BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0236.0003.p (304 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr0545 [GER] COG0697 Permeases of the drug/metabolite transport... 312 7e-85 AGc3116 [GER] COG0697 Permeases of the drug/metabolite transport... 280 2e-75 SMc00197 [GER] COG0697 Permeases of the drug/metabolite transpor... 280 4e-75 SMb20705 [GER] COG0697 Permeases of the drug/metabolite transpor... 125 1e-28 AGc357 [GER] COG0697 Permeases of the drug/metabolite transporte... 123 5e-28 >mlr0545 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 337 Score = 312 bits (799), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 167/306 (54%), Positives = 221/306 (72%), Gaps = 2/306 (0%) Query: 1 LTLSSNLRGSLFMAAAMASFTVNDTITKAVSAELNIGEILLVRGLVAMVLVAALAWYRDA 60 L LS NLRG+LFM AM FT+ND ITK S +N+ +++L+RG A + V LAW R A Sbjct: 32 LPLSPNLRGALFMMVAMVGFTLNDAITKYSSQSMNMAQVMLIRGAFASLFVGLLAWQRGA 91 Query: 61 LRSFRALLIWPVGLRVLGEIGGTLTYLSAISQIPLANASAIFQALPLVITLGAALVFGEP 120 L +L V +RVLGE G T+++L A++ +P+ + SA+ QALPL +T+GAAL FGE Sbjct: 92 LLRPGLMLQPLVAMRVLGEAGATVSFLVALAHLPIGSVSAVLQALPLAVTMGAALFFGEA 151 Query: 121 VGWRRWLAISAGFIGVLVIVRPGAEGFSQAALLALASVGFCAVRDLATRRIPKDLPTVFI 180 VGWRRWLAI+AGF GV+VIVRPG +GF+ +L ALASV C VRDLATRRIP+ PT+ + Sbjct: 152 VGWRRWLAIAAGFAGVMVIVRPGFDGFTIYSLWALASVACCTVRDLATRRIPQTTPTMLV 211 Query: 181 TLLTTVTVTTAGAVVLVPLGGWRPLSGNALGLLTFAAVLILIGYQCIIVSLRTGDISAVA 240 + T + +T GAV+LVP+GGW P++G + LL AAVL+LIGYQ II+++R+G+IS +A Sbjct: 212 STATALAMTVVGAVLLVPMGGWTPMTGKSTALLALAAVLVLIGYQFIIMAMRSGEISFIA 271 Query: 241 PFRYTALPWAMLTGYLAFGHKPDGPMLAGAAIIVASGLYAFYRER--KRDKLRPAATGPG 298 PFRYTAL W++L G + FG PD PM+ GA I+V SGLYA YRER R ++ TGP Sbjct: 272 PFRYTALLWSILLGLIVFGDIPDMPMVVGATIVVGSGLYALYRERVVGRRRIVAETTGPA 331 Query: 299 LPPDGL 304 + PDG+ Sbjct: 332 MAPDGI 337 >AGc3116 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 357 Score = 280 bits (717), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 146/292 (50%), Positives = 201/292 (68%), Gaps = 2/292 (0%) Query: 1 LTLSSNLRGSLFMAAAMASFTVNDTITKAVSAELNIGEILLVRGLVAMVLVAALAWYRDA 60 + L+ N RG+LFMA AMASFT ND +TK+V+ +N G+I+ VRG++ +VL+ A + A Sbjct: 36 