BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0224.0021.p (284 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Rv1935c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu ... 231 1e-60 MT1985 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC M... 231 1e-60 SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso ... 124 4e-28 SSO0654 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso ... 119 8e-27 PAE1383_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Py... 117 4e-26 >Rv1935c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu Mycobacterium tuberculosis H37Rv Length = 318 Score = 231 bits (590), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 128/261 (49%), Positives = 159/261 (60%), Gaps = 5/261 (1%) Query: 5 QFETIVVERPEPA-IARIVMNRPEARNAQNLQMTYDLNAAFDRAVQDDAVKVIILAGNGP 63 +FE I E + IA I ++RP+ RNAQ M +L AAF+ A DD V+V+IL GP Sbjct: 23 EFEYIRYETIDDGRIAAITLDRPKQRNAQTRGMLVELGAAFELAEADDTVRVVILRAAGP 82 Query: 64 HFSAGHDLRPG---AKNQAGVDFPPVGNWGGFAEPNAHGRFAREQEIYLQITRRWRNLAK 120 FSAGHDL + G D P G R +E Y + T+RWRNL K Sbjct: 83 AFSAGHDLGSADDIRERSPGPDQHPSYRCNGATFGGVESRNRQEWHYYFENTKRWRNLRK 142 Query: 121 PTIAEVHGKCIAGGLMLAWACDLIVASNDAEFCDPVVT-MGVCGVEWFVHPWELGARKAK 179 TIA+VHG ++ GLMLAW CDLIVAS D F D V T +G+CGVE+F HPWE G RK K Sbjct: 143 ITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFGHPWEFGPRKTK 202 Query: 180 EMLFTADVWSADEAHRLGMVNHVVPRGDLSSFTLALARRIAAKPAFALKLAKEAVNRSID 239 E+L T D ADEAH LGMV+ V P +L++ T+ ARRIA P A L KE+VN+++D Sbjct: 203 ELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPTMAALLIKESVNQTVD 262 Query: 240 IMGQPAAIDQAFALHQLCHAH 260 MG AA+D F +HQL HAH Sbjct: 263 AMGFSAALDGCFKIHQLNHAH 283 >MT1985 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC Mycobacterium tuberculosis CDC1551 Length = 318 Score = 231 bits (590), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 128/261 (49%), Positives = 159/261 (60%), Gaps = 5/261 (1%) Query: 5 QFETIVVERPEPA-IARIVMNRPEARNAQNLQMTYDLNAAFDRAVQDDAVKVIILAGNGP 63 +FE I E + IA I ++RP+ RNAQ M +L AAF+ A DD V+V+IL GP Sbjct: 23 EFEYIRYETIDDGRIAAITLDRPKQRNAQTRGMLVELGAAFELAEADDTVRVVILRAAGP 82 Query: 64 HFSAGHDLRPG---AKNQAGVDFPPVGNWGGFAEPNAHGRFAREQEIYLQITRRWRNLAK 120 FSAGHDL + G D P G R +E Y + T+RWRNL K Sbjct: 83 AFSAGHDLGSADDIRERSPGPDQHPSYRCNGATFGGVESRNRQEWHYYFENTKRWRNLRK 142 Query: 121 PTIAEVHGKCIAGGLMLAWACDLIVASNDAEFCDPVVT-MGVCGVEWFVHPWELGARKAK 179 TIA+VHG ++ GLMLAW CDLIVAS D F D V T +G+CGVE+F HPWE G RK K Sbjct: 143 ITIAQVHGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEYFGHPWEFGPRKTK 202 Query: 180 EMLFTADVWSADEAHRLGMVNHVVPRGDLSSFTLALARRIAAKPAFALKLAKEAVNRSID 239 E+L T D ADEAH LGMV+ V P +L++ T+ ARRIA P A L KE+VN+++D Sbjct: 203 ELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKVPTMAALLIKESVNQTVD 262 Query: 240 IMGQPAAIDQAFALHQLCHAH 260 MG AA+D F +HQL HAH Sbjct: 263 AMGFSAALDGCFKIHQLNHAH 283 >SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 266 Score = 124 bits (310), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 