BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0230.0008.p (1373 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5779 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 1054 0.0 RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1023 0.0 PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1019 0.0 RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1015 0.0 YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1003 0.0 >mll5779 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1038 Score = 1054 bits (2725), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/1041 (53%), Positives = 740/1041 (71%), Gaps = 8/1041 (0%) Query: 335 MSISQGFIRKPVATAFLAIGITLIGLVAFVRLPVSALPSVDTPTIQVTAQLPGADPQTMG 394 MS+S F+++P+AT L +GI L+G+VA++ LP+S+LP VD PTI V + LPGA +TM Sbjct: 1 MSVSNIFVQRPIATGLLTLGIVLVGMVAYMLLPISSLPQVDFPTIAVESTLPGAKAETMA 60 Query: 395 SSVATPLERQFGQIAGLTAMTSSSGFGNTAITLQFALNRTTDAAAQDVQAAINAAAGQLP 454 S+VA+PLE+QF I GL MTS+S G T +TLQF L+R D+AAQDVQAAINAA+G LP Sbjct: 61 STVASPLEQQFSTIPGLAQMTSTSTLGKTDMTLQFDLSRNIDSAAQDVQAAINAASGSLP 120 Query: 455 KTMPSPPIFRKVNPADVPVLLIALTSDTEPLTKVDDYADSILAQKLSQVPGVSLVTIGGM 514 K M SPP + KVNPA V+ I L SDT PL V D A +++AQ LSQ+PG V + G Sbjct: 121 KAMQSPPTYHKVNPALFTVISIVLQSDTIPLPLVMDAASNMVAQTLSQIPGAGFVDMPGS 180 Query: 515 QKPSIRVQVNPAKLAAAGIDLEQLRSTLGNITVNQPKGVLYGNEQAYTLATNDQVLSAKG 574 K +IR+Q++P KLA+ G+ LE +RS L T N PKG L G +++ TL N+Q+L++ Sbjct: 181 SKSAIRIQLDPMKLASLGMSLEDVRSALVVGTTNGPKGTLEGAQRSVTLDANNQLLTSAD 240 Query: 575 YEDLIIAYRNGAPVRLRDIGHAEVAAEDVTLHGWYNDKPSVILAIQRQPGANVISTVDGI 634 IIAYRNG+P+R+ DIG A + E+ TL WYN++ +V++ + Q GAN + V+G+ Sbjct: 241 ASAAIIAYRNGSPIRISDIGRAIDSVENTTLGAWYNNRKAVLIDVHLQSGANAVDVVNGV 300 Query: 635 KKLLPQLVAGLPSDVKVTIASDRTQTIRASVDDVQFTLLLTIALVVGVIFLFLRNFWATM 694 K LP L LP V++ A D T +RA+V DVQFTL++TI LVV IFLFL++ AT+ Sbjct: 301 KAALPGLRLRLPPSVQIMTAGDSTVAVRAAVADVQFTLMITIGLVVLTIFLFLKSMSATI 360 Query: 695 IPAISVPISLIGTFGVMYLLNYSLDNLSLMGLSIAVGFVVDDAIVMIENISRHIEEGLSP 754 IPA+++P+SLIGTFGVMYLL YSLDN+SLMGL+IAVGFVVDDAIV+IENI RHIE G SP Sbjct: 361 IPAVTIPVSLIGTFGVMYLLGYSLDNISLMGLTIAVGFVVDDAIVVIENIVRHIEGGESP 420 Query: 755 LEAALKGAGEIGFTIISISVSLVAVFIPLLLMGGVIGRMFQEFAVTVCVAIAVSVIVSVT 814 LEA LKGA EIGFT++S++ SL+AVFIPLLLM ++GR+F+EF+VT+ VA+ +S +VS+T Sbjct: 421 LEATLKGASEIGFTVVSMTASLIAVFIPLLLMSSMVGRLFREFSVTIAVALIISALVSLT 480 Query: 815 LTPMMCAYLLSDHG--AGTGVVSRTLERGFVAIQRGYEAVLSVALRFKLATLTVMLASIV 872 LTPMMCA ++ HG