MALTDNTRGALFMALAMASFTANDALTKSVTPYINTGQIMFVRGVMTVVLIYIAARHFGA 95 Query: 61 LRSFRALLIWPVGLRVLGEIGGTLTYLSAISQIPLANASAIFQALPLVITLGAALVFGEP 120 LR + LL + LR L E+ + YL+A+ I +NASAI Q+LPLV+TLGAAL EP Sbjct: 96 LRPLKTLLRPIIILRCLCEVTAAVLYLTALGLIEFSNASAILQSLPLVVTLGAALFLREP 155 Query: 121 VGWRRWLAISAGFIGVLVIVRPGAEGFSQAALLALASVGFCAVRDLATRRIPKDLPTVFI 180 VGWRRW+AI GFIGVLVI+RPG EGF+ ALL +AS+ A RDL TR++ D+P++ I Sbjct: 156 VGWRRWVAIIVGFIGVLVIIRPGPEGFTPGALLVVASLAVTAARDLLTRKMYADVPSLAI 215 Query: 181 TLLTTVTVTTAGAVVLVPLGGWRPLSGNALGLLTFAAVLILIGYQCIIVSLRTGDISAVA 240 T++T G +++VP GGW+P++ + L +A+L+L+GYQ II+S+RTG+IS VA Sbjct: 216 TVITAFVNMAVGGLLIVPFGGWQPMNFTIVSHLAGSAILVLVGYQAIILSMRTGEISFVA 275 Query: 241 PFRYTALPWAMLTGYLAFGHKPDGPMLAGAAIIVASGLYAFYRE--RKRDKL 290 PFRYT L W + G F K D + GA I++ SGLY FYRE RKR ++ Sbjct: 276 PFRYTGLLWGFMIGVFFFNEKIDSYTIIGAMIVIGSGLYTFYRESLRKRSQM 327 >SMc00197 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 302 Score = 280 bits (715), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 146/299 (48%), Positives = 203/299 (67%) Query: 4 SSNLRGSLFMAAAMASFTVNDTITKAVSAELNIGEILLVRGLVAMVLVAALAWYRDALRS 63 S+N RG +FM AM F ND + K+V+ +N G+I+ +RGL+ ++V +A+ A R Sbjct: 4 SANFRGIVFMCLAMIGFACNDALVKSVTGAMNTGQIMFMRGLLTTLMVVVVAYRFGAFRP 63 Query: 64 FRALLIWPVGLRVLGEIGGTLTYLSAISQIPLANASAIFQALPLVITLGAALVFGEPVGW 123 R + + LR+ E ++TY+SA+ QIPLANASAI QALPL +TLGAAL GEPVGW Sbjct: 64 VRTIFRPAILLRIAMEALASVTYISALGQIPLANASAIMQALPLAVTLGAALFLGEPVGW 123 Query: 124 RRWLAISAGFIGVLVIVRPGAEGFSQAALLALASVGFCAVRDLATRRIPKDLPTVFITLL 183 RRW AI GF GVL+++RPG EGF+ AAL +A V A RDL TRRI D+P+++IT+ Sbjct: 124 RRWAAIVVGFAGVLIVLRPGPEGFTAAALTVVACVFCTATRDLCTRRIGTDVPSLYITVT 183 Query: 184 TTVTVTTAGAVVLVPLGGWRPLSGNALGLLTFAAVLILIGYQCIIVSLRTGDISAVAPFR 243 T++ T GA ++VPLGGW+P+S +L + A+VL+++GYQ I++++R G+IS +APFR Sbjct: 184 TSLVTTLVGAALIVPLGGWQPMSATSLSHIAGASVLLMLGYQTIVLAMREGEISVIAPFR 243 Query: 244 YTALPWAMLTGYLAFGHKPDGPMLAGAAIIVASGLYAFYRERKRDKLRPAATGPGLPPD 302 Y +L W++ G + F PD MLAG AII+ SGLY FYRE KR + A G P + Sbjct: 244 YMSLLWSVTLGVVFFAETPDRWMLAGVAIIIGSGLYTFYRESKRGRQAVAQRALGGPLE 302 >SMb20705 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 303 Score = 125 bits (314), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 