BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0228.0010.p (290 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DRA0184 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Dra... 202 6e-52 PM0290 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Pmu ... 164 3e-40 pdxK [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Eco Es... 162 7e-40 ZpdxK [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase EcZ E... 161 1e-39 ECs3290 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Ecs... 161 2e-39 >DRA0184 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Dra Deinococcus radiodurans Length = 329 Score = 202 bits (515), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 122/289 (42%), Positives = 168/289 (58%), Gaps = 11/289 (3%) Query: 2 TVISIQSQVAWGHVGNSAASFPIQLHGIDVVAVPTTLLSNRPGYPTIRGRVLDVQLVADL 61 ++SIQS V++GHVGN+AA FP+Q G +V V T SN GY G V + ++A+L Sbjct: 42 NILSIQSWVSYGHVGNAAAIFPLQRLGFEVWGVHTVQFSNHTGYGAWTGPVFEPGVIAEL 101 Query: 62 LRGIEERGAVEAARLILSGYLGSADIAMDVADFVARAKAANPALLYCCDPVLGDRDRGMF 121 L GIE RG + +LSGY+GS V V R + A+P LYCCDPV+GD RG+F Sbjct: 102 LDGIEARGVLPQCDGVLSGYVGSGGTVAAVVGAVGRVRQAHPQALYCCDPVMGDVGRGVF 161 Query: 122 VRSDIPPLVRDELCPLADIITPNHFEFEFLCGARVTTIDDVVAQASALMAR----GPQTI 177 V D+P L+ + P ADI+TPN FE E L G +V T+ D +A A AL R GP+ + Sbjct: 162 VHPDLPALIAAQAIPAADIVTPNQFELELLTGQKVETLADALAAAHALRERLNPAGPRIV 221 Query: 178 VITSAELAGTPQSEIETLAIERTQSDKICAWRVRTPRIPISP--SGTGDLFAALFVAARA 235 ++TS A P S IETLA+ S W RTP +P+ P +GTGD AALF Sbjct: 222 LLTSLVRADAPASSIETLAVTGEGS-----WLCRTPLLPLDPPRNGTGDAIAALFYGQFL 276 Query: 236 RGLATPDALSHAASGIYGVLERTAQRGTEEMRIIESAGVMLDPKPRFAA 284 R + AL+ + S +Y +L+ T + GT E++++ + G P+ FAA Sbjct: 277 RTGSAEQALTLSMSALYALLDLTHRLGTREIQLVAAQGEFERPRHLFAA 325 >PM0290 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Pmu Pasteurella multocida Length = 286 Score = 164 bits (414), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 94/288 (32%), Positives = 148/288 (51%), Gaps = 7/288 (2%) Query: 3 VISIQSQVAWGHVGNSAASFPIQLHGIDVVAVPTTLLSNRPGYPTIRGRVLDVQLVADLL 62 V+SIQS V +G+ GN +A+FP+QL G+DV A+ T SN Y G V+ + + +++ Sbjct: 4 VLSIQSHVVYGYAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPKEQIGEIV 63 Query: 63 RGIEERGAVEAARLILSGYLGSADIAMDVADFVARAKAANPALLYCCDPVLGDRDRGMFV 122 RGI+ A+ I+SGY+GSA+ ++ + V K+ NP LY CDPV+G D+G V Sbjct: 64 RGIDAIEALHLCDAIVSGYIGSAEQVEEIVNAVRFIKSKNPNALYLCDPVMGHPDKGCIV 123 Query: 123 RSDIPPLVRDELCPLADIITPNHFEFEFLCGARVTTIDDVVAQASALMARGPQTIVITSA 182 + + + AD+ITPN E L G V A++A+GP+ +++ Sbjct: 124 AEGVKEGLINLAMAEADLITPNLVELRELSGLPVENFAQAQDAVRAILAKGPKKVLVKHL 183 Query: 183 ELAGTPQSEIETLAIERTQSDKICAWRVRTP--RIPISPSGTGDLFAALFVAARARGLAT 240 G S+ E L + K W + P + P G GDL A LF+A G + Sbjct: 184 SKVGKDSSQFEMLL-----ATKDGMWHISRPLHQFRKEPVGVGDLTAGLFIANLLNGKSD 238 Query: 241 PDALSHAASGIYGVLERTAQRGTEEMRIIESAGVMLDPKPRFAAVAIA 288 +A H A+ + V+ T Q+ E++II + ++ P ++ AV IA Sbjct: 239 IEAFEHTANAVNDVMTVTQQKDNYELQIIAAREYIMQPSSQYKAVKIA 286 >pdxK [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Eco Escherichia coli K12 Length = 283 Score = 162 bits (411), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 92/264 (34%), Positives = 145/264 (54%), Gaps = 6/264 (2%) Query: 3 VISIQSQVAWGHVGNSAASFPIQLHGIDVVAVPTTLLSNRPGYPTIRGRVLDVQLVADLL 62 ++++QSQV +G VGNS A I+ +G++V AVPT LLSN P Y T G + + + L Sbjct: 18 IVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYL 77 Query: 63 RGIEERGAVEAARLILSGYLGSADIAMDVADFVARAKAANPALLYCCDPVLGDRDRGMFV 122 R ++ER A+ R + +GY+G+A +A+++ + +P LL DPV+GD D G++V Sbjct: 78 RALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYV 137 Query: 123 RSDIPPLVRDELCPLADIITPNHFEFEFLCGARVTTIDDVVAQASALMARGPQTIVITSA 182 + D+P R L PLA ITPN FE E L G +D +A A +L++ + +V+TSA Sbjct: 138 KPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVTSA 197 Query: 183 ELAGTPQSEIETLAIERTQSDKICAWRVRTPRIPISPSGTGDLFAALFVAARARGLATPD 242 E++ + + + I RV+T GTGDLF A ++ +G A D Sbjct: 198 S-GNEENQEMQVVVVTADSVNVISHSRVKT-----DLKGTGDLFCAQLISGLLKGKALTD 251 Query: 243 ALSHAASGIYGVLERTAQRGTEEM 266 A+ A + V+ T Q ++E+ Sbjct: 252 AVHRAGLRVLEVMRYTQQHESDEL 275 >ZpdxK [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase EcZ Escherichia coli O157:H7 EDL933 Length = 283 Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 94/264 (35%), Positives = 149/264 (56%), Gaps = 6/264 (2%) Query: 3 VISIQSQVAWGHVGNSAASFPIQLHGIDVVAVPTTLLSNRPGYPTIRGRVLDVQLVADLL 62 ++++QSQV +G VGNS A I+ +G++V AVPT LLSN P Y T G + + + L Sbjct: 18 IVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYL 77 Query: 63 RGIEERGAVEAARLILSGYLGSADIAMDVADFVARAKAANPALLYCCDPVLGDRDRGMFV 122 R ++ER A+ R + +GY+G+A +A+++ + +P LL DPV+GD D G++V Sbjct: 78 RALQERDALRQLRAVTTGYMGTASQIKILAEWLTAXRKDHPDLLIMVDPVIGDIDSGIYV 137 Query: 123 RSDIPPLVRDELCPLADIITPNHFEFEFLCGARVTTIDDVVAQASALMARGPQTIVITSA 182 + D+P R L PLA ITPN FE E L G +D +A A +L++ + +VITSA Sbjct: 138 KPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSA 197 Query: 183 ELAGTPQSEIETLAIERTQSDKICAWRVRTPRIPISPSGTGDLFAALFVAARARGLATPD 242 +G +++ E L + T +D + + R+ GTGDLF A ++ +G A D Sbjct: 198 --SGNEENQ-EMLVVVVT-ADSVNV--ISHSRVKTDLKGTGDLFCAQLISGLLKGKALND 251 Query: 243 ALSHAASGIYGVLERTAQRGTEEM 266 A+ A + V+ T Q ++E+ Sbjct: 252 AVHRAGLRVLEVMRYTQQHESDEL 275 >ECs3290 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase Ecs Escherichia coli O157:H7 Length = 283 Score = 161 bits (407), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 94/264 (35%), Positives = 149/264 (56%), Gaps = 6/264 (2%) Query: 3 VISIQSQVAWGHVGNSAASFPIQLHGIDVVAVPTTLLSNRPGYPTIRGRVLDVQLVADLL 62 ++++QSQV +G VGNS A I+ +G++V AVPT LLSN P Y T G + + + L Sbjct: 18 IVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYL 77 Query: 63 RGIEERGAVEAARLILSGYLGSADIAMDVADFVARAKAANPALLYCCDPVLGDRDRGMFV 122 R ++ER A+ R + +GY+G+A +A+++ + +P LL DPV+GD D G++V Sbjct: 78 RALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYV 137 Query: 123 RSDIPPLVRDELCPLADIITPNHFEFEFLCGARVTTIDDVVAQASALMARGPQTIVITSA 182 + D+P R L PLA ITPN FE E L G +D +A A +L++ + +VITSA Sbjct: 138 KPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSA 197 Query: 183 ELAGTPQSEIETLAIERTQSDKICAWRVRTPRIPISPSGTGDLFAALFVAARARGLATPD 242 +G +++ E L + T +D + + R+ GTGDLF A ++ +G A D Sbjct: 198 --SGNEENQ-EMLVVVVT-ADSVNV--ISHSRVKTDLKGTGDLFCAQLISGLLKGKALND 251 Query: 243 ALSHAASGIYGVLERTAQRGTEEM 266 A+ A + V+ T Q ++E+ Sbjct: 252 AVHRAGLRVLEVMRYTQQHESDEL 275