A +S LERGF IQRGY L V + L A++ Sbjct: 481 LTPMMCALMIKGHGHEAKPNRLSSLLERGFDFIQRGYSRSLRVVVGHPRLVLLCFFATLA 540 Query: 873 ATGALFAGIPKGFFPQQDTGMITGITEASADVSPTEMAELQRSAIDVIAKDPSVANATGY 932 T LF IPKGFFPQQD G+I+G T+A+ D+S MA Q++ +D+I KDP+V Sbjct: 541 VTAELFLAIPKGFFPQQDLGLISGSTQAAQDISFQAMAAKQQAVVDLILKDPAVDTVRST 600 Query: 933 IGPGGPTVTENNGRLFVLLKPRNERQFSADEVIRQLDAKLAKLQGIAVFMQATQDINLAS 992 +G G N+G L ++LKP +ER SAD+VI +L + A + G++V MQA Q IN+ + Sbjct: 601 LGGSG---RMNSGNLQIVLKPLSERSVSADQVIARLRKETAGVSGVSVGMQAVQGINVGA 657 Query: 993 RLSKTQYQFTLTDVNQDELNSWAGKLFEALKKRPELADVASDQANAARQLKLKIDRDAAS 1052 R S+TQ+Q+TL D N EL WA + L+K P++ DVA+D A + +DRD AS Sbjct: 658 RGSQTQFQYTLQDPNLPELYRWADTMTAELRKLPQVRDVANDLQAVAPHASIAVDRDTAS 717 Query: 1053 RLGIDPAAVDNTLYDAFGQRHVAQLFTTLNTYYVILEVDPSFQSGPYALNRIYVRSSNGS 1112 RLGI P A+D+TLYDAFGQR V +FT + + +++E+DP ++ AL+ IYV S++G Sbjct: 718 RLGITPQAIDDTLYDAFGQRQVTTIFTQADQHKIVMEIDPKYRVDAGALDAIYVGSNSGK 777 Query: 1113 MVPLSQFTTIEYGSAALAGNHQNQFPSVTLSFNLAPGTAVGTAVAAVQQETAALHMPSTI 1172 VPLS F + A L NHQ FPSVTLSFNLAP A+G AV AV+ A + M +T+ Sbjct: 778 QVPLSAFAKVSSSVAPLTINHQGLFPSVTLSFNLAPNVALGDAVTAVEAMQARIRMSATV 837 Query: 1173 ATSFQGNAQAFQSALASTPVLILAAIVAVYLILGMLYESTIHPITILSTLPSAGLGALMA 1232 T FQG AQAFQ++L++ P+LI+AA++AVY++LGMLYES IHPITILSTLPSAG+GAL Sbjct: 838 QTGFQGTAQAFQASLSTQPMLIVAALIAVYIVLGMLYESVIHPITILSTLPSAGVGALAT 897 Query: 1233 LWTFGFGLDVIGLIGIILLIGLVQKNGIMLIDFALEAERHRGLSAEQSALEACKVRFRPI 1292 L G LDV+GL+GIILLIG+V+KN IM+IDFAL AER RGL +++ ++AC +RFRPI Sbjct: 898 LMLVGGQLDVMGLVGIILLIGIVKKNAIMMIDFALSAERDRGLPPKEAIIQACILRFRPI 957 Query: 1293 LMTTMCAMLGGVPLIIGTGTGSELRQPLGFAIVGGLIVSQLLTLFTTPVVYIYLQNVSDW 1352 MTT+CA+LG +PL +GTG GSELR+PLG AIVGGL VSQLLTL+TTPV+Y+Y+Q + Sbjct: 958 TMTTLCALLGALPLALGTGVGSELRRPLGIAIVGGLCVSQLLTLYTTPVIYLYMQQFAGL 1017 Query: 1353 FAG--QRTADRSP-LPATKPE 1370 G R R P LPA E Sbjct: 1018 MMGVKYRIIGRRPALPAVPAE 1038 >RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1041 Score = 1023 bits (2645), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/1046 (52%), Positives = 730/1046 (69%), Gaps = 27/1046 (2%) Query: 335 MSISQGFIRKPVATAFLAIGITLIGLVAFVRLPVSALPSVDTPTIQVTAQLPGADPQTMG 394 M+ S+ FI +PVAT L + I L GLVA+ LP+SALP VD PTIQVT PGA P M Sbjct: 1 MNPSRIFILRPVATTLLMVAILLSGLVAYRMLPLSALPEVDYPTIQVTTLYPGASPDVMT 60 Query: 395 SSVATPLERQFGQIAGLTAMTSSSGFGNTAITLQFALNRTTDAAAQDVQAAINAAAGQLP 454 SS+ PLERQFGQ+ GL MTS+S G + ITLQF L+ + D A Q+VQAAINAA LP Sbjct: 61 