BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0225.0005.p (238 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr6764 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphoryl... 189 4e-48 DR0710 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphoryla... 171 1e-42 Cj1329_2 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphory... 145 7e-35 BH1416 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphoryla... 145 8e-35 sll1496_1 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphor... 137 2e-32 >mlr6764 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Mlo Mesorhizobium loti Length = 240 Score = 189 bits (480), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 100/218 (45%), Positives = 144/218 (66%), Gaps = 8/218 (3%) Query: 3 KALIMAGGKGTRLKPFTASFPKPLVPLGDLPVLELLLRQLKAAGVQEVVLSVNHLHHLIR 62 KA+I GG GTRL+PFT+ PKPL+P+G PVLELLL+ L+ G++EV ++ +L HLIR Sbjct: 2 KAVIQCGGMGTRLRPFTSVLPKPLMPIGARPVLELLLKWLRRNGIEEVYITTGYLGHLIR 61 Query: 63 AFCEDGSKFGLKIDYVLEDEPLGTAGSLAYALDKLSDDFIVANGDLLTNFNIAKMVQEHR 122 + C DGS++ LKI Y E EPLGT G L+ D+L++ F+V NGD+LT+ ++++ V HR Sbjct: 62 SVCGDGSQWNLKIRYTQEMEPLGTIGPLSLIRDELNETFVVLNGDVLTDLSLSRFVAAHR 121 Query: 123 TQPTAASIAVFKRSTKIEFGLV-EVDGNMRLTGYREKPTYSHLVSMGLYVLNRGSV--AP 179 +IA R K++FG++ EV+ ++L +REKPT SHLVSMG+Y +N + P Sbjct: 122 MHKDPVTIATACRLIKMDFGVIDEVNNAVQL--FREKPTLSHLVSMGIYCMNPDVLRFIP 179 Query: 180 HLVPGKYLDMPHLMQILIEAGKSVLCRSQDCLWLDIGR 217 +P + D LM +++ G +V D LWLDIGR Sbjct: 180 SGIPFGFDD---LMLQMMQGGTTVHVYKHDGLWLDIGR 214 >DR0710 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Dra Deinococcus radiodurans Length = 282 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 93/235 (39%), Positives = 140/235 (59%), Gaps = 5/235 (2%) Query: 4 ALIMAGGKGTRLKPFTASFPKPLVPLG-DLPVLELLLRQLKAAGVQEVVLSVNHLHHLIR 62 A+I+AGG+GTRL+P+T PKPLVP+G +L +LE++L QLK+ G V L+V HL HLIR Sbjct: 38 AVILAGGQGTRLRPYTTRVPKPLVPIGGELSILEIVLHQLKSFGFTRVTLAVGHLSHLIR 97 Query: 63 AFCEDGSKFGLKIDYVLEDEPLGTAGSLAYALDKLSDDFIVANGDLLTNFNIAKMVQEHR 122 AF +G ++GL IDY E+ PLGT G + L L + F++ NGD+LT+ N ++ H Sbjct: 98 AFVGNGRQYGLDIDYTEEETPLGTIGPVLNVLPWLPEHFLIMNGDVLTDLNYGAFLRGHM 157 Query: 123 TQPTAASIAVFKRSTKIEFGLVEV-DGNMRLTGYREKPTYSHLVSMGLYVLNRGSVAPHL 181 +++ + R + EFG+++V D + +REKP VSMG+Y + + ++ Sbjct: 158 ASGDPLTVSTYHREIRSEFGVLDVDDSGEHIVAFREKPAVPFQVSMGVYGMTKSTLG-RY 216 Query: 182 VPGKYLDMPHLMQILIEAGKSVLCRSQDCLWLDIGRP--XATAQQLFEEKRELFL 234 PG+ L LM L+ AG+ WLDIGRP TA + + E +++ L Sbjct: 217 QPGQVLGFDTLMLDLLAAGERPRSDLFGGYWLDIGRPEDYDTANEQWNEMQKVLL 271 >Cj1329_2 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cje Campylobacter jejuni Length = 228 Score = 145 bits (366), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 74/214 (34%), Positives = 121/214 (56%), Gaps = 3/214 (1%) Query: 5 LIMAGGKGTRLKPFTASFPKPLVPLGDLPVLELLLRQLKAAGVQEVVLSVNHLHHLIRAF 64 +IMAGG G+RLK T PKP++ +G P+LE ++++LK + + VN+ +I + Sbjct: 7 IIMAGGLGSRLKELTKDTPKPMLKVGKKPILESIIQRLKNQNFENFIFCVNYKKQIIEDY 66 Query: 65 CEDGSKFGLKIDYVLEDEPLGTAGSLAYALDKLSDDFIVANGDLLTNFNIAKMVQEHRTQ 124 + G KFG+KI Y+ E + LGTAG+L+ + + FIV N D+LT + +++ H+ Sbjct: 67 FQKGQKFGVKISYIKERKKLGTAGALSLIKQEFKESFIVMNADILTELDFNALLKAHKKS 126 Query: 125 PTAASIAVFKRSTKIEFGLVEVDGNMRLTGYREKPTYSHLVSMGLYVLNRGSVAPHLVPG 184 S+ V + +I +G++ + EKPT LVS G+YVL + + Sbjct: 127 KALMSVCVREFEQQIPYGVITQKQGF-IENIEEKPTQKFLVSAGIYVL-ENEILNLIAKN 184 Query: 185 KYLDMPHLMQILIEAGKSVLCRSQDCLWLDIGRP 218 +YLDMP L++++++ GK D W+DIGRP Sbjct: 185 EYLDMPELIKLVLQKGKVNTYIIND-YWIDIGRP 217 >BH1416 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Bha Bacillus halodurans Length = 249 Score = 145 bits (366), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 79/219 (36%), Positives = 130/219 (59%), Gaps = 6/219 (2%) Query: 3 KALIMAGGKGTRLKPFTASFPKPLVPLGDLPVLELLLRQLKAAGVQEVVLSVNHLHHLIR 62 K +I+AGG+GTRLKP T PKP++P+ +P L L L A G++++V+ V++L+H ++ Sbjct: 2 KGVILAGGRGTRLKPLTDQIPKPMLPIAGVPCLAHGLAHLAAHGIRDIVMLVHYLNHQMK 61 Query: 63 AFCEDGSKFGLKIDYVLEDEPLGTAGSLAYALDKLSDDFIVANGDLLTNFNIAKMVQEHR 122 A+ +DGSK+G++I YV ED PLGTAGSL A L + F+V +GD+LT +I + + H+ Sbjct: 62 AYFQDGSKYGMRITYVQEDAPLGTAGSLKAAERYLDEPFVVMSGDVLTTISIQEAIVFHK 121 Query: 123 TQPTAASIAVFKRSTKIEFGLVEVDGNMRLTGYREKPTYSH----LVSMGLYVLNRGSVA 178 Q + ++ + +G+V+ N R+ +REKPT LV+ GLYV++ V Sbjct: 122 RQNSLMTMLTKRVKNGQNYGVVQTGPNHRVVAFREKPTEDKTREVLVNTGLYVMDP-FVL 180 Query: 179 PHLVPGKYLDM-PHLMQILIEAGKSVLCRSQDCLWLDIG 216 ++ G +D+ ++ L++ + W DIG Sbjct: 181 SYIPKGSAVDLGKDVIPYLVDRKLDIFALEGGGYWRDIG 219 >sll1496_1 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Syn Synechocystis Length = 383 Score = 137 bits (346), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 7/231 (3%) Query: 3 KALIMAGGKGTRLKPFTASFPKPLVPLGDLPVLELLLRQLKAAGVQEVVLSVNHLHHLIR 62 +A++MAGG GTRL+P T PKP+VP+ + P+ ++ L+ + EVV ++++L +R Sbjct: 2 RAVLMAGGAGTRLRPLTCDLPKPMVPIVNQPIAAHIIHLLRRHNITEVVATLHYLPDAMR 61 Query: 63 AFCEDGSKFGLKIDYVLEDE-PLGTAGSLAYALDKLSDDFIVANGDLLTNFNIAKMVQEH 121 + DGS+FG+++ Y +EDE PLGTAG + + L D F+V +GD +T+FN+ + + H Sbjct: 62 DYFLDGSEFGVQMTYAVEDEHPLGTAGCVKNIEELLDDTFLVISGDSITDFNLTQAIAFH 121 Query: 122 RTQPTAASIAVFKRSTKIEFGLVEVDGNMRLTGYREKPT----YSHLVSMGLYVLNRGSV 177 + + A++ + K +EFG+V D N R+ + EKP+ +S V+ G Y+L V Sbjct: 122 KQKQAKATLILTKVPNPLEFGVVITDENQRVQRFLEKPSTSEVFSDTVNTGTYIL-EPEV 180 Query: 178 APHLVPGKYLDMPH-LMQILIEAGKSVLCRSQDCLWLDIGRPXATAQQLFE 227 +L P + +D L +L+E + + D W D+G A + ++ Sbjct: 181 LAYLPPKEEMDFSKDLFPLLLENDEPMYGFVADGYWCDVGNLDAYREAQYD 231