BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0224.0011.p (888 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YKL157w [E] COG0308 Aminopeptidase N Sce Saccharomyces cerevisiae 396 e-109 YHR047c [E] COG0308 Aminopeptidase N Sce Saccharomyces cerevisiae 381 e-105 SPBC1921.05 [E] COG0308 Aminopeptidase N Spo Schizosaccharomyces... 360 7e-99 SSO2154 [E] COG0308 Aminopeptidase N Sso Sulfolobus solfataricus 319 2e-86 TVN0800 [E] COG0308 Aminopeptidase N Tvo Thermoplasma volcanium 311 5e-84 >YKL157w [E] COG0308 Aminopeptidase N Sce Saccharomyces cerevisiae Length = 935 Score = 396 bits (1017), Expect = e-109, Method: Compositional matrix adjust. Identities = 254/861 (29%), Positives = 421/861 (48%), Gaps = 23/861 (2%) Query: 25 TMAAGAQAEQTFSF-DRTPGK--LPKTVVPLHYAIELRPDITSLALPGVETVDIEVRE-A 80 T A A+ ++T ++TP + LP VVPLHY + + PD + G +++++ A Sbjct: 79 TSHACAKCQKTSQLLNKTPNREILPDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPA 138 Query: 81 TAQLTLNAVNTTFTDVTIDDSAQRAEVATDATAQTATLTFAKPLAA---GRHKLRIVFAA 137 +TLN V+T I D +E+ ++ Q T F K + G L I F Sbjct: 139 IDTVTLNTVDTDIHSAKIGD-VTSSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTG 197 Query: 138 QINKFGTGLFSVDYPTR-TG-IKRMISSKLEPADARRIFPCWDEPSFKASFALTVVIPRN 195 +N G + Y + TG K M ++++EP DARR FPC+DEP+ KASFA+T+V + Sbjct: 198 ILNDNMAGFYRAKYEDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPS 257 Query: 196 LLAVGNMPVTDEEPVAGDLKKVA-FAPTPKMSSYLFVLAVGELERVTADAGGVTVGVVTT 254 L + NM V +E D KKV F TPKMS+YL V EL+ V + + V V T Sbjct: 258 LTHLSNMDVKNE--YVKDGKKVTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYAT 315 Query: 255 EGKGGQGRFALDSAVKLLAYYNDYFGVKYPLPKLDLIAVPGGFGGAMENWGGITFFESRL 314 G G+FA D K LA++ FG++YPLPK+D +AV GAMENWG +T+ L Sbjct: 316 PGNEKHGQFAADLTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDL 375 Query: 315 LFDPAISAETARRGIFAIIAHEMAHMWFGDLVTMAWWDNLWLNEGFASWMATKASEQFYP 374 L D S + + ++ HE+AH WFG+LVTM WW+ LWLNEGFA+WM+ + +F P Sbjct: 376 LLDKDNSTLDRIQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQP 435 Query: 375 EWQGWLNGY-GAKQFAMTLDARRTSHPVQQPIADHSEAVTAFDAITYNKGQALIRMLETY 433 EW+ W Q A++LD+ R+SHP++ P+ E FDAI+Y+KG +L+RM+ + Sbjct: 436 EWKVWEQYVTDTLQHALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKW 495 Query: 434 LGEQAFRDGIRKYMAAHAYSNSTTADLWQALESSGGKTITGIAASFTEQDGVPLVVAEAD 493 LGE+ F G+ +Y+ Y N+ T DLW AL + GK + + +T++ G P++ D Sbjct: 496 LGEETFIKGVSQYLNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSED 555 Query: 494 CVGAAQRLTLRQDRFVIAPANDPPLPARNWQIPVAVGPSHGKPFDEILLKKSTNIPAGAC 553 G ++T RQ+R++ P + + +A+ +G +L ++S I Sbjct: 556 GNG---KITFRQNRYLSTADVKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELED- 611 Query: 554 GDAIKVNLGDVGYFRVEYGPKNRAALLNAFPQMQVADRLNVVTDSWALVQAGRAEAPSYL 613 KVN G + Y + A L + V DR+ +V D L +G ++L Sbjct: 612 PTFFKVNSEQSGIYITSYTDERWAKLGQQADLLSVEDRVGLVADVKTLSASGYTSTTNFL 671 Query: 614 ALLDALDAGDHRAVWDQVISTFATLDR--LSRGRTERPVIQAYARARLRPVFDRIGWDGA 671 L+ + VWDQ+I++ +++ L + + + + + + + +GW+ Sbjct: 672 NLVSKWNNEKSFVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFK 731 Query: 672 GSGDDDTALLRASLISTLGDLGDAAIVAEAKRRFAAFAD-DPNSLPTALRDAVTHVVGVT 730 S T L+ ++ DA + A + F + + ++P ++ V + V Sbjct: 732 SSDSFSTQRLKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARV 791 Query: 731 ADRATYDQLLALARNSTATNERLRYYLAAASARDAELARATLALTLTGELPDTIVTGMIN 790 Y+++ + + + +E+L + ++ +L TL G + + + + Sbjct: 792 GGAENYEKVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQ 851 Query: 791 AVASAGEQPQLAWDFVRTNFDTLLARQGPNFR--DQFVPNFMTNFTDEAHAAELAAFAPS 848 + + E + W++V+ N+D L+ R P V + FT E+ F + Sbjct: 852 GMRAHQEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFAT 911 Query: 849 QSTTGGRVMVARSVQAIAISA 869 +ST G +A+S+ I A Sbjct: 912 KSTKGFDQSLAQSLDTITSKA 932 >YHR047c [E] COG0308 Aminopeptidase N Sce Saccharomyces cerevisiae Length = 856 Score = 381 bits (978), Expect = e-105, Method: Compositional matrix adjust. Identities = 247/859 (28%), Positives = 416/859 (48%), Gaps = 27/859 (3%) Query: 45 LPKTVVPLHYAIELRPDITSLALPGVETVDIEVREATAQLTLNAVNTTFTDVTID----D 100 LP V PLHY I L P+ + G +D+++ + + +N+V + ++ + Sbjct: 6 LPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHS----INSVQINYLEIDFHSARIE 61 Query: 101 SAQRAEVATDATAQTATLTFAKPLAAG---RHKLRIVFAAQINKFGTGLFSVDYPTR-TG 156 EV + Q ATL F KL I+F+ +N G + Y + TG Sbjct: 62 GVNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYTDKVTG 121 Query: 157 -IKRMISSKLEPADARRIFPCWDEPSFKASFALTVVIPRNLLAVGNMPVTDEEPVAGDLK 215 K M ++++E DARR FPC+DEP+ KA+FA+T+V L + NM V +E G K Sbjct: 122 ETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGK-K 180 Query: 216 KVAFAPTPKMSSYLFVLAVGELERVTADAGGVTVGVVTTEGKGGQGRFALDSAVKLLAYY 275 F TPKMS+YL V +L V ++ + V V +T G G+FA + A + L ++ Sbjct: 181 YTTFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLRFF 240 Query: 276 NDYFGVKYPLPKLDLIAVPGGFGGAMENWGGITFFESRLLFDPAISAETARRGIFAIIAH 335 D