BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0218.0046.p (1219 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2282_4 [T] COG0642 Signal transduction histidine kinase Nos N... 254 1e-66 alr2739 [T] COG0642 Signal transduction histidine kinase Nos Nos... 153 3e-36 VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibr... 152 6e-36 all1388_2 [T] COG0642 Signal transduction histidine kinase Nos N... 150 2e-35 alr4586 [T] COG0642 Signal transduction histidine kinase Nos Nos... 148 6e-35 >all2282_4 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 301 Score = 254 bits (649), Expect = 1e-66, Method: Composition-based stats. Identities = 137/292 (46%), Positives = 194/292 (66%), Gaps = 17/292 (5%) Query: 927 EEVQARTRELAKSLDE----LRAAQDRLVQTEKLASLGQLTAGIAHEIKNPLNFVNNFSA 982 E+++ +R L ++E L+AAQ++++ EKLASLG LTAG+AHEI+NPLNFVNNF+A Sbjct: 1 EQLEYYSRNLEIKVEERTSQLKAAQNKIIAQEKLASLGLLTAGVAHEIRNPLNFVNNFAA 60 Query: 983 LSAELIGELTELLGNAELDDRIRTDVDELAQMLKGNLDKVV-------QHGKRADSIVKN 1035 +SAEL E+ AE++++ T EL + +KG + +V Q G RAD+I++N Sbjct: 61 ISAELGKEIL-----AEIENQSETLNSELIEYIKGTITDIVDNSVEIEQQGLRADNIIQN 115 Query: 1036 MLLHSREGTGDR-RPTDINAIVEESLNLAYHGARAEKSGFNLTLKRDLDPHAGTAEVYPQ 1094 MLL +R + ++ + TDIN+++E ++ LAYH + +GFN+T+ D D + Q Sbjct: 116 MLLLARSDSNNQPQFTDINSLLETAVQLAYHSLSNKLNGFNITIDTDYDSSLPEVAIIFQ 175 Query: 1095 EITRVLLNLISNGFYAAYKRKEAHGDAFEPTLSATTRALANEVEIRIRDNGVGIPEEVKA 1154 +I+R L+N++ N YAAYK+K+ GD F P L T+ + I IRDNG GI EV Sbjct: 176 DISRALINIVDNACYAAYKKKQEVGDKFIPKLFVKTQNQGESLLIIIRDNGQGIAPEVID 235 Query: 1155 KIFNPFFTTKPAGEGTGLGLSMSHDIVVKQHGGRITVETEPGAFTEFIITLP 1206 KIFNPFFTTKP GEGTGLGLS+ HDIVV QH G I + TE G +TEF++T+P Sbjct: 236 KIFNPFFTTKPPGEGTGLGLSLIHDIVVGQHQGDIKINTEVGEYTEFVLTIP 287 >alr2739 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 591 Score = 153 bits (386), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 116/345 (33%), Positives = 181/345 (52%), Gaps = 44/345 (12%) Query: 899 QSFSDKQVTLLQ---TFADQAVIALGNVRLFEEVQARTR---ELAKSLDELRAAQDRLVQ 952 Q+F+D V L Q T + N RL E+ R + EL K+L EL+ Q +L+Q Sbjct: 236 QAFNDMAVKLSQSRETLMKNTELTNMNQRLELEIAERKQAELELQKALQELQQTQAQLIQ 295 Query: 953 TEKLASLGQLTAGIAHEIKNPLNFVNNFSALSAELIGELTEL--LGNAELDD---RIRTD 1007 TEK++SLGQL AG+AHEI NP++F+ + E +L EL L EL + I+ Sbjct: 296 TEKMSSLGQLVAGVAHEINNPVSFIYGNITHAKEYTEKLLELIHLYQQELTEPSAVIQEK 355 Query: 1008 VDEL-AQMLKGNLDKVVQHGK----RADSIVKNMLLHSREGTGDRRPTDINAIVEESLNL 1062 + E+ + L+ +L K++ K R IV ++ SR + + DI+ +E +L + Sbjct: 356 IAEIDLEFLQEDLPKILSSMKMGSQRIQQIVLSLRNFSRLDEAEMKEVDIHEGIESTLLI 415 Query: 1063 AYHGARAEKSGFNLTLKRD------LDPHAGTAEVYPQEITRVLLNLISN---------- 1106 + +A+ +N+ + ++ ++ HAG ++ +V +N+I+N Sbjct: 416 LQNRFKAKSQSYNIEIIKEYGQLPLVECHAG-------QLNQVFMNIINNAVDALEGSVV 468 Query: 1107 -GFYAAYKRKEAHGDAF---EPTLSATTRALANE-VEIRIRDNGVGIPEEVKAKIFNPFF 1161 G ++ K + + P +S T N V IRI DNG GI + V K+F+PFF Sbjct: 469 SGQWSIVNGKTTNNERLTNNSPQISIRTEINNNNRVVIRIADNGPGINQLVMQKLFDPFF 528 Query: 1162 TTKPAGEGTGLGLSMSHDIVVKQHGGRITVETEPGAFTEFIITLP 1206 TTKP G+GTGLGLS+S+ IVV +H G + E+E G TEF I +P Sbjct: 529 TTKPVGQGTGLGLSISYQIVVDKHSGVLRCESEIGKGTEFWIEIP 573 >VC1084 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 439 Score = 152 bits (383), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 104/304 (34%), Positives = 169/304 (55%), Gaps = 45/304 (14%) Query: 924 RLFEEVQARTRELAKSLDELRAAQDRLVQTEKLASLGQLTAGIAHEIKNPLNFV-NNFSA 982 +L EE Q++ + L K L++ AQ +L+Q+EK+AS+GQL+AGIAHEI NP+ F+ +N Sbjct: 144 KLEEEHQSQ-KVLIKKLED---AQGQLIQSEKMASIGQLSAGIAHEINNPVGFITSNLQT 199 Query: 983 LS------AELIGELTELLGNAELDDRIRTDVDELAQML--KGNLDKVVQH--------- 1025 LS +++ +T+ +G ++ T ++E Q + +G +D +++ Sbjct: 200 LSDYFNSLEKVLKSITQTIGQSK-----DTALNEACQKILKQGQVDFILEDTAELITESL 254 Query: 1026 --GKRADSIVKNMLLHSREGTGDRRPTDINAIVEESLNLAYHGARAEKSGFNLTLKRDLD 1083 R SIVKN+ S + ++ +E +L + + + +N+TL++ Sbjct: 255 EGSSRVMSIVKNLKEFSHVDRSEWSYANLENCIESTLKIINNEIK-----YNITLEKHYA 309 Query: 1084 PHAGTAEVYPQEITRVLLNLISNGFYAAYKRKEAHGDAFEPTLSATTRALANE-VEIRIR 1142 + P +I +VLLN++ N +H E T++ T ++ ++ VEI IR Sbjct: 310 ANVPDVFCQPMQINQVLLNILVNA---------SHAIKGEGTITITLQSAGDDFVEIHIR 360 Query: 1143 DNGVGIPEEVKAKIFNPFFTTKPAGEGTGLGLSMSHDIVVKQHGGRITVETEPGAFTEFI 1202 D G GIPEE++ +IF PFFTTKP G GTGLGLS+S+ I+ K H G I+V +E G +EF Sbjct: 361 DTGCGIPEEIRERIFEPFFTTKPVGSGTGLGLSVSYGIINK-HNGTISVTSEVGKGSEFT 419 Query: 1203 ITLP 1206 I LP Sbjct: 420 IRLP 423 >all1388_2 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 281 Score = 150 bits (378), Expect = 2e-35, Method: Composition-based stats. Identities = 95/281 (33%), Positives = 156/281 (55%), Gaps = 19/281 (6%) Query: 942 ELRAAQDRLVQTEKLASLGQLTAGIAHEIKNPLNFVNNFSALSAELIGELTELL------ 995 EL+ Q +L+QTEK+ASLGQ+ AGIAHE+ NP+NF+ + + E+ +LL Sbjct: 2 ELQKTQSQLIQTEKIASLGQMAAGIAHEVNNPINFIAGNLNFVQKYVQEVVDLLYLYQKH 61 Query: 996 ---GNAELDDRI-RTDVDELAQMLKGNLDKVVQHGKRADSIVKNMLLHSREGTGDRRPTD 1051 AE+ + I +TD+ L L ++ + R IV ++ SR ++ + Sbjct: 62 FPNPPAEIQNAINQTDLTYLLDDLSNVINSMRVGTDRVQEIVSSLNKFSRHKETGKKLAN 121 Query: 1052 INAIVEESLNLAYH--GARAEKSGFNLTLKRDLDPHAGTAEVYPQEITRVLLNLISNGFY 1109 ++ ++ +L + H A +E+ + K P E Y EI++V +NLI+N Sbjct: 122 LHEAIDNTLLILGHRLKANSERPAIEIVKKYGNLP---LIECYSGEISQVFMNLIANAID 178 Query: 1110 A--AYKRKEAHGDAFEPT--LSATTRALANEVEIRIRDNGVGIPEEVKAKIFNPFFTTKP 1165 A ++ + + + E T + TT + ++ +I DNG GI EE++++IFN F+TTKP Sbjct: 179 AIEETQKNQNYYEISENTGVIRITTELIGEQIICKIADNGGGISEEMQSQIFNAFYTTKP 238 Query: 1166 AGEGTGLGLSMSHDIVVKQHGGRITVETEPGAFTEFIITLP 1206 G+GTGLGLS+++ IV H G+I+ ++PGA EF+I LP Sbjct: 239 IGKGTGLGLSIAYQIVTVNHHGKISCHSQPGAGLEFMIELP 279 >alr4586 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 688 Score = 148 bits (374), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 108/348 (31%), Positives = 182/348 (52%), Gaps = 49/348 (14%) Query: 904 KQVTLL--QTFADQAVIALGNVRLFEEVQARTRELAK-------SLDELRAAQDRLVQTE 954 +QV LL + + Q + N L + V+ RT+ L + +L EL+ Q +L+Q E Sbjct: 340 QQVKLLLAEQYEGQKKLEAYNQTLEQRVEERTQALQQKNISLRNTLRELKLTQSQLIQHE 399 Query: 955 KLASLGQLTAGIAHEIKNPLNFVNNFSALSAELIGELTELLG-------NAELDDRIRTD 1007 K++SLGQL AGIAHEI NP+NF+ + E I +L +L N E + + + Sbjct: 400 KMSSLGQLVAGIAHEINNPVNFIYGNLNYTDEYIQQLLKLFQLYQKYYPNPEREIQEAQE 459 Query: 1008 VDELAQMLKGNLDKVVQHGK----RADSIVKNMLLHSREGTGDRRPTDINAIVEESLNLA 1063 E+ +++ +L K++ K R IV ++ + SR + + D++ + +L + Sbjct: 460 EAEIEYVIE-DLPKILASMKIGASRIREIVLSLRIFSRLDEAEFKTADLHEGINSTLLIL 518 Query: 1064 YHGARA---------EKSGF--NLTLKRDLDPHAGTAEV------------YPQEITRVL 1100 H +A E++ NL K D H E+ + ++ +V Sbjct: 519 QHRIKAQTVKAIAYSERNDITDNLNKKEIFDKHRPQIEIVKEYGDIPKIPCFAGQMNQVF 578 Query: 1101 LNLISNGFYAAYKRKEAHGDAF--EPTLSATTRALANEVEIRIRDNGVGIPEEVKAKIFN 1158 +N+++N A +EA D EPT+ T+ + + I I DNG GIP+EV++++F+ Sbjct: 579 MNILANAIDAL---EEAFCDGLCPEPTIHITSSQVNESIVIAIADNGTGIPQEVQSRLFD 635 Query: 1159 PFFTTKPAGEGTGLGLSMSHDIVVKQHGGRITVETEPGAFTEFIITLP 1206 PFFTTKP G+GTG+GLS+S+ I+ ++HGG + + G T+F+IT+P Sbjct: 636 PFFTTKPVGKGTGMGLSISYQIITEKHGGTLQCISSSGQGTKFVITIP 683