BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0213.0007.p (414 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc02603 [GEPR] COG0477 Permeases of the major facilitator super... 354 2e-97 AGc1918 [GEPR] COG0477 Permeases of the major facilitator superf... 349 8e-96 PA1286 [GEPR] COG0477 Permeases of the major facilitator superfa... 296 5e-80 NMA0047 [GEPR] COG0477 Permeases of the major facilitator superf... 248 1e-65 mll4118 [GEPR] COG0477 Permeases of the major facilitator superf... 134 4e-31 >SMc02603 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 412 Score = 354 bits (909), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 196/392 (50%), Positives = 260/392 (66%) Query: 18 PLVIIVCGCAIALLSFGPRSSLGFFVQPMSHEFTWGRDVFGLALALQNLLWGLGQPIAGA 77 P +IIV G IA+L+FGPRS++GFF PM E W R FGLA+A QNL WGLGQP GA Sbjct: 18 PWLIIVAGSIIAMLTFGPRSAMGFFQLPMLAEKGWDRTTFGLAMAFQNLCWGLGQPFFGA 77 Query: 78 IADRFGLLRVMVVGALLYAAGLLLMRYSTTPLSLDIGAGVLIGFGLSGSSFNLVLSAFSK 137 IAD+FG RV+ + L+YAAGL+LM ++ P+ L IG GVL+G G++ SF +VLSAF++ Sbjct: 78 IADKFGTWRVLALSGLVYAAGLILMAFADAPIWLHIGGGVLVGLGVASGSFGIVLSAFAR 137 Query: 138 LLPPAQRGIALGAGTAAGSFGQFLFAPFGVAMIDNFGWQTALLVFGALMLLILPLSLALS 197 + P QR +A G GTAAGS G FLFAP +I +GW +L+ G LMLL+ ++ L Sbjct: 138 NVAPEQRSLAFGIGTAAGSAGMFLFAPLSQGLISAYGWSDSLVYLGLLMLLVPLFAIPLR 197 Query: 198 TPPAETNDDAPADQQSFKTALAEAFGHRSYVLLVLGFFTCGFQLAFITVHLPAYLADRGI 257 + +Q+ AL EA GH+SY+LLV GFF CG+Q+AFIT H PAY+ D GI Sbjct: 198 GNASSGRQSEALFKQTVGEALKEALGHKSYLLLVSGFFVCGYQVAFITAHFPAYIGDIGI 257 Query: 258 PASTGGWVIAAIGLFNIVGSLSVGWLQNVFPKRYILSVIYFTRALSIIAFISFPITTFSA 317 A +A IG FNI+GS S G + + K Y L++IY R++ + AF+ P T S Sbjct: 258 DARYAVIALALIGFFNIIGSFSAGIIGQRYSKPYFLALIYLARSVVVSAFLLLPQTPTSV 317 Query: 318 IAFGAISGLTWLSTVPPTSALVALMFGTRWFATLYGFAFVSHQVGGFLGVWLGGIVFEQY 377 I F + GL WLSTVPPT+ LVA+MFGTR L G F+SHQ+G FLGVW+GG +++ + Sbjct: 318 IVFAVVMGLLWLSTVPPTNGLVAIMFGTRHLGLLGGIVFLSHQIGSFLGVWMGGYLYDHF 377 Query: 378 GSYTPIWWLSVLFGVLSALINLPIVEKPVVRP 409 GSY P+WW+ V GV +A+++ PI E+ V RP Sbjct: 378 GSYDPVWWVGVALGVFAAIVHWPIEERAVARP 409 >AGc1918 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 414 Score = 349 bits (895), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 193/410 (47%), Positives = 269/410 (65%), Gaps = 1/410 (0%) Query: 2 AATTGDLRPTSGTWRT-PLVIIVCGCAIALLSFGPRSSLGFFVQPMSHEFTWGRDVFGLA 60 A G + + T +T P +II G IA+++FGPRS++GFF PM + W R FGLA Sbjct: 3 ARCDGGMFMSQATRQTMPWLIIAAGSLIAVMTFGPRSAMGFFQLPMLADTGWDRSTFGLA 62 Query: 61 LALQNLLWGLGQPIAGAIADRFGLLRVMVVGALLYAAGLLLMRYSTTPLSLDIGAGVLIG 120 +ALQNL WGLGQP GAIAD++G RV+V+ +LYAAGL+ M + T+P L G GVL+G Sbjct: 63 MALQNLFWGLGQPFFGAIADKYGTGRVLVLSGILYAAGLVCMSFGTSPFWLHFGGGVLVG 122 Query: 121 FGLSGSSFNLVLSAFSKLLPPAQRGIALGAGTAAGSFGQFLFAPFGVAMIDNFGWQTALL 180 G++ SF+++LSAF++ + P QR +A G GTAAGS G FLFAP +I +GW +L+ Sbjct: 123 LGIAAGSFSVILSAFARHVTPQQRSLAFGIGTAAGSAGMFLFAPISQGLISAYGWSDSLV 182 Query: 181 VFGALMLLILPLSLALSTPPAETNDDAPADQQSFKTALAEAFGHRSYVLLVLGFFTCGFQ 240 A+M+L+ L+ + + + QQ+ AL EA GH+SY+LL GFF CGFQ Sbjct: 183 WLAAMMVLVPLLAWPMRGNSSSGSQSQAQFQQTVGEALKEALGHKSYLLLTTGFFVCGFQ 242 Query: 241 LAFITVHLPAYLADRGIPASTGGWVIAAIGLFNIVGSLSVGWLQNVFPKRYILSVIYFTR 300 +AFIT H PAYL D GI +A IG FNI+GSL+ G + + K Y+L+ IY R Sbjct: 243 VAFITAHFPAYLGDIGIEPRYAVIAMALIGFFNIIGSLAAGVIAQRYSKPYLLAYIYIAR 302 Query: 301 ALSIIAFISFPITTFSAIAFGAISGLTWLSTVPPTSALVALMFGTRWFATLYGFAFVSHQ 360 ++ + AF+ P + S I F + G+ WLSTVPPT+ALVA+MFGTR L G F++HQ Sbjct: 303 SVVVTAFLLLPQSPLSVILFASFMGILWLSTVPPTNALVAIMFGTRHLGMLGGVVFLTHQ 362 Query: 361 VGGFLGVWLGGIVFEQYGSYTPIWWLSVLFGVLSALINLPIVEKPVVRPV 410 +G FLGVWLGG +++++G+Y +WWL V G+ +A+++ PI E+P RPV Sbjct: 363 IGSFLGVWLGGFLYDRFGTYDIVWWLGVGMGIFAAIVHWPIQERPAPRPV 412 >PA1286 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 399 Score = 296 bits (758), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 185/393 (47%), Positives = 251/393 (63%), Gaps = 4/393 (1%) Query: 16 RTPLVIIVCGCAIALLSFGPRSSLGFFVQPMSHEFTWGRDVFGLALALQNLLWGLGQPIA 75 R I++ G I LS G R G F+ PMS +F WGR+VF A+ALQNL+WGL QP Sbjct: 3 RAAFWILLSGALILALSLGVRHGFGLFLAPMSADFGWGREVFAFAIALQNLVWGLAQPFT 62 Query: 76 GAIADRFGLLRVMVVGALLYAAGLLLMRYSTTPLSLDIGAGVLIGFGLSGSSFNLVLSAF 135 GA+ADR+G R ++VG LLYA GL+LM S + L + AG+LIG GLSG+SF+++L A Sbjct: 63 GALADRYGAARAVLVGGLLYALGLVLMGLSQSASGLSLSAGLLIGLGLSGTSFSVILGAV 122 Query: 136 SKLLPPAQRGIALGAGTAAGSFGQFLFAPFGVAMIDNFGWQTALLVFGALMLLILPLSLA 195 + +P QR +A+G +AAGSFGQF P + +I GW +ALL G L+ LI+PL+ Sbjct: 123 GRAVPAEQRSMAMGISSAAGSFGQFAMLPGTLGLIGWLGWSSALLALGLLVALIVPLAGL 182 Query: 196 LSTPPAETNDDAPADQQSFKTALAEAFGHRSYVLLVLGFFTCGFQLAFITVHLPAYLADR 255 + P +QS AL EA H + LL LGFF CGFQ+ FI VHLPAYL D+ Sbjct: 183 MKDRPLPPQ----GHEQSLGEALREACAHSGFWLLALGFFVCGFQVVFIGVHLPAYLVDQ 238 Query: 256 GIPASTGGWVIAAIGLFNIVGSLSVGWLQNVFPKRYILSVIYFTRALSIIAFISFPITTF 315 +PA G V+A +GLFN+ G+ GWL + K +L+ +Y R + I+ F+ P++ + Sbjct: 239 HLPAQVGTTVLALVGLFNVFGTYIAGWLGGRWSKPRLLTALYLVRGVVIVLFLWLPLSVY 298 Query: 316 SAIAFGAISGLTWLSTVPPTSALVALMFGTRWFATLYGFAFVSHQVGGFLGVWLGGIVFE 375 SA AFG GL WLSTVP T+ VA +FG R + L G F+ HQ+G FLG WLGG+V++ Sbjct: 299 SAYAFGVAMGLLWLSTVPLTNGTVATLFGVRNLSMLGGIVFLFHQLGAFLGGWLGGVVYD 358 Query: 376 QYGSYTPIWWLSVLFGVLSALINLPIVEKPVVR 408 + GSY +W LS+L +L+AL+N P+ E+PV R Sbjct: 359 RTGSYDLVWQLSILLSLLAALLNWPVRERPVAR 391 >NMA0047 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 405 Score = 248 bits (634), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 154/380 (40%), Positives = 217/380 (57%), Gaps = 4/380 (1%) Query: 28 IALLSFGPRSSLGFFVQPMSHEFTWGRDVFGLALALQNLLWGLGQPIAGAIADRFGLLRV 87 I L++ G R +LG FVQP+ + F L +A+ L+WG+ QP++GA+ADRFG RV Sbjct: 21 ILLITIGMRMTLGLFVQPVVNTTELSIAQFSLIIAVFQLMWGVSQPLSGALADRFGAFRV 80 Query: 88 MVVGALLYAAGLLLMRYSTTPLSLDIGAGVLIGFGLSGSSFNLVLSAFSKLLPPAQRGIA 147 + GA+L L+ T L I G+L+ FG F++++ + +P +RG+A Sbjct: 81 LSGGAVLLVCACLIAPNIPTYWGLMIAVGLLLAFGTGSGGFSIIMGQVAAQVPAHKRGLA 140 Query: 148 LGAGTAAGSFGQFLFAPF--GVAMIDNFGWQTALLVFGALMLLILPLS--LALSTPPAET 203 G A GS GQFLFAP G+ ++ GW V+GA+ LL LP+S LA A T Sbjct: 141 SGLVNAGGSAGQFLFAPLVQGLVVLPEVGWTGTFYVWGAIALLTLPVSWWLAGGNNAAHT 200 Query: 204 NDDAPADQQSFKTALAEAFGHRSYVLLVLGFFTCGFQLAFITVHLPAYLADRGIPASTGG 263 QS A+ AF SY+LL L FF CGF +AF+ HLP +A G+PA+ Sbjct: 201 QHAQATHGQSLGEAVKTAFKTPSYILLHLSFFACGFHIAFLVTHLPTEVALCGLPATVAS 260 Query: 264 WVIAAIGLFNIVGSLSVGWLQNVFPKRYILSVIYFTRALSIIAFISFPITTFSAIAFGAI 323 IA IGL NI G + GW + +Y+L +Y +RA I+ +I P T + F A Sbjct: 261 TSIAIIGLANIAGCIFSGWCTSRVRGKYVLFGLYASRAAMILIYIFSPKTDLNFYIFAAA 320 Query: 324 SGLTWLSTVPPTSALVALMFGTRWFATLYGFAFVSHQVGGFLGVWLGGIVFEQYGSYTPI 383 G TWL+TV PT+++ +FGTR+ ATL+G +SHQ+GGFLG ++GGIV Q+G Y + Sbjct: 321 LGFTWLATVTPTASITGKLFGTRYLATLFGLTMLSHQIGGFLGSYIGGIVITQFGDYGWM 380 Query: 384 WWLSVLFGVLSALINLPIVE 403 W+ L +AL+NLPI E Sbjct: 381 WYADALLAGTAALLNLPIRE 400 >mll4118 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 446 Score = 134 bits (337), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 126/417 (30%), Positives = 194/417 (46%), Gaps = 30/417 (7%) Query: 20 VIIVCGCAIALLSFGPRSSLGFFVQPMSHEFTWGRDVFGLALALQNLLWGLGQPIAGAIA 79 VI +C L++ G RS+ + P+ + F W RDV LA + LL+GL P A A+ Sbjct: 38 VIFLC----LLIAAGLRSAPAVMMLPLENSFGWRRDVISLAAGVGILLYGLTGPFAAALM 93 Query: 80 DRFGLLRVMVVGALLYAAGLLLMRYSTTPLSLDIGAGVLIGFGLSGSSFNLVLSAFSKLL 139 +R GL R ++ L+ + L T P L I GV G G SG+ +++ + Sbjct: 94 ERIGLRRTLIASLLVMSGSTALSLLMTKPWHLFITWGVFSGIG-SGAVASVLGATIVNRW 152 Query: 140 PPAQRGIALGAGTAAGSFGQFLFAPFGVAMIDNFGWQ----------TALLVFGALMLLI 189 RG+ +G +A+ + G +F P ++ + GW+ LL L++ Sbjct: 153 FKTNRGLVMGLMSASSATGLLVFLPLLASLAQSGGWKPVAVAVAVATACLLPLVWLLVPE 212 Query: 190 LPLSLALSTPPAETNDDAP---ADQQSFK----TALAEAFGHRSYVLLVLGFFTCGFQL- 241 P S+ + AE +D P A Q +F L A G R + L FF CGF Sbjct: 213 RPASIGMVRYGAEADDVPPVPPASQGNFLAHTLNTLRRAAGTRVFWYLFATFFVCGFTTN 272 Query: 242 AFITVHLPAYLADRGIPASTGGWVIAAIGLFNIVGSLSVGWLQNVFPKRYILSVIYFTRA 301 + HL A+ D GI +++ +G+F+++G+ GWL + F R +L V Y R Sbjct: 273 GLVGTHLIAFCGDMGIGEVQAAGLLSMMGIFDLIGTTLSGWLTDRFDPRKLLGVYYAIRG 332 Query: 302 LSIIAFISFPITTFSA---IAFGAISGLTWLSTVPPTSALVALMFGTRWFATLYGFAFVS 358 LS+I P + FSA I F + GL W++TVPPT L FG R ++G+ Sbjct: 333 LSLI---YLPYSGFSATSLIIFAVLYGLDWIATVPPTLRLANEAFGDRSGPIVFGWIVAG 389 Query: 359 HQVGGFLGVWLGGIVFEQYGSYTPIWWLSVLFGVLSALINLPI-VEKPVVRPVAQPA 414 HQVG GG + E G+Y + ++ + + +A I+L I +P P Q A Sbjct: 390 HQVGAATAAAFGGTMRELQGNYELAFLIAGMTAIAAACISLLINTSRPAFDPEPQAA 446