BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0227.0029.p (89 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR0467_2 [ER] COG1387 Histidinol phosphatase and related hydrola... 87 6e-18 Rv3856c [ER] COG1387 Histidinol phosphatase and related hydrolas... 68 5e-12 MT3971 [ER] COG1387 Histidinol phosphatase and related hydrolase... 68 5e-12 BS_yshC_2 [ER] COG1387 Histidinol phosphatase and related hydrol... 67 7e-12 aq_1422_2 [ER] COG1387 Histidinol phosphatase and related hydrol... 64 8e-11 >DR0467_2 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family Dra Deinococcus radiodurans Length = 246 Score = 87.4 bits (215), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 42/75 (56%), Positives = 53/75 (70%) Query: 1 VVASIHGRFKLDRKAQTQRLLRAISDPHTTIIGHMTGRQLQRRPGYEIDVEKVLRACAKH 60 VV S+H F LD QT+RL+RA+S P T++GH TGR L RRPGY +D++ VL AC + Sbjct: 97 VVVSVHSNFTLDAARQTERLIRAVSHPLVTVLGHATGRLLLRRPGYALDLDAVLGACEAN 156 Query: 61 DVVVEINAHPWRLDL 75 VVEINA+ RLDL Sbjct: 157 GTVVEINANAARLDL 171 >Rv3856c [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family Mtu Mycobacterium tuberculosis H37Rv Length = 335 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 33/78 (42%), Positives = 48/78 (61%), Gaps = 4/78 (5%) Query: 1 VVASIHGRFKLDRKAQTQRLLRAISDPHTTIIGHMTGRQLQR----RPGYEIDVEKVLRA 56 VVAS+H + +D A T+R++RA+++ HT ++GH TGR + RP + D E V A Sbjct: 194 VVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIRPESKFDAEAVFTA 253 Query: 57 CAKHDVVVEINAHPWRLD 74 C +H VEIN+ P R D Sbjct: 254 CREHGTAVEINSRPERRD 271 >MT3971 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family MtC Mycobacterium tuberculosis CDC1551 Length = 335 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 33/78 (42%), Positives = 48/78 (61%), Gaps = 4/78 (5%) Query: 1 VVASIHGRFKLDRKAQTQRLLRAISDPHTTIIGHMTGRQLQR----RPGYEIDVEKVLRA 56 VVAS+H + +D A T+R++RA+++ HT ++GH TGR + RP + D E V A Sbjct: 194 VVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIRPESKFDAEAVFTA 253 Query: 57 CAKHDVVVEINAHPWRLD 74 C +H VEIN+ P R D Sbjct: 254 CREHGTAVEINSRPERRD 271 >BS_yshC_2 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family Bsu Bacillus subtilis Length = 236 Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 32/75 (42%), Positives = 47/75 (62%) Query: 1 VVASIHGRFKLDRKAQTQRLLRAISDPHTTIIGHMTGRQLQRRPGYEIDVEKVLRACAKH 60 V+ASIH F +RL A+++ H II H TGR + RR GYEID+++++ K Sbjct: 98 VIASIHSSFNQPEHVIMKRLETALTNKHVDIIAHPTGRLIGRRAGYEIDIDQLIELARKT 157 Query: 61 DVVVEINAHPWRLDL 75 + +E+NA+P RLDL Sbjct: 158 NTALELNANPARLDL 172 >aq_1422_2 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family Aae Aquifex aeolicus Length = 239 Score = 63.9 bits (154), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 11/89 (12%) Query: 1 VVASIHGRFKLDRKAQTQRLLRAISDPHTTIIGHMTGRQLQRRPGYEIDVEKVLRACAKH 60 VVAS+H RF+ D T+R+++A+ +P+ +IGH TG+Q R GY +++EK+++ + Sbjct: 100 VVASVHSRFEQD---NTERIIKAMENPYVNMIGHPTGKQYGYREGYPVNIEKLIQKAKET 156 Query: 61 DVVVEINAHPWRLDLVGAGTGQPSNLAAC 89 +E+N R+DL P N+ C Sbjct: 157 GTALELNTQ--RMDL------SPENVRKC 177