F ++YPLPK+D++AV GAMENWG +T+ LL D S+ + + +I H Sbjct: 241 EDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQH 300 Query: 336 EMAHMWFGDLVTMAWWDNLWLNEGFASWMATKASEQFYPEWQGWLNGYGAK-QFAMTLDA 394 E+AH WFG+LVTM WW+ LWLNEGFA+WM+ + +F PEW+ W Q A+ LD+ Sbjct: 301 ELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDS 360 Query: 395 RRTSHPVQQPIADHSEAVTAFDAITYNKGQALIRMLETYLGEQAFRDGIRKYMAAHAYSN 454 R+SHP++ P+ + E FDAI+Y+KG +L+RM+ +LGE+ F G+ +Y+ Y N Sbjct: 361 LRSSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGN 420 Query: 455 STTADLWQALESSGGKTITGIAASFTEQDGVPLVVAEADCVGAAQRLTLRQDRFVIAPAN 514 + T DLW AL + GK + + +T++ G P++ + ++TL Q R++ Sbjct: 421 AKTGDLWDALADASGKDVCSVMNIWTKRVGFPVLSVKEH----KNKITLTQHRYLSTGDV 476 Query: 515 DPPLPARNWQIPVAVGPSHGKPFDEILLKKSTNIPAGACGDAIKVNLGDVGYFRVEYGPK 574 + I +A+ S G +L +KS + K+N G F Y + Sbjct: 477 KEEEDTTIYPILLALKDSTGIDNTLVLNEKSATFEL-KNEEFFKINGDQSGIFITSYSDE 535 Query: 575 NRAALLNAFPQMQVADRLNVVTDSWALVQAGRAEAPSYLALLDALDAGDHRAVWDQVIST 634 A L + V DR+ +V D+ AL +G ++L L+ D VW+Q+I++ Sbjct: 536 RWAKLSKQANLLSVEDRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINS 595 Query: 635 FATLDRLSRGRTERPVIQAYARARLRPVFDRIGWDGAGSGDDDT---ALLRASLISTLGD 691 + L E ++ A + L V +++ G G+DD+ L+ +L S Sbjct: 596 LSALKSTWVFEPE-DILNALDKFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACT 654 Query: 692 LGDAAIVAEAKRRFAAFAD-DPNSLPTALRDAVTHVVGVTADRATYDQLLALARNSTATN 750 G+ + + A F +A+ + ++P + V + V Y+++ + +N ++ Sbjct: 655 SGNEKMQSIAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSE 714 Query: 751 ERLRYYLAAASARDAELARATLALTLTGELPDTIVTGMINAVASAGEQPQLAWDFVRTNF 810 E++ A D EL TL+ L G + + + + + + W +++ ++ Sbjct: 715 EKIIALRALGRFEDKELLERTLSYLLDGTVLNQDFYIPMQGIRVHKKGIERLWAWMQEHW 774 Query: 811 DTLLARQGPN--FRDQFVPNFMTNFTDEAHAAELAAFAPSQSTTGGRVMVARSVQAIAIS 868 D + R P + +TNFT +++AF + T G +A+++ I Sbjct: 775 DEIAKRLQPGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSK 834 Query: 869 ADLAARVLPAADDWIRAHK 887 A +R ++R H+ Sbjct: 835 AQWVSRDREIVATYLREHE 853 >SPBC1921.05 [E] COG0308 Aminopeptidase N Spo Schizosaccharomyces pombe Length = 882 Score = 360 bits (925), Expect = 7e-99, Method: Compositional matrix adjust. Identities = 252/878 (28%), Positives = 415/878 (47%), Gaps = 40/878 (4%) Query: 39 DRTPGKLPKTVVPLHYAIELRPDITSLALPGVETVDIEVREATAQLTLNAVNTTFTDVTI 98 D+ LPK V P+HY + L PD+ + G V ++V E + +TL+ +N + Sbjct: 14 DKNRNLLPKNVKPIHYDLSLYPDLETFTYGGKVVVTLDVLEDSNSITLHGINLRILTAAL 