BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0226.0019.p (601 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 114 5e-25 SMa0579 [T] COG2114 Adenylate cyclase, family 3 (some proteins c... 113 2e-24 PA3217 [T] COG2114 Adenylate cyclase, family 3 (some proteins co... 110 7e-24 TP0485 Non COG 110 1e-23 all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 108 3e-23 >alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 114 bits (286), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 69/217 (31%), Positives = 119/217 (54%), Gaps = 6/217 (2%) Query: 389 QERIAK--LKRFLAPQVADLVDRAGDDSVLDGRRTDVVVVFCDLRGFTAFSAGVTPEEVM 446 QE+ K + R+L P VA+ V G+D+++ G R +V V+F D+RG+T + + EV+ Sbjct: 1 QEKRLKTTMYRYLTPHVAEQVMALGEDALMVGERKEVTVLFSDIRGYTTLTENLGAAEVV 60 Query: 447 SVLSEYYEVLGRVIARFEATLISFSGDGLMVLVNAPVPV-EEPALRAVDLATEMQKHVQG 505 S+L++Y+E + + +E TL F GD LM + AP+P+ E A +AV A +M++ ++ Sbjct: 61 SLLNQYFETMVEAVFNYEGTLDKFIGDALMAVFGAPLPLTENHAWQAVQSALDMRQRLKE 120 Query: 506 LIGGWRSRGY-QVGFGIGLASGSATVGRIGYDDRLDYTAIGSVVNLAARLCASAADR--E 562 + Q+ GIG++SG G IG R+DYT IG VNL++RL + + Sbjct: 121 FNQRRIIQAQPQIKIGIGISSGEVVSGNIGSHKRMDYTVIGDGVNLSSRLETVTKEYGCD 180 Query: 563 ILMDAGTAASVRGKRAVEDIGSRQIKGFDDAIPVFGI 599 I++ T + V + ++KG A+ ++ + Sbjct: 181 IILSEFTYQLCSDRIWVRQLDKIRVKGKHQAVNIYEL 217 >SMa0579 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Sme Sinorhizobium meliloti Length = 809 Score = 113 bits (282), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 70/208 (33%), Positives = 109/208 (52%), Gaps = 6/208 (2%) Query: 393 AKLKRFLAPQVADLVDRAGDDSVLDGRRTDVVVVFCDLRGFTAFSAGVTPEEVMSVLSEY 452 AKL ++LAPQV + + D ++ RR + + F D+ FT + + EE+ +L++Y Sbjct: 548 AKLAKYLAPQVYNSIFSGKQDVRIESRRKKLTICFSDIAAFTETTDKMESEELTQLLNQY 607 Query: 453 YEVLGRVIARFEATLISFSGDGLMVLVNAPVP--VEEPALRAVDLATEMQKHVQGLIGGW 510 + ++ F AT+ + GD +++ P + E A+ V +A MQ+ + L W Sbjct: 608 LTEMSKIALSFGATIDKYVGDAILMFFGDPETRGIREDAIACVSMALAMQERMGELGETW 667 Query: 511 RSRGYQVGFG--IGLASGSATVGRIGYDDRLDYTAIGSVVNLAARLCASAADREILMDAG 568 RS G ++ IG+ + TVG G +DR+DYT IG VNLAARL AA +L+ Sbjct: 668 RSVGIEMPLRCRIGIHTDYCTVGNFGSEDRMDYTIIGGAVNLAARLEEEAAPGSVLISYE 727 Query: 569 TAASVRGKRAVEDIGSRQIKGFDDAIPV 596 T A V+ E+ G QI+G A PV Sbjct: 728 TFAQVKDLIHCEETGRVQIRGI--AYPV 753 >PA3217 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Pae Pseudomonas aeruginosa Length = 463 Score = 110 bits (276), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 5/224 (2%) Query: 381 ELALAQQHQERIAK-LKRFLAPQVADLVDRAGDDSVLDGRRTDVVVVFCDLRGFTAFSAG 439 E+A Q+ R+A+ L ++L+PQV +++ L+ +R + V F D+RGFT S Sbjct: 185 EIAREQEKAARLARNLAKYLSPQVWEMIFSGKKSVRLETQRKKLTVFFSDIRGFTELSEE 244 Query: 440 VTPEEVMSVLSEYYEVLGRVIARFEATLISFSGDGLMVLVNAPVP--VEEPALRAVDLAT 497 + E + +L+ Y + ++ ++ T+ F GD +MV P ++ A+ AV + Sbjct: 245 LEAEALTDLLNNYLNEMSKIALKYGGTIDKFVGDCVMVFFGDPSTQGAKKDAVAAVSMGI 304 Query: 498 EMQKHVQGLIGGWRSRGYQVGFGI--GLASGSATVGRIGYDDRLDYTAIGSVVNLAARLC 555 M+KH++ L WR++G I G+ +G TVG G D R+DYT IG VNLA+RL Sbjct: 305 AMRKHMKVLRQQWRAQGITKPLEIRMGINTGYCTVGNFGADTRMDYTIIGREVNLASRLE 364 Query: 556 ASAADREILMDAGTAASVRGKRAVEDIGSRQIKGFDDAIPVFGI 599 +++ EIL+ T + ++ D G +KGF + ++ + Sbjct: 365 SASEAGEILISHETYSLIKDVIMCRDKGQIAVKGFSRPVQIYQV 408 >TP0485 Non COG Length = 614 Score = 110 bits (274), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 99/382 (25%), Positives = 164/382 (42%), Gaps = 16/382 (4%) Query: 224 TGFAFVLDRPGRLIAHPDISLVLRGLEETTSQPFRAIRDAIGPGASVA-TGRDGQGRRVA 282 +G + + G + HP+ SL + S R +R++ ++ G D + R Sbjct: 199 SGTMYAVTWAGNSLYHPEYSLNYSNINLQDSPVVRDLRESTQLTKQISFIGTDNK-RYFG 257 Query: 283 ASAAPVAGPDWTVVVAQPLSEAYAPIYAALRRTTVLLAGSTVFAGLLAYAFAHRMTEPIR 342 A A G + +V+ P+S Y +Y A+ +L + + LL + A +T PI Sbjct: 258 AFAKQTFG-KFAIVLETPMSVVYQAVYYAIILDGILTGMVLLASILLVWFIAQSITRPIL 316 Query: 343 LLEEGTERIGAGSFEHRIAIQTGDEFQRLANSFNRMAGELALAQQHQERIAKLKRFLAPQ 402 L T I +G F I + DE L +F M LA ++ +E K Sbjct: 317 TLVGATHAISSGQFLLDIKPSSKDEIGLLTETFVSMGRGLAERERMKEAFGKFVN----- 371 Query: 403 VADLVDRAGDDSV-LDGRRTDVVVVFCDLRGFTAFSAGVTPEEVMSVLSEYYEVLGRVIA 461 D+ ++A + L G R + F D+R FT S + PE+V+ L+EY + I Sbjct: 372 -RDIAEKAMKGELALGGERKTATIFFSDVRSFTEMSEKLPPEDVVEFLNEYMSCMVDCIE 430 Query: 462 RFEATLISFSGDGLMVLVNAPVPVEEPALRAVDLATEMQKHVQGLIGGWRSR----GYQV 517 + + F GD +M + APV + L A+ + + LI R ++ Sbjct: 431 QTGGVVDKFIGDAIMAIWGAPVSLGSARLDALQSMKAVFLMRESLIQLNEKRVACSKPRI 490 Query: 518 GFGIGLASGSATVGRIGYDDRLDYTAIGSVVNLAARLCA--SAADREILMDAGTAASVRG 575 G G G+ +GS G+IG R++YT IG VN A+R+ A + L+ T V+ Sbjct: 491 GIGCGVNTGSCVAGQIGSSKRMEYTVIGDAVNTASRIEALNKPFGTDFLISENTYELVKD 550 Query: 576 KRAVEDIGSRQIKGFDDAIPVF 597 VE + +KG + + V+ Sbjct: 551 MLIVEKMPPITVKGKREPLNVY 572 >all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 322 Score = 108 bits (270), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 69/213 (32%), Positives = 108/213 (50%), Gaps = 13/213 (6%) Query: 395 LKRFLAPQVADLVDRAGDDSVLDGRRTDVVVVFCDLRGFTAFSAGVTPEEVMSVLSEYYE 454 L R+L +V + L G R V ++F DLRGF+A S ++PE+V+ +L+ Y Sbjct: 1 LGRYLTDEVLANILETPSGLKLGGERRKVTLLFSDLRGFSAMSEQLSPEQVVQILNLYLG 60 Query: 455 VLGRVIARFEATLISFSGDGLMVLVNAPVPVEEPALRAVDLATEMQKHVQGLIGGWRSRG 514 V+ VI +++ T+ F GDG+ ++ AP+ + + RA+ A MQ+ +Q + Sbjct: 61 VMTDVINQYKGTINEFIGDGIFIMFGAPICRPDDSQRAIACAIAMQRAMQQVNAKTHQMN 120 Query: 515 Y-QVGFGIGLASGSATVGRIGYDDRLDYTAIGSVVNLAARLCASAADREILM------DA 567 Q+ GIG+ +G G IG R YT IGS VNLAAR+ +IL+ DA Sbjct: 121 LPQLEMGIGINTGEVVAGNIGSQKRAQYTVIGSHVNLAARIETYTVGGQILISENTRQDA 180 Query: 568 GTAASVRGKRAVEDIGSRQIKGFDDAIPVFGIS 600 T + G+ +E KG + I ++ IS Sbjct: 181 NTDLQIAGQMQIEP------KGIKEPITIYEIS 207