92/285 (32%), Positives = 150/285 (52%), Gaps = 11/285 (3%) Query: 9 GSLFMAAAMASFTVNDTITKAVSAELNIGEILLVRGLVAMVLVAALAWYRDALRSFRALL 68 G + M M F+VND + K + A ++G+++L+R + A +L+A W + F L Sbjct: 20 GVVVMLLGMLMFSVNDVMGKWLVATYSVGQVVLIRSIAAALLLAPFLWVSGPKKLFT--L 77 Query: 69 IWPVGL---RVLGEIGGTLTYLSAISQIPLANASAIFQALPLVITLGAALVFGEPVGWRR 125 P GL RV+ + + A+ +PLA+ + A P+ + + LV EPVGWRR Sbjct: 78 ERP-GLQLARVVASTAEVVAFYFAVVYLPLADVMTYWLAAPIYVAAVSPLVLKEPVGWRR 136 Query: 126 WLAISAGFIGVLVIVRPGAEGFSQAALLA-LASVGFCAVRDLATRRIPKDLPTVFITLLT 184 W AI GF+GV+V + P ++ F+ A+++ L S+ F + + + R + P + Sbjct: 137 WTAIGIGFVGVVVALEPSSQAFTLPAVISILGSMTFAFM--MISGRSLRGTPDTTLAFWQ 194 Query: 185 TVTVTTAGAVVLVPLGGWRPLSGNALGLLTFAAVLILIGYQCIIVSLRTGDISAVAPFRY 244 V AG +V P W PL L+ + +I + + +L+ D + VAP +Y Sbjct: 195 IVGAAVAG-LVWAPFD-WTPLKPLDTALICLLGAVAMIAHVLVNRALKLADAATVAPLQY 252 Query: 245 TALPWAMLTGYLAFGHKPDGPMLAGAAIIVASGLYAFYRERKRDK 289 T L WA+ G+L FG P M+ GAA+IVASGL+ F+RE++ + Sbjct: 253 TLLFWAIFFGWLIFGDTPRLSMVIGAALIVASGLFIFFREQQLKR 297 >AGc357 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 328 Score = 123 bits (309), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 88/288 (30%), Positives = 147/288 (51%), Gaps = 11/288 (3%) Query: 13 MAAAMASFTVNDTITKAVSAELNIGEILLVRGLVAMVLVAALAWYRDALRSFRALLIWPV 72 M M F +ND + K + + + G+++L+R A+V++ + W R L + + Sbjct: 38 MLLGMLLFALNDAMGKWLVSTYSQGQVILIRSAAALVILVPIVW-RAGLSGL--VNVERP 94 Query: 73 GL---RVLGEIGGTLTYLSAISQIPLANASAIFQALPLVITLGAALVFGEPVGWRRWLAI 129 GL RV + A++ +PLA+ + A P+ + A + GE VGWRRW AI Sbjct: 95 GLQVARVFFSTAELFCFYFAVASLPLADVMTYWLAAPIYVAALAPFLLGEKVGWRRWTAI 154 Query: 130 SAGFIGVLVIVRPGAEGFSQAALLALASVGFCAVRDLATRRIPKDLPTVFITLLTTVTVT 189 + GF+GVL+ ++P + + AAL ++ A L+ R++ ++ P + + Sbjct: 155 AIGFVGVLIALKPSSASLTSAALFSILGSAAFAFMMLSGRQL-RNTPDTVLAFWQIIGAG 213 Query: 190 TAG--AVVLVPLGGWRPL-SGNALGLLTFAAVLILIGYQCIIVSLRTGDISAVAPFRYTA 246 AG AV + P GW P+ S L L+ V+ + + + +L+ D + VAP +YT Sbjct: 214 LAGIVAVFMTP-SGWLPVQSSFDLAFLSLLGVVAMAAHVLVNRALKLADAATVAPLQYTL 272 Query: 247 LPWAMLTGYLAFGHKPDGPMLAGAAIIVASGLYAFYRERKRDKLRPAA 294 L WA++ G+L F P ++ GA +IV SGLY F+RE + R AA Sbjct: 273 LLWAVIFGWLFFNDVPQTSIVVGAGLIVFSGLYIFFRENTLKRRRDAA 320