73 Query: 99 DDSAQRAEVATDATA-QTATLTFAKPLAAGRHK-LRIVFAAQINKFGTGLFSVDYPTRTG 156 + +Q + + + L F + A L + F A+I+ G + Y G Sbjct: 74 EWGSQTVWASEVSYGDERIVLQFPSTVPANSVAVLTLPFTARISSGMEGFYRSSYVDSDG 133 Query: 157 -IKRMISSKLEPADARRIFPCWDEPSFKASFALTVVIPRNLLAVGNMPVTDEEPVAGDLK 215 K + ++++EP ARR FPCWDEP+ KA+F + + N + NM EE V LK Sbjct: 134 NTKYLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNMNAV-EETVKDGLK 192 Query: 216 KVAFAPTPKMSSYLFVLAVGELERVTADAGG-----VTVGVVTTEGKGGQGRFALDSAVK 270 FA T +MS+YL V ELE V G + V V TT G QG+FA + K Sbjct: 193 TARFAETCRMSTYLLAWIVAELEYVEYFTPGKHCPRLPVRVYTTPGFSEQGKFAAELGAK 252 Query: 271 LLAYYNDYFGVKYPLPKLDLIAVPGGFGGAMENWGGITFFESRLLFDPAISAETARRGIF 330 L +++ FG YPLPK D++A+P GAMENWG +T+ + +L SA T + Sbjct: 253 TLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILVSED-SAATVIERVA 311 Query: 331 AIIAHEMAHMWFGDLVTMAWWDNLWLNEGFASWMATKASEQFYPEWQGWLNGYGAK-QFA 389 ++ HE+AH WFG+LVTM +WD LWLNEGFA+WM+ + FYPEW+ W + Q A Sbjct: 312 EVVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNHFYPEWKVWESYVTDNLQSA 371 Query: 390 MTLDARRTSHPVQQPIADHSEAVTAFDAITYNKGQALIRMLETYLGEQAFRDGIRKYMAA 449 ++LDA R+SHP++ PI E FDAI+Y+KG +IRM+ Y+GE F GI+KY++ Sbjct: 372 LSLDALRSSHPIEVPIMHDYEINQIFDAISYSKGSCVIRMVSKYVGEDTFIKGIQKYISK 431 Query: 450 HAYSNSTTADLWQALESSGGKTITGIAASFTEQDGVPLVVAEADCVGAAQRLTLRQDRFV 509 H Y N+ T DLW AL + G+ I+ ++T++ G P++ G L + Q RF+ Sbjct: 432 HRYGNTVTEDLWAALSAESGQDISSTMHNWTKKTGYPVLSVSETNDG---ELLIEQHRFL 488 Query: 510 ----IAPANDP-----PLPARNWQIPVAVGPSHGKPFDEILLKKSTNIPAGACG-DAIKV 559 + P D PL + + AV +L +S I ++ K+ Sbjct: 489 STGDVKPEEDTVIYWAPLKLKTMKDGKAVVDEKA-----VLSDRSKKIKVDKEALESYKL 543 Query: 560 NLGDVGYFRVEYGPKNRAAL----LNAFPQMQVADRLNVVTDSWALVQAGRAEAPSYLAL 615 N G +RV Y + L + + V DR ++ D +L +AG + S L L Sbjct: 544 NSEQSGIYRVNYSADHLKKLSQIAVEKPDYLSVEDRAGLIADVASLSRAGYGKVSSTLDL 603 Query: 616 LDALDAGDHRAVWDQVISTFATLDRLSRGRTERPVIQAYARARLRPVFDR---IGWDGAG 672 + + V+ ++++ + R + +I A + L + +GW+ Sbjct: 604 IKTWKDEPNFVVFAEMLARLNGIKSTLRFESS-DIIAAMKKLVLEVSATKAHSLGWEFKA 662 Query: 673 SGDDDTALLRASLISTLGDLGDAAIVAEAKRRFAAFAD-DPNSLPTALRDAVTHVVGVTA 731 + D ++++ + G GD +V +A +F A+A + +++ LR AV ++ Sbjct: 663 NDDHIIRQFKSTVYNYAGLFGDDKVVKDALSKFDAYASGNKSAINDNLRSAVFNIAIRYG 722 Query: 732 DRATYDQLLALARNSTATNERLRYYLAAASARDAELARATLALTLTGELPDTIVTGMINA 791 ++DQLL + + R A D + + TL LTL + + + ++ Sbjct: 723 GAKSWDQLLEIYTKTNDPYVRNSCLRAFGVTEDEKYIQKTLDLTLDPIVKEQDIYLILVT 782 Query: 792 VASAGEQPQLAWDFVRTNFDTLLARQ--GPNFRDQFVPNFMTNFTDEAHAAELAAFAPSQ 849 +++ W F +N+D LL+R R V + FT + ++ F + Sbjct: 783 LSTHKNGVLAMWKFATSNWDKLLSRLPVAGTMRGYVVRFVTSGFTHASAIDKIKEFFADK 842 Query: 850 STTGGRVMVARSVQAIAISADLAARVLPAADDWIRAHK 887 T + +S+ I+ ++ + L W++ ++ Sbjct: 843 DTKLYERALQQSLDTISANSSFIDKSLDDITRWLKENR 880 >SSO2154 [E] COG0308 Aminopeptidase N Sso Sulfolobus solfataricus Length = 785 Score = 319 bits (818), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 207/660 (31%), Positives = 330/660 (50%), Gaps = 43/660 (6%) Query: 160 MISSKLEPADARRIFPCWDEPSFKASFALTVVIPRNLLAVGNMPVTDEEPVAGDLKKVAF 219 +IS++ E AR PC+D P+ KA F LTV + + L + NMPV E+ G + F Sbjct: 100 VISTQFEATHARDFIPCFDHPAMKARFKLTVRVDKGLKVISNMPVVREKEENGKVV-YEF 158 Query: 220 APTPKMSSYLFVLAVGELERVTADAGGVTVGVVTTEGKGGQGRFALDSAVKLLAYYNDYF 279 TPKMS+YL L +G E + + T+ V T GK +GRF++ + + +Y YF Sbjct: 159 DETPKMSTYLLYLGIGNFEEIRDEGKIPTIIVATIPGKVQKGRFSMQISRNSIEFYEKYF 218 Query: 280 GVKYPLPKLDLIAVPGGFGGAMENWGGITFFESRLLFDPAISAETARRGIFAIIAHEMAH 339 + Y LPK+ LIA+P GAMENWG ITF E+ LL D + S R + ++AHE+AH Sbjct: 219 EIPYQLPKVHLIAIPEFAYGAMENWGAITFRETALLADDSSSVYQKFR-VAEVVAHELAH 277 Query: 340 MWFGDLVTMAWWDNLWLNEGFASWMATKASEQFYPEWQGW----LNGYGAKQFAMTLDAR 395 WFG+LVT+ WWD+LWLNE FA++M+ KA Q +P W W LN A+ D+ Sbjct: 278 QWFGNLVTLKWWDDLWLNESFATFMSHKAISQLFPSWNFWDYFVLNQTSR---ALEKDSV 334 Query: 396 RTSHPVQQPIADHSEAVTAFDAITYNKGQALIRMLETYLGEQAFRDGIRKYMAAHAYSNS 455 T+HP++ + D +E FD I+Y KG +++RM+E Y+GE+ FR G+ Y+ +YSN+ Sbjct: 335 STTHPIEAHVRDPNEVEQMFDDISYGKGASILRMIEAYVGEENFRRGVVNYLKKFSYSNA 394 Query: 456 TTADLWQALESSGGKTITGIAASFTEQDGVPLVVAEADCVGAAQRLTLRQDRFVIAPAND 515 +DLW ++ G I+ I A + + G P+V + +R++L Q+RF + + Sbjct: 395 QGSDLWNSISEVYGSDISPIMADWITKPGYPMVRVSV----SGKRVSLEQERFSLIGNVE 450 Query: 516 PPLPARNWQIPVAVGPSHGKPFDEILLKKSTNIPAGACGDAIKVNLGDVGYFRVEYGPKN 575 L ++IP+ + +GK +L K+ + ++KVN+ G++RV Y N Sbjct: 451 NLL----YKIPLTM-EVNGKVVTHLLDKERDTMVFEEDVKSLKVNVNRTGFYRVFY-YNN 504 Query: 576 RAALLNAFPQMQVADRLNVVTDSWALVQAGRAEAPSYLALLDALDAGDHRAVWDQVISTF 635 + N+ + D+ ++ D WA + AG+ Y ++ +++ + Sbjct: 505 SDLVFNS--NLSELDKWGIINDYWAFLLAGKIGFKEYERVISKFFNDKDFLPVNELSNEL 562 Query: 636 ATLDRLSRGRTERPVIQAYARARLRPVFDRIGWDGAGSGDDDTALLRASLISTLGDLGDA 695 TL ++ + + + + + R +L+ W S D+ L ++++ L A Sbjct: 563 FTLHAINPDKYQ-GIAKEFHRIQLK------NW--RNSKDELGRLTYSNILYRL-----A 608 Query: 696 AIVAEAKRRFAAFADDPNSLPTALRDAVTHVVGVTADRATYDQLLALARNSTATNERLRY 755 AI E + SL + R V +T + + D+LL R T E+LRY Sbjct: 609 AIDDEFSLGLSELFRFYGSLDSDTRQGVAVAYAITYEDNSVDELLERFRKETFDEEKLRY 668 Query: 756 YLAAASARDAELARATLALTLTGE-----LPDTIVTGMINAVASAGEQPQLAWDFVRTNF 810 A R L TL+L L+GE +P T+ T N A + L W + NF Sbjct: 669 LTAMLFFRKPYLVGNTLSLILSGEIKKQDIPLTLSTAAYNPYAKSA---VLNWIKMHINF 725 >TVN0800 [E] COG0308 Aminopeptidase N Tvo Thermoplasma volcanium Length = 779 Score = 311 bits (797), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 179/587 (30%), Positives = 303/587 (51%), Gaps = 34/587 (5%) Query: 53 HYAIELRPDITSLALPGVETVDIEVREATAQLTLNAVNTTFTDVTIDDSAQRAEVATDAT 112 Y + L D+ S G ET+ ++ L+AV + ++ S + E + Sbjct: 5 EYDLTLDLDLQSKTFHGTETIS----ASSGDFVLDAVGFNIEWIKVNGSDAKFEYDGNLL 60 Query: 113 AQTATLTFAKPLAAGRHKLRIVFAAQINKFGTGLFSVDYPTRTGIKRMISSKLEPADARR 172 T K+ I ++ +I+ +G++ + R M+++ E DARR Sbjct: 61 KINGLET--------AQKVEISYSGKISDSLSGIY---FAGRES-NGMVTTHFEATDARR 108 Query: 173 IFPCWDEPSFKASFALTVVIPRNLLAVGNMPVTDEEPVAGDLKKVAFAPTPKMSSYLFVL 232 +FPC D P++KA F++T+VI ++ A+ NMP+ E D K V F TP+MS+YL + Sbjct: 109 MFPCIDHPAYKAVFSITLVIDKDYDAISNMPIKKVE--TSDRKIVEFEKTPRMSTYLLYI 166 Query: 233 AVGELERVTADAGGVTVGVVTTEGKGGQGRFALDSAVKLLAYYNDYFGVKYPLPKLDLIA 292 VG+ + + + + K + ++ +D A + + +Y YFG+ Y LPK+ LI+ Sbjct: 167 GVGKFKYASERYKDREI--ILASLKDIKSKYPIDIAKRSIEFYEGYFGIPYALPKMHLIS 224 Query: 293 VPGGFGGAMENWGGITFFESRLLFDPAISAETARRGIFAIIAHEMAHMWFGDLVTMAWWD 352 VP GAMENWG ITF E L +A T R +IAHE+AH WFGDLVTM WW+ Sbjct: 225 VPEFGAGAMENWGAITFREIYLDIADNSAASTLRLSA-NVIAHEIAHQWFGDLVTMKWWN 283 Query: 353 NLWLNEGFASWMATKASEQFYPEWQGWLNGYGAKQF-AMTLDARRTSHPVQQPIADHSEA 411 +LWLNE FA++M+ K + +PEWQ W + + ++ A+ D+ + +HP++ + D E Sbjct: 284 DLWLNESFATFMSYKTMDTIHPEWQFWGDFFVSRTSGALRSDSLKNTHPIEVDVKDPDEI 343 Query: 412 VTAFDAITYNKGQALIRMLETYLGEQAFRDGIRKYMAAHAYSNSTTADLWQALESSGGKT 471 FD I+Y KG +++RM+E Y+G + FR GI KY+ HAY N+ +DLW A+E+ GK Sbjct: 344 SQIFDEISYGKGASILRMIEDYVGAEDFRKGISKYLKEHAYGNAEGSDLWNAIETESGKP 403 Query: 472 ITGIAASFTEQDGVPLVVAEADCVGAAQRLTLRQDRFVIAPANDPPLPARNWQIPVAVGP 531 + I ++ + G P++ D G + + Q RF + W +PV + Sbjct: 404 VNRIMEAWITKAGYPILKVSQDKTG----IKVMQSRFFLGGGE----STDRWPVPVKMRL 455 Query: 532 SHGKPFDEILLKKSTNIPAGACGDAIKVNLGDVGYFRVEYGPKNRAALLNAFPQMQVADR 591 ++G ++LL++ + + D IK+N ++G++RV Y + + ++ ++ DR Sbjct: 456 NNG--ISQMLLEEESTVITDK--DVIKLNADNLGFYRVNYDDETFSKIIENMDKLTPLDR 511 Query: 592 LNVVTDSWALVQAGRAEAPSYLALLDALDAGDHRAVWDQVISTFATL 638 + +V D +A + AG +Y + + V +++ F L Sbjct: 512 VGLVDDLFAFLMAGVITPDTYKNRIKSFFNDKDANVISNIVNQFEYL 558