEILAEYVTGPLGMKQTGAVV--NSSWKIAQGCIGHWSKSAEPPYQIVFD 264 + AK G + +++ + + G+ T V + + A G +SK+ +P I Sbjct: 187 LAAKSMGEPFADLMEKSIFPAFGLTSTFIAVPQDRADDYAYG----YSKAGKP---IRVT 239 Query: 265 RNTPTGGTAFDLKTTGDDMIRFLAAQIAAPNGALGSQIALTQQNHGTFPVCGENTSVTMG 324 R A+ +KTT D+IRF+ A I + A+ + G F V ++T G Sbjct: 240 RGV-LDSEAYGVKTTAADLIRFVEANIDGTGLDEPIRRAIAATHTGYFKVG----AMTQG 294 Query: 325 LAWQI----------------TTDTQGHTV--------------FTKNGATSRGGFEAIV 354 L W++ + H V K G+T+ GF A Sbjct: 295 LGWEMYPYPTKLDDLLAGNSSRMALEPHKVSKLVPPAAPQENLWINKTGSTN--GFGAYA 352 Query: 355 IVVPELQCGVAVLSNQYFDASGVHPAGIGPGRTALEIISQLHPG 398 VP + G+ +L+N+ + PA + + A +I+S L G Sbjct: 353 AFVPAERIGIVMLANRNYPI----PARV---KAAYQILSTLESG 389 >YPO1224 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ype Yersinia pestis Length = 388 Score = 69.7 bits (169), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 97/375 (25%), Positives = 153/375 (40%), Gaps = 52/375 (13%) Query: 9 VHLHRQEGEMSDQMIEATTSPAQIVQQAAKKYLGISNAPGCCIAVYDEKSFGTKGYVYPK 68 +H H ++ Q + TS QIV Q A+ S A G + V D + + + Sbjct: 23 LHSHADTQPLTSQDTKLLTS--QIVDQYAEHIFYNSGAVGMALVVIDNNQVVNRSFGETQ 80 Query: 69 GLSGVAGSSPAPFSVTTDTVFEIGSVTKVFTSTLLAVAVKAGGPSLDDTIGPYLNLFSAK 128 + + P P D++ I S+TK+ TS ++ G L D + Y + K Sbjct: 81 PGNNI---RPRP-----DSLIRIASITKLMTSEIMVKLADDGIVKLTDPLKKY----APK 128 Query: 129 AVGTPVLDA---IQLVQFATHTSGMP-EQPGDGLTGYSEQLFADEPPSGELINWWN--QY 182 V P A I+L+ A+HTSG+P EQPG G ++ P W + Sbjct: 129 GVNVPSYSAKQPIRLLHLASHTSGLPREQPG----GPQKRPVFTWPTKDNRWQWLKLAKV 184 Query: 183 DTPPQGCWQYSNIGFVTLGFAVTQMFAKDKGHNYNEILAEYVTGPLGMKQTGAVVNSSWK 242 PP YSN+ + L A++ + G Y +L + +T PLGMK T + ++ + Sbjct: 185 TVPPGVKAAYSNLAYDLLADALS----RAAGKPYAHLLRDKITAPLGMKNT-TLTPTAEQ 239 Query: 243 IAQGCIGHWSKSAEPPYQIVFDRNTPTGGTAFDLKTTGDD----MIRFLAAQIAAPNGAL 298 + IG S NT + + +T +D M +FLA+ +AP + Sbjct: 240 CKRLMIGVGSSRCG---------NTVAAAGSGGIYSTPEDMQHWMQQFLASDNSAPKRSA 290 Query: 299 GSQIALTQQNHGTFPVCGENT---SVTMGLAWQI---TTDTQGHTVFTKNGATSRGGFEA 352 + AL Q + G + + +GL W D G + K G GGF Sbjct: 291 KREQALYFQRGDLVSLKGMDVAGQADALGLGWVYMAPKADLPG--IMQKTGGG--GGFIT 346 Query: 353 IVIVVPELQCGVAVL 367 + +VPE GV V+ Sbjct: 347 YMAMVPEKNIGVFVV 361 >Cgl2363 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Cgl Corynebacterium glutamicum Length = 342 Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 54/205 (26%), Positives = 89/205 (43%), Gaps = 18/205 (8%) Query: 86 DTVFEIGSVTKVFTSTLLAVAVKAGGPSLDDTIGPYLNLFSAKAVGTPVLDAIQLVQFAT 145 D FEI S+TK+FT LL + ++ G + +G L + V ++ I + + A Sbjct: 77 DDPFEIASITKIFTGELLRLQIERGEITESTAVGDVL----GERVADSLIRDITVEELAN 132 Query: 146 HTSGMPEQPGDGLTGYSEQLFADEP----PSGELINWWNQYDTPPQGCWQYSNIGFVTLG 201 HTSG+P GL + F P + +I+ +G + YSN+GF LG Sbjct: 133 HTSGLPRLGNVGLRPFMATFFDKNPYKDLSADRVISISTTSKLNSRGEFHYSNLGFALLG 192 Query: 202 FAVTQMFAKDKGHNYNEILAEYVTGPLGMKQTGAVVNSSWKIAQGCIGHWSKSAEPPYQI 261 Q+ A++ G ++++L + PL + T + S +AQ +S + Sbjct: 193 ----QVLARNAGLTFDQLLDRDLLAPLNLNNTKLMTPES--LAQDAPQGFSTPGKQVEAW 246 Query: 262 VFDRNTPTGGTAFDLKTTGDDMIRF 286 D P G L++T DM F Sbjct: 247 EMDGFLPAAG----LRSTARDMAVF 267