SSITAPLERQFGQMPGLKQMTSASSGGASVITLQFDLSLSLDIAEQEVQAAINAAGNLLP 120 Query: 455 KTMPSPPIFRKVNPADVPVLLIALTSDTEPLTKVDDYADSILAQKLSQVPGVSLVTIGGM 514 +P PPI+ KVNPAD P+L +A+TS T PL K++D D+ +AQKLSQ+PG+ LV+I G Sbjct: 121 TDLPMPPIYSKVNPADAPILTLAITSRTLPLPKLEDIVDTRVAQKLSQLPGIGLVSISGG 180 Query: 515 QKPSIRVQVNPAKLAAAGIDLEQLRSTLGNITVNQPKGVLYGNEQAYTLATNDQVLSAKG 574 Q+P++R+Q N LAA G+ ++ +R+ +GN VN KG G +A T+ NDQ+ SA Sbjct: 181 QRPAVRIQANTQALAALGLSIDDIRTAIGNANVNGAKGSFDGPMRASTIDANDQLRSAAE 240 Query: 575 YEDLIIAYRNGAPVRLRDIGHAEVAAEDVTLHGWYNDKPSVILAIQRQPGANVISTVDGI 634 Y +I+AY+NGAP+RL D+ AE+ L W N P++IL +QRQPGANVI V+ Sbjct: 241 YGTMIVAYKNGAPIRLTDVAQIIDGAENSKLAAWANTTPAIILNVQRQPGANVIDVVNRA 300 Query: 635 KKLLPQLVAGLPSDVKVTIASDRTQTIRASVDDVQFTLLLTIALVVGVIFLFLRNFWATM 694 K LLPQL LP+++ V + +DRT TIRASV DVQF LLL +ALVV VIFLFLRN AT+ Sbjct: 301 KALLPQLKDTLPANIDVAVLTDRTTTIRASVADVQFELLLAVALVVMVIFLFLRNIPATI 360 Query: 695 IPAISVPISLIGTFGVMYLLNYSLDNLSLMGLSIAVGFVVDDAIVMIENISRHIEEGLSP 754 IPA++VP+SL+GTFGVMYL +S++NL+LM L+IA GFVVDDAIVMIENI+R+IE+G P Sbjct: 361 IPAVAVPLSLVGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMIENIARYIEDGDPP 420 Query: 755 LEAALKGAGEIGFTIISISVSLVAVFIPLLLMGGVIGRMFQEFAVTVCVAIAVSVIVSVT 814 +EAALKGA +IGFTIIS++ SL+AV IPLL M V+GR+F+EFA+T+ V+I +S +VS+T Sbjct: 421 MEAALKGARQIGFTIISLTFSLIAVLIPLLFMSDVVGRLFREFAITLAVSILISAVVSLT 480 Query: 815 LTPMMCAYLLSD----------HGAGTGVVSRTLERGFVAIQRGYEAVLSVALRFKLATL 864 LTPMMCA LL H AG + F + Y +L L + TL Sbjct: 481 LTPMMCARLLRHIPEPEQTRFYHAAG---------QFFDNVIAQYGRMLQWVLDRQRTTL 531 Query: 865 TVMLASIVATGALFAGIPKGFFPQQDTGMITGITEASADVSPTEMAELQRSAIDVIAKDP 924 V + ++ TG L+ +PKGFFP QDTG+I GI++A+ +S MAE Q+ +VI KDP Sbjct: 532 LVAIGTLALTGLLYVYVPKGFFPVQDTGVIQGISDATQSISFPAMAERQQKLAEVILKDP 591 Query: 925 SVANATGYIGPGGPTVTENNGRLFVLLKPRNERQFSADEVIRQLDAKLAKLQGIAVFMQA 984 +V + + +IG G T N+GR+ + LKP++ R A E+I++L +LAK+ GI++FMQ Sbjct: 592 AVESLSSFIGVDGTNTTLNSGRMLINLKPKDARDADATEIIQRLQPELAKVGGISLFMQP 651 Query: 985 TQDINLASRLSKTQYQFTLTDVNQDELNSWAGKLFEALKKRPELADVASDQANAARQLKL 1044 QD+ + R+S+TQYQFT+ D + + L+ W +L E L++ EL DVASD + + + Sbjct: 652 VQDLTIEDRVSRTQYQFTVEDPDPNNLSKWVPRLVERLQQTGELRDVASDLQDNGLRAYV 711 Query: 1045 KIDRDAASRLGIDPAAVDNTLYDAFGQRHVAQLFTTLNTYYVILEVDPSFQSGPYALNRI 1104 +IDRD A+ G+ AAVD+ LY A+GQR ++ +FT N Y V+LE P Q GP +L + Sbjct: 712 QIDRDKAAVYGVTTAAVDSALYSAYGQRLISTIFTQSNQYRVVLEAAPQLQKGPQSLYDL 771 Query: 1105 YVRSSNGSMVPLSQFTTIEYGSAALAGNHQNQFPSVTLSFNLAPGTAVGTAVAAVQQETA 1164 V S+ G VPL F T+ +L NHQ QFPS T+SFNLA G ++G AV A+ Sbjct: 772 RVASTGGQQVPLGAFATVVEQPGSLVVNHQGQFPSATISFNLARGASLGAAVDAINAAEQ 831 Query: 1165 ALHMPSTIATSFQGNAQAFQSALASTPVLILAAIVAVYLILGMLYESTIHPITILSTLPS 1224 A+ +P+++ TSFQG A AFQS+L++ LILAAI+ +Y++LG+LYESTIHP+TILSTLPS Sbjct: 832 AIGLPASMQTSFQGAALAFQSSLSNELWLILAAIITMYIVLGVLYESTIHPVTILSTLPS 891 Query: 1225 AGLGALMALWTFGFGLDVIGLIGIILLIGLVQKNGIMLIDFALEAERHRGLSAEQSALEA 1284 AG+GAL++L G + +I +IGIILLIG+V+KN IM+IDFALEAER +G++ + +A Sbjct: 892 AGVGALLSLLVSGKDMGIIAIIGIILLIGIVKKNAIMMIDFALEAEREQGMAPRDAIYQA 951 Query: 1285 CKVRFRPILMTTMCAMLGGVPLIIGTGTGSELRQPLGFAIVGGLIVSQLLTLFTTPVVYI 1344 C +RFRPILMTTM A+LG +PL++GTG GSELRQPLG +VGGL+VSQ+LTLFTTPV+Y+ Sbjct: 952 CLLRFRPILMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYL 1011 Query: 1345 YL----QNVSDW---FAGQRT-ADRS 1362 + DW A +RT AD+S Sbjct: 1012 AFDSLGHRLRDWRERRAARRTGADQS 1037 >PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1043 Score = 1019 bits (2634), Expect = 0.0, Method: Compositional matrix adjust. Identities = 546/1024 (53%), Positives = 724/1024 (70%), Gaps = 1/1024 (0%) Query: 335 MSISQGFIRKPVATAFLAIGITLIGLVAFVRLPVSALPSVDTPTIQVTAQLPGADPQTMG 394 M+ S+ FI +PVAT L + I L GL+A+ LP+SALP VD PTIQV PGA P+ M Sbjct: 1 MNPSRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMT 60 Query: 395 SSVATPLERQFGQIAGLTAMTSSSGFGNTAITLQFALNRTTDAAAQDVQAAINAAAGQLP 454 SS+ PLE Q GQI GL M+SSS G + ITLQF+L D A Q+VQAAINAA LP Sbjct: 61 SSITAPLENQLGQIPGLNEMSSSSSGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLP 120 Query: 455 KTMPSPPIFRKVNPADVPVLLIALTSDTEPLTKVDDYADSILAQKLSQVPGVSLVTIGGM 514 +P+ P+F KVNPAD P+L +A+ SD PL ++ D D+ LAQK+SQ+ GV LV+I G Sbjct: 121 NDLPNQPVFSKVNPADAPILTLAVMSDGMPLPQIQDLVDTRLAQKISQISGVGLVSISGG 180 Query: 515 QKPSIRVQVNPAKLAAAGIDLEQLRSTLGNITVNQPKGVLYGNEQAYTLATNDQVLSAKG 574 Q+P++RV+ NP LAAAG+ LE LRST+ + +N PKG G +A TL NDQ+ SA Sbjct: 181 QRPAVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRASTLDANDQLRSADA 240 Query: 575 YEDLIIAYRNGAPVRLRDIGHAEVAAEDVTLHGWYNDKPSVILAIQRQPGANVISTVDGI 634 Y DLIIAY+NG+P+R+RD+ E AE+V L W N+ P+V+L IQRQPGANVI VD I Sbjct: 241 YRDLIIAYKNGSPLRIRDVASVEDDAENVRLAAWANNLPAVVLNIQRQPGANVIEVVDRI 300 Query: 635 KKLLPQLVAGLPSDVKVTIASDRTQTIRASVDDVQFTLLLTIALVVGVIFLFLRNFWATM 694 K LLPQL + LP ++ V + +DRT TIRASV DVQF L L +ALVV V FLFLRN +AT+ Sbjct: 301 KALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFLFLRNVYATL 360 Query: 695 IPAISVPISLIGTFGVMYLLNYSLDNLSLMGLSIAVGFVVDDAIVMIENISRHIEEGLSP 754 IP+ +VP+SLIGTFGVMYL +S++NL+LM L+IA GFVVDDAIVM+ENI+R++E+G SP Sbjct: 361 IPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIARYLEQGDSP 420 Query: 755 LEAALKGAGEIGFTIISISVSLVAVFIPLLLMGGVIGRMFQEFAVTVCVAIAVSVIVSVT 814 LEAALKG+ +IGFTIIS++ SL+AV IPLL MG V GR+F+EFA+T+ VAI +S VS+T Sbjct: 421 LEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAILISGFVSLT 480 Query: 815 LTPMMCAYLLSDHGAG-TGVVSRTLERGFVAIQRGYEAVLSVALRFKLATLTVMLASIVA 873 LTPM+ A LL G +R R + Y L V LR + TL V +A++ Sbjct: 481 LTPMLSAKLLRHIDEDQQGRFARAAGRVIDGLIAQYAKALRVVLRHQPLTLLVAIATLAL 540 Query: 874 TGALFAGIPKGFFPQQDTGMITGITEASADVSPTEMAELQRSAIDVIAKDPSVANATGYI 933 T L+ +PKGFFP QDTG+I G+ EA +S M+E QR+ +V+ KDP+VA+ + YI Sbjct: 541 TALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLKDPAVASLSSYI 600 Query: 934 GPGGPTVTENNGRLFVLLKPRNERQFSADEVIRQLDAKLAKLQGIAVFMQATQDINLASR 993 G G T N GRL + LKP +ER +A EVI++L +L L GI ++MQ QD+ + R Sbjct: 601 GVDGSNPTLNTGRLLINLKPHSERDVTASEVIQRLQPELDHLPGIKLYMQPVQDLTIEDR 660 Query: 994 LSKTQYQFTLTDVNQDELNSWAGKLFEALKKRPELADVASDQANAARQLKLKIDRDAASR 1053 +++TQYQFTL D + D L W KL L++ P+LADVASD + Q L IDRD ASR Sbjct: 661 VARTQYQFTLQDADPDVLAEWVPKLVARLQELPQLADVASDWQDKGLQAYLNIDRDTASR 720 Query: 1054 LGIDPAAVDNTLYDAFGQRHVAQLFTTLNTYYVILEVDPSFQSGPYALNRIYVRSSNGSM 1113 LG+ + +D+ LY+AFGQR ++ +FT Y V+LEV P FQ GP AL ++YV SS+G+ Sbjct: 721 LGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQFQLGPQALEQLYVPSSDGTQ 780 Query: 1114 VPLSQFTTIEYGSAALAGNHQNQFPSVTLSFNLAPGTAVGTAVAAVQQETAALHMPSTIA 1173 V LS +E LA NH QFPS TLSFNLA G ++G AV A++ A+L +P ++ Sbjct: 781 VRLSSLAKVEERHTLLAINHIAQFPSATLSFNLAKGYSLGEAVEAIRGVEASLELPLSMQ 840 Query: 1174 TSFQGNAQAFQSALASTPVLILAAIVAVYLILGMLYESTIHPITILSTLPSAGLGALMAL 1233 SF+G A AF+++L++T +LILA++V +Y++LG+LYES IHP+TILSTLPSAG+GAL+AL Sbjct: 841 GSFRGAALAFEASLSNTLLLILASVVTMYIVLGILYESFIHPVTILSTLPSAGVGALLAL 900 Query: 1234 WTFGFGLDVIGLIGIILLIGLVQKNGIMLIDFALEAERHRGLSAEQSALEACKVRFRPIL 1293 G + ++ +IGIILLIG+V+KN IM+IDFAL+AER+ G ++ +AC +RFRPIL Sbjct: 901 MLAGQEIGIVAIIGIILLIGIVKKNAIMMIDFALDAERNEGKPPHEAIYQACLLRFRPIL 960 Query: 1294 MTTMCAMLGGVPLIIGTGTGSELRQPLGFAIVGGLIVSQLLTLFTTPVVYIYLQNVSDWF 1353 MTTM A+LG +PL++ G G+ELRQPLG +VGGL++SQ+LTLFTTPV+Y+Y ++ + Sbjct: 961 MTTMAALLGALPLMLAGGAGAELRQPLGITMVGGLLLSQVLTLFTTPVIYLYFDRLARRW 1020 Query: 1354 AGQR 1357 A R Sbjct: 1021 AAWR 1024 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1015 bits (2625), Expect = 0.0, Method: Compositional matrix adjust. Identities = 527/1013 (52%), Positives = 702/1013 (69%), Gaps = 5/1013 (0%) Query: 335 MSISQGFIRKPVATAFLAIGITLIGLVAFVRLPVSALPSVDTPTIQVTAQLPGADPQTMG 394 M++S FI +PVATA L IG+ L G+ AF LPVS LP VD PTI V A LPGA P+TM Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 395 SSVATPLERQFGQIAGLTAMTSSSGFGNTAITLQFALNRTTDAAAQDVQAAINAAAGQLP 454 ++VATPLER G+IAG+T MTS S G+T +TLQF L+R D AA+DVQAAINA+ LP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 455 KTMPSPPIFRKVNPADVPVLLIALTSDTEPLTKVDDYADSILAQKLSQVPGVSLVTIGGM 514 +PS P +RKVNPAD P++++ LTSDT+ ++ D A +ILAQKLSQ+ GV V IGG Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 515 QKPSIRVQVNPAKLAAAGIDLEQLRSTLGNITVNQPKGVLYGNEQAYTLATNDQVLSAKG 574 P++RV++NP L GI E +R+ + N+PKG+L + +TL NDQ A+ Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 575 YEDLIIAYRNGAPVRLRDIGHAEVAAEDVTLHGWYNDKPSVILAIQRQPGANVISTVDGI 634 Y+ LIIAYRNGAPVRL D+ + +D+ +G N KPSV+L I RQPGAN+I TVD I Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 635 KKLLPQLVAGLPSDVKVTIASDRTQTIRASVDDVQFTLLLTIALVVGVIFLFLRNFWATM 694 +LP L +P+ + + + DRT TIRAS+ DV+ TL+L+I LV+ V++LFLRN AT+ Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 695 IPAISVPISLIGTFGVMYLLNYSLDNLSLMGLSIAVGFVVDDAIVMIENISRHIEEGLSP 754 IP+++VP+SLIGTFGVMYL YSLDNLSLM L++A GFVVDDAIV++EN+SRHIE G+ P Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVLENVSRHIENGMRP 420 Query: 755 LEAALKGAGEIGFTIISISVSLVAVFIPLLLMGGVIGRMFQEFAVTVCVAIAVSVIVSVT 814 ++AALKGA E+GFT++S+S SL+AVFIPLL+MGG++GR+F+EFAVT+ VAI VS+ +S+T Sbjct: 421 MQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTLSVAILVSLAISLT 480 Query: 815 LTPMMCAYLLSDHGAGT-GVVSRTLERGFVAIQRGYEAVLSVALRFKLATLTVMLASIVA 873 TPMMCA LL G R E F + GY L+ ALR TL ++LA++ Sbjct: 481 TTPMMCARLLKPASEEEPGWFHRKTEGFFNLLLDGYRHSLAWALRHSWLTLLILLATVCL 540 Query: 874 TGALFAGIPKGFFPQQDTGMITGITEASADVSPTEMAELQRSAIDVIAKDPSVANATGYI 933 G L+ +PKGFFPQQD G + G +A +S M I ++ +DP+V N G+ Sbjct: 541 NGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIVQQDPAVENVVGFT 600 Query: 934 GPGGPTVTENNGRLFVLLKPRNERQFSADEVIRQLDAKLAKLQGIAVFMQATQDINLASR 993 GG + N+G++F+ LKP ER+ SAD+VI +L KLA+ G +F+QA QDI + R Sbjct: 601 --GGSQI--NSGQMFIQLKPLAERKLSADQVINRLRGKLAREPGANLFLQAVQDIRIGGR 656 Query: 994 LSKTQYQFTLTDVNQDELNSWAGKLFEALKKRPELADVASDQANAARQLKLKIDRDAASR 1053 S QYQ+TL N +EL +W K+ +AL + L DV +D + +Q L DRD A Sbjct: 657 PSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTALVFDRDKAMA 716 Query: 1054 LGIDPAAVDNTLYDAFGQRHVAQLFTTLNTYYVILEVDPSFQSGPYALNRIYVRSSNGSM 1113 LGI P +DN L +AFGQR V+ ++ LN Y V++E P + P L IY+ +++G+ Sbjct: 717 LGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRDIYLITASGAQ 776 Query: 1114 VPLSQFTTIEYGSAALAGNHQNQFPSVTLSFNLAPGTAVGTAVAAVQQETAALHMPSTIA 1173 VPLS F+ + LA NHQ QF + TLSFNLAPG ++ A +Q + +P+T+ Sbjct: 777 VPLSTFSHYGPTNTPLAVNHQGQFAASTLSFNLAPGASLSAATQQIQDAMNRIGVPTTVH 836 Query: 1174 TSFQGNAQAFQSALASTPVLILAAIVAVYLILGMLYESTIHPITILSTLPSAGLGALMAL 1233 SFQG A+AFQ +L+S PVLIL A++ +Y++LG+LYES +HPITILSTLPSAG+GAL+AL Sbjct: 837 GSFQGTARAFQDSLSSQPVLILFALITIYIVLGVLYESYVHPITILSTLPSAGVGALLAL 896 Query: 1234 WTFGFGLDVIGLIGIILLIGLVQKNGIMLIDFALEAERHRGLSAEQSALEACKVRFRPIL 1293 VI LIG+ILLIG+V+KN IM+IDFALEAER +G+S + AC +RFRPIL Sbjct: 897 IVTDTDFSVIALIGVILLIGIVKKNAIMMIDFALEAERSQGMSPADAIFHACVLRFRPIL 956 Query: 1294 MTTMCAMLGGVPLIIGTGTGSELRQPLGFAIVGGLIVSQLLTLFTTPVVYIYL 1346 MTTM A+LG +PL +G G G+ELRQPLG +IVGGL+VSQ+LTL+TTPVVY+ L Sbjct: 957 MTTMAALLGALPLALGHGDGAELRQPLGISIVGGLLVSQILTLYTTPVVYLAL 1009 >YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1052 Score = 1003 bits (2593), Expect = 0.0, Method: Compositional matrix adjust. Identities = 530/1014 (52%), Positives = 707/1014 (69%), Gaps = 1/1014 (0%) Query: 338 SQGFIRKPVATAFLAIGITLIGLVAFVRLPVSALPSVDTPTIQVTAQLPGADPQTMGSSV 397 S+ FI +PVAT I I L G++ + LPVSALP VD PTIQV PGA P + SS+ Sbjct: 13 SRLFILRPVATTLFMIAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVVTSSI 72 Query: 398 ATPLERQFGQIAGLTAMTSSSGFGNTAITLQFALNRTTDAAAQDVQAAINAAAGQLPKTM 457 PLERQFGQ++GL M S S G + ITLQF L D A Q+VQAAINAA LP + Sbjct: 73 TAPLERQFGQMSGLKQMASQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDL 132 Query: 458 PSPPIFRKVNPADVPVLLIALTSDTEPLTKVDDYADSILAQKLSQVPGVSLVTIGGMQKP 517 P PPI+ KVNPAD P+L +A+T+ P+T+V+D ++ +AQK+SQV GV LVT+ G Q+P Sbjct: 133 PYPPIYNKVNPADPPILTLAVTATAIPMTQVEDMVETRIAQKISQVTGVGLVTLSGGQRP 192 Query: 518 SIRVQVNPAKLAAAGIDLEQLRSTLGNITVNQPKGVLYGNEQAYTLATNDQVLSAKGYED 577 ++RV++N +AA G+D E +R+ + N VN KG L G ++ TL+ NDQ+ SA+ Y D Sbjct: 193 AVRVKLNAPAVAALGLDSETIRTAISNANVNSAKGSLDGPTRSVTLSANDQMKSAEEYRD 252 Query: 578 LIIAYRNGAPVRLRDIGHAEVAAEDVTLHGWYNDKPSVILAIQRQPGANVISTVDGIKKL 637 LIIAY+NGAP+RL+D+ E AE+ L W N + +++L IQRQPG NVI+T D I+++ Sbjct: 253 LIIAYQNGAPIRLQDVATIEQGAENNKLAAWANTQSAIVLNIQRQPGVNVIATADSIREM 312 Query: 638 LPQLVAGLPSDVKVTIASDRTQTIRASVDDVQFTLLLTIALVVGVIFLFLRNFWATMIPA 697 LP+L+ LP V V + +DRT TIRASV+DVQF LLL IALVV VI+LFLRN AT+IP+ Sbjct: 313 LPELIKSLPKSVDVKVLTDRTSTIRASVNDVQFELLLAIALVVMVIYLFLRNAAATIIPS 372 Query: 698 ISVPISLIGTFGVMYLLNYSLDNLSLMGLSIAVGFVVDDAIVMIENISRHIEEGLSPLEA 757 I+VP+SL+GTF MY L +S++NL+LM L+IA GFVVDDAIV+IENISR+IE+G PL+A Sbjct: 373 IAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLDA 432 Query: 758 ALKGAGEIGFTIISISVSLVAVFIPLLLMGGVIGRMFQEFAVTVCVAIAVSVIVSVTLTP 817 ALKGAGEIGFTIIS++ SL+AV IPLL M ++GR+F+EFAVT+ VAI +S +VS+TLTP Sbjct: 433 ALKGAGEIGFTIISLTFSLIAVLIPLLFMEDIVGRLFREFAVTLAVAILISAVVSLTLTP 492 Query: 818 MMCAYLLS-DHGAGTGVVSRTLERGFVAIQRGYEAVLSVALRFKLATLTVMLASIVATGA 876 MMCA +LS + +SR E+ F + Y L L TL+V +++V T Sbjct: 493 MMCARMLSYESLRKQNRLSRASEKFFDWVIAHYAVALKKVLNHPWLTLSVAFSTLVLTVI 552 Query: 877 LFAGIPKGFFPQQDTGMITGITEASADVSPTEMAELQRSAIDVIAKDPSVANATGYIGPG 936 L+ IPKGFFP QD G+I G EA VS + MAE Q+ +I KDP+V + T ++G Sbjct: 553 LYLLIPKGFFPLQDNGLIQGTLEAPQSVSFSNMAERQQQVAAIILKDPAVESLTSFVGVD 612 Query: 937 GPTVTENNGRLFVLLKPRNERQFSADEVIRQLDAKLAKLQGIAVFMQATQDINLASRLSK 996 G T NNGRL + LKP +ER ++I +L ++ + GI +++Q QD+ + ++LS+ Sbjct: 613 GTNATLNNGRLQINLKPLSERDDRIPQIITRLQESVSGVPGIKLYLQPVQDLTIDTQLSR 672 Query: 997 TQYQFTLTDVNQDELNSWAGKLFEALKKRPELADVASDQANAARQLKLKIDRDAASRLGI 1056 TQYQFTL + +EL++W KL L+++ DV SD + + +DRD+ASRLGI Sbjct: 673 TQYQFTLQATSLEELSTWVPKLVNELQQKAPFQDVTSDWQDQGLVAFVNVDRDSASRLGI 732 Query: 1057 DPAAVDNTLYDAFGQRHVAQLFTTLNTYYVILEVDPSFQSGPYALNRIYVRSSNGSMVPL 1116 AA+DN LY+AFGQR ++ ++T N Y V+LE D G A N I + +G VPL Sbjct: 733 TMAAIDNALYNAFGQRLISTIYTQSNQYRVVLEHDVQATPGLAAFNDIRLTGIDGKGVPL 792 Query: 1117 SQFTTIEYGSAALAGNHQNQFPSVTLSFNLAPGTAVGTAVAAVQQETAALHMPSTIATSF 1176 S TIE L+ NH NQFPS T+SFNLA G ++G AVAAV + +P+ I T F Sbjct: 793 SSIATIEERFGPLSINHLNQFPSATVSFNLAQGYSLGEAVAAVTLAEKEIQLPADITTRF 852 Query: 1177 QGNAQAFQSALASTPVLILAAIVAVYLILGMLYESTIHPITILSTLPSAGLGALMALWTF 1236 QG+ AFQ+AL ST LI+AAIVA+Y++LG+LYES IHPITILSTLP+AG+GAL+AL Sbjct: 853 QGSTLAFQAALGSTLWLIIAAIVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMLT 912 Query: 1237 GFGLDVIGLIGIILLIGLVQKNGIMLIDFALEAERHRGLSAEQSALEACKVRFRPILMTT 1296 G LDVI +IGIILLIG+V+KN IM+IDFAL AER +G++ + +AC +RFRPILMTT Sbjct: 913 GNELDVIAIIGIILLIGIVKKNAIMMIDFALAAERDQGMTPYDAIYQACLLRFRPILMTT 972 Query: 1297 MCAMLGGVPLIIGTGTGSELRQPLGFAIVGGLIVSQLLTLFTTPVVYIYLQNVS 1350 + A+ G +PL++ TG G+ELRQPLG +VGGLIVSQ+LTLFTTPV+Y+ ++ Sbjct: 973 LAALFGALPLMLSTGVGAELRQPLGVCMVGGLIVSQVLTLFTTPVIYLLFDKLA 1026