BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0230.0004.p (242 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr3252 [IQR] COG1028 Dehydrogenases with different specificitie... 152 6e-37 BH0410 [IQR] COG1028 Dehydrogenases with different specificities... 127 2e-29 mll3372 [IQR] COG1028 Dehydrogenases with different specificitie... 116 4e-26 SMc00268 [IQR] COG1028 Dehydrogenases with different specificiti... 73 5e-13 lin1796 [IQR] COG1028 Dehydrogenases with different specificitie... 73 7e-13 >alr3252 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Nos Nostoc sp. PCC 7120 Length = 339 Score = 152 bits (384), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 87/220 (39%), Positives = 134/220 (60%), Gaps = 10/220 (4%) Query: 14 AGSRGIGLLCDHSDDDSVQEVFDLIRRD-HGRLDVLVNNVFAAPNVMP--VNVPFWQVPA 70 AG I + DHS+D+ V+ +F+ I+ + +G+LD+LVNN +A + PFW+ Sbjct: 76 AGGICIPVQVDHSNDEQVRLLFERIQNEQNGQLDLLVNNAYAGVQALTNAQGKPFWENEP 135 Query: 71 SLWDTMHRVGLRSHFVASQLAVPLMLPQKRGLIVNTSSGGGIRYTFNVPFGVQKSGVDRM 130 SLWD + VGLRSH++AS A +M +++GLI SS GG+ Y F +G K+G DR+ Sbjct: 136 SLWDACNNVGLRSHYIASVYAAQMMSKRQQGLICTISSWGGMAYLFGAAYGAGKAGCDRL 195 Query: 131 ARDMAHELQPFGIAAVSIWPGYIKSE---KLA--VQPERVPLALAKLIAER--GETPVFA 183 A DMA ELQP+ +A++SIWPG + +E +LA + IAER ETP+ Sbjct: 196 AADMAVELQPYNVASLSIWPGIVGTELFSRLASEMSDNHTDNGKNSAIAERYNWETPLLT 255 Query: 184 GRAVASLAGDPDVMAKSGQILLASELAAEYGFTDIDGKVP 223 GR +A LA + +V+ ++G++ + +ELA +Y D +G +P Sbjct: 256 GRVIAKLAAETNVINRTGRVQVVAELAKQYSLVDQEGNLP 295 >BH0410 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bha Bacillus halodurans Length = 302 Score = 127 bits (320), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 79/219 (36%), Positives = 116/219 (52%), Gaps = 10/219 (4%) Query: 14 AGSRGIGLLCDHSDDDSVQEVFDLIRRDHGRLDVLVNNVFAAPNVMPVNVPFWQVPASLW 73 AG GI + DH D V+ + I R+ G+LDVLVN+++ + N P WQ Sbjct: 63 AGGTGIAVPVDHLDPQKVEALVSQIEREQGKLDVLVNDIWGGELLTEWNAPVWQHSLDDG 122 Query: 74 DTMHRVGLRSHFVASQLAVPLMLPQKRGLIVNTSSGGG--IRYTFNVP--FGVQKSGVDR 129 M R+ + +H + S A+PL+L + RGL+V + G R + P + + K+ V R Sbjct: 123 LRMLRLAIDTHLITSHFALPLLL-KSRGLVVEMTDGTAEYNREHYRQPLYYDLAKTSVLR 181 Query: 130 MARDMAHELQPFGIAAVSIWPGYIKSEKLAVQPERVPLALAKLIAER-----GETPVFAG 184 MA +A ELQP AV++ PG+++SE + E + E+P F G Sbjct: 182 MAWGLAQELQPHECTAVALTPGWMRSEIMLDHFEVTERNWRDATIKEPHFVISESPRFVG 241 Query: 185 RAVASLAGDPDVMAKSGQILLASELAAEYGFTDIDGKVP 223 RAVA+LA DP+V +GQ L + +LA YGFTD+DG P Sbjct: 242 RAVAALASDPNVSRWNGQSLSSGQLAQAYGFTDLDGSKP 280 >mll3372 