BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0218.0038.p         (173 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc3261 [GER] COG0697 Permeases of the drug/metabolite transport...    72   8e-13
DR0135 [GER] COG0697 Permeases of the drug/metabolite transporte...    67   1e-11
STM1517 [GER] COG0697 Permeases of the drug/metabolite transport...    66   3e-11
ECs2140 [GER] COG0697 Permeases of the drug/metabolite transport...    65   6e-11
ydeD [GER] COG0697 Permeases of the drug/metabolite transporter ...    65   7e-11

>RSc3261 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT)
           superfamily Rso Ralstonia solanacearum
          Length = 308

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 54/170 (31%), Positives = 85/170 (50%), Gaps = 6/170 (3%)

Query: 2   AIAALGLLMI--CGTVG----YDFSVAAFAIIMICPISFAIGNLLLRQANGAPMFDLFAW 55
           A+AA GL MI   GT G       + A F + +   +S++ GN++ ++     +  L  W
Sbjct: 131 AVAACGLAMIGVAGTSGAGAATGMTTAGFLLTLCAALSWSSGNIVTKRIGPVNVVSLVVW 190

Query: 56  LCLSAAVPLTVLTLITNGPQPTWHALTHMSLTGLVCILCLGGISTSIAYWLWGRLLRDYP 115
             L   VP  +L+    GPQ   H+L ++  T +  I+ L   +T   Y LW RLL  Y 
Sbjct: 191 GALIPPVPFFLLSYWMEGPQQIAHSLANLGGTSIGAIVYLAFGATIFGYSLWSRLLARYA 250

Query: 116 AAQVVPFALLVPFVGSAASSIVFGEAFGRLRLAGMVTVIAGIAVMLLSKR 165
           A+QV P  LLVP VG  +++++ GE     +  G   V+AG+ + +   R
Sbjct: 251 ASQVAPLTLLVPVVGLVSAALLLGERLVPAQWLGGAVVMAGLLLNVFGGR 300


>DR0135 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT)
           superfamily Dra Deinococcus radiodurans
          Length = 325

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 45/159 (28%), Positives = 80/159 (50%)

Query: 7   GLLMICGTVGYDFSVAAFAIIMICPISFAIGNLLLRQANGAPMFDLFAWLCLSAAVPLTV 66
           G+ +I  T G+D       + +   + +AI NL+++ +  A  F L  W  L   +PL +
Sbjct: 135 GMALIGLTAGHDVPFFPLLLTLTAALGWAISNLVVKASPQANGFGLVVWSALIPPIPLAL 194

Query: 67  LTLITNGPQPTWHALTHMSLTGLVCILCLGGISTSIAYWLWGRLLRDYPAAQVVPFALLV 126
           L  +T G  P    LTH        +L +G  +T + + +W  L++ + A++V P +LLV
Sbjct: 195 LAGLTAGWGPVMQTLTHSDWKFWAAVLFMGLGNTVLGFGIWSGLIQRHGASRVAPLSLLV 254

Query: 127 PFVGSAASSIVFGEAFGRLRLAGMVTVIAGIAVMLLSKR 165
           P  G+ AS++ F E F   ++ G   + AG+ + +   R
Sbjct: 255 PVFGTLASALAFHEGFPPGKVLGAALIAAGLVLHVFGGR 293


>STM1517 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT)
           superfamily Sty Salmonella typhimurium LT2
          Length = 300

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 46/178 (25%), Positives = 94/178 (52%), Gaps = 6/178 (3%)

Query: 2   AIAALGLLMICGTV--GYDFSVAAFAIIMICPISFAIGNL----LLRQANGAPMFDLFAW 55
           A+A +G+L++      G   +++ F + +    S+A GN+    +++ +    +  L  W
Sbjct: 122 ALAIIGVLVLIEASLNGQHIAMSGFMLTLAAAFSWACGNIFNKKIMQHSPRPAVMSLVVW 181

Query: 56  LCLSAAVPLTVLTLITNGPQPTWHALTHMSLTGLVCILCLGGISTSIAYWLWGRLLRDYP 115
             L   +P  + +L+  G      +L  + +T ++ +L L  ++T + Y +WG LL  Y 
Sbjct: 182 SALIPILPFLLSSLLLEGADHITQSLITIDMTTILSLLYLAFVATILGYGIWGALLGRYE 241

Query: 116 AAQVVPFALLVPFVGSAASSIVFGEAFGRLRLAGMVTVIAGIAVMLLSKRPKAMPKVA 173
             +V P +LLVP VG A+++++ GE    ++LAG V ++AG+ + +   R +   +V+
Sbjct: 242 TWRVAPLSLLVPVVGLASAAVLLGETLTGMQLAGAVLIMAGLYINVFGFRVRRTARVS 299


>ECs2140 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT)
           superfamily Ecs Escherichia coli O157:H7
          Length = 299

 Score = 65.5 bits (158), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 42/161 (26%), Positives = 82/161 (50%), Gaps = 4/161 (2%)

Query: 16  GYDFSVAAFAIIMICPISFAIGNL----LLRQANGAPMFDLFAWLCLSAAVPLTVLTLIT 71
           G   ++  F + +    S+A GN+    ++  ++   +  L  W  L   +P  V +LI 
Sbjct: 137 GQHVAMLGFMLTLAAAFSWASGNIFNKKIMSHSSRPAVMSLVVWSALIPIIPFFVASLIL 196

Query: 72  NGPQPTWHALTHMSLTGLVCILCLGGISTSIAYWLWGRLLRDYPAAQVVPFALLVPFVGS 131
           +G     H+L  + +T ++ ++ L  ++T + Y +WG LL  Y   +V P +LLVP VG 
Sbjct: 197 DGSGKMIHSLVTIDMTTILALMYLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGL 256

Query: 132 AASSIVFGEAFGRLRLAGMVTVIAGIAVMLLSKRPKAMPKV 172
           A+++++  E    L+  G V ++AG+ + +   + +   KV
Sbjct: 257 ASAALLLDERLTGLQFLGAVLIMAGLYINVFGLQWRKAVKV 297


>ydeD [GER] COG0697 Permeases of the drug/metabolite transporter (DMT)
           superfamily Eco Escherichia coli K12
          Length = 266

 Score = 65.1 bits (157), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 4/161 (2%)

Query: 16  GYDFSVAAFAIIMICPISFAIGNL----LLRQANGAPMFDLFAWLCLSAAVPLTVLTLIT 71
           G   ++  F + +    S+A GN+    ++  +    +  L  W  L   +P  V +LI 
Sbjct: 104 GQHVAMLGFMLTLAAAFSWACGNIFNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLIL 163

Query: 72  NGPQPTWHALTHMSLTGLVCILCLGGISTSIAYWLWGRLLRDYPAAQVVPFALLVPFVGS 131
           +G     H+L  + +T ++ ++ L  ++T + Y +WG LL  Y   +V P +LLVP VG 
Sbjct: 164 DGSATMIHSLVTIDMTTILSLMYLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGL 223

Query: 132 AASSIVFGEAFGRLRLAGMVTVIAGIAVMLLSKRPKAMPKV 172
           A+++++  E    L+  G V ++ G+ + +   R +   KV
Sbjct: 224 ASAALLLDERLTGLQFLGAVLIMTGLYINVFGLRWRKAVKV 264