BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0217.0031.p (644 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_mmr [GEPR] COG0477 Permeases of the major facilitator superfa... 223 1e-57 mll2542 [GEPR] COG0477 Permeases of the major facilitator superf... 217 6e-56 XF1765 [GEPR] COG0477 Permeases of the major facilitator superfa... 214 6e-55 MT2395 [GEPR] COG0477 Permeases of the major facilitator superfa... 196 2e-49 Rv2333c [GEPR] COG0477 Permeases of the major facilitator superf... 195 3e-49 >BS_mmr [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 466 Score = 223 bits (568), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 126/324 (38%), Positives = 197/324 (60%), Gaps = 1/324 (0%) Query: 45 RRAASHQQSSGLGATLTLAAMSLGYGVVQLDVTIVNTALNAIGASLGGGVAELQWVVSAY 104 + + S Q+S+ L ++LG+ + LDVT+VN A+ + +L ++ + WVV Y Sbjct: 2 KNSGSIQESTSSTGISVLIVLALGFLMATLDVTVVNVAMADMKNTLSMSLSGVTWVVDGY 61 Query: 105 TIAFAAFILTAGALGDRIGAKRIFMAGFAIFTAASVGCAFAPDAATLIAARCVQGLAAAI 164 + FA+ +L GAL DR G+K I++ G A+F AS CA + + LIA R +QG+ AA+ Sbjct: 62 ILTFASLLLAGGALADRFGSKTIYILGLAVFVMASCLCAASINGQMLIAGRLIQGIGAAL 121 Query: 165 LVPNSLALLRHAYEDEQARGRAVGVWAAGASLALTAGPFVGGGLIALVGWRAIFLVNLPI 224 +P+SL+LL +Y DE+AR R G+WAA S A GPF+GG L+ L GW++IFL+N+PI Sbjct: 122 FMPSSLSLLAASYLDERARARMFGLWAALVSAASALGPFIGGVLVQLAGWQSIFLINVPI 181 Query: 225 GLAGLWLAWRFAGETARHQQHRLDLPGQVAAIAALGTLAGALIEGGALGWGSPFVIAGFA 284 G A L A+R + R+++ G + + ALG L+ ALI+G + GW SP ++ F Sbjct: 182 GAAALISAYRILSRVP-GKSSRVNIIGHLLGMMALGFLSYALIQGPSAGWRSPVILVAFT 240 Query: 285 LAAVFSVLFVWREARAPQPMLPLSLFRHRMFALTSLVGLLVNVAFYGLIFVLSLYFQQVN 344 A + VLF+ RE A P+LP SL+++ F+ +G L+N A +G +F+LSL+ Q+ Sbjct: 241 AAVLAFVLFLLREISAKTPILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAG 300 Query: 345 GLSALATGLAFVPMLGAVLPANLI 368 G S+ G+ +PM+ + NL+ Sbjct: 301 GASSFMAGVELLPMMAVFVIGNLL 324 >mll2542 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 505 Score = 217 bits (553), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 126/296 (42%), Positives = 175/296 (59%) Query: 62 LAAMSLGYGVVQLDVTIVNTALNAIGASLGGGVAELQWVVSAYTIAFAAFILTAGALGDR 121 +AA+ LG V LDV+IVN AL I +L LQWVV AYT+ +AF+L++G +GDR Sbjct: 9 VAAVYLGTFVALLDVSIVNVALPTIQQALHTDFGGLQWVVDAYTLCLSAFMLSSGLIGDR 68 Query: 122 IGAKRIFMAGFAIFTAASVGCAFAPDAATLIAARCVQGLAAAILVPNSLALLRHAYEDEQ 181 G KR ++AG IF A S+ CA AP+ L+A R VQG+A ++L+P +L++L A+ D + Sbjct: 69 YGRKRSWLAGVGIFVAGSLICAVAPNLPALLAGRVVQGIAGSLLIPGALSILTQAFPDPR 128 Query: 182 ARGRAVGVWAAGASLALTAGPFVGGGLIALVGWRAIFLVNLPIGLAGLWLAWRFAGETAR 241 R +G WAA A+++L GP +GG L+ VGW++IFL+NLP+GL + L ET+ Sbjct: 129 ERAGVIGGWAAFAAVSLVVGPVLGGILVQTVGWQSIFLINLPLGLFTIVLGAVSIEETSH 188 Query: 242 HQQHRLDLPGQVAAIAALGTLAGALIEGGALGWGSPFVIAGFALAAVFSVLFVWREARAP 301 + LDL G +I LG L LI G GWG P I + V +F+ EAR P Sbjct: 189 PEHAHLDLVGLALSILWLGALTFGLISAGESGWGDPRTIVAIIVGVVGLAVFLGFEARTP 248 Query: 302 QPMLPLSLFRHRMFALTSLVGLLVNVAFYGLIFVLSLYFQQVNGLSALATGLAFVP 357 +PMLPL LFR FA+ ++ + Y +F S++ QQV G S TGL P Sbjct: 249 RPMLPLGLFRDVRFAVANVASFALGFTSYSCVFFFSMFLQQVQGWSPTQTGLRMAP 304 >XF1765 [GEPR] COG0477 Permeases of the major facilitator superfamily Xfa Xylella fastidiosa 9a5c Length = 472 Score = 214 bits (544), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 140/299 (46%), Positives = 181/299 (60%), Gaps = 3/299 (1%) Query: 61 TLAAMSLGYGVVQLDVTIVNTALNAIGASLGGGVAELQWVVSAYTIAFAAFILTAGALGD 120 TL A+ LG+ V+ LD +VN AL + LG V LQWVV YT+ F A +L+AGAL D Sbjct: 28 TLIAVLLGFFVITLDAVVVNVALPTLAHDLGASVDGLQWVVDGYTLMFGALLLSAGALVD 87 Query: 121 RIGAKRIFMAGFAIFTAASVGCAFAPDAATLIAARCVQGLAAAILVPNSLALLRHAYEDE 180 RIGA+R F G +F AS+ C AP ATL+ AR VQG AA+++P S++L+R AY D Sbjct: 88 RIGARRAFGLGLVVFILASMACGGAPTLATLVVARLVQGAGAAVMMPASMSLIRQAYPDP 147 Query: 181 QARGRAVGVWAAGASLALTAGPFVGGGLIALVGWRAIFLVNLPIGLAGLWLAWRFAGETA 240 RG AV +WA G S+A T+GP +GG L++L WR IF VNLP+GL L LA+ + Sbjct: 148 VRRGHAVALWAMGGSVASTSGPVIGGWLVSL-DWRWIFFVNLPVGL--LTLAFLARTPAS 204 Query: 241 RHQQHRLDLPGQVAAIAALGTLAGALIEGGALGWGSPFVIAGFALAAVFSVLFVWREARA 300 + D GQV AI A+G L IE GA G G+ V+A F LA FVW + Sbjct: 205 PRRASPFDAVGQVTAILAMGALIYGAIEAGAQGLGATPVLAAFVLALAALAAFVWSQRCG 264 Query: 301 PQPMLPLSLFRHRMFALTSLVGLLVNVAFYGLIFVLSLYFQQVNGLSALATGLAFVPML 359 PM+P L R ++ VG V ++GL FV+SLY QQ GLSA ATG+AF+PM+ Sbjct: 265 AHPMVPPGLLAPRNARISMAVGFTFMVGYFGLPFVMSLYLQQHRGLSAPATGIAFLPMM 323 >MT2395 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 537 Score = 196 bits (497), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 124/303 (40%), Positives = 170/303 (56%) Query: 60 LTLAAMSLGYGVVQLDVTIVNTALNAIGASLGGGVAELQWVVSAYTIAFAAFILTAGALG 119 LTL A LG ++ LD IVN AL I S G LQWVV++Y++ A FI++A L Sbjct: 7 LTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLA 66 Query: 120 DRIGAKRIFMAGFAIFTAASVGCAFAPDAATLIAARCVQGLAAAILVPNSLALLRHAYED 179 D G +R ++ G ++FT S+ C AP A L AR QGL AA + SLAL+ A+ + Sbjct: 67 DLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPE 126 Query: 180 EQARGRAVGVWAAGASLALTAGPFVGGGLIALVGWRAIFLVNLPIGLAGLWLAWRFAGET 239 + + RA+G+W A AS+ T GP +GG L+ GWR+IF VNLP+G L+L + E+ Sbjct: 127 AKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEES 186 Query: 240 ARHQQHRLDLPGQVAAIAALGTLAGALIEGGALGWGSPFVIAGFALAAVFSVLFVWREAR 299 + R DL GQ+ I A+G L A+IEG +GW S I AAV LFVW E R Sbjct: 187 CNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERR 246 Query: 300 APQPMLPLSLFRHRMFALTSLVGLLVNVAFYGLIFVLSLYFQQVNGLSALATGLAFVPML 359 + PM+ L+LFR +AL V A YG++ + + + Q V G + TGL +P Sbjct: 247 SSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFS 306 Query: 360 GAV 362 AV Sbjct: 307 AAV 309 >Rv2333c [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 537 Score = 195 bits (495), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 124/303 (40%), Positives = 170/303 (56%) Query: 60 LTLAAMSLGYGVVQLDVTIVNTALNAIGASLGGGVAELQWVVSAYTIAFAAFILTAGALG 119 LTL A LG ++ LD IVN AL I S G LQWVV++Y++ A FI++A L Sbjct: 7 LTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLA 66 Query: 120 DRIGAKRIFMAGFAIFTAASVGCAFAPDAATLIAARCVQGLAAAILVPNSLALLRHAYED 179 D G +R ++ G ++FT S+ C AP A L AR QGL AA + SLAL+ A+ + Sbjct: 67 DLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPE 126 Query: 180 EQARGRAVGVWAAGASLALTAGPFVGGGLIALVGWRAIFLVNLPIGLAGLWLAWRFAGET 239 + + RA+G+W A AS+ T GP +GG L+ GWR+IF VNLP+G L+L + E+ Sbjct: 127 AKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEES 186 Query: 240 ARHQQHRLDLPGQVAAIAALGTLAGALIEGGALGWGSPFVIAGFALAAVFSVLFVWREAR 299 + R DL GQ+ I A+G L A+IEG +GW S I AAV LFVW E R Sbjct: 187 CNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERR 246 Query: 300 APQPMLPLSLFRHRMFALTSLVGLLVNVAFYGLIFVLSLYFQQVNGLSALATGLAFVPML 359 + PM+ L+LFR +AL V A YG++ + + + Q V G + TGL +P Sbjct: 247 SSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFS 306 Query: 360 GAV 362 AV Sbjct: 307 AAV 309