121/242 (50%), Gaps = 28/242 (11%) Query: 6 FETIVVERPEPAIARIVMNRPEARNAQNLQMTYDLNAAFDRAVQDDAVKVIILAGNGPHF 65 + TI +E + I I +NRP+ NA N QM +L ++ DD +KV+I+ GNG F Sbjct: 9 YSTIQIEVID-NIGIIKLNRPDKLNAINFQMVDELVDVLNKLDNDDKIKVVIITGNGKAF 67 Query: 66 SAGHDLRPGAKNQAGVDFPPVGNWGGFAEPNAHGRFAREQEIYLQITRRWRNLAKPTIAE 125 SAG D++ ++ P E G ++ + + R KP IA Sbjct: 68 SAGADVKEM------LETP-------LEEIMKKG--------HMPLWEKLRTFKKPVIAA 106 Query: 126 VHGKCIAGGLMLAWACDLIVASNDAEFCDPVVTMGVC----GVEWFVHPWELGARKAKEM 181 ++G GGL LA ACD+I+AS A+ P + +G+ G + LG KA E+ Sbjct: 107 LNGITAGGGLELAMACDIIIASESAKLGQPEINLGIMPGAGGTQRLTRV--LGKYKAMEL 164 Query: 182 LFTADVWSADEAHRLGMVNHVVPRGDLSSFTLALARRIAAKPAFALKLAKEAVNRSIDIM 241 + T + + EA R G+VN VVP L + LAR IA KP ++ LAKEAV R+ D + Sbjct: 165 VLTGKLIDSKEAERYGLVNKVVPDNSLIDEAIRLAREIAEKPIISIILAKEAVARAWDTL 224 Query: 242 GQ 243 Q Sbjct: 225 LQ 226 >SSO0654 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 252 Score = 119 bits (298), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 85/255 (33%), Positives = 120/255 (47%), Gaps = 31/255 (12%) Query: 6 FETIVVERPEPAIARIVMNRPEARNAQNLQMTYDLNAAFDRAVQDDAVKVIILAGNGPHF 65 ETIV + EP I IV+NRP+ N+ N M ++ + V +D +KV+I G+G F Sbjct: 1 METIVT-KEEPPIEWIVLNRPDKLNSINSIMIREIGDILRQIVDNDKIKVVIFTGSGKAF 59 Query: 66 SAGHDLRPGAKNQAGVDFPPVGNWGGFAEPNAHGRFAREQEIYLQITRRWRNLAKPTIAE 125 SAG D+ D PV W FA + + R+ KPTIA Sbjct: 60 SAGADISQFK------DLDPVKAW----------EFAIKGRELMDYIERY---PKPTIAM 100 Query: 126 VHGKCIAGGLMLAWACDLIVASNDAEFCDPVVTMGVC----GVEWFVHPWELGARKAKEM 181 ++G + GGL LA +CDL +AS AE P + +G+ G + V +G +A E+ Sbjct: 101 INGYALGGGLELALSCDLRIASQIAELGLPEINLGIYPGFGGTQRLVRL--IGKGRAMEI 158 Query: 182 LFTADVWSADEAHRLGMVNHVVPRGDLSSFTLALARRIAAKPAFALKLAKEAVNRSIDIM 241 + D+ AD A R+G+VN VV L LA ++A KP A++L K VN Sbjct: 159 IMLGDIIKADYAERIGLVNRVVEPSSLEKEVRELALKLAEKPQIAIRLIKTVVN-----Y 213 Query: 242 GQPAAIDQAFALHQL 256 G A I L L Sbjct: 214 GNDAPILSGLTLESL 228 >PAE1383_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pya Pyrobaculum aerophilum Length = 259 Score = 117 bits (292), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 84/240 (35%), Positives = 122/240 (50%), Gaps = 28/240 (11%) Query: 6 FETIVVERPEPAIARIVMNRPEARNAQNLQMTYDLNAAFDRAVQ--DDAVKVIILAGNGP 63 ET++V R EP IA I++NRPE NA N +M +L D Q D V+V+++ G+G Sbjct: 1 LETLIV-RYEPGIAWIILNRPERLNAINPKMIEELWKVLDEIEQMDYDKVRVVVITGSGR 59 Query: 64 HFSAGHDLRPGAKNQAGVDFPPVGNWGGFAEPNAHGRFAREQEIYLQITRRWRNLAKPTI 123 FSAG D+ G G A P + +R+ ++ + R L +P I Sbjct: 60 AFSAGADV--------------TGFMG--ATPVTIFKVSRKLQMLYE---RLELLDRPVI 100 Query: 124 AEVHGKCIAGGLMLAWACDLIVASNDAEFCDPVVTMGVC----GVEWFVHPWELGARKAK 179 ++G + GGL LA ACD +A+ AE P + +G G + +G KAK Sbjct: 101 CGLNGYTLGGGLELAMACDFRIAAETAELGQPEINLGFIPGAGGTQRLARL--IGRDKAK 158 Query: 180 EMLFTADVWSADEAHRLGMVNHVVPRGDLSSFTLALARRIAAKPAFALKLAKEAVNRSID 239 E++FT D A EA RLG+V+ VVP L A A ++A KP AL +AK A+N ++ Sbjct: 159 ELIFTGDRIPAREAERLGLVHKVVPPDRLEQELRAFANKLAEKPPLALAMAKYAINFGLE 218