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 302 Score = 116 bits (291), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 76/221 (34%), Positives = 116/221 (52%), Gaps = 15/221 (6%) Query: 15 GSRGIGLLCDHSDDDSVQEVFDLIRRDHGRLDVLVNNVFAAPNVMPVNVPFWQVPASLWD 74 G GI + DH D V+ + + IR++ GRLD+LVN+++ + + P W+ Sbjct: 63 GGSGIAVQADHLVADDVRGLIERIRKEQGRLDILVNDIWGGEKLFEWDKPVWEHNLDNGL 122 Query: 75 TMHRVGLRSHFVASQLAVPLMLPQKRGLIVNTSSG----GGIRYTFNVPFGVQKSGVDRM 130 M R+ + +H + + A+PLM+ Q GL+V + G Y + + + K V+RM Sbjct: 123 RMLRLAIDTHLITAHHALPLMIEQPGGLLVEVTDGTAEYNAEHYRLSPFYDLAKVAVNRM 182 Query: 131 ARDMAHELQPFGIAAVSIWPGYIKSEKL----AVQPERVPLALAK----LIAERGETPVF 182 A A +L G +VS+ PG+++SE + V+ A AK +I+E TP F Sbjct: 183 AWAHAKDLAKHGATSVSLTPGWLRSEMMLEAFGVREVNWRDATAKVPHFIISE---TPRF 239 Query: 183 AGRAVASLAGDPDVMAKSGQILLASELAAEYGFTDIDGKVP 223 GRAVA+LA D D +GQ L + LA YGFTD+DG P Sbjct: 240 IGRAVAALAADTDRSRWNGQSLSSGGLAQVYGFTDLDGSRP 280 >SMc00268 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 252 Score = 73.2 bits (178), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 53/159 (33%), Positives = 82/159 (51%), Gaps = 16/159 (10%) Query: 15 GSRGIGLLCDHSDDDSVQEVFDLIRRDHGRLDVLVNNVFAAPNVMPVNVPFWQVPASLWD 74 G R +G+ C+ +D SV+ V D + GR+D+LVNN A P+ + ++ +D Sbjct: 55 GPRHVGMACNVTDLASVRTVMDALVSQWGRIDILVNN---AGITQPLKI--MEIAPENYD 109 Query: 75 TMHRVGLRSHFVASQLAVPLMLPQKRGLIVNTSS-----GGGIRYTFNVP-FGVQKSGVD 128 + V LR SQ +P M +K+G IVN SS GGGI F P + K+GV Sbjct: 110 AVLDVNLRGTLYCSQAVIPHMRSRKQGKIVNLSSVSAQRGGGI---FGGPHYSAAKAGVL 166 Query: 129 RMARDMAHELQPFGIAAVSIWPGYIKSEKLA--VQPERV 165 + + MA EL P + +I PG+I ++ + PE++ Sbjct: 167 GLTKAMARELAPDNVRVNAICPGFIATDITGGLLTPEKL 205 >lin1796 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Lin Listeria innocua Length = 248 Score = 72.8 bits (177), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 9/183 (4%) Query: 27 DDDSVQEVFDLIRRDHGRLDVLVNNVFAAPNVMPVNVPFWQVPASLWDTMHRVGLRSHFV 86 D + V+ +F + + GRLDV +NN AA V+ P ++ S WD + ++ Sbjct: 63 DVEKVRALFKAVDEEFGRLDVFINN--AASGVLR---PIMELEESHWDWTMNINAKALLF 117 Query: 87 ASQLAVPLMLPQKRGLIVNTSSGGGIRYTFN-VPFGVQKSGVDRMARDMAHELQPFGIAA 145 A Q A LM QK G I++ SS G IRY N GV K+ V+ + R +A EL PFGIA Sbjct: 118 AGQEAAKLMQRQKSGKIISLSSIGSIRYLENYTTVGVSKAAVESLTRYLAVELAPFGIAV 177 Query: 146 VSIWPGYIKSEKLAVQPERVPL---ALAKLIAERGETPVFAGRAVASLAGDPDVMAKSGQ 202 ++ G I++E L P R L A++K A R P AV LA + M + Sbjct: 178 NAVSGGLIETEALNHFPNREELLKDAVSKTPAGRMIEPNDLVNAVLFLASEKADMIRGQT 237 Query: 203 ILL 205 IL+ Sbjct: